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Elsevier

Academic Press

  • Molecular Genetics Pt 3

    • 1st Edition
    • Herbert Taylor
    • English
    Molecular Genetics, Part III: Chromosome Structure explores the structure and modification of DNA, chromatin, and higher order organization and possible subunits of chromosomes at the molecular level. It describes major changes in concepts of chromatin structure and packaging of DNA based on studies of nuclease digests and electron micrographs; the role of restriction endonucleases in molecular genetics; the involvement of DNA topoisomerases in concerted breaking and rejoining of DNA backbone bonds; enzymatic methylation of DNA; and transcriptional units in eukaryotic chromosomes. Organized into seven chapters, this volume begins with an overview of the general properties of type I and type II restriction enzymes, basic aspects of restriction enzyme technology, and applications of restriction enzyme technology to the study of chromosome structure and function. It then discusses recombinant DNA technology; possible biological roles of DNA topoisomerases; recognition and control sequences in nucleic acids; composition and substructure of nucleosomes; analysis of chromosome fibers by electron microscopy; organization of fibers into chromosomes; and functional aspects of organization of chromosome fibers. Molecular biologists, geneticists, scientists, and electron microscopists will find this book extremely helpful.

  • Tropical Fruit Processing

    • 1st Edition
    • Jethro Jagtian
    • English
    Tropical Fruit Processing focuses on the improved food preservations methods of tropical fruits for lesser developed and developed countries. This book covers four tropical fruits, namely, guava, mango, papaya, and passion fruit. These fruits have the greatest growth potential based on the knowledge and technology acquired in their cultivation, processing, and preservation. Each chapter in this book discusses the botany, cultivars, horticulture, harvesting, handling, storage, composition, packing, and processing of the fruit. A variety of processed products from these fruits, such as jellies, jams, preserves, purees, sauces, and juices, are also covered. Furthermore, this book describes various food preservation methods including dehydration, concentration, and canning. This book is an invaluable resource for scientists, technologists, manufacturers, students, and others concerned with cultivating, processing, manufacturing, research, development, or marketing of foods.

  • Thermodynamic Properties of Nonelectrolyte Solutions

    • 1st Edition
    • William Acree
    • English
    Thermodynamic Properties of Nonelectrolyte Solutions reviews several of the more classical theories on the thermodynamics of nonelectrolyte solutions. Basic thermodynamic principles are discussed, along with predictive methods and molecular thermodynamics. This book is comprised of 12 chapters; the first of which introduces the reader to mathematical relationships, such as concentration variables, homogeneous functions, Euler’s theorem, exact differentials, and method of least squares. The discussion then turns to partial molar quantities, ideal and nonideal solutions, and empirical expressions for predicting the thermodynamic properties of multicomponent mixtures from binary data. The chapters that follow explore binary and ternary mixtures containing only nonspecific interactions; the thermodynamic excess properties of liquid mixtures and ternary alcohol-hydrocarbon systems; and solubility behavior of nonelectrolytes. This book concludes with a chapter describing the use of gas-liquid chromatography in determining the activity coefficients of liquid mixtures and mixed virial coefficients of gaseous mixtures. This text is intended primarily for professional chemists and researchers, and is invaluable to students in chemistry or chemical engineering who have background in physical chemistry and classical thermodynamics.

  • Biochemistry and Physiology of Protozoa

    • 2nd Edition
    • M Levendowsky
    • English
    Biochemistry and Physiology of Protozoa, Second Edition, Volume 1 is organized into 13 chapters, beginning with a discussion on fine structure and phytogeny of phytoflagellates. This book discusses the structural features of protozoan cytochromes. Subsequent chapters explain sterol and carotenoid distributions in various groups, phycobiliproteins in cryptomonads, halotolerance in Dunaliella, physiology of coccolithophorids, the ameboflagellates, and bioluminescence of phytoflagellates. This edition also describes the most severe and best known of the toxins, saxitoxin, produced by species of Gonyaulax. Lastly, the physiological ecology of red tide flagellates is explained.

  • Antitumor Steroids

    • 1st Edition
    • R T Blickenstaff
    • English
    Antitumor Steroids examines the use of steroids, along with nonsteroidal antiestrogens and some benzo[a]carbazoles, in the treatment of cancer. It explains the mechanism by which steroids and their receptors work together to affect their physiological functions in general and their antitumor activity in particular. It also describes the systematic screening of antitumor compounds isolated from natural sources. Organized into nine chapters, this book begins with an overview of the role of steroids in cancer treatment. It then discusses the estrogens, antiestrogens, and compounds (all containing an aromatic A-ring). The next chapters consider androgens, some antiandrogens, derivatives based on C-19 steroids, progestins and corticoids, bile acids, and compounds with a side-chain carboxyl group. The book explains the biogenesis and metabolism of androgens; the pharmacology of medroxyprogesterone acetate; the antitumor properties of naturally occurring corticosteroids; sterols and cucurbitacins; vitamin D and its metabolites; and cardenolides, bufadienolides, and withanolides. The book concludes with a chapter on bile acids, sapogenins and its analogs, and miscellaneous steroids. This book is a valuable resource for organic and medicinal chemists biochemists, and pharmacologists interested in the use of steroids in treating cancer.

  • Transgenic Plants

    Engineering and Utilization
    • 1st Edition
    • English
    Volumes 1 and 2 of Transgenic Plants assemble important information on transgenic crops which has appeared scattered in many different publications. These two volumes are a significant milestone in plant/agricultural biology, promote the practical application of recombinant DNA technology, and assist in transforming the agricultural industry.

  • Multidimensional Pharmacochemistry

    Design of Safer Drugs
    • 1st Edition
    • Peter Mager
    • English
    Multidimensional Pharmacochemistry: Design of Safer Drugs deals with techniques based on the theory of simultaneous statistical inference and the qualitative rules that can be applied in solving problems of high toxicity. This book points out that the multidimensional view of data analysis can be applied to solve problems in medicinal chemistry. Investigators use different approaches; a certain procedure can prove to be the most beneficial for a specific drug design. This text presents the theoretical assumptions that mathematicians make to derive the basis for their multivariate techniques. This book also describes, in nonmathematical terms, a set of methods that are valuable, as well as explain the different designs by using numerical examples. According to E.J. Ariens, drug action involves the pharmaceutical, pharmacokinetic-toxo... and pharmacodynamics-tox... phases. The multivariate structure-activity analysis (MASCA) Model of Pharmacochemistry is a highly unified multivariate approach to drug design. To develop a multidimensionally oriented pharmacology, the book notes that the investigator can use the "dynamic structure-activity analysis." This entails the experimentalist and chemist using quantitative approaches and intuitive elements from a small number of compounds toward larger groups, with successive changes being inputted in the desired biological activity. This book is strongly recommended for toxicologists, pharmacologists, applied mathematicians, medicinal and agricultural chemists.

  • Molecular Properties V4

    • 1st Edition
    • Douglas Henderson
    • English
    Physical Chemistry: An Advanced Treatise, Volume IV: Molecular Properties provides the aspects of the properties of single molecules and physical methods available for their determination. This book discusses linear polyatomic molecules, quantum-mechanical theory of vibrations, spectra of organic molecules, production and detection of free radicals, and force constants and molecular structure. The Hund's coupling cases for diatomic molecules, methods of measuring dipole moments, NMR spectra, and ESR spectra of organic species are also elaborated. This publication likewise covers the applications of the Mössbauer effect, electric deflection experiments, and effects of intramolecular motions on diffraction patterns. This volume is intended for graduate and physical chemistry students interested in molecular properties.

  • Cellular Responses to Molecular Modulators

    • 1st Edition
    • Lee Mozes
    • English
    Miami Winter Symposia, Volume 18: Cellular Responses to Molecular Modulators is a collection of papers presented at the 13th Miami Winter Symposium held in Miami Beach in 1981 through the joint effort of the University of Miami School of Medicine and the Papanicolaou Cancer Research Institute. Separating 27 manuscripts into chapters, this book begins with a discussion on protein structure and function. This topic is followed by considerable chapters devoted to a whole series of molecules that precisely and specifically modulate a particular behavior and that can be studied in detail in isolated cells in culture. These chapters also look into the research studies on mitogen receptor cytobiochemistry, including special insertion properties and internal migratory fate after binding to effectors. Other chapters discuss the primary gene product containing the thymosin α1 sequence; the purification and production of interferons from cell cultures; the biochemical mechanisms by which interferons modulate cell behavior; and the ability of interferons to regulate natural killer lytic activity at the single cell or population level. The concluding chapters explore the distinct interferon classes by their antigenic, biological, and chemical properties. This book will be of great benefit to cell biologists and researchers.

  • Molecular Spectroscopy

    Modern Research
    • 1st Edition
    • K.N. Rao
    • English
    Molecular Spectroscopy: Modern Research explores the advances in several phases of research in molecular spectroscopy. This eight-chapter book commemorates the 25th anniversary of the annual Columbus Symposium on Molecular Structure and Spectroscopy, held in September, 1970. This book highlights the spectroscopic studies of molecular species in the gas phase and in matrices. Representative articles are also included that cover the applications of molecular studies in a wide variety of areas such as biophysics, astrophysical problems, and energy transfer processes. Other chapters describe the progress achieved in the technology of high resolution spectroscopy and the techniques and terminology of Lamb-dip spectroscopy. A comprehensive bibliography is included for most of the subjects discussed and this text concludes with tables of standard data listing secondary wavelength standards, fundamental constants, atomic masses, and conversion factors of interest to spectroscopists. Spectroscopists, chemists, and researchers will find this work invaluable.

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