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Academic Press

  • Metabolic Syndrome

    From Mechanisms to Interventions
    • 1st Edition
    • Satinath Mukhopadhyay + 1 more
    • English
    Metabolic Syndrome: From Mechanisms to Interventions covers all aspects of this complex and multifactorial disease, providing a cutting-edge understanding of the problem of MetS, with a particular focus on its prevention and clinical management. The book discusses practical implementable approaches to its reversal in clinical practice, encompassing the entire spectrum of MetS, from molecular understanding to clinical therapeutics and prevention. This book is a valuable resource for clinicians in multiple specialties, including endocrinologists, diabetologists, hepatologists, gynecologists and researchers in related fields who need a deep understanding of the full range of scientific and clinical aspects of metabolic syndrome.
  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 83
    • English
    Advances in Carbohydrate Chemistry and Biochemistry, Volume 83, the latest release in a serial that highlights new advances in the field, includes a variety of highly sourced chapters written by an international board of authors.
  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 117
    • English
    Advances in Clinical Chemistry, Volume 117, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists.
  • A Blueprint for Implementing Best Practice Procedures in a Digital Forensic Laboratory

    Meeting the Requirements of ISO Standards and Other Best Practices
    • 2nd Edition
    • David Lilburn Watson + 1 more
    • English
    Digital Forensic Processing and Procedures: Meeting the Requirements of ISO 17020, ISO 17025, ISO 27001 and Best Practice Requirements, Second Edition provides a one-stop shop for a set of procedures that meet international best practices and standards for handling digital evidence during its complete lifecycle. The book includes procedures, forms and software, providing anyone who handles digital evidence with a guide to proper procedures throughout chain of custody--from incident response straight through to analysis in the lab. This book addresses the whole lifecycle of digital evidence.
  • Functional Metagenomics

    Microbial Diversity, Interaction, and Application in Bioremediation
    • 1st Edition
    • Maulin P. Shah
    • English
    Functional Metagenomics: Microbial Diversity, Interaction, and Application in Bioremediation uses a 20-chapter, easy-to-understand format to centralize the practical application ideas for functional metagenomics. This important resource not only includes chapters on next-generation sequencing technologies to study important biogeochemical cycles, degradation pathways and detoxification, but also gives insight into several tools that have been developed to integrate metadata and sequence data, allowing downstream comparative analyses of different datasets using several ecological indices. The book's content further explains newly developed techniques for sequencing DNA, generating shorter fragments than Sanger sequencing techniques to quickly read larger sequences in a shorter amount of time. The content finally explores the role of metagenomics in studying microbial diversity, interaction, and application in bioremediation studies and gives the reader overall detailed information regarding metagenomics and its application and techniques.
  • Rigor and Reproducibility in Genetics and Genomics

    Peer-reviewed, Published, Cited
    • 1st Edition
    • English
    Rigor and Reproducibility in Genetics and Genomics: Peer-reviewed, Published, Cited provides a full methodological and statistical overview for researchers, clinicians, students, and post-doctoral fellows conducting genetic and genomic research. Here, active geneticists, clinicians, and bioinformaticists offer practical solutions for a variety of challenges associated with several modern approaches in genetics and genomics, including genotyping, gene expression analysis, epigenetic analysis, GWAS, EWAS, genomic sequencing, and gene editing. Emphasis is placed on rigor and reproducibility throughout, with each section containing laboratory case-studies and classroom activities covering step-by-step protocols, best practices, and common pitfalls. Specific genetic and genomic technologies discussed include microarray analysis, DNA-seq, RNA-seq, Chip-Seq, methyl-seq, CRISPR gene editing, and CRISPR-based genetic analysis. Training exercises, supporting data, and in-depth discussions of rigor, reproducibility, and ethics in research together deliver a solid foundation in research standards for the next generation of genetic and genomic scientists.
  • Picture Fuzzy Logic and Its Applications in Decision Making Problems

    • 1st Edition
    • Chiranjibe Jana + 3 more
    • English
    Picture Fuzzy Logic and Its Applications in Decision Making Problems provides methodological frameworks and the latest empirical research findings in the field of picture fuzzy operators and their applications in scientific research and real-world engineering problems. In this book, picture fuzzy sets are investigated, and different types of operators are defined to solve a number of important decision-making and optimization problems. The hybrid operator on picture fuzzy set based on the combination of picture fuzzy weighted averaging operators and picture fuzzy weighted geometric operators is developed and named Hybrid Picture Fuzzy Weighted Averaging Geometric (H-PFWAG) operator. In addition, another operator is developed for interval-valued picture fuzzy environment, which is named Hybrid Interval-Valued Picture Fuzzy Weighted Averaging Geometric (H-IVPFWAG) operator. These two operators are then demonstrated as solutions to Multiple-Attribute Decision-Making (MADM) problems. The picture fuzzy soft weighted aggregation operators (averaging and geometric) are defined, and these are applied to develop a multi-criteria group decision making system.
  • The Enzymes

    • 1st Edition
    • Volume 54
    • English
    The Enzymes, Volume 54 highlights new advances in enzymes, with new chapters on a variety of topics, including the History of The Enzymes, Impact of The Enzymes in chronicling biochemical processes and pathways, Metabolism and Catalysis, Mitochondrial ATP synthase, The respiratory chain, A century of mitochondrial research, Five decades of metalloenzymology, Mechanisms of catalysis, Mitochondrial fatty acid synthesis and associated processes, Signaling, MAPK cascades: Origins, mechanisms and current status, Sphingolipids: From structural components to signaling hubs, Protein Homeostasis and Hydrolysis, Mitochondrial AAA+ proteases, Hsp70 and JDP proteins: structure-function perspective on molecular chaperone activity. Other sections cover DNA Replication and Repair, Structure-function studies of DNA replication proteins, and Helicases required for nucleotide excision repair.
  • Biochemistry of Collagens, Laminins and Elastin

    Structure, Function and Biomarkers
    • 3rd Edition
    • Morten Karsdal
    • English
    Biochemistry of Collagens, Laminins, and Elastin: Structure, Function and Biomarkers, Third Edition provides current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of these proteins can result in altered signaling properties of the original extracellular matrix (ECM). Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions with ties to endocrine function, and how this knowledge may be used to modulate various pathologies, including fibrotic disease. This new edition has been expanded and revised to incorporate recent research advances. Several new chapters explore a range of chronic diseases in which the ECM and collagens, laminin and elastin are central players in disease modulation, including new chapters on lung, skin and intestinal disease, as well as cancers. The new edition also considers emerging analytical technologies that can detect biomarkers of ECM degradation, with discussion of protein quantification and detecting aging of collagens.
  • Drug-delivery systems of phytochemicals as therapeutic strategies in cancer therapy

    • 1st Edition
    • Akhileshwar Kumar Srivastava + 2 more
    • English
    Drug-delivery Systems of Phytochemicals as Therapeutic Strategies in Cancer Therapy elucidates the importance of various phytochemicals in cancer therapy and explains various routes/methods to deliver phytochemicals for overcoming the problems associated with delivery systems in cancer treatment. Several nanotechnological methods are presented to enhance drug solubility, sustainability, bioavailability, and gastrointestinal permeability of these phytochemicals. Current understanding of the relevant information presented on therapeutic strategies in cancer therapy fulfils the requirements of oncologists, molecular biologists, pharmacologist and related researchers who want to work in the areas of drug development targeting phytochemicals for cancer therapy.