Lantibiotics as Alternative Therapeutics
- 1st Edition - February 17, 2023
- Latest edition
- Editors: Sanket Joshi, Rajiv K. Kar, Dibyajit Lahiri, Moupriya Nag
- Language: English
Lantibiotics as Alternative Therapeutics explores alternative therapeutics, lantibiotics and other novel drugs. This book provides concrete information to readers regarding… Read more
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Description
Description
Lantibiotics as Alternative Therapeutics explores alternative therapeutics, lantibiotics and other novel drugs. This book provides concrete information to readers regarding lantibiotics and various types of antimicrobial peptides with their mode of actions in treating various multidrug resistant organisms. It explains various techniques that are involved in analyzing antimicrobial peptides and their mode of actions. The development of antibiotic resistance has now reached a point of crisis where innovative methods and application of novel compounds and methods are required to prevent the spread of drug resistant infections.
Novel compounds exhibit different modes of action to the currently used mechanism of therapeutics in order to combat against the resistant organisms. Lantibiotics hold considerable potential as a consequence of their unusual structure, unique mechanisms of action and their potency against multi-drug resistant bacteria. This book will be useful for pharmaceutical industry scientists and researchers in microbial and biomedical research as well as graduate and advanced students in microbiology, medical biotechnology, health, and pharmaceutical sciences.
Key features
Key features
- Includes the biology, molecular interaction with target molecule, putative genes and analytical techniques to isolate and identify compounds
- Incorporates relevant case studies to increase understanding
- Focuses on recent trends on novel antimicrobial agents and antibiotic resistance research
- Discusses new arena of diseases, apart from acute and chronic infections
Readership
Readership
Table of contents
Table of contents
2. Antimicrobial peptides and the potent mechanism of action
3. Lantibiotics and Gene regulation
4. Biosynthesis of Lantibiotics
5. Optimizations in the productions of Lantibiotics and Scale-Up
6. Analytical Techniques in Identifying & Purifying the proteins
7. Development of Recombinant Lantibiotics and their Potent Uses
8. Mechanism of Action of the Lantibiotics on the Multi-Drug Resistant Organism
9. Mechanism of inhibiting Biofilm associated Chronic Infections by Lantibiotics
10. Lantibiotics & Its Role in Food Preservation
11. In-Silico studies of the Interaction of Lantibiotics with Virulent Proteins
12. Insights at the atomistic resolution of Lantibiotics using Multiscale Simulations
13. Case studies: Applications of such novel drugs
14. Recent updates in understanding of molecular genetics of lantibiotics production
15. In silico molecular modelling approach for better designing and applications
16. Marine microbes as a potential source of novel drugs
17. Combinations of nano-bio molecules as next generation antimicrobial agents
Product details
Product details
- Edition: 1
- Latest edition
- Published: February 17, 2023
- Language: English
About the editors
About the editors
SJ
Sanket Joshi
RK
Rajiv K. Kar
DL
Dibyajit Lahiri
Dr. Dibyajit Lahiri is an Associate Professor in the Department of Biotechnology at the University of Engineering & Management, Kolkata, India, where he conducts advanced interdisciplinary research in microbiology, biofilms, antimicrobial resistance, and microbial biotechnology. His scholarly work emphasizes understanding the mechanisms of microbial biofilm formation and inhibition, particularly on medically relevant surfaces and environmental substrates, and exploring innovative strategies for combating biofilm-associated antimicrobial resistance.
Dr. Lahiri has authored and co-authored a substantial body of scholarly work, with over 100 publications including high-impact journal articles, book chapters, and reviews. His research portfolio covers topics such as biofilm-mediated degradation of environmental pollutants, novel antibiofilm agents (including nanoscale and natural compounds), and biotechnological applications of microbial systems, with an h-index around 38 reflecting significant citation impact and academic influence.
He has contributed to major scientific discussions on microbial biofilms in diverse contexts, including their roles in chronic infections, environmental microplastic degradation, and biofuel production, demonstrating both fundamental and applied research orientations. His collaborative research outputs also include contributions to antimicrobial peptide studies and microbial electrochemical systems.
Dr. Lahiri serves as editor and contributor to scholarly publications in his field, and he participates actively in international research networks and editorial activities. His work is regularly presented at scientific forums and continually contributes to advancing microbial biotechnology and strategies to mitigate biofilm-associated challenges in health, industry, and the environment.MN
Moupriya Nag
Moupriya Nag is presently working as Associate Professor in the Department of Biotechnology, University of Engineering & Management, Kolkata. Her research interests includes single molecule Biophysics of protein unfolding/refolding and protein aggregation kinetics and its mechanism of action especially the amyloid proteins in neurodegenerative disorders. Recently, her research focuses on functional amyloids in bacteria and their relation in forming biofilms. Her work deals with developing novel antimicrobial and anti-biofilm compounds from natural sources including plants, microbes and green synthesized nanoparticles. She has about seven years of teaching experience in Biophysics, Bioinformatics, Bioprocess and Biotechnology, Enzyme Technology, Computing, Molecular Modelling and Drug Design. She has also published many research articles in the peer-reviewed international journals and authored/edited or co-authored/edited numerous books/book chapters. She is also a member of many scientific societies like Indian Biophysical Society and Indian Science Congress Association.