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  • Differential Equations with Mathematica

    • 4th Edition
    • Martha L. Abell + 1 more
    • English
    Differential Equations with Mathematica, Fourth Edition is a supplementing reference which uses the fundamental concepts of the popular platform to solve (analytically, numerically, and/or graphically) differential equations of interest to students, instructors, and scientists. Mathematica’s diversity makes it particularly well suited to performing calculations encountered when solving many ordinary and partial differential equations. In some cases, Mathematica’s built-in functions can immediately solve a differential equation by providing an explicit, implicit, or numerical solution. In other cases, mathematica can be used to perform the calculations encountered when solving a differential equation. Because one goal of elementary differential equations courses is to introduce students to basic methods and algorithms so that they gain proficiency in them, nearly every topic covered this book introduces basic commands, also including typical examples of their application. A study of differential equations relies on concepts from calculus and linear algebra, so this text also includes discussions of relevant commands useful in those areas. In many cases, seeing a solution graphically is most meaningful, so the book relies heavily on Mathematica’s outstanding graphics capabilities.

  • Drug Metabolism in Diseases

    • 1st Edition
    • Wen Xie
    • English
    Drug Metabolism in Diseases is a comprehensive reference devoted to the current state of research on the impact of various disease states on drug metabolism. The book contains valuable insights into mechanistic effects and examples of how to accurately predict drug metabolism during these different pathophysiological states. Each chapter clearly presents the effects of changes in drug metabolism and drug transporters on pharmacokinetics and disposition. This is a unique and useful approach for all those involved in drug discovery and development, and for clinicians and researchers in drug metabolism, pharmacology, and clinical pharmacology.

  • Anticandidal Agents

    • 1st Edition
    • Awanish Kumar
    • English
    Anticandidal Agents provides the latest information on candida drug resistance and its remedial implications. In this compilation, users will find a comprehensive view on overcoming resistance in anticandidal drugs, along with information on novel molecules. Candida albicans is an opportunistic pathogenic fungus responsible for life threating invasive and nosocomial infections across the globe. Candidiasis is a major cause of morbidity among immunocompromised patients. Infections caused by non-albicans candida like C. glabrata, C. parapsilosis, and C. tropicalis have also imposed a serious threat in the last few decades. Current treatment of candidiasis relies primarily on antifungal agents broadly categorized as azoles, polyenes, echinocandins, allylamines, and pyrimidines. Lately, antifungal resistance has emerged to be an obstruction of current treatment regime. A number of reasons are described in detail. Understanding the mechanisms of resistance is crucial for developing strategies for overcoming the hindrance in current therapeutics.

  • On Human Nature

    Biology, Psychology, Ethics, Politics, and Religion
    • 1st Edition
    • Michel Tibayrenc + 1 more
    • English
    On Human Nature: Biology, Psychology, Ethics, Politics, and Religion covers the present state of knowledge on human diversity and its adaptative significance through a broad and eclectic selection of representative chapters. This transdisciplinary work brings together specialists from various fields who rarely interact, including geneticists, evolutionists, physicians, ethologists, psychoanalysts, anthropologists, sociologists, theologians, historians, linguists, and philosophers. Genomic diversity is covered in several chapters dealing with biology, including the differences in men and apes and the genetic diversity of mankind. Top specialists, known for their open mind and broad knowledge have been carefully selected to cover each topic. The book is therefore at the crossroads between biology and human sciences, going beyond classical science in the Popperian sense. The book is accessible not only to specialists, but also to students, professors, and the educated public. Glossaries of specialized terms and general public references help nonspecialists understand complex notions, with contributions avoiding technical jargon.

  • Fermented Foods in Health and Disease Prevention

    • 1st Edition
    • Juana Frías + 2 more
    • English
    Fermented Foods in Health and Disease Prevention is the first scientific reference that addresses the properties of fermented foods in nutrition by examining their underlying microbiology, the specific characteristics of a wide variety of fermented foods, and their effects in health and disease. The current awareness of the link between diet and health drives growth in the industry, opening new commercial opportunities. Coverage in the book includes the role of microorganisms that are involved in the fermentation of bioactive and potentially toxic compounds, their contribution to health-promoting properties, and the safety of traditional fermented foods. Authored by worldwide scientists and researchers, this book provides the food industry with new insights on the development of value-added fermented foods products, while also presenting nutritionists and dieticians with a useful resource to help them develop strategies to assist in the prevention of disease or to slow its onset and severity.

  • Leadership Lessons for Health Care Providers

    • 1st Edition
    • Frank James Lexa
    • English
    The rapid changes in health care including novel technologies as well as the changing economic, political, and social landscapes are all forcing physicians as well as most types of health care practitioners to re-think their role in leadership. This is particularly true in the US in recent years, but the same issues are widely prevalent affecting health care workers around the globe. Developing capable medical leaders who can navigate these challenges will be essential. Physicians and other health care practitioners usually receive little or no leadership training in the course of their education. At the next steps in their training: internship, residency and fellowship, gaining clinical acumen takes precedence over developing other skills that are at the core of leadership training. Leadership Lessons for Health Care Providers will allow all types of health professionals to gain a better understanding of what leadership is, how to develop their skills while still early in their careers, how to understand and handle common leadership conundrums and chart a path towards increasing their leadership capabilities as they reach mid-career and beyond. This book will provide a great start for those who are interested in learning more about leadership and includes recommendations for next steps at all stages in leadership work.

  • Closed Loop Neuroscience

    • 1st Edition
    • Ahmed El Hady
    • English
    Closed Loop Neuroscience addresses the technical aspects of closed loop neurophysiology, presenting the implementation of these approaches spanning several domains of neuroscience, from cellular and network neurophysiology, through sensory and motor systems, and then clinical therapeutic devices. Although closed-loop approaches have long been a part of the neuroscientific toolbox, these techniques are only now gaining popularity in research and clinical applications. As there is not yet a comprehensive methods book addressing the topic as a whole, this volume fills that gap, presenting state-of-the-art approaches and the technical advancements that enable their application to different scientific problems in neuroscience.

  • Microbial Control of Insect and Mite Pests

    From Theory to Practice
    • 1st Edition
    • Lawrence A. Lacey
    • English
    Microbial Control of Insect and Mite Pests: From Theory to Practice is an important source of information on microbial control agents and their implementation in a variety of crops and their use against medical and veterinary vector insects, in urban homes and other structures, in turf and lawns, and in rangeland and forests. This comprehensive and enduring resource on entomopathogens and microbial control additionally functions as a supplementary text to courses in insect pathology, biological control, and integrated pest management. It gives regulators and producers up-to-date information to support their efforts to facilitate and adopt this sustainable method of pest management. Authors include an international cadre of experts from academia, government research agencies, technical representatives of companies that produce microbial pesticides, agricultural extension agents with hands on microbial control experience in agriculture and forestry, and other professionals working in public health and urban entomology.

  • Genome Stability

    From Virus to Human Application
    • 1st Edition
    • Igor Kovalchuk + 1 more
    • English
    Every species has to preserve the integrity of its genome to ensure faithful passage of genetic information to the progeny. At the same time, there are times during the life of the organism and population in general when a fine balance in genome stability and diversification has to be made to benefit the survival of the species. Genome Stability teaches the reader how various species maintain this fine balance in genome stability and genome diversification in response to their environments. Genome Stability covers a wide range of topics, including the genome stability of DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes and mammals. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability as well as changes in genome stability in response to aging. Finally, Genome Stability covers how epigenetic factors contribute to genome stability and how the species pass the memory of the encounters to the progeny, thus influencing the genome of the progeny in an indirect manner. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly-expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability.

  • Introduction to Robust Estimation and Hypothesis Testing

    • 4th Edition
    • Rand R. Wilcox
    • English
    Introduction to Robust Estimating and Hypothesis Testing, 4th Editon, is a ‘how-to’ on the application of robust methods using available software. Modern robust methods provide improved techniques for dealing with outliers, skewed distribution curvature and heteroscedasticity that can provide substantial gains in power as well as a deeper, more accurate and more nuanced understanding of data. Since the last edition, there have been numerous advances and improvements. They include new techniques for comparing groups and measuring effect size as well as new methods for comparing quantiles. Many new regression methods have been added that include both parametric and nonparametric techniques. The methods related to ANCOVA have been expanded considerably. New perspectives related to discrete distributions with a relatively small sample space are described as well as new results relevant to the shift function. The practical importance of these methods is illustrated using data from real world studies. The R package written for this book now contains over 1200 functions. New to this edition 35% revised content Covers many new and improved R functions New techniques that deal with a wide range of situations

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