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Books in Clinical pharmacology therapeutics

1-10 of 28 results in All results

Quinone-Based Compounds in Drug Discovery

  • 1st Edition
  • November 1, 2024
  • Umar Ali Dar + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 2 4 1 2 6 - 0
  • eBook
    9 7 8 - 0 - 4 4 3 - 2 4 1 2 5 - 3
Quinone-Based Compounds in Drug Discovery: Trends and Applications provides a comprehensive and up-to-date overview of the latest advances in the field of drug discovery using quinone-based materials. The book covers various aspects of quinone-based materials such as their synthesis, characterization, and applications in drug discovery, consolidating current research. It introduces quinones in the pharmacology context and then describes current developments in drugs for key diseases and conditions. Final chapters deal with the regulatory and commercial framework to take quinone-based drugs to the market.This book will benefit a wide range of readers, including researchers, scientists, and graduate students in the field of drug discovery. Chemists and biochemists will also benefit from the contents of this book.

mRNA Therapeutics

  • 1st Edition
  • September 9, 2024
  • Anya Hillery
  • English
  • Paperback
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  • eBook
    9 7 8 - 0 - 4 4 3 - 2 8 9 3 5 - 4
mRNA Therapeutics: Foundations, Innovations, and Clinical Applications summarizes the scientific development of mRNA vaccines that have revolutionized the way we treat disease. This approach has the potential to treat a wide range of diseases, including COVID-19, cancer, and infectious diseases. The first section of the book introduces mRNA vaccines, including their history, mechanism of action, and potential applications. The second section delves into the science of mRNA vaccines, covering topics such as the structure of mRNA, the delivery of mRNA to cells, and the immune response to mRNA vaccines.The third section discusses the future of mRNA technology, exploring potential applications such as cancer therapy, prevention of infectious diseases, and replacement of missing or damaged proteins. This is a valuable resource for scientists, researchers, and clinicians who are interested in the latest developments in mRNA technology. It is also a useful reference for students and professionals who are working in the fields of biotechnology, pharmaceutical science, and vaccine development.

Therapeutic Drug Monitoring

  • 2nd Edition
  • April 26, 2024
  • Amitava Dasgupta
  • English
  • Hardback
    9 7 8 - 0 - 4 4 3 - 1 8 6 4 9 - 3
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 8 6 5 0 - 9
Therapeutic Drug Monitoring: Newer Drugs and Biomarkers, Second Edition is an updated reference on TDM analytical techniques in diverse clinical settings. This new edition reviews exciting new developments in the area, including seven new chapters covering immunoassay design and applications, combined chromatographic techniques in therapeutic monitoring, drug monitoring in alternative specimens, pharmacogenomics of anticancer drugs, pharmacogenomics testing for patient management, selected antifungal agents, pharmacodynamic monitoring, and therapeutic drug monitoring of selected anticoagulants. All remaining chapters in the first edition were thoroughly revised and updated.This book is the ideal reference for clinical pathologists, pharmacologists, and toxicologists involved with TDM. Scientists working in diagnostic companies, developing reagents for monitoring therapeutic drugs will also find relevant information in this book.

Pharmacogenomics

  • 1st Edition
  • June 13, 2023
  • Showkat Ahmad Ganie + 3 more
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 5 3 3 6 - 5
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 5 3 3 7 - 2
Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The book's chapters over the foundational aspects of pharmacogenomics, including drug metabolism, drug discovery, development, and testing, and then detail studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources. This is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. However, researchers and graduate students in the related fields of genetics, pharmacoepidemiology, molecular biology, and medicinal chemistry will also benefit from the structured approach of the book.

Standardizing Pharmacology: Assays and Hormones

  • 2nd Edition
  • February 23, 2023
  • Michael J. Parnham + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 8 5 5 1 7 - 4
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 5 5 1 8 - 1
Standardizing Pharmacology: Assays and Hormones, Volume Two in the Discoveries in Pharmacology series, presents selected articles from historic discoveries that are enhanced with commentary from contemporary scholars who present discussions on the importance of each chapter, along with an updated bibliography on the subject and contributions from a Nobel Prize winner and other pioneers in pharmacology. Academic and industry researchers in pharmacology and medicine, as well as advanced students will find this series a useful teaching tool and launch to new discoveries. Sections cover key discoveries in receptor theory, pharmacological methods and the development of hormone therapy, including J. Parascandola on the development of receptor theory, R.S. Yalow on radioimmunoassay, M. van Rossum and J.T L.A. Hurkmans on bioassays, M. Tausk on androgen therapy and C. Djerassi on oral contraceptives, with commentaries from experts such as T. Hökfelt and V.C. Jordan.

Lantibiotics as Alternative Therapeutics

  • 1st Edition
  • February 17, 2023
  • Sanket Joshi + 3 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 9 1 4 1 - 4
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 9 1 4 2 - 1
Lantibiotics as Alternative Therapeutics explores alternative therapeutics, lantibiotics and other novel drugs. This book provides concrete information to readers regarding lantibiotics and various types of antimicrobial peptides with their mode of actions in treating various multidrug resistant organisms. It explains various techniques that are involved in analyzing antimicrobial peptides and their mode of actions. The development of antibiotic resistance has now reached a point of crisis where innovative methods and application of novel compounds and methods are required to prevent the spread of drug resistant infections. Novel compounds exhibit different modes of action to the currently used mechanism of therapeutics in order to combat against the resistant organisms. Lantibiotics hold considerable potential as a consequence of their unusual structure, unique mechanisms of action and their potency against multi-drug resistant bacteria. This book will be useful for pharmaceutical industry scientists and researchers in microbial and biomedical research as well as graduate and advanced students in microbiology, medical biotechnology, health, and pharmaceutical sciences.

Recent Developments in Anti-Inflammatory Therapy

  • 1st Edition
  • February 17, 2023
  • Parteek Prasher + 4 more
  • English
  • Paperback
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  • eBook
    9 7 8 - 0 - 3 2 3 - 9 1 4 1 6 - 1
Advances in Anti-inflammatory Therapy explores the cutting-edge in anti-inflammation therapy in clear and concise language, with insights from academia and industry. Sections cover key regulatory pathways that mediate acute and chronic inflammation and disease onset. Further chapters are devoted to advanced anti-inflammatory pharmaceuticals, including chemical moieties, pharmacophores, APIs, natural products, herbal therapies, molecular nanomedicine and advanced drug delivery vectors. Systematically planned chapters and illustrations enable potential readers to gain essential insights on the most recent advancements in the field. Arranged with systematic chapters covering a broad range of inflammatory diseases, discussions on past, current and future therapeutics and advanced anti-inflammatory pharmaceuticals, this book will be useful to a wide range of researchers, especially medicinal chemists, drug design experts, and biological and translational researchers working in the field of inflammation.

Tamoxifen Tales

  • 1st Edition
  • January 12, 2022
  • V. Craig Jordan
  • English
  • Hardback
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  • Paperback
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  • eBook
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Tamoxifen Tales: Suggestions for Scientific Survival presents a case study describing the academic journey of teams behind major advances in medical sciences, highlighting lessons learned that are applicable to the next generation of scientists. This book provides a manual on the successful mentoring of young scientists, including stories describing how training experience shaped careers to become leaders in academia and the pharmaceutical industry. The book documents Professor V. Craig Jordan’s 50-year career in medical sciences that led to the discovery and development of Selective Estrogen Receptor Modulators (SERMs), which became the standard of women’s healthcare around the world. Additionally, it illustrates the versatility of a scientist with a commitment to serving societies. This important resource will be a useful and interesting book for established medical scientists, research mentors and advanced students wanting to chart a successful and impactful research career.

Atkinson's Principles of Clinical Pharmacology

  • 4th Edition
  • October 16, 2021
  • Shiew-Mei Huang + 3 more
  • English
  • Hardback
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  • eBook
    9 7 8 - 0 - 1 2 - 8 1 9 8 8 4 - 1
**Selected for Doody’s Core Titles® 2024 in Pharmacology**Atkinson’s Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology.

Clinical Pharmacology During Pregnancy

  • 2nd Edition
  • September 23, 2021
  • Donald Mattison + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 8 9 0 2 - 3
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 8 9 0 3 - 0
Clinical Pharmacology During Pregnancy, Second Edition is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals involved in the care of women during pregnancy. The book focuses on the impact of pregnancy on drug disposition and includes coverage of treatments for diseases of specific body systems as well as essential content on dosing and efficacy. This update includes substantially expanded sections on the ethics of pharmacological research in pregnancy and physiologic changes, along with new sections on patient reported outcomes in pregnancy, delivery and postnatal care, and the use of pharmacokinetic and pharmacodynamic approaches to estimate maternal, placental and fetal dosing. The broad range of this book encompasses analgesics, antiasthmatics, antidepressants, heart and circulatory drugs, vitamins and herbal supplements, and more. Topics in chemotherapy and substance abuse are also covered, as are research issues, including clinical trial design and ethical considerations.