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Elsevier Science

Environmental Statistics
1st Edition
Volume 12
G.P. Patil
English
The question of what environmental statistics is about is particularly important when it comes to the formulation of relevant research and training, whether in academia, agencies, or industries. This volume aims to give a new perception on the subject with some examples that are of concern and interest today. Environmental statistics is in a take-off stage both for reasons of societal challenge and statistical opportunity, and is demanding more and more from non-traditional and innovative statistical approaches. The chapters in this volume, which are specially prepared by several outstanding professionals involved in statistics and the environment, discuss the current state of the art in diverse areas of environmental statistics. The volume provides new perspectives and problems for future research, training, policy and regulation. It will be valuable to researchers, teachers, consultants and graduate students in statistics, environmental statistics, statistical ecology, and quantitative environmental sciences in academia, industries, governmental agencies, laboratories and libraries.
Bacterial Cell Wall
1st Edition
Volume 27
J.-M. Ghuysen + 1 more
English
Studies of the bacterial cell wall emerged as a new field of research in the early 1950s, and has flourished in a multitude of directions. This excellent book provides an integrated collection of contributions forming a fundamental reference for researchers and of general use to teachers, advanced students in the life sciences, and all scientists in bacterial cell wall research.Chapters include topics such as: Peptidoglycan, an essential constituent of bacterial endospores; Teichoic and teichuronic acids, lipoteichoic acids, lipoglycans, neural complex polysaccharides and several specialized proteins are frequently unique wall-associated components of Gram-positive bacteria; Bacterial cells evolving signal transduction pathways; Underlying mechanisms of bacterial resistance to antibiotics.
Free Radical Damage and its Control
1st Edition
Volume 28
C.A. Rice-Evans + 1 more
English
This book provides a comprehensive treatise on the chemical and biochemical consequences of damaging free radical reactions, the implications for the pathogenesis of disease and how this might be controlled endogenously and by radical scavenging drugs. Oxidative stress may be influenced by exogenous agents of oxidative stress, radiation, trauma, drug activation, oxygen excess, or by exogenous oxidative stress which is associated with many pathological states including chronic inflammatory disorders, cardiovascular disease, injury to the central nervous system, and connective tissue damage. This and many other such aspects are presented clearly and in depth.The development of antioxidant drugs depends on the understanding of the mechanisms underlying the generation of excessive free radicals in vivo, the factors controlling their release and the site of their action. This excellent volume presents an up-to-date account of the current state of knowledge in these areas.
Diagenesis, IV
1st Edition
Volume 51
G.V. Chilingarian + 1 more
English
The present volume continues the philosophy of gathering contributions on diagenesis on behalf of those requiring such periodic literary surveys, namely, academics and practitioners (teachers, researchers, and oil and ore explorationists).
Flow and Rheology in Polymer Composites Manufacturing
1st Edition
Volume 10
S.G. Advani
English
This book is aimed at scientists and practicing engineers who are currently exploring or would like to explore the complexity of fabrication processes of polymer composites. It deals with the mechanics and modeling aspects of discontinuous and continuous fiber composites and familarizes the engineer with the critical and fundamental issues of material processing and transport phenomena in polymeric composites and their applications in modeling and simulating specific composite manufacturing processes.Divided into three parts, Part A deals with the deformation science or rheology of these filled materials. It clearly shows the need to characterize their flow behavior before one can draw any conclusions about its processibility during manufacturing. Part B focuses on development of constitutive equations to describe the flow and deformation behavior of such materials under external processing conditions. Part C discusses the mathematical models for selected composite processes and their implementation into a computer simulation to analyze the process behavior. The processes represented in Part C cover a cross-section of important manufacturing processes and maintain a balance between processes that use short fibers and continuous fibrous materials.
Biological Function of Gangliosides
1st Edition
Volume 101
L. Svennerholm + 6 more
English
This book focuses on the role of gangliosides in three areas of medicine in which rapid progress has been made in the last decade: cancer, peripheral neuropathies and Alzheimer's disease. The volume further reflects progress in the pathogenesis of peripheral neuropathies, and the controversial role of gangliosides, also in therapeutic administration. There is a section on the role of gangliosides in neuronal differentiation and development and their receptor functions and cell surface activities. This excellent addition to the renowned Progress in Brain Research series also contains an invaluable plenary lecture on molecular basis of cell adhesion by Nobel prizewinner Gerald Edelman.
European Isolation and Confinement Study
1st Edition
Volume 3
S.L. Bonting
English
This third volume in the series, Advances in Space Biology and Medicine, is a special volume dedicated entirely to the results of the first European study of the effects of long-term confinement and isolation. The project was sponsored by the European Space Agency's Long-Term Program Office, Directorate of Space Station and microgravity, in preparation for its long-term manned space missions, the first of which will be its participation in Space Station Freedom through the Columbus program.The project was called the Isolation Study for European Manned Space Infrastructures, abbreviated ISEMSI. It was executed in the hyperbaric chamber facility of the Norwegian Underwater Technology Center (NUTEC), Bergen, Norway in September/October 1990. Six carefully selected men, called the EMSInauts, were confined in the chamber for a period of 28 days. The isolation period was preceded by a training period of two weeks, the pre-isolation period, during which baseline data on the subjects were obtained. It was followed by a recovery period, the post-isolation period, during which further tests were performed outside the chamber.The primary aim of ISEMSI was to obtain information on the psychological and physiological effects of long-term isolation and confinement of a small crew group under conditions similar to those that may be expected to exist for a space station crew. The simulation was designed to be as realistic as possible, except for the absence of weightlessness. This implied that the EMSInauts were given a considerable workload of tasks to be performed each day of the experimental period. The workload consisted of questionnaires and tests of a psychological and physiological nature, of housekeeping duties, and of additional space-related experiments. The nature and the results of their activities are described in thirteen chapters of this volume. In addition there is an introductory chapter by the head of the Long-Term Program Office, ESA, and chapters about Russian and American isolation studies of a similar nature.Together this material should offer the reader a rather comprehensive view of the psychophysiological aspects of the confinement and isolation inherent in long-term space missions; missions which may be expected to become common-place in decades ahead. The list of contents indicates the wide range of topics studied: group functioning and communication; spatial behavior; workload and stress; mental performance; cognitive fatigue; attention; sleep quality; and physiological aspects, such as water and salt turnover, cardiac function, hormones and electrolytes, orthostatic function, and immune function. The additional experiments cover important topics such as telemedical treatment, telescience, and microbial and chemical contamination monitoring.The results of this study and further studies of this nature should not only benefit future astronauts and help those who are organizing long-term manned space missions, but should also be useful to investigators who are planning crew-operated experiments to be carried out during such missions.
Studies in Abnormal Pressures
1st Edition
Volume 38
W.H. Fertl + 2 more
English
When Fertl's first book, Abnormal Formation Pressures, was published by Elsevier in 1976, the topic was relatively new in book form. In the years that followed, his book became the standard work for petroleum engineers and drillers. The list of major petroleum provinces with abnormally high pore pressures has grown steadily over the years, and with it has grown our knowledge and experience. There have also been technological advances. A new book was required, but no longer could the topic be covered adequately by one person. The problems of abnormally high formation pressures encountered in the subsurface while drilling for petroleum are very diverse, involving geologists, geophysicists, reservoir engineers, drilling engineers, and borehole logging engineers. The acute anticipation of such pressures before drilling has become possible with modern technology. This book treats these developments and covers the following topics: world occurrences, the geology of abnormal pore pressures and the background theory, reservoir engineering aspects of abnormally pressured reservoirs, detection of abnormal pressures by geophysical methods before drilling and during drilling, and their evaluation after drilling. It examines the special problems of shallow hazards from shallow abnormal pressures, and relief-well engineering to control blowouts. It also examines the generation of abnormal pressures from hydrocarbon generation in the Rocky Mountains, and the distribution of abnormal pressures in south Louisiana, USA. The topics are examined from a practical point of view with a theoretical background. There is a glossary of terms, and a relevant practical conversion table. Both SI units and the conventional US oil industry units are used.
Membrane Traffic in Protozoa, Part A
1st Edition
Volume 2
H. Plattner
English
Membranes are highly dynamic and operate not only as inert boundaries, but the packages they carry around in a cell are well addressed fro appropriate delivery. This holds for a variety of endomembrane systems engaged in exo- and endocytosis, for organelles along the biosynthetic pathway, phagosomes, and lysosomes. It also holds for the establishment of functional surface properties. Cell pairing (conjugation) phenomena are a good model for the problem of how a cell can discriminate between "self" and "non-self". On the other hand parasitic sporozoa developed to experts in masking their molecular sur-"face"by frequent shedding of their variant antigens. The discovery of their glycosyl-phosphatidy... (GPI) anchor has led to the discovery, in polar epithelial cells, of a specific targeting mechanism for GPI-anchored surface glycoproteins. Over one hundred such proteins have been detected in metazoans since then.Many of these basic aspects are dealt with in this book using quite different methodical approaches. Of course, there are many more aspects previously known from metazoan systems and such aspects then had to be verified also for Protozoa systems and such aspects then had to be verified also for protozoa. In this context, it is fascinating to see how basic cellular functions are maintained - with variations of the basic theme - throughout evolution.However, sometimes cell biologists dedicated to work with protozoa have to live with a regrettable phenomenon. Colleagues working with "higher" eukaryotic cells are frequently unaware of the fact that the primary input may have come from work with protozoa. Some phenomena may even be rediscovered inadvertently. In this sense, this book should address not only colleagues working with protozoa but also many of our fellow cell biologists working with metazoan cells.
Morbid Anatomy of the Genome
1st Edition
Volume 2
R.S. Verma
English
The technical advances in molecular biology have endowed us with a wealth of knowledge, which has allowed us to identify the cause of diseases not only at a single gene level but at a greater magnitude, where a substitution or deletion of a single base pair can be identified. Our present task is to establish a clear link between phenotype and nucleotide sequence. Obviously, a gene is no longer an imaginary entity. Recent discoveries in a number of bewildering traits, whose inheritance do not follow simple mendelian rules, have caused much amazement. For example, fragile X-syndrome, spine and bulbar muscular atrophy and myotic dystrophy arise from "triples repeat mutation" and amplification in future generations. Genetic diseases which are inherited, can now be diagnosed prenatally; an idea that was once inconceivable.The aim of the second volume, entitled Morbid Anatomy of the Genome, is to reflect on the importance of molecular genetics in modern medicine. The field has expanded so as to warrant a volume dedicated exclusively toward understanding those who wish to know the cause, detection and in turn treatment of such diseases. In this volume, I have commissioned several scientists to contribute 12 chapters. A chapter describing a special role of molecular genetics in combating genetic diseases through gene therapy has also been included, while chapter 13 is a commentary.A complete account of all diseases whose genetic basis is well established would be a herculean task and is not within the scope of a single volume format. Therefore a few specific topics have been chosen which may be of the greatest interest to scientists and clinicians. The purpose of this issue is to keep abreast of the latest developments in a select group of genetic diseases.

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