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Books in Immunology

Elsevier's Immunology collection equips researchers with valuable insights to address the complexities of the immune system and its role in health and disease, offering original research, insightful analysis, and current theory on diagnosing, managing, and advancing treatments for allergies, asthma, and immunologic disorders.

    • Micro- and Nanotechnology in Vaccine Development

      • 1st Edition
      • September 20, 2016
      • Mariusz Skwarczynski + 1 more
      • English
      • Hardback
        9 7 8 0 3 2 3 3 9 9 8 1 4
      • eBook
        9 7 8 0 3 2 3 4 0 0 2 9 9
      This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles.
    • Translational Neuroimmunology in Multiple Sclerosis

      • 1st Edition
      • May 10, 2016
      • Ruth Arnon + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 9 1 4 6
      • eBook
        9 7 8 0 1 2 8 0 2 0 0 7 4
      Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon—such as neuroprotective strategies, stem cells, and repair promotion—are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development.
    • Human Vaccines

      • 1st Edition
      • October 14, 2016
      • Kayvon Modjarrad + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 2 3 0 2 0
      • eBook
        9 7 8 0 1 2 8 0 2 5 4 2 0
      Human Vaccines: Emerging Technologies in Design and Development discusses the advances in molecular biology, biophysics, and informatics—among other disciplines—that have provided scientists with the tools to create new vaccines against emerging and re-emerging pathogens. For example, the virus-like particle technologies that led to licensing of highly efficacious HPV vaccines have only come into full realization in the last 10 years. Their success has, in turn, accelerated the pace with which nanoparticle vaccines are being developed Given the rapidity with which the field is changing and the absence of any text documenting this change, there is a need for a resource that surveys these new vaccine technologies, assesses their potential, and describes their applications. This book provides that resource and complements traditional vaccinology books, but also serves as an excellent standalone for researchers and students with basic knowledge in immunology.
    • The Evolution of the Immune System

      • 1st Edition
      • May 20, 2016
      • Davide Malagoli
      • English
      • Paperback
        9 7 8 0 1 2 8 0 1 9 7 5 7
      • eBook
        9 7 8 0 1 2 8 0 2 0 1 3 5
      The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors.
    • The Innate Immune Response to Noninfectious Stressors

      • 1st Edition
      • February 18, 2016
      • Massimo Amadori
      • English
      • Paperback
        9 7 8 0 1 2 8 0 1 9 6 8 9
      • eBook
        9 7 8 0 1 2 8 0 1 9 7 4 0
      The Innate Immune Response to Non-infectious Stressors: Human and Animal Models highlights fundamental mechanisms of stress response and important findings on how the immune system is affected, and in turn affects such a response. In addition, this book covers the crucial link between stress response and energy metabolism, prompts a re-appraisal of some crucial issues, and helps to define research priorities in this fascinating, somehow elusive field of investigation.
    • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

      • 1st Edition
      • April 8, 2016
      • M. A. Hayat
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 9 3 6 7
      • eBook
        9 7 8 0 1 2 8 0 2 9 5 1 0
      Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging: Volume 9: Human Diseases and Autophagosome offers a valuable guide to both cellular processes while helping researchers explore their potentially important connections. Volume 9 emphasizes the role of autophagy in diseases, such as leukemia, antifungal and antibacterial immunity, and transplantation. This volume also explains, in detail, the molecular mechanism(s) underlying the formation of autophagosomes, including the progression of omegasomes to autophagosomes. This information is important because one of the major functions of autophagy is to degrade and eliminate excessive, old, and harmful materials from the cell. Autophagosomes receive these materials (cellular cargo) and transport them to lysosomes for degradation. Lysosomes contain the digestive enzymes (hydrolases) that breakdown proteins, lipids, carbohydrates, etc. (self-digestion). To further explain this phenomenon, the role of the endoplasmic reticulum (ER) in the formation of autophagosomes is discussed. ULK1 and Beclin 1 proteins are also important in the initial formation of autophagosomes, and are also discussed. Because much of the early research in this area was carried out using yeast cells, the role of Golgi complex in the autophagosome formation in these cells is explained. This volume also includes an explanation of the role of the autophagy-related gene ATG5 in cancer (e.g., gastrointestinal cancer). Paradoxically, autophagy is a “double-edged sword” because it eliminates some pathogens, whereas it can be used by some intracellular pathogens to multiply and cause infection. This book is an asset to newcomers, providing a concise overview of the role of autophagy in necrosis and inflammation, while also serving as an excellent reference for more experienced scientists and clinicians.
    • Immunopotentiators in Modern Vaccines

      • 2nd Edition
      • November 2, 2016
      • Virgil E.J.C. Schijns + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 4 0 1 9 5
      • eBook
        9 7 8 0 1 2 8 0 4 0 9 5 9
      Immunopotentiators in Modern Vaccines, Second Edition, provides in-depth insights and overviews of the most successful adjuvants, those that have been included in licensed products, also covering the most promising technologies that have emerged in recent years. In contrast to existing books on the subject, the chapters here provide summaries of key data on the mechanisms of action of the individual vaccine adjuvants. In addition, the book covers key aspects of how the technologies might be further developed and what might be their limitations, while also giving an overview of what made the most advanced adjuvant technologies successful.
    • Immunotherapy of Cancer

      • 1st Edition
      • Volume 128
      • July 28, 2015
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 3 1 6 7
      • eBook
        9 7 8 0 1 2 8 0 2 5 5 4 3
      Immunotherapy of Cancer provides information on cancer research related to inflammation and immunity, containing outstanding reviews by experts in the field. It is suitable for researchers and students who have an interest in cancer immunobiology.
    • Advances in Immunology

      • 1st Edition
      • Volume 126
      • February 26, 2015
      • Frederick W. Alt
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 2 4 4 3
      • eBook
        9 7 8 0 1 2 8 0 2 4 3 2 4
      Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.
    • Advances in Immunology

      • 1st Edition
      • Volume 125
      • January 8, 2015
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 2 4 3 6
      • eBook
        9 7 8 0 1 2 8 0 2 4 3 1 7
      Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.