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Elsevier

Academic Press

  • Genetic Control of Malaria and Dengue

    • 1st Edition
    • Zach N. Adelman
    • English
    Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown.

  • Principles and Applications of Quantum Chemistry

    • 1st Edition
    • V.P. Gupta
    • English
    Principles and Applications of Quantum Chemistry offers clear and simple coverage based on the author’s extensive teaching at advanced universities around the globe. Where needed, derivations are detailed in an easy-to-follow manner so that you will understand the physical and mathematical aspects of quantum chemistry and molecular electronic structure. Building on this foundation, this book then explores applications, using illustrative examples to demonstrate the use of quantum chemical tools in research problems. Each chapter also uses innovative problems and bibliographic references to guide you, and throughout the book chapters cover important advances in the field including: Density functional theory (DFT) and time-dependent DFT (TD-DFT), characterization of chemical reactions, prediction of molecular geometry, molecular electrostatic potential, and quantum theory of atoms in molecules.

  • Essential Chemistry for Formulators of Semisolid and Liquid Dosages

    • 1st Edition
    • Vitthal S. Kulkarni + 1 more
    • English
    A needed resource for pharmaceutical scientists and cosmetic chemists, Essential Chemistry for Formulators of Semisolid and Liquid Dosages provides insight into the basic chemistry of mixing different phases and test methods for the stability study of nonsolid formulations. The book covers foundational surface/colloid chemistry, which forms the necessary background for making emulsions, suspensions, solutions, and nano drug delivery systems, and the chemistry of mixing, which is critical for further formulation of drug delivery systems into semisolid (gels, creams, lotions, and ointments) or liquid final dosages. Expanding on these foundational principles, this useful guide explores stability testing methods, such as particle size, rheological/viscosit... microscopy, and chemical, and closes with a valuable discussion of regulatory issues. Essential Chemistry for Formulators of Semisolid and Liquid Dosages offers scientists and students the foundation and practical guidance to make and analyze semisolid and liquid formulations.

  • Artificial Neural Network for Drug Design, Delivery and Disposition

    • 1st Edition
    • Munish Puri + 4 more
    • English
    Artificial Neural Network for Drug Design, Delivery and Disposition provides an in-depth look at the use of artificial neural networks (ANN) in pharmaceutical research. With its ability to learn and self-correct in a highly complex environment, this predictive tool has tremendous potential to help researchers more effectively design, develop, and deliver successful drugs. This book illustrates how to use ANN methodologies and models with the intent to treat diseases like breast cancer, cardiac disease, and more. It contains the latest cutting-edge research, an analysis of the benefits of ANN, and relevant industry examples. As such, this book is an essential resource for academic and industry researchers across the pharmaceutical and biomedical sciences.

  • Mushroom Biotechnology

    Developments and Applications
    • 1st Edition
    • Marian Petre
    • English
    Mushroom Biotechnology: Developments and Applications is a comprehensive book to provide a better understanding of the main interactions between biological, chemical and physical factors directly involved in biotechnological procedures of using mushrooms as bioremediation tools, high nutritive food sources, and as biological helpers in healing serious diseases of the human body. The book points out the latest research results and original approaches to the use of edible and medicinal mushrooms as efficient bio-instruments to reduce the environment and food crises. This is a valuable scientific resource to any researcher, professional, and student interested in the fields of mushroom biotechnology, bioengineering, bioremediation, biochemistry, eco-toxicology, environmental engineering, food engineering, mycology, pharmacists, and more.

  • Human Physiology, Biochemistry and Basic Medicine

    • 1st Edition
    • Laurence A. Cole + 1 more
    • English
    Human Physiology, Biochemistry and Basic Medicine is a unique perspective that draws together human biology, physiology, biochemistry, nutrition, and cell biology in one comprehensive volume. In this way, it is uniquely qualified to address the needs of the emerging field of humanology, a holistic approach to understanding the biology of humans and how they are distinguished from other animals. Coverage starts with human anatomy and physiology and the details of the workings of all parts of the male and female body. Next, coverage of human biochemistry and how sugars, fats, and amino acids are made and digested is discussed, as is human basic medicine, covering the science of diseases and human evolution and pseudo-evolution. The book concludes with coverage of basic human nutrition, diseases, and treatments, and contains broad coverage that will give the reader an understanding of the entire human picture.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 72
    • English
    Advances in Clinical Chemistry, Volume 72, the latest installment in this internationally acclaimed series contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Epigenomics in Health and Disease

    • 1st Edition
    • Mario Fraga + 1 more
    • English
    Epigenomics in Health and Disease discusses the next generation sequencing technologies shaping our current knowledge with regards to the role of epigenetics in normal development, aging, and disease. It includes the consequences for diagnostics, prognostics, and disease-based therapies made possible by the study of the complete set of epigenetic modifications to the genetic material of human cells. With coverage pertinent to both basic biology and translational research, the book will be of particular interest for medical and bioscience researchers and students seeking current translational knowledge in epigenesis and epigenomics. Coverage includes the latest findings on epigenome-wide research in disease-based profiling, epidemiological implications, epigenome-wide epigenetic studies, the cancer epigenome, and other pervasive disease categories.

  • Robust Automatic Speech Recognition

    A Bridge to Practical Applications
    • 1st Edition
    • Jinyu Li + 3 more
    • English
    Robust Automatic Speech Recognition: A Bridge to Practical Applications establishes a solid foundation for automatic speech recognition that is robust against acoustic environmental distortion. It provides a thorough overview of classical and modern noise-and reverberation robust techniques that have been developed over the past thirty years, with an emphasis on practical methods that have been proven to be successful and which are likely to be further developed for future applications.The strengths and weaknesses of robustness-enhancing speech recognition techniques are carefully analyzed. The book covers noise-robust techniques designed for acoustic models which are based on both Gaussian mixture models and deep neural networks. In addition, a guide to selecting the best methods for practical applications is provided.The reader will: Gain a unified, deep and systematic understanding of the state-of-the-art technologies for robust speech recognition Learn the links and relationship between alternative technologies for robust speech recognition Be able to use the technology analysis and categorization detailed in the book to guide future technology development Be able to develop new noise-robust methods in the current era of deep learning for acoustic modeling in speech recognition

  • Biology and Evolution of the Mexican Cavefish

    • 1st Edition
    • Alex Keene + 2 more
    • English
    Biology and Evolution of the Mexican Cavefish features contributions by leading researchers in a comprehensive, unique work that examines a number of distinct areas of biology—evolution, development, ecology, and behavior—using the Mexican cavefish as a powerful model system to further understanding of basic biological processes such as eye degeneration, hearing, craniofacial development, sleep, and metabolic function. These fish are currently being used to better understand a number of issues related to human health, including age-related blindness, sleep, obesity, mood-related disorders, and aging. The recent sequencing of the cavefish genome broadens the interest of this system to groups working with diverse biological systems, and has helped researchers identify genes that regulate sleep, eye degeneration, and metabolic function. Mexican cavefish are particularly powerful for the study of biological processes because these fish evolved independently in twenty-nine caves in the Sierra de el Abra Region of Northeast Mexico. These fish have dramatic adaptations to the cave environment, and this can be used to identify genes involved in disease-related traits. This scholarly text will be of interest to researchers and students throughout diverse areas of biology and ecology. It includes photographs of animals and behavior in laboratory and natural settings that will also increase interest and accessibility to non-experts.

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