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Elsevier

Academic Press

  • Secretory Proteins

    • 1st Edition
    • Volume 133
    • Rossen Donev
    • English
    Secretory Proteins, Volume 133 in the Advances in Protein Chemistry and Structural Biology series highlights new advances in the field, including chapters on Proprotein Convertases regulate trafficking and maturation of key proteins within the secretory pathway, Secretory Proteins in Cancer Diagnosis, Senescent Cells and SASP in Cancer Microenvironment: new approaches in cancer therapy, Autophagy for secretory protein: Therapeutic targets in cancer, Secretory proteins and pathways of secretion of osteosarcoma, Monocyte secretory proteins as drug targets for arresting progression of atherosclerosis, The secretory phenotypes of envenomed cells: insights into venom cytotoxicity, Macromolecules for secretory pathway in SARS-CoV-2 infection, and much more. Other sections cover Exploring the role of secretory proteins in the human infectious diseases diagnosis and therapeutics, Secretory proteins in orchestration of microbial pathogenesis- the curious case of Staphylococcus aureus, Influence of pathological mutations in Aspartylglucosylamin... Deaspartylase causing Aspartylglucosaminur... an in silico approach, and Change in conformational dynamics of Lipase A secretory protein upon mutation causing Wolman disease.

  • Biotechnology for Beginners

    • 3rd Edition
    • Reinhard Renneberg
    • English
    Biotechnology for Beginners, Third Edition presents the latest developments in the evolving field of biotechnology which has grown to such an extent over the past few years that increasing numbers of professional’s work in areas that are directly impacted by the science. This book offers an exciting and colorful overview of biotechnology for professionals and students in a wide array of the life sciences, including genetics, immunology, biochemistry, agronomy and animal science. This book will also appeals to lay readers who do not have a scientific background but are interested in an entertaining and informative introduction to the key aspects of biotechnology. Authors Renneberg and Loroch discuss the opportunities and risks of individual technologies and provide historical data in easy-to-reference boxes, highlighting key topics. The book covers all major aspects of the field, from food biotechnology to enzymes, genetic engineering, viruses, antibodies, and vaccines, to environmental biotechnology, transgenic animals, analytical biotechnology, and the human genome.

  • Hospitalization, Diagnosis, Treatment, and Surgery in Iran

    The Lifecycle of Medical Sciences
    • 1st Edition
    • Ali Akbar Velayati
    • English
    Hospitalization, Diagnosis, Treatment, and Surgery: The Lifecycle of Medical Sciences in Iran provides a complete understanding of the lifecycle of medicine in the underserved area of Iran. Coverage will elucidate the importance of communication between scientists in different countries for the further development of research to advance hospitalization infrastructure, diagnosis and treatment of diseases, and surgery techniques and availability. Using a systematic timeline approach, coverage includes early medical sciences to present day of Iran. Each chapter highlights important research, techniques, and procedures throughout the lifecycle of medical sciences and includes topics from bloodletting and setting bones, to anesthesia and vaccines. The content in each chapter emphasizes standard protocols based on international recognition to help developing countries adopt newer technologies.

  • Venous Ulcers

    • 2nd Edition
    • Cynthia K. Shortell + 1 more
    • English
    Venous Ulcers, Second Edition, provides a comprehensive synthesis of evidence-based recommendations and the highest level of expertise from a leading group of doctors, which is a fundamental constituent for the appropriate management of nonhealing venous wounds in everyday practice. This book offers a fertile environment for a complete understanding of genetics and molecular and biochemical mechanisms that lead to the development and progression of venous ulcers, which is essential for elucidating the underlying pathophysiology and can be utilized for developing novel therapies and accessing previously inaccessible areas of research. Socioeconomic impact, impact on health-related quality of life, the clinical course of the disease, and diagnostic algorithms are elaborated in detail. All currently available treatment modalities are explained in a clinically applicable approach with particular emphasis on operative technique, technical feasibility, success rates (both clinical and technical), and side effects. Lastly, this book elaborates on special diagnostic considerations and management of the most complex patients, often requiring the highest level of expertise for successful treatment.

  • Clinical Management of Pediatric COVID-19

    An International Perspective and Practical Guide
    • 1st Edition
    • Char Leung
    • English
    Clinical Management of Pediatric COVID-19: An International Perspective and Practical Guide provides the most current international research and clinical characteristics of pediatric patients with SARS-CoV-2 infection. Coverage ranges from epidemiology including origin, route of transmission, incubation period, mortality and susceptibility risk factors; to pathogenesis, including difference between the adult and pediatric populations. Diagnosis is covered with special attention to the difference between adult and pediatric patients as well as the differences between newborns, children and adolescents. The book presents current complications, including multisystemic inflammatory syndrome as well as treatment therapies including antiviral and immunomodulatory therapies for this age group. Finally, immunization efficacy and safety are examined. This is the perfect reference to provide guidance to pediatricians on the diagnosis and treatment of SARS-CoV-2, as well as a valuable source of the latest research about the pediatric population for further study.

  • Handbook of Obesity in Obstetrics and Gynecology

    • 1st Edition
    • Tahir A. Mahmood + 1 more
    • English
    **Selected for 2026 Doody's Core Titles in Obstetrics & Gynecology**Handbook of Obesity in Obstetrics and Gynecology addresses all aspects of general obstetrics and gynecology in obese patients, providing evidence-based guidance for the treatment and management of gynecological problems and pregnancy-related care in obese women. The book is a valuable resource for junior doctors, residents and obstetricians and gynecologists looking for a comprehensive guide that addresses the most relevant aspects of obstetric and gynecologic care that are impacted by obesity, an increasingly prevalent condition. The rising prevalence of global obesity is of public health concern, hence obese women suffer from a higher incidence of menstrual disorders, polycystic ovaries, infertility issues, and more.In pregnancy, obesity is associated with an increased risk of early pregnancy loss, recurrent pregnancy loss, fetal developmental abnormalities, thrombo-embolic disease, gestational diabetes, dysfunctional labor, post-partum hemorrhage and difficult operative deliveries.

  • Scattering Methods in Structural Biology Part B

    • 1st Edition
    • Volume 678
    • English
    Scattering Methods in Structural Biology, Part B, Volume 676 in the Methods in Enzymology serial, highlights advances in the field, presenting chapters on Quality controls, Refining biomolecular structures and ensembles by SAXS-driven molecular dynamics simulations, Data analysis and modelling of small-angle scattering data with contrast variation, Observing protein degradation in solution by the PAN-20S proteasome complex: state-of-the-art and future perspectives of TR-SANS as a complementary tool to NMR, crystallography and Cryo-EM, Extracting structural insights from chemically-specific soft X-ray scattering, Reconstruction of 3D density of biological macromolecules from solution scattering, ATSAS- present state and new developments in computational methods, and much more. Additional chapters cover Modeling Structure and Dynamics of Protein Complexes with SAXS Profiles (FoXSDock and MultiFoXS), Validation of macromolecular flexibility in solution by SAXS, Combining NMR, SAXS and SANS to characterize the structure and dynamics of protein complexes, Application of Molecular Simulation Methods to Analyze SAS Data, and more.

  • Nuclear Decommissioning Case Studies: Organization and Management, Economics, and Staying in Business

    • 1st Edition
    • Volume 5
    • Michele Laraia
    • English
    Nuclear Decommissioning Case Studies: Organization and Management, Economics, and Staying in Business is the fifth volume in Michele Laraia’s series, which presents a selection of global case studies on different aspects of nuclear decommissioning. This volume focuses on organization, economics and performance experience, offering the reader guidance on project management, staffing, costs and funding, and training. It guides those responsible for the planning and implementation of nuclear decommissioning to ensure thorough and reliable applications. Decommissioning experts, including regulators, operating organizations, waste managers, researchers, and academics will find this book to be suitable supplementary material to reference works on the theory and applications of nuclear decommissioning. Readers will obtain an understanding of many key case studies, including what happened and what they can learn from the events quoted, to help supplement, solidify, and strengthen their understanding of the topic.

  • Meiosis in Development and Disease

    • 1st Edition
    • Volume 151
    • English
    Meiosis in Development and Disease, Volume 151 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as The initiation stages of meiosis, The molecular basis and dynamics of meiotic cohesions, and their significance in human infertility, Chromatin, recombination, and the centromeres, Sites and structures that mediate segregation when crossing over calls out sick/Life (or at Least Meiosis) Without Crossing Over, Crossover maturation inefficiency, Non coding RNA mediated gene regulation in meiosis, Short chromosomes in meiotic recombination, Chromatin level changes during meiosis initiation vs. oncogenesis, and much more. Other sections of note include Chromosomal speciation revisited: Meiotic recombination and synapsis of evolutionary diverged homologs, Recombination suppression at specific chromosome regions, Unwinding during stressful times - mechanisms of helicases in meiotic recombination, Meiotic functions of PCH-2/TRIP13 and HORMADs, Crossover interference, Checkpoint control in meiotic prophase: Idiosyncratic demands require unique characteristics, The breadth of meiotic drive genes and mechanisms across the tree of life, and many more interesting topics.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 112
    • Gregory S. Makowski
    • English
    Advances in Clinical Chemistry, Volume 112 highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Heterogeneity in Major Depressive Disorder: The need for Biomarker-based and Personalized Treatments, Advances in exosome analysis, Translational Proteomics and Phosphoproteomics: Tissue to Extracellular Vesicles, Immune Checkpoint Therapy, Tumor Immunology, and Biomarkers in Non-Small-Cell Lung Cancer, Advances in Congestive Heart Failure Biomarkers, Fluid biomarkers in Alzheimer’s disease, and more.

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