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Elsevier

Academic Press

  • Politics, Practice, and Policy

    How to Get Things Done in Food and Nutrition, 10 Case Studies
    • 1st Edition
    • Eileen Kennedy
    • English
    Food and Nutrition Policy: 10 Case Studies for Developing Effective Policies and Programs explains how policy compromises are reached and then changed over time as new information becomes available. Derived from the authors’ experiences while serving as a political appointee in the federal government, participating in international committees and boards, and from materials from a graduate course which she teaches on global food and nutrition policy at Tufts University, the 10 case studies presented in this book provide real world learning examples on how contentious issues are resolved in the political process.While each of the ten chapters focuses on a specific topic, the book showcases an overriding theme of food and health justice, equity, and empowerment. Readers will deduce key factors to examine pivotal policy decisions while the author dissects polarizing topics such as examining the successes and failures of dietary guidelines, front label packaging approaches, implications of expanding personalized nutrition, the obesity epidemic and the role of GMO’s in agricultural production, and more.

  • The Dual Role of Inflammation in Cancer

    • 1st Edition
    • Surajit Pathak + 1 more
    • English
    The Dual Role of Inflammation in Cancer Genesis and Therapy explores the pivotal role inflammation plays in the development and progression of cancer. The book delves into how chronic inflammation creates a microenvironment that supports tumor growth by promoting cellular proliferation, survival, and migration while suppressing immune responses. It traces historical observations, linking inflammation to cancer while also examining how inflammatory cells and mediators contribute to various stages of tumorigenesis. In addition, it discusses the implications of inflammation on cancer treatment, highlighting the potential of anti-inflammatory agents and immunotherapy in targeting the inflammatory tumor microenvironment.By elucidating on the intricate relationship between inflammation and cancer, the book aims to pave the way for more effective and personalized cancer treatment strategies. As such, it is a valuable resource for researchers in immunology and oncology.

  • Biomass to Biofuel Supply Chain Design and Planning under Uncertainty

    Concepts and Quantitative Methods
    • 2nd Edition
    • Mir Saman Pishvaee + 3 more
    • English
    Biomass to Biofuel Supply Chain Design and Planning Under Uncertainty: Concepts and Quantitative Methods, Second Edition proposes a comprehensive, multi-level framework for optimal biomass-to-biofuel supply chain design and operation, accommodating various types of biomass feedstocks, production pathways, technology options, transportation methods, and final products. This new edition has been thoroughly revised to reflect the latest technological innovations and policy changes while offering a broader range of uncertainty modeling and mathematical programming approaches that cover multi-stage stochastic programming, robust optimization, and probabilistic dynamic programming.These additions provide readers with practical tools to handle the dynamic uncertainties inherent in biofuel supply chains. New case studies and paths to sustainability are also incorporated. By providing an adaptable framework for biofuel supply chain design, focusing on accessible, straightforward quantitative methods, and emphasizing sustainability, this revised edition meets the evolving needs of graduate students, researchers, practitioners, and policymakers seeking to understand biofuel supply chain optimization, uncertainty modeling, and operations. In addition, it helps readers implement practical, sustainable, and regionally applicable optimization solutions.

  • Thiamine, Thiamine Pyrophosphate and Thiamine Pyrophosphate-Dependent Enzymes Part B

    • 1st Edition
    • Volume 736
    • English
    Thiamine Pyrophosphate (TPP)-Dependent Enzymes, Volume 736 in the Methods in Enzymology series covers this diverse group of ubiquitous enzymes with timely chapters on Methods for Studying ThDP-dependent Mycobacterial MenDs (SEPHCHC Synthases), Mammalian 2-hydroxyacyl-CoA lyases, discovery and assays, Anti-infective target 1-deoxy-d-xylulose-5... synthase (DXS) and drug design for enzyme inhibition, Expression, Purification, and Mechanistic Studies of DXP synthases from Deinococcus radiodurans, Plasmodium falciparum, and Plasmodium vivax, Comparison of the catalysis of ThPP-dependent enzymes AHAS, ALS, and DXS, and much more.Additional sections cover Plant and fungal acetohydroxyacid synthases (AHAS): Methods for heterologous expression, kinetic characterization, and structural analysis, Biochemical and Structural characterization of novel ‘split-gene’ archeal transketolases, 4-Hydroxybenzoylform... decarboxylase enzymes from Rhodococcus jostii RHA1 and Pseudomonas fluorescens Pf-5: characterization and involvement in bacterial lignin degradation, Engineering of phosphoketolase from Bifidobacterium adolescentis for increased activity on non-phosphorylated substrates and application in a cell-free reaction system for ATP regeneration, Repurposing TPP-dependent enzymes with anodic oxidation for the conversion of aldehydes to enantioenriched carboxylic acids, and much more.

  • Advances in Brain Tumor Therapy

    From Molecular Mechanisms to Clinical Practice
    • 1st Edition
    • Arun Kumar Singh + 4 more
    • English
    Advances in Brain Tumor Therapy: From Molecular Mechanisms to Clinical Practice explores the evolving landscape of brain tumor treatment, addressing challenges posed by these rare yet impactful malignancies. The book highlights significant improvements in patient prognoses due to advances in targeted therapies and immunotherapies while also recognizing the limitations of current treatment options. The content examines brain tumor epidemiology, incidence, risk factors, and survival rates followed by an extensive overview of existing therapeutic approaches, including clinical trials, targeted treatments, immunotherapies, and systemic therapies. It also delves into the critical signaling pathways that drive tumor biology and implications for future strategies.This book serves as an essential resource for healthcare professionals, clinical researchers, medical students, and scientists, bridging the gap between basic science and clinical practice. By providing insights into the latest advancements and emerging technologies, it equips readers with the knowledge necessary to navigate the complexities of brain tumor therapy and prepare for future innovations.

  • Nonchicken Poultry Production

    • 1st Edition
    • Caven Mguvane Mnisi + 2 more
    • English
    Non-chicken Poultry Production focuses on the modern production of non-chicken poultry birds as alternatives to diversify animal protein options and complement conventional chicken production. The book offers a general review of the sustainable production of non-chicken birds followed by nutritional considerations for each bird of interest. Various strategies to improve the nutrition, welfare, and health of the birds are covered, with an emphasis on long-term economic viability and sustainability. It ultimately examines the future outlook for establishing long-term, sustainable production systems, helping aid academic and industry researchers meet the demand of growing populations and contributing to global food security.Demand for chicken and eggs has surged with population growth, rising income levels, and urbanization. Meeting the demand has proved a challenge for farmers and other stakeholders.

  • Fundamentals and Functional Advancements of Fungal Enzymes in Biorefinery and Bioproducts Development

    Volume 1
    • 1st Edition
    • Manikant Tripathi + 1 more
    • English
    Fundamental and Functional Advancements of Fungal Enzymes in Biorefinery and Bioproducts Development offers highlights the fundamental aspects of fungal enzymes which include their structure, function, chemical composition, and their functional importance for biorefinery and bioproducts development. This is the first of two volumes that provides a comprehensive overview of the utilization of fungal enzymes for biorefinery and bioproduct development. Volume 1 introduces various types of fungal enzymes and offers a better understanding of the basic science of fungal enzymes, their structure, their fundamental functions and limitations in biochemical development. This book also explores the processes involved in improving the enhanced production, efficiency, and efficacy of fungal enzymes for application. It also examines biofuel and bioproducts production using fungal enzymes. In combination with Volume 2, this book offers a holistic view of the potential and challenges of engineered fungal enzymes for researchers, scientists, and industry professionals seeking to deepen their knowledge of fungal enzymes and their role in biochemical advances.

  • Nonthermal Extraction Technologies of Polysaccharides

    Principles, Techniques, Characterization, and Applications
    • 1st Edition
    • Seyed Mohammad Taghi Gharibzahedi
    • English
    Nonthermal Extraction Technologies of Polysaccharides: Principles, Techniques, Characterization, and Applications explores cutting-edge nonthermal extraction technologies, including ultrasound, microwave, high-pressure, pulsed electric field, enzymatic extraction methods, and cold plasma technology and their effects on polysaccharide biofunctionalities, such as antioxidant and antimicrobial properties and potential applications. With an examination of the therapeutic benefits associated with these compounds, including anti-cancer, antioxidant, antimicrobial, anti-inflammatory, and anti-obesity properties, this book aspires to highlight advanced techniques to significantly enhance polysaccharide yield, bioactivity, and purity when compared to traditional approaches.The initial chapters introduce the fundamental structures, sources, and importance of polysaccharides, thus setting the stage for a deeper understanding of their functionality and chemical characterization. By offering both theoretical frameworks and practical guidance, this book equips professionals with the knowledge required to effectively incorporate polysaccharides into health-promoting products for advancing research and applications in the evolving landscape of functional foods and biomedical innovation.

  • Offshore Wind Turbine Foundations

    Advanced Geotechnical Engineering Approaches
    • 1st Edition
    • Susana Lopez-Querol
    • English
    Offshore Wind Turbine Foundations: Advanced Geotechnical Engineering Approaches offers an in-depth exploration of the complex challenges and potential solutions arising in the design and maintenance of offshore wind installations, covering the whole range of OWT foundation types, including gravity-based and deep foundations, suction caissons, and anchors for floating turbines, with special emphasis given to monopiles, as the most common type of foundation at present. Key aspects addressed include current design practices and standards, characterization of soils, sea depth, soil types, and loads, soil-structure interaction, long-term behavior of offshore wind turbines, decommissioning, recycling, and reuse of offshore wind turbine foundations, and future trends. Additionally, valuable case studies are used as a reference for practical guidance and for future designs, helping practitioners to learn from past experiences. By bridging the gap between theoretical concepts, research lines and real applications, this latest volume in the Elsevier Wind Energy Engineering Series will equip both practitioners and researchers with the knowledge and tools needed to address the very particular challenges of offshore wind turbine foundations.

  • Mitochondrial Intoxication

    • 2nd Edition
    • Marcos Roberto de Oliveira
    • English
    Mitochondrial Intoxication, Second Edition, offers a comprehensive and fully updated exploration of the impact of toxic molecules on mitochondrial physiology and the diseases that result from their dysfunction. Divided into three sections, the book opens with a detailed overview of mitochondrial physiology, molecular markers of mitochondrial intoxication, and challenges of mitochondrial profiling during pre-clinical studies. The book then focuses on endogenous toxicants and their impact on mitochondria, including new chapters on lipids, glucose and microbiota-derived toxicants. Amyloid-β peptide and its impact on mitochondrial dysfunction is also a new addition to this book, as well as inflammation-induced mitochondrial intoxication.The final section explores exogenous toxicants, such as pollutants, food additives, illicit and pharmaceutical drugs, pesticides, and heavy metals. The effects of micro- and nanoplastics on mitochondrial function are newly covered. Furthermore, the latest computational tools in mitochondrial toxicity research are investigated. Incorporating the latest advances in the field, this new release offers cutting-edge insights on mitochondrial toxicity, serving as an invaluable resource for researchers and advanced students in cell biology, molecular biology, toxicology, biochemistry, pharmacology, and related fields.

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