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    • Obesity Management, An Issue of Primary Care Clinics in Office Practice

      • 1st Edition
      • Volume 36-2
      • June 26, 2009
      • Vanessa Diaz + 1 more
      • English
      • Hardback
        9 7 8 1 4 3 7 7 0 5 3 3 1
      The prevalence of obesity has increased markedly in recent years, and obesity is now considered an epidemic in the US. Obesity and its related metabolic abnormalities contribute significantly to cardiovascular disease, and excess weight is a risk factor for multiple disease outcomes, including cancer. The purpose of this issue is to heighten the awareness of primary care physicians regarding the obesity epidemic and its long-term effects on health and on minorities and children, and to present prevention strategies and interventions.

    • Pediatric and Adolescent Gynecology, An Issue of Obstetrics and Gynecology Clinics

      • 1st Edition
      • Volume 36-1
      • April 22, 2009
      • S. Paige Hertweck
      • English
      • Hardback
        9 7 8 1 4 3 7 7 0 5 1 0 2
      Pediatric and Adolescent Gynecology is reviewed in this issue of Obstetrics and Gynecology Clinics, guest edited by Dr. S. Paige Hertweck. Authorities in the field have come together to pen articles on Genital Trauma, Urologic Issues, Endometriosis in the Adolescent, Adolescent STIs, Intersex Disorders, Mullerian Anomalies, Polycystic Ovarian Syndrome in the Adolescent, Bleeding Disorders in Adolescents, Thrombophilial Conditions in the Adolescent, Adolescent Contraception, Management of Abnormal Cervical Cytology in the Adolescent, and Premature Ovarian Failure/Turner Syndrome in the Adolescent.

    • Biliary Tract Cancers, An Issue of Surgical Oncology Clinics

      • 1st Edition
      • Volume 18-2
      • April 22, 2009
      • Joseph J. Bennett
      • English
      • Hardback
        9 7 8 1 4 3 7 7 0 9 1 2 4
      Proposed topics for this issue include: Malignant Masquerade: Dilemmas in Diagnosing Biliary Obstruction; Molecular Mechanisms of Cholangiocarcinogene... Multimodality Imaging of Biliary Malignancies; Percutaneous Approach to the Diagnosis and Treatment of Biliary Tract Malignancies; Portal Vein Embolization in Hilar Cholangiocarcinoma; Extrahepatic Cholangiocarcinoma: Current surgical strategy; Management and Extent of Resection for Intrahepatic Cholangiocarcinoma; Surgical Management of Gallbladder Cancer; Transplantation for Cholangiocarcinoma: When and for Whom?; Radical Resection of Biliary Tract Cancers and the Role of Extended Lymphadenectomy; Indications for neoadjuvant, adjuvant and palliative chemotherapy in the treatment of biliary tract cancers.

    • Equine Internal Medicine

      • 3rd Edition
      • December 10, 2009
      • Stephen M. Reed + 2 more
      • English
      • eBook
        9 7 8 1 4 3 7 7 0 8 8 5 1
      Develop an essential understanding of the principles of equine disease with this one-of-a-kind, problem-based resource! Extensively revised and updated with contributions from an international team of experts, Equine Internal Medicine, 3rd Edition reflects the latest clinical research in equine medicine and focuses on the basic pathophysiologic mechanisms that underlie the development of various equine diseases to help you confidently diagnose, treat, and manage patient conditions.

    • Consultations in Feline Internal Medicine, Volume 6

      • 1st Edition
      • November 3, 2009
      • John R. August
      • English
      • eBook
        9 7 8 1 4 3 7 7 0 1 8 8 3
      Completely revised and updated with 80 all-new chapters covering the most important information on current diagnostic, treatment, and preventive challenges facing feline practitioners today, Consultations in Feline Internal Medicine is an invaluable addition to every small animal clinician’s library. Full-color illustrations and expert contributions help you master and apply the latest advances in feline nutrition, emerging diseases, pet overpopulation, advanced imaging, and more with a comprehensive, clinically relevant approach.

    • Autoimmune Endocrine Disorders, An Issue of Endocrinology and Metabolism Clinics of North America

      • 1st Edition
      • Volume 38-2
      • April 23, 2009
      • Simon H.S. Pearce
      • English
      • Hardback
        9 7 8 1 4 3 7 7 0 4 7 1 6
      Autoimmune disorders are amongst the most frequently encountered conditions in endocrine practice. The evidence-based approach to therapeutics and detailed evaluation of the outcome of existing treatment regimens have led to some advances in care delivery. Pragmatic reviews by leading international experts outline the clinical state of the art in several chapters of this issue of the Endocrinology and Metabolism Clinics of North America devoted to autoimmune disorders. Topics covered include the following: regulatory T cells as key players in tolerance and autoimmunity; immunology lessons from monogenic conditions such as AIRE; immunogenetics of T1D and AITD; advances in T1D therapeutics, including islet cell replacement and salvage; updates on TSHR structure, function, and monoclonal human TSHR antibodies; animal models of Grave’s disease; evidence-based and emerging modalities of treatment of Graves’ hyperthyroidism; patient selection and treatment of thyroid-associated ophthalmopathy; antibodies to steroidogenic tissues: Addison’s and POF; diagnosis and management of polyendocrinopathy syndromes; autoimmune parathyroid disease; and autoimmune hypophysitis.

    • Proteomics in Laboratory Medicine, An Issue of Clinics in Laboratory Medicine

      • 1st Edition
      • Volume 29-1
      • May 26, 2009
      • Emanuel F. Petricoin
      • English
      • Hardback
        9 7 8 1 4 3 7 7 0 4 9 3 8
      Topics include: Development and Validation of Reverse Phase Protein Microarrays for Personalized Therapy, Imaging Mass Spectrometry for Predictive and Prognostic Medicine, Immunomic Based Profiling for Early Cancer Detection, Antibody Arrays for Clinical Applications, Autoantibody profiling for Cancer Detection, Development and validation of a protein based signature for ovarian cancer detection, Analytical considerations for Mass Spectrometry Profiling in Serum Biomarker Discovery, Salivary Biomarkers for Clinical Applications, Proteomics of Caveolea: Clinical Applications, Clinical opportunities for renal cell cancer management using proteomics, Cardiovascular Proteomics: implications for clinical applications, Clinical Proteomic Applications from FFPE, Development of high throughput mass spectrometry- based approaches for cancer biomarker discovery and implementation, Proteomics and Diabetic Retinopathy.

    • Sepsis, An Issue of Critical Care Clinics

      • 1st Edition
      • Volume 25-4
      • December 1, 2009
      • R. Phillip Dellinger
      • English
      • Hardback
        9 7 8 1 4 3 7 7 1 2 0 4 9
      Respected leader in Critical Care Medicine, Phillip Dellinger has complied a top-notch range of articles on the subject of Sepsis. Topics include: "The History of Sepsis," "Molecular Biology of Sepsis," "Sepsis Induced Tissue Hypoperfusion," "Hemodynamic Monitoring in Sepsis," "Performance Improvement in Sepsis," and more!

    • Complications in Cosmetic Facial Surgery, An Issue of Oral and Maxillofacial Surgery Clinics

      • 1st Edition
      • Volume 21-1
      • March 2, 2009
      • Joe Niamtu
      • English
      • Hardback
        9 7 8 1 4 3 7 7 0 5 1 2 6
      Guest Editor Joseph Niamtu III presents a comprehensive look at cosmetic facial surgery complications for the oral and maxillofacial surgeon. The issue will cover complications in facelifts, skin resurfacing, botox and fillers, facial implants, blepharoplasty, rhinoplasty, fat injections, hair transplantation, and otoplasty. Other articles cover nerve injuries and treatment, and legal issues.

    • Advances in Melanoma, An Issue of Hematology/Oncology Clinics

      • 1st Edition
      • Volume 23-3
      • June 18, 2009
      • David E. Fisher
      • English
      • Hardback
        9 7 8 1 4 3 7 7 0 4 8 8 4
      The field of melanoma biology has experienced a remarkable surge in recent years, owing to progress which has ranged from the most basic laboratory/preclinic... discoveries to clinical developments that have begun to transform the management and prognosis for at least certain melanoma patients. Among the key areas that have contributed to this progress are studies relating to signaling and transcriptional pathways that regulate control over differentiation and survival of the melanocyte lineage. The identification of recurring activating mutations in specific signaling factors (B-RAF, N-Ras, c-KIT), amplification of other melanoma oncogenes (MITF, NEDD9), and the crucial recognition that certain of these genomic events occur within melanomas arising with specific clinical features (eg mucosal or acral origin) have led to clear recognition that melanoma is indeed “many different diseases.” While the various subclasses of melanoma may share common features, such as profound invasive and metastatic propensity, it is also likely that sharply focused therapeutic strategies may exploit the functionally critical molecular engines, which distinguish these subclasses. Certain strategies focus upon the immunogenicity and striking clinical opportunities afforded by immune modulation, while others focus more directly on tumor-specific targeting. This issue brings together some of the leaders who have contributed significant insights from basic melanoma biology to progress in the clinic.

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