Lantibiotics as Alternative Therapeutics
- 1st Edition - February 17, 2023
- Latest edition
- Editors: Sanket Joshi, Rajiv K. Kar, Dibyajit Lahiri, Moupriya Nag
- Language: English
Lantibiotics as Alternative Therapeutics explores alternative therapeutics, lantibiotics and other novel drugs. This book provides concrete information to readers regarding… Read more
Description
Description
Lantibiotics as Alternative Therapeutics explores alternative therapeutics, lantibiotics and other novel drugs. This book provides concrete information to readers regarding lantibiotics and various types of antimicrobial peptides with their mode of actions in treating various multidrug resistant organisms. It explains various techniques that are involved in analyzing antimicrobial peptides and their mode of actions. The development of antibiotic resistance has now reached a point of crisis where innovative methods and application of novel compounds and methods are required to prevent the spread of drug resistant infections.
Novel compounds exhibit different modes of action to the currently used mechanism of therapeutics in order to combat against the resistant organisms. Lantibiotics hold considerable potential as a consequence of their unusual structure, unique mechanisms of action and their potency against multi-drug resistant bacteria. This book will be useful for pharmaceutical industry scientists and researchers in microbial and biomedical research as well as graduate and advanced students in microbiology, medical biotechnology, health, and pharmaceutical sciences.
Key features
Key features
- Includes the biology, molecular interaction with target molecule, putative genes and analytical techniques to isolate and identify compounds
- Incorporates relevant case studies to increase understanding
- Focuses on recent trends on novel antimicrobial agents and antibiotic resistance research
- Discusses new arena of diseases, apart from acute and chronic infections
Readership
Readership
Table of contents
Table of contents
2. Antimicrobial peptides and the potent mechanism of action
3. Lantibiotics and Gene regulation
4. Biosynthesis of Lantibiotics
5. Optimizations in the productions of Lantibiotics and Scale-Up
6. Analytical Techniques in Identifying & Purifying the proteins
7. Development of Recombinant Lantibiotics and their Potent Uses
8. Mechanism of Action of the Lantibiotics on the Multi-Drug Resistant Organism
9. Mechanism of inhibiting Biofilm associated Chronic Infections by Lantibiotics
10. Lantibiotics & Its Role in Food Preservation
11. In-Silico studies of the Interaction of Lantibiotics with Virulent Proteins
12. Insights at the atomistic resolution of Lantibiotics using Multiscale Simulations
13. Case studies: Applications of such novel drugs
14. Recent updates in understanding of molecular genetics of lantibiotics production
15. In silico molecular modelling approach for better designing and applications
16. Marine microbes as a potential source of novel drugs
17. Combinations of nano-bio molecules as next generation antimicrobial agents
Product details
Product details
- Edition: 1
- Latest edition
- Published: February 17, 2023
- Language: English
About the editors
About the editors
SJ
Sanket Joshi
RK
Rajiv K. Kar
DL
Dibyajit Lahiri
Dibyajit Lahiri, PhD, is Associate Professor in the Department of Biotechnology, University of Engineering & Management, Kolkata. His research focuses on biofilm formation on human prostheses and its inhibition through phytochemical and nanocompound interventions, with particular interest in the molecular mechanisms by which natural compounds disrupt biofilm integrity. His work also encompasses computational drug development using bioinformatics approaches. Dr. Lahiri has authored over 100 publications, has edited academic volumes in his field, and serves as Associate Editor for multiple international peer-reviewed journals.
MN
Moupriya Nag
Moupriya Nag, PhD, is an Associate Professor in the Department of Biotechnology at UEM, Kolkata. Her research interests include single molecule biophysics, particularly protein unfolding/refolding and protein aggregation kinetics. She has expertise in biophysical chemistry, photochemistry, and single molecule spectroscopy, and has worked on protein-ligand interactions and in-vitro detection of metal ions. Her postdoctoral work explored peptide aggregation kinetics related to neurodegenerative diseases. Currently, her research focuses on functional amyloids in bacteria and their role in biofilm formation.