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Elsevier

Saunders

  • Advances in Melanoma, An Issue of Hematology/Oncology Clinics

    • 1st Edition
    • Volume 23-3
    • David E. Fisher
    • English
    The field of melanoma biology has experienced a remarkable surge in recent years, owing to progress which has ranged from the most basic laboratory/preclinic... discoveries to clinical developments that have begun to transform the management and prognosis for at least certain melanoma patients. Among the key areas that have contributed to this progress are studies relating to signaling and transcriptional pathways that regulate control over differentiation and survival of the melanocyte lineage. The identification of recurring activating mutations in specific signaling factors (B-RAF, N-Ras, c-KIT), amplification of other melanoma oncogenes (MITF, NEDD9), and the crucial recognition that certain of these genomic events occur within melanomas arising with specific clinical features (eg mucosal or acral origin) have led to clear recognition that melanoma is indeed “many different diseases.” While the various subclasses of melanoma may share common features, such as profound invasive and metastatic propensity, it is also likely that sharply focused therapeutic strategies may exploit the functionally critical molecular engines, which distinguish these subclasses. Certain strategies focus upon the immunogenicity and striking clinical opportunities afforded by immune modulation, while others focus more directly on tumor-specific targeting. This issue brings together some of the leaders who have contributed significant insights from basic melanoma biology to progress in the clinic.

  • Skin Surgery and Minor Procedures, An Issue of Surgical Clinics

    • 1st Edition
    • Volume 89-3
    • Frederick Radke
    • English
    Melanoma; Pressure Ulcers; Wound Healing and Biology of the Skin; Local anesthetics-uses and toxicities; Approach to excision and closure of the skin; Unusual Skin Tumors; Dermatologic considerations for the General Surgeon; Suture choice and other skin closure methods; Benign and subcutaneous lesions; Common skin cancers and their precursors; Pilonidal cyst and benign perianal skin conditions

  • Arthritis and Arthroplasty: The Hip

    Expert Consult - Online, Print and DVD
    • 1st Edition
    • Thomas E. Brown + 3 more
    • English
    The Hip—a volume in the new Arthritis and Arthroplasty series—offers expert guidance on everything from patient selection and pre-operative planning to surgical approaches and techniques. Clear, evidence-based coverage details which technology and methodology used for total Hip arthroplasty (THA), reconstruction or revision is best for each patient. Access discussions of debates on minimally invasive surgery; component material and bearing options; cemented vs. uncemented fixation of the components; and more. Explore alternatives to THA in younger arthritic patients and view expertly narrated video demonstrations of surgical techniques. In addition to providing practical, pragmatic advice in a concise, readable format, this Expert Consult title offers the full text of the book, as well as links to PubMed and periodic content updates, online at expertconsult.com.

  • Cancer Emergencies, Part 1, An Issue of Emergency Medicine Clinics

    • 1st Edition
    • Volume 27-2
    • Mohamud Daya + 1 more
    • English
    First of a two-part issue dealing with Cancer Emergencies by Drs. Mohamud Daya and Charles Thomas. Topics with include: "Spinal Cord Compression," "Cerebral Edema," "Acute Renal Failure," "Electrolyte Disorders," and more!

  • Key Consultations in Hepatology, An Issue of Clinics in Liver Disease

    • 1st Edition
    • Volume 13-2
    • Paul Martin
    • English
    Often the hepatologist sees patients in consultation, and this issue focuses on how to deal with diagnosing, treating, and managing patients in the hospital on a consultation basis. The Guest Editor has assembled top experts to present articles on the asymptomatic outpatient with abnormal LFTs, surgery in the patient with liver disease, issues in long-term care of liver transplant recipients, management of autoimmune cholestatic liver disease, and current status of hepatitis vaccination and prophylaxis, to name a few.

  • The High-Risk Neonate: Part II, An Issue of Critical Care Nursing Clinics

    • 1st Edition
    • Volume 21-2
    • M. Terese Verklan
    • English
    In the last issue of a two-part series devoted entirely to neonatal critical care nursing (also Guest Edited by Terese Verklan), topics include Retinopathy of Prematurity, the Near-Term Infant, endocrine issues including congenital adrenal hyperplasia and ambiguous genitalia, nutrition in the 1000g neonate, safety issues and issues of informed consent in the NICU, substance abuse, pain, ethics, and grieving and removal of life support from the parent's perspective.

  • Interventional Head and Neck Imaging, An Issue of Neuroimaging Clinics

    • 1st Edition
    • Volume 19-2
    • Dheeraj Gandhi
    • English
    Interventional Neuroradiology is a minimally invasive approach in the treatment of vascular diseases of the central nervous system. This exciting new issue of Neuroimaging Clinics, Guest Edited by Dheeraj Gandhi, includes such topics as: CT guided percutanous biopsies of the head and neck Dangerous collaterals in the head and neck Treatment of carotid-cavernous fistulae This issue is a must-have clinical resource.

  • Hypertensive Disease: Current Challenges, New Concepts, and Management, An Issue of Medical Clinics

    • 1st Edition
    • Volume 93-3
    • Edward D. Frohlich
    • English
    This issue of the Medical Clinics of North America brings the practicing clinician up to date on the current challenges, new concepts, and management of hypertensive disease. Topics covered include risks in hypertension; new biological concepts of target organ involvement in hypertension; hypertension and the metabolic syndrome; aging versus hypertension; hypertension, systolic blood pressure, and large arteries; oxidative stress, endothelial dysfunction, and hypertension; current thinking about hypertensive heart disease; diastolic dysfunction as a link between hypertension and heart failure; hypertension and cardiac failure in its various forms; hypertension and atherogenesis; the kidney, hypertension, and remaining challenges; current thinking about renovascular hypertension; obesity and hypertension; and barriers to adherence in hypertension management.

  • Enhanced Endoscopic Imaging, An Issue of Gastrointestinal Endoscopy Clinics

    • 1st Edition
    • Volume 19-2
    • Grace Elta + 1 more
    • English
    Endoscopic imaging has become an important clinical tool for the diagnosis and treatment of gastrointestinal diseases and is poised to advance in a revolutionary fashion in the next few years. The articles in this issue are a result of an ASGE Imaging workshop held in early 2008. The goal of the workshop, and this issue, is to bring together clinical investigators and biophotonics engineers to help develop and clinically apply enhanced imaging technologies for the eventual benefit of patients. Articles in this issue are devoted to chromoendoscopy, autofluorescence endoscopy, reflectance spectroscopy, optical coherence tomography, laser confocal microscopy, and targeted endoscopic imaging to name a few.

  • Education, An Issue of Perioperative Nursing Clinics

    • 1st Edition
    • Volume 4-2
    • Jane C. Rothrock
    • English
    To provide a safe environment, perioperative nurses need to have a broad knowledge of surgical anatomy, physiological alterations and risk factors. Employment of Perioperative Nurses is increasing with the demand for more healthcare and the educational needs for the novice nurse are growing. This new issue of Clinics in Perioperative Nursing focuses on Education and is Guest Edited by Jane Rothrock, an expert in the field. Some topics that are explored include: Using simulation to teach undergraduate nursing students, Educating novice perioperative nurses, and Diversity in education.

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