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Elsevier

Academic Press

  • Analytical Methods for Glycerol

    • 1st Edition
    • M. R. F. Ashworth
    • A. A. Newman
    • English
    Analytical Methods for Glycerol covers the detection, identification, determination, and separation of glycerol in analytical procedures. The book discusses the chemical and physical information about glycerol; analytical work on the important naturally occurring and synthetic materials containing combined glycerol; and the analysis of glycerol samples, especially from the point of view of pharmacopoiea specifications. The text also describes the important methods for the enzymic determination of glycerol. Methods based on residual glycerol hydroxyl groups, methods based on the release of glycerol from its combined state in the sample, and methods based on probable participation of the complete molecules of the sample are also considered. Chemists and people involved in the study of analytical methods of glycerol will find the book invaluable.

  • Handbook of Epigenetics

    The New Molecular and Medical Genetics
    • 2nd Edition
    • Trygve O. Tollefsbol
    • English
    Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue and organ regeneration, X-chromosome inactivation, stem cell differentiation, genomic imprinting, and aging. The first edition of this important work received excellent reviews; the second edition continues its comprehensive coverage adding more current research and new topics based on customer and reader reviews, including new discoveries, approved therapeutics, and clinical trials. From molecular mechanisms and epigenetic technology, to discoveries in human disease and clinical epigenetics, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics, to therapeutic interventions for epigenetic-based disorders.

  • Stepped Care for Borderline Personality Disorder

    Making Treatment Brief, Effective, and Accessible
    • 1st Edition
    • Joel Paris
    • English
    Synthesizing the latest research and treatment developments, Stepped Care for Borderline Personality Disorder: Making Treatment Brief, Effective, and Accessible aims to make treatment for borderling personality disorder (BPD) more accessible by providing clinicians with innovative brief and targeted intervention methods. Focusing on integrative treatment models, it offers clinicians a vital guide to the management of patients who are difficult to treat. Acknowleding the early developmental roots of BPD, the book includes sections on BPD in adolescence, childhood precursors of the disorder, and a broad range of etiological factors. It looks at the pitfalls clinicians face when trying to treat BPD, and offers a roadmap to avoiding them.

  • From Artemisia annua L. to Artemisinins

    The Discovery and Development of Artemisinins and Antimalarial Agents
    • 1st Edition
    • Youyou Tu
    • English
    From Artemisia annua L. to Artemisinins: The Discovery and Development of Artemisinins and Antimalarial Agents is the first book that systematically introduces the origin and development of artemisinine and artemisinine-based drugs. It includes four distinct sections, including Artemisia annua L., Artemisinin, Dihydroartemisinin, and other artemisinin derivatives. Tu Youyou, the chief inventor of artemisinin, together with other members from the research team, have written a book that will be a valuable reference work for both researchers involved in the medical industry and scholars who are interested in undertaking innovative research.

  • Chronic Kidney Disease in Disadvantaged Populations

    • 1st Edition
    • Guillermo Garcia-Garcia + 2 more
    • English
    Chronic Kidney Disease in Disadvantaged Populations investigates the increased incidence and prevalence of kidney disease in vulnerable populations world-wide. The volume explores the complex interactions of genetic, biologic, cultural and socioeconomic factors such as the environment, and specific health behaviors that seem to be responsible for a significant proportion of the health disparities in these communities. Each chapter is written by leading experts in the field and analyzes the prevalence and incidence of pre-dialysis kidney disease in disadvantaged populations across both developed and developing countries. In addition, each contribution analyzes differentiated risk factors and compares the disparities in access to screening, prevention strategies, treatment protocols and renal replacement therapies. Chronic Kidney Disease in Disadvantaged Populations is essential reading for residents, fellows, clinicians and biomedical researchers working in nephrology, internal medicine, and epidemiology, especially those working in areas with high concentrations of disadvantaged populations.

  • Western Blotting Guru

    • 1st Edition
    • Ayaz Najafov + 1 more
    • English
    Western Blotting Guru provides researchers in molecular biology with a handy reference for approaching and solving challenging problems associated with immunoblotting setup and optimization. As a laboratory guide, it emphasizes the technical aspects of efficiently employing immunoblotting as a tool in molecular biology laboratories. The book covers the basic science underlying immunoblotting and detailed description of the method parameters, followed by good benchtop practices, tips and tricks for obtaining high-quality data and a detailed troubleshooting guide addressing a variety of problem types.

  • False Allegations

    Investigative and Forensic Issues in Fraudulent Reports of Crime
    • 1st Edition
    • Brent E. Turvey + 2 more
    • English
    False Allegations: Investigative and Forensic Issues in Fraudulent Reports of Crime provides investigators and forensic examiners with a reference manual comprised of objective protocols for managing cases. It helps them understand the nature and extent of false allegations to more accurately identify false allegations should they present in casework. It also prepares users on how to confront and explain false allegations, including instances where colleagues and supervisors may be steeped in bias, denial or self-interest. Responding law enforcement agencies have a duty of care to investigate all reported crime, to recognize and uncover false allegations, and prevent them from causing harm to the innocent. Failure to do so can result in miscarriages of justice. When law enforcement fails in their duty of care, they are also exposed to civil liability from those that have been falsely accused.

  • Structural and Mechanistic Enzymology

    • 1st Edition
    • Volume 109
    • English
    Structural and Mechanistic Enzymology, Volume 109, the latest release in the Advances in Protein Chemistry and Structural Biology series, is an essential resource for protein chemists. Chapters in this new volume include Collagenolytic Matrix Metalloproteinase Structure–Function Relationships: Insights from Molecular Dynamics Studies, Computational Glycobiology: Mechanistic Studies of Carbohydrate-Active Enzymes and Implication for Inhibitor Design, Computational Biochemistry─Enzyme Mechanisms Explored, and A Paradigm for C─H Bond Cleavage: Structural and Functional Aspects of Transition State Stabilization by Mandelate Racemase. This series presents new information on protocols and analysis of proteins, with each volume guest edited by leading experts in a broad range of protein-related topics. This volume presents state-of-the-art contributions, providing insights into the relationship between enzyme structure, catalysis, and function.

  • Engineering Neural Tissue from Stem Cells

    • 1st Edition
    • Stephanie Willerth
    • English
    Engineering Neural Tissue from Stem Cells covers the basic knowledge needed to understand the nervous system and how existing cells can be used to create neural tissue. This book presents a broad range of topics related to the design requirements for engineering neural tissue from stem cells. It begins with the anatomy and function of the central and peripheral nervous system, also covering stem cells, their relation to the nervous system and their function in recovery after injury or disease. In addition, the book explores the role of the extracellular matrix and vasculature/immune system and biomaterials, including their suitability for neural tissue engineering applications.

  • Viral Proteases and Their Inhibitors

    • 1st Edition
    • Satya Prakash Gupta
    • English
    Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the design and development of inhibitors, and analyze the structure-activity relationships of inhibitors. This book is ideal biochemists, virologists and those working on antiviral agents.

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