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Elsevier

Academic Press

  • Lipid Mediators

    • 1st Edition
    • Fiona M. Cunningham
    • English
    The Handbook of Immunopharmacology: Lipid Mediators covers a comprehensive overview of lipid mediators, from synthesis through to inhibition. The book discusses the metabolism of arachidonic acid; the measurement of fatty acids and their metabolites; and the biological properties of cyclooxygenase products. The text also describes other essential fatty acids, their metabolites and cell-cell interactions; the inhibitors of fatty acid-derived mediators; as well as the biosynthesis and catabolism of platelet-activating factor. The cellular sources of platelet-activating factor and related lipids; the biological properties of platelet-activating factor; and the effects of platelet-activating factor receptor antagonists are also considered. Immunopharmacologist... immunologists, and pharmacologists will find the book invaluable.

  • Molecular Diagnostics

    • 3rd Edition
    • George P. Patrinos + 2 more
    • English
    Molecular Diagnostics, Third Edition, focuses on the technologies and applications that professionals need to work in, develop, and manage a clinical diagnostic laboratory. Each chapter contains an expert introduction to each subject that is next to technical details and many applications for molecular genetic testing that can be found in comprehensive reference lists at the end of each chapter. Contents are divided into three parts, technologies, application of those technologies, and related issues. The first part is dedicated to the battery of the most widely used molecular pathology techniques. New chapters have been added, including the various new technologies involved in next-generation sequencing (mutation detection, gene expression, etc.), mass spectrometry, and protein-specific methodologies. All revised chapters have been completely updated, to include not only technology innovations, but also novel diagnostic applications. As with previous editions, each of the chapters in this section includes a brief description of the technique followed by examples from the area of expertise from the selected contributor. The second part of the book attempts to integrate previously analyzed technologies into the different aspects of molecular diagnostics, such as identification of genetically modified organisms, stem cells, pharmacogenomics, modern forensic science, molecular microbiology, and genetic diagnosis. Part three focuses on various everyday issues in a diagnostic laboratory, from genetic counseling and related ethical and psychological issues, to safety and quality management.

  • Single-Molecule Enzymology: Fluorescence-Based and High-Throughput Methods

    • 1st Edition
    • Volume 581
    • English
    Single-Molecule Enzymology, Part A, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in single-molecule enzymology, and includes sections on such topics as force-based and hybrid approaches, fluorescence, high-throughput sm enzymology, nanopores, and tethered particle motion.

  • Motivation

    Theory, Neurobiology and Applications
    • 1st Edition
    • Volume 229
    • English
    Motivation: Theory, Neurobiology and Applications is inspired by a question central to health care professionals, teachers, parents, and coaches alike, "How can an individual be motivated to perform a given activity or training?" It presents novel measurements of motivation developed in psychology and economics, recent insights into the neurobiology of motivation, and current research on applications designed to boost motivation in neurorehabilitation, education, and sports. In addition, tactics on how to connect these different research and knowledge fields within a common (theoretical) framework of motivation is discussed. Thus, in short, the book provides an integrative, interdisciplinary, up-to-date accounting on the neurobiology of motivation and how it might be boosted.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 97
    • English
    Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology, containing comprehensive reviews of the most current research in applied microbiology. Users will find invaluable references and information on a variety of areas, including protozoan grazing of freshwater biofilms, metals in yeast fermentation processes, the interpretation of host-pathogen dialogue through microarrays, and the role of polyamines in bacterial growth and biofilm formation. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome.

  • Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine

    • 1st Edition
    • Justin Brown + 2 more
    • English
    Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine explores musculoskeletal tissue growth and development across populations, ranging from elite athletes to the elderly. The regeneration and reparation of musculoskeletal tissues present the unique challenges of requiring both the need to withstand distinct forces applied to the body and ability to support cell populations. The book is separated into sections based on tissue type, including bone, cartilage, ligament and tendon, muscle, and musculoskeletal tissue interfaces. Within each tissue type, the chapters are subcategorized into strategies focused on cells, hydrogels, polymers, and other materials (i.e. ceramics and metals) utilized in musculoskeletal tissue engineering applications. In each chapter, the relationships that exist amongst the strategy, stem cell differentiation and somatic cell specialization at the intracellular level are emphasized. Examples include intracellular signaling through growth factor delivery, geometry sensing of the surrounding network, and cell signaling that stems from altered population dynamics.

  • Radio-Frequency Digital-to-Analog Converters

    Implementation in Nanoscale CMOS
    • 1st Edition
    • Morteza S Alavi + 2 more
    • English
    With the proliferation of wireless networks, there is a need for more compact, low-cost, power efficient transmitters that are capable of supporting the various communication standards, including Bluetooth, WLAN, GSM/EDGE, WCDMA and 4G of 3GPP cellular. This book describes a novel idea of RF digital-to-analog converters (RFDAC) and demonstrates how they can realize all-digital, fully-integrated RF transmitters that support all the current multi-mode and multi-band communication standards. With this book the reader will: Understand the challenges of realizing a universal CMOS RF transmitter Recognize the design issues and the advantages and disadvantages related to analog and digital transmitter architectures Master designing an RF transmitter from system level modeling techniques down to circuitdesigns and their related layout know-hows Grasp digital polar and I/Q calibration techniques as well as the digital predistortion approaches Learn how to generate appropriate digital I/Q baseband signals in order to apply them to the test chip and measure the RF-DAC performance.

  • Understanding PCR

    A Practical Bench-Top Guide
    • 1st Edition
    • Sarah Maddocks + 1 more
    • English
    Understanding PCR: A Practical Bench-Top Guide gives you all of the information you need to plan your first PCR, from reagents to conditions to analysis and beyond. It is a user friendly book that has step-by-step basic protocols, which can be adapted to your needs. Includes helpful information such as where to order your reagents and basic troubleshooting hints and tips.

  • Dominance and Aggression in Humans and Other Animals

    The Great Game of Life
    • 1st Edition
    • Henry R. Hermann
    • English
    Dominance and Aggression in Humans and Other Animals: The Great Game of Life examines human nature and the influence of evolution, genetics, chemistry, nurture, and the sociopolitical environment as a way of understanding how and why humans behave in aggressive and dominant ways. The book walks us through aggression in other social species, compares and contrasts human behavior to other animals, and then explores specific human behaviors like bullying, abuse, territoriality murder, and war. The book examines both individual and group aggression in different environments including work, school, and the home. It explores common stressors triggering aggressive behaviors, and how individual personalities can be vulnerable to, or resistant to, these stressors. The book closes with an exploration of the cumulative impact of human aggression and dominance on the natural world.

  • Advances in Genetics

    • 1st Edition
    • Volume 96
    • English
    Advances in Genetics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions.

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