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Elsevier

Elsevier Science

  • Telomerase, Aging and Disease

    • 1st Edition
    • Volume 8
    • M.P. Mattson
    • English
    This volume of Advances in Cell Aging and Gerontology critically reviews the rapidly advancing area of telomerase research with a focus at the molecular and cellular levels. The clearly established function of telomerase is to maintain chromosome ends during successive rounds of cell division by adding a six base DNA repeat on to the telomeric ends of chromosomes. As presented in the chapters of this volume, the mechanisms that regulate telomerase expression and activity are complex. Moreover, emerging data suggest additional roles for telomerase in the regulation of cell differentiation and survival.It is expected that this quite comprehensive volume will provide a valuable resource for graduate students and postdocs in the telomerase field and for established investigators in other fields who are beginning to study telomerase in their particular research program. With an increasing number of proteins being brought into the fold of telomerase research (e.g., DNA damage and repair response proteins, heat-shock proteins, and proteins in various signal transduction cascades) many new scientists are beginning to study this enzyme from novel vantage points.

  • Ecological and Silvicultural Strategies for Sustainable Forest Management

    • 1st Edition
    • T. Fujimori
    • English
    Recognizing the increased interest in forest management world wide, this book addresses the current knowledge gap by defining sustainable forest management, clarifying methods by which ecological knowledge can be applied and how traditional silvicultural methods can be improved. Sustainable forest management involves the enhancement of various aspects of forest functions such as conservation of biodiversity, conservation of soil and water resources, contribution to the global carbon cycle as well as wood production. To establish ecological and silvicultural theories to enhance these functions harmoniously, recognizing the relationship between stand structures and their functions is essential. This volume presents target stand structures for aimed forest functions in relation to stand development stages, as well as ecological and silvicultural methods to lead and maintain them. Ecological and silvicultural strategies are discussed, both on stand and landscape levels, and from local to international levels in temperate and boreal forest zones.

  • Chitin: Fulfilling a Biomaterials Promise

    • 1st Edition
    • Eugene Khor
    • English
    So far little has been discussed on the groundwork necessary for chitin to claim its rightful place as a biomaterial. This book aims to describe the factors necessary to standardize chitin processing and characterization. It attempts to capture the essential interplay between chitin's assets and its limitations as a biomaterial, placing the past promises of chitin in perspective, addressing its present realities and limitations as a biomaterial and offering an insight into what is required for chitin, and its derivative chitosan, to fulfil its potential as a biomaterial of the 21st Century.The ongoing search for alternative and better ways to treat medical problems is filled with challenges and opportunities. When replacing body parts with artificial substitutes, state-of-the art technology developments such as Tissue Engineering are fuelling the quest for better biomaterials that can meet a myriad of challenges. Central to this goal is the potential for the utilization of materials from nature. Amongst the possible candidates, chitin has been poised to be one such natural material which could be the answer to a variety of needs in the biomedical field. According to researchers, chitin possesses capabilities as a wound dressing, in bone substitutes and in drug delivery carriers, abilities which have evoked great enthusiasm. However this excitement is accompanied by confusion and lack of consensus, and this book also attempts to address these issues.

  • Multivariable System Identification For Process Control

    • 1st Edition
    • Y. Zhu
    • English
    Systems and control theory has experienced significant development in the past few decades. New techniques have emerged which hold enormous potential for industrial applications, and which have therefore also attracted much interest from academic researchers. However, the impact of these developments on the process industries has been limited.The purpose of Multivariable System Identification for Process Control is to bridge the gap between theory and application, and to provide industrial solutions, based on sound scientific theory, to process identification problems. The book is organized in a reader-friendly way, starting with the simplest methods, and then gradually introducing more complex techniques. Thus, the reader is offered clear physical insight without recourse to large amounts of mathematics. Each method is covered in a single chapter or section, and experimental design is explained before any identification algorithms are discussed. The many simulation examples and industrial case studies demonstrate the power and efficiency of process identification, helping to make the theory more applicable. Matlab™ M-files, designed to help the reader to learn identification in a computing environment, are included.

  • The Maternal Brain

    Neurobiological and Neuroendocrine Adaptation and Disorders in Pregnancy and Post Partum
    • 1st Edition
    • Volume 133
    • J.A. Russell + 3 more
    • English
    The adaptive changes within the central nervous system that prepare the body for the physiological requirements of pregnancy and motherhood are of major significance, and many scientists around the world are involved in elucidating these systems in humans and other mammals. The adaptive changes encompass diverse scientific disciplines, including neuroendocrinology, neuroscience and psychology; and failure of appropriate adaptation in mothers can lead to disorders that have profound and long lasting consequences for individuals and for society.This volume contains review articles written by the symposium speakers at a conference held in Bristol in July 1999 entitled: "The Maternal Brain: an International Meeting on Neurobiological and Neuroendocrine Adaptation and Disorders in Pregnancy and Postpartum".This was the first conference to address The Maternal Brain, and comprised wide ranging topics from molecular analysis of physiological systems using transgenic animals, through plasticity at the neurotransmitter and neuronal level, to the description of behavioural adaptation in terms of endocrinology, emotionality and its underlying causes, and analysis of psychosis; all in the peripartum period.

  • Catalyst Deactivation 2001

    Proceedings of the 9th International Symposium, Lexington, KY, USA, October 2001
    • 1st Edition
    • Volume 139
    • J.J. Spivey + 2 more
    • English
    This proceedings contains the papers presented at the 9th International Symposium on Catalyst Deactivation, held in Lexington, KY, USA, on 7-10 October 2001.

  • Reproductive Biotechnology in Finfish Aquaculture

    • 1st Edition
    • C.-S. Lee + 1 more
    • English
    The successful reproduction of cultured brood stock is essential to the sustainable aquaculture of aquatic organisms. This book describes recent advances in the field of finfish reproductive biotechnology. The chapters in this volume are written by eminent scientists who review the progress and assess the status of biotechnology research that is applicable to the reproduction of finfish species for aquaculture. A wide range of topics is included starting with broodstock technologies such as broodstock genetics, broodstock nutrition, environmental control of maturation and impacts of stress on broodstock, gametes and progeny. The volume includes technologies for induction of ovulation and spermiation using synthetic hypothalamic peptides. Gamete technologies which are described include cryopreservation, chromosome set manipulation, disease prevention and control for gametes and embryos and the development of transgenic fish with enhanced production characteristics. Genetic and endocrine technologies for the production of monosex male and female fish stocks are also described.The closing chapter summarizes the discussion of each topic at the workshop, provides recommendations to industry and describes priorities of research and development. Researchers as well as teaching faculty in the aquaculture field will find this volume of great value.

  • Condition Monitoring and Diagnostic Engineering Management

    • 1st Edition
    • A. Starr + 1 more
    • English
    This Proceedings contains the papers presented at the 14th International Conference on Condition Monitoring and Diagnostic Engineering Management (COMADEM 2001), held in Manchester, UK, on 4-6 September 2001. COMADEM 2001 builds on the excellent reputation of previous conferences in this series, and is essential for anyone working in the field of condition monitoring and maintenance management.The scope of the conference is truly interdisciplinary. The Proceedings contains papers from six continents, written by experts in industry and academia the world over, bringing together the latest thoughts on topics including: Condition-based maintenance Reliability centred maintenance Asset management Industrial case studies Fault detection and diagnosis Prognostics Non-destructive evaluation Integrated diagnostics Vibration Oil and debris analysis Tribology Thermal techniques Risk assessment Structural health monitoring Sensor technology Advanced signal processing Neural networks Multivariate statistics Data compression and fusion This Proceedings also contains a wealth of industrial case studies, and the latest developments in education, training and certification. For more information on COMADEM's aims and scope, please visit http://www.comadem.c...

  • Long Term Durability of Structural Materials

    • 1st Edition
    • P.J.M. Monteiro + 3 more
    • English
    "Long Term Durability of Structural Materials" features proceedings of the workshop held at Berkeley, CA in October, 2000. It brought together engineers and scientists, who have received grants from the initiative NSF 98-42, to share their results on the study of long-term durability of materials and structures. The major objective was to develop new methods for accelerated short-term laboratory or in-situ tests which allow accurate, reliable, predictions of the long-term performance of materials, machines and structures. To achieve this goal it was important to understand the fundamental nature of the deterioration and damage processes in materials and to develop innovative ways to model the behavior of these processes as they affect the life and long-term performance of components, machines and structures. The researchers discussed their approach to include size effects in scaling up from laboratory specimens to actual structures. Accelerated testing and durability modeling techniques developed were validated by comparing their results with performance under actual operating conditions. The main mechanism of the deterioration discussed included environmental effects and/or exposure to loads, speeds and other operating conditions that are not fully anticipated in the original design. A broad range of deterioration damage, such as fatigue, overload, ultraviolet damage, corrosion, and wear was presented. A broad range of materials of interest was also discussed, including the full spectrum of construction materials, metals, ceramics, polymers, composites, and coatings. Emphasis was placed on scale-dependence and history of fabrication on resulting mechanical behavior of materials.

  • Side Effects of Drugs Annual

    • 1st Edition
    • Volume 24
    • English
    The Side Effects of Drugs Annual is designed to provide a critical and up-to-date account of new information related to adverse drug reactions and interactions from the clinician's point of view. Under the supervision of the series editors, an international team of expert authors have gathered together the latest information on adverse drug effects from the international literature. In addition to describing new reports of adverse drug effects, the authors have subjected those reports to critical analysis, setting them into context in terms of clinical relevance and importance, and cross-referring to previous reports where necessary. New adverse effects are reported and evaluated and previously reported adverse effects are re-evaluated in the light of the most recent information. A special feature is the reviews, in which selected adverse effects are discussed in depth. The use of the book is enhanced by two separate indexes, allowing the reader to enter the text by drug name, adverse effect name, or drug interaction. The current Annual is the first update of the standard encyclopaedic work in this field, http://www.elsevier.... Side Effects of Drugs, Fourteenth Edition, which was published in December 2000.

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