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  • Illustrated Toxicology

    With Study Questions
    • 1st Edition
    • PK Gupta
    • English
    Illustrated Toxicology: With Study Questions is an essential, practical resource for self-study and guidance catering to a broad spectrum of students. This book covers a range of core toxicological areas, including pesticides, radioactive materials and poisonous plants, also presenting a section on veterinary toxicology. Across 16 chapters, the book presents key concepts with the aid of over 250 detailed, full-color illustrations. Each section is supplemented with practical exercises to support active learning. This combination of clear illustrations and sample testing will help readers gain a deeper understanding of toxicology. This book is useful for toxicology, pharmacy, medical and veterinary students, and also serves as a refresher for academics and professionals in the field, including clinical pharmacists, forensic toxicologists, environmentalists and veterinarians.

  • Intestinal Stem Cell Niche

    • 1st Edition
    • Volume 2
    • English
    Advances in Stem Cells and Their Niches addresses stem cells during development, homeostasis, and disease/injury of the respective organs, presenting new developments in the field, including new data on disease and clinical applications. Video content illustrates such areas as protocols, transplantation techniques, and work with mice.

  • Biopolymers for Food Design

    • 1st Edition
    • Volume 20
    • Alexandru Mihai Grumezescu + 1 more
    • English
    Biopolymers for Food Design, Volume 20 in the Handbook of Bioengineering series, describes how biopolymers have made a major impact in the food industry, from food design, to food control and safety. Biopolymers can be used in the development of novel nutritional alternatives, to replace difficult to obtain food products, or for foods inaccessible or inappropriate for a particular population (i.e. allergic to specific components). In addition, some polymers can be used as functional ingredients, and can also represent efficient scaffolds for food ingredients with therapeutic values. This valuable reference is ideal for those looking for new solutions for the food industry.

  • The Molecular and Cellular Basis of Neurodegenerative Diseases

    Underlying Mechanisms
    • 1st Edition
    • Michael S. Wolfe
    • English
    The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics. Diseases are presented first, with common mechanisms later. Individual chapters discuss each major neurodegenerative disease, integrating this information to offer multiple molecular and cellular mechanisms that diseases may have in common. This book provides readers with a timely update on this rapidly advancing area of investigation, presenting an invaluable resource for researchers in the field.

  • Role of Materials Science in Food Bioengineering

    • 1st Edition
    • Volume 19
    • Alexandru Mihai Grumezescu + 1 more
    • English
    The Role of Materials Science in Food Bioengineering, Volume 19 in the Handbook of Food Bioengineering, presents an up-to-date review of the most recent advances in materials science, further demonstrating its broad applications in the food industry and bioengineering. Many types of materials are described, with their impact in food design discussed. The book provides insights into a range of new possibilities for the use of materials and new technologies in the field of food bioengineering. This is an essential reference on bioengineering that is not only ideal for researchers, scientists and food manufacturers, but also for students and educators.

  • Continuum Mechanics Modeling of Material Behavior

    • 1st Edition
    • Martin H. Sadd
    • English
    Continuum Mechanics Modeling of Material Behavior offers a uniquely comprehensive introduction to topics like RVE theory, fabric tensor models, micropolar elasticity, elasticity with voids, nonlocal higher gradient elasticity and damage mechanics. Contemporary continuum mechanics research has been moving into areas of complex material microstructural behavior. Graduate students who are expected to do this type of research need a fundamental background beyond classical continuum theories. The book begins with several chapters that carefully and rigorously present mathematical preliminaries: kinematics of motion and deformation; force and stress measures; and general principles of mass, momentum and energy balance. The book then moves beyond other books by dedicating several chapters to constitutive equation development, exploring a wide collection of constitutive relations and developing the corresponding material model formulations. Such material behavior models include classical linear theories of elasticity, fluid mechanics, viscoelasticity and plasticity. Linear multiple field problems of thermoelasticity, poroelasticity and electoelasticity are also presented. Discussion of nonlinear theories of solids and fluids, including finite elasticity, nonlinear/non-Newton... viscous fluids, and nonlinear viscoelastic materials are also given. Finally, several relatively new continuum theories based on incorporation of material microstructure are presented including: fabric tensor theories, micropolar elasticity, elasticity with voids, nonlocal higher gradient elasticity and damage mechanics.

  • Targeting Cell Survival Pathways to Enhance Response to Chemotherapy

    • 1st Edition
    • Volume 3
    • English
    Targeting Cell Survival Pathways to Enhance Response to Chemotherapy encompasses recently developed molecular targeting agents and approaches that suppress cell survival signaling. Cell survival signaling attenuates the effectiveness of conventional chemotherapy and numerous mechanisms have been described, and continue to be described, which contribute to cell survival in the face of chemotherapy treatment. Key pathways leading to chemoresistance emanate from growth factor receptors, PI3K, STAT3, anti-apoptotic Bcl-2 family members, autophagy, and the DNA damage response pathway. New advances have underscored the potential of targeting each of these cell survival mechanisms to improve responsiveness to chemotherapy. This book reviews these recent advances and provides a foundational background and hints of new opportunities for basic, translational, and clinical investigators focused on improving therapeutic responses to chemotherapy.

  • Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy

    • 2nd Edition
    • Herbert B. Newton
    • English
    Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy, Second Edition, provides a comprehensive overview of the molecular methodologies in the neuro-oncology field. There have been profound changes in the landscape of approaches to brain tumor therapy since the first edition—mainly in the areas of molecular biology and molecular therapeutics, as well as in the maturation of immunotherapy approaches (e.g., vaccines). This updated edition has a new, primary focus on multidisciplinary molecular methods, and is broadened to include the latest cutting-edge molecular biology, therapeutics, immunobiology and immunotherapy approaches. As the first comprehensive book to address the molecular research into these concepts, users will find it to be an invaluable resource on the topics discussed.

  • Bridging Scales in Modelling and Simulation of Non-Reacting and Reacting Flows. Part I

    • 1st Edition
    • Volume 52
    • English
    Bridging Scales in Modelling and Simulating Reacting Flows, Part I , Volume 52 presents key methods to bridge scales in the simulation of reacting single phase flows. New sections in the updated release include topics such as quadrature-based moment methods for multiphase chemically reacting flows, the collaboration of experiments and simulations for the development of predictive models, a simulation of turbulent coalescence and breakage of bubbles and droplets in the presence of surfactants, a section on salts and contaminants, and information on the numerical simulation of reactive flows.

  • Doherty Power Amplifiers

    From Fundamentals to Advanced Design Methods
    • 1st Edition
    • Bumman Kim
    • English
    Doherty Power Amplifiers: From Fundamentals to Advanced Design Methods is a great resource for both RF and microwave engineers and graduate students who want to understand and implement the technology into future base station and mobile handset systems. The book introduces the very basic operational principles of the Doherty Amplifier and its non-ideal behaviors. The different transconductance requirements for carrier and peaking amplifiers, reactive element effect, and knee voltage effect are described. In addition, several methods to correct imperfections are introduced, such as uneven input drive, gate bias adaptation, dual input drive and the offset line technique. Advanced design methods of Doherty Amplifiers are also explained, including multistage/multiway Doherty power amplifiers which can enhance the efficiency of the amplification of a highly-modulated signal. Other covered topics include signal tracking operation which increases the dynamic range, highly efficient saturated amplifiers, and broadband amplifiers, amongst other comprehensive, related topics.

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