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Journals in Molecular genetics

  • DNA Repair

    • ISSN: 1568-7864
    DNA Repair (DNAREP) is a journal focusing on DNA repair and cellular responses to DNA damage. DNA Repair publishes articles on genetic, cellular, biochemical, structural and molecular aspects of DNA repair. The journal welcomes articles describing databases, methods and new technologies supporting research on DNA repair and responses to DNA damage. Letters to the Editor, hot topics and classics in DNA repair, historical reflections, book reviews and meeting reports will also be considered for publication.The journal publishes topics directly pertaining to DNA damage and repair, which include:ApoptosisBio... responses to genomic insultCell cycle regulationCell fate decisionsEpigenetics and chromatinGenomics/bi... diseases: aging, cancer, and neurological dysfunctionImmune responsesMutagenesis & signature mutationsStructural biology and computational modeling
  • Molecular and Biochemical Parasitology

    • ISSN: 0166-6851
    Molecular and Biochemical Parasitology provides a medium for rapid publication of investigations of the molecular biology and biochemistry of parasitic protozoa, fungi, helminths and ectoparasites, including molecular interactions between parasites and their definitive and intermediate hosts and their vectors.  This includes emerging or neglected eukaryotic pathogens.The main subject areas covered are:• The structure, biosynthesis, degradation, properties and function of parasite biomolecules - DNA, RNA, proteins, lipids, carbohydrates and small molecular-weight substances. This includes molecules of intermediary metabolism and bioenergetics. host-parasite relationships particularly as related to specific parasite molecules. • The response of host organisms to infection, and the response of host cells to intracellular parasites.  Included are studies on the detailed molecular mechanisms of anti-parasitic immune responses, parasite immune evasion, and host-pathogen signalling pathways.• “Omics” technologies and systems biology, including genomics, transcriptomics, proteomics, metabolomics, and epigenomics of parasites and the host’s response to infection.• Vector-parasite relationships at the molecular level; this includes molecular studies on arthropod vectors that transmit parasites, especially those focusing on vector-parasite interactions, vector immunity, and vector control strategies.• Structural studies of parasite proteins and their interactions. • Drug target characterization and the mode of action of antiparasitic drugs; mechanisms of drug resistance; novel therapeutics including natural products, synthetic compounds, and vaccine candidates.  Please note that studies that are restricted to in silico docking of compounds or other purely computational approaches will not be accepted in the absence of some experimental validation.• Analysis of variation in parasite populations relevant to genetic exchange, pathogenesis, drug and vaccine target characterization, and drug resistance; please note that genetic variation data must be supported by phenotypic/experimen... data showing the effect of the variation, and that papers reporting solely on allele frequencies in specific regions will not be accepted.• Parasite protein trafficking, organelle and membrane biogenesis, and cellular structure especially with reference to the roles of specific molecules• Parasite programmed cell death, development, and cell division at the molecular level• Parasitic disease diagnostics, especially molecular diagnostics, biomarkers, and biosensors for parasite detection and disease monitoring.•Microbiomes of parasites, symbiotic relationships, and how microbiota influence parasite development and pathogenicity.• Environmental molecular parasitology, including studies linking molecular parasitology with ecological and environmental factors influencing parasite transmission, adaptation, and evolution.• Methods reports - descriptions of novel or newly-optimized methods with broad applicability to molecular and biochemical parasitologyPapers will only be accepted for publication if they fall within these areas, if they contain original and complete work of high scientific quality, and if they are well presented and clearly written in scientific English. Papers solely confirming the conserved functions of genes previously studied in other organisms will not be considered. We welcome short communications documenting a succinct but clear and important advance.
  • Gene Expression Patterns

    • ISSN: 1567-133X
    Gene Expression Patterns is devoted to the rapid publication of high quality studies of gene expression in development. Studies using cell culture are also suitable if clearly relevant to development, e.g., analysis of key regulatory genes or of gene sets in the maintenance or differentiation of stem cells. Key areas of interest include:In-situ studies such as expression patterns of important or interesting genes at all levels, including transcription and protein expressionTemporal studies of large gene sets during developmentTransgeni... studies to study cell lineage in tissue formation"Omic" studies: In addition of the aims described above, Gene Expression Patterns will publish "Omics" studies (genomics, transcriptomic, proteomics, including single cell RNAseq, etc) relevant for embryo development.
  • Experimental Parasitology

    • ISSN: 0014-4894
    The main focus of Experimental Parasitology is experimental approaches to investigating different aspects of parasitology, including, but not limited to, those encompassed by molecular tools, cell biology, and immunology. The journal predominantly publishes Original Research Papers in which experimentation is used to investigate the physiological, metabolic, immunological, biochemical, nutritional, and chemotherapeutic aspects of parasites and host-parasite relationships. In addition, the journal welcomes Method Papers that describe new approaches to such investigations and Review Articles (short reviews, full reviews, and systematic reviews) that provide critical evaluation of published articles on a theme within the scope of the journal. Furthermore, the journal is open to publishing special issues or meeting reports within the themes of the journal. Please contact the editors for further information. See our Guide for Authors for further information on the different paper types accepted by Experimental Parasitology.
  • Journal of Biotechnology

    • ISSN: 0168-1656
    The Journal of Biotechnology (J. Biotech.) offers publication for both full-length articles and short communications on a wide range of biotechnology-relate... topics. Also, review articles can be submitted if they are pre-approved by one of the editors. The journal will only accept submissions with novel scientific research results that are directly relevant to biotechnological systems and/or applications (for details, please see the list below). J. Biotech. has strict rules about plagiarism. Any submission that includes parts of already published material will be rejected. This includes any attempt to re-publish already published Materials and Methods paragraphs. The journal features a "one-pass review process," i.e., eligible submissions will be reviewed, and those that need improvements (either minor or major) can be resubmitted only once before the decision about whether to accept or reject is decided by the Chief Editor. All figures need to be submitted as high-resolution files during the initial submission. All articles must be written in English, and the quality of the English language will be one of the criteria during the review process.Main Scope of the Journal:Bioprocess engineeringSystem biology, synthetic microbiologyMetaboli... engineering, microbial physiologyBiorefiner... biomass engineeringBiochemic... enzyme/protein engineeringMetabolic engineeringMicrobial expression systemsBiocatalyst engineeringInsect cell-based modelsMultienzyme cascade reactionsPlant-based biotechnologyOutside of the Scope:Manuscripts lacking noveltyReview articles submitted without previous invitation/confirmat... by an editorEnvironmental-... subjects, e.g., waste-water treatment, bioremediation, biodegradationReport... on the cloning and/or expression of naturally occurring enzymes without direct biotechnological applicationResearch on natural products without biotechnological modificationToxicolo... researchPharmacologi... researchFood science-related research without biotechnological applicationEngineeri... articles that do not deal with the direct improvement of biotechnological processesGenome research, especially genome sequencing reports
  • Cancer Letters

    • ISSN: 0304-3835
    Cancer Letters is an international journal providing a forum for original and pertinent contributions in cancer research.Cancer Letters considers full-length articles and Mini Reviews in the broad area of basic and translational oncology. Additionally, Special Issues highlight topical areas in cancer research. Basic areas of interest to a broad readership of Cancer Letters include the molecular genetics and cell biology of cancer, radiation biology, molecular pathology, hormones and cancer, viral oncology, metastasis, and chemoprevention. The journal places emphasis on experimental therapeutics, particularly targeted therapies for personalized cancer medicine, including metronomic chemotherapy.
  • Trends in Genetics

    • ISSN: 0168-9525
    Trends in Genetics was launched in 1985 and quickly became a must read journal for geneticists, known for its concise, accessible articles on a range of topics from developmental biology to evolution. This tradition continues today, and TiG remains a favorite in the community for its distinctive content. As the field has changed, though, so too has the scope of the journal, which now encompasses new areas, such as genomics, epigenetics, and computational genetics, while continuing to cover traditional subjects like transcriptional regulation, population genetics, and chromosome biology. The core aim of the journal, however, is still to provide researchers and students with high-quality, novel reviews, commentaries, and discussions and, above all, to foster an appreciation for the advances being made on all fronts of genetic research.Each issue of TiG contains concise, lively and up-to-date Reviews and Opinions as well as a variety of shorter articles, such as Science & Society and Spotlight pieces. Reviews are invited from leading researchers in a specific field and objectively chronicle recent and important developments. Opinon articles provide a forum for debate and hypothesis, and shorter articles discuss aspects of genetics at the intersection of science and policy as well as emerging ideas in the field. All articles are peer-reviewed.TiG welcomes correspondence. The decision to publish rests with the Editor, and the author(s) of any article discussed in a Letter will normally be invited to reply. Letters may address topics raised in recent issues of the journal, or other matters of general interest to geneticists.Visit the Cell Press website for more information about Trends in Genetics - http://www.cell.com/...
  • Cells & Development

    • ISSN: 2667-2901
    Cell and Developmental Biology and their Quantitative approaches The Official Journal of The International Society of Developmental BiologistsCells & Development is an international journal covering the areas of cell biology and developmental biology. In addition to publishing work at the interphase of these two disciplines, we also publish work that is purely cell biology as well as classical developmental biology.C&D is the official journal of The International Society of Developmental Biologists (ISDB) which supports the world-wide community of developmental biologists.Cells & Development will consider papers in any area of cell biology or developmental biology, in any model system like animals and plants, using a variety of approaches, such as cellular, biomechanical, molecular, quantitative, computational and theoretical biology.Areas of particular interest include:Cell and tissue morphogenesisCell adhesion and migrationCell shape and polarityBiomechanics... modelling of cell and developmental biologyQuantitative biologyStem cell biologyCell differentiationCell proliferation and cell deathEvo-DevoMembran... trafficMetabolic regulationOrgan and organoid developmentRegenerat... at the interface of physics and biology often include theoretical work which is summarised in a short form in a Supplementary Text or Supplementary Theory. Authors may want to further describe, extend and give higher visibility to the theoretical work that they have published in this way. We are therefore pleased to announce that Cells & Development will now consider submissions of extended and more detailed versions of Supplementary Theory material published in other biological or generalist journals. To be considered, these articles must introduce significant additional material and discussion of previously published results. They must explicitly refer to the article where the Supplementary Theory text was originally published. Reproduction of the previously published figures or text materials should be minimal and appropriately referenced, in accordance with copyright requirements of the other journal.With this initiative, Cells & Development is aiming at promoting quantitative approaches to biology by giving the opportunity to theorists to better explain and highlight their contribution to multidisciplinary studies.Cells & Development does not publish descriptive studies of gene expression patterns and molecular screens; for submission of such studies see Gene Expression Patterns .
  • Mutation Research: Fundamental and Molecular Mechanisms of Mutagenesis

    • ISSN: 1386-1964
    A section of Mutation ResearchMutation Research (MR) provides a platform for publishing all aspects of DNA mutations and epimutations, from basic evolutionary aspects to translational applications in genetic and epigenetic diagnostics and therapy. Mutations are defined as all possible alterations in DNA sequence and sequence organization, from point mutations to genome structural variation, chromosomal aberrations and aneuploidy. Epimutations are defined as alterations in the epigenome, i.e., changes in DNA methylation, histone modification and small regulatory RNAs.MR publishes articles in the following areas:Of special interest are basic mechanisms through which DNA damage and mutations impact development and differentiation, stem cell biology and cell fate in general, including various forms of cell death and cellular senescence.The study of genome instability in human molecular epidemiology and in relation to complex phenotypes, such as human disease, is considered a growing area of importance.Mechanism... of (epi)mutation induction, for example, during DNA repair, replication or recombination; novel methods of (epi)mutation detection, with a focus on ultra-high-throughpu... sequencing.Landscape of somatic mutations and epimutations in cancer and aging.Role of de novo mutations in human disease and aging; mutations in population genomics.Interaction... between mutations and epimutations.The role of epimutations in chromatin structure and function.Mitochondri... DNA mutations and their consequences in terms of human disease and aging.Novel ways to generate mutations and epimutations in cell lines and animal models.MR supports and follows the general direction proposed by all major societies in the field part of the International Association of Environmental Mutagenesis and Genomics Societies (IAEMGS):Asociacion Latinoamericana de Mutagenesis, Carcinogenesis y Teratogenesis Ambiental (ALAMCTA)Brazilian Association of Mutagenesis and Environmental Genomics (MutaGen-Brasil)Chin... Environmental Mutagen Society (CEMS)European Environmental Mutagenesis and Genomics Society (EEMGS)Environmental Mutagenesis and Genomics Society (EMGS)Environmental Mutagen Society of India (EMS India)Iranian Environmental Mutagen Society (IrEMS)The Japanese Environmental Mutagen Society (JEMS)Korean Environmental Mutagen Society (KEMS)Molecular and Experimental Pathology Society of Australasia (MEPSA)Pan-African Environmental Mutagen Society (PAEMS)Philippines Environmental Mutagen Society (PEMS)Thai Environmental Mutagen Society (TEMS)Other Mutation Research sections: DNA Repair Mutation Research - Genetic Toxicology and Environmental Mutagenesis (MRGTEM) Mutation Research - Reviews (MRR)
  • Current Opinion in Genetics & Development

    • ISSN: 0959-437X
    Current Opinion in Genetics and Development aims to stimulate scientifically grounded, interdisciplinary, multi-scale debate and exchange of ideas. It contains polished, concise and timely reviews and opinions, with particular emphasis on those articles published in the past two years. In addition to describing recent trends, the authors are encouraged to give their subjective opinion of the topics discussed.In Current Opinion in Genetics and Development we help the reader by providing in a systematic manner:1. The views of experts on current advances in their field in a clear and readable form. 2. Evaluations of the most interesting papers, annotated by experts, from the great wealth of original publications.Current Opinion in Genetics and Development is part of the Current Opinion and Research (CO+RE) suite of journals . CO+RE journals leverage the Current Opinion legacy of editorial excellence, high-impact, and global reach to ensure they are a widely-read resource that is integral to scientists' workflows.Current Opinion in Genetics and Development will serve as an invaluable source of information for researchers, lecturers, teachers, professionals, policy makers and students.Division of the subject into sectionsThe subject of Genetics and Development is divided into six themed sections, each of which is reviewed once a year:• Cancer Genomics • Genome Architecture and Expression • Molecular and genetic basis of disease • Developmental mechanisms, patterning and evolution • Cell reprogramming, regeneration and repair • Genetics of Human Origin / Evolutionary genetics (alternate years)Selection of topics to be reviewedSection Editors, who are major authorities in the field, are appointed by the Editors of the journal. They divide their section into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasised. Section Editors commission reviews from authorities on each topic that they have selected. The Editorial Board provides support to the Editors and the Section Editors with their comments and suggestions on names and topics.Review articles in Current Opinion in Genetics and Development are by invitation only.Review ArticlesThe Current Opinion journals were developed out of the recognition that it is increasingly difficult for specialists to keep up to date with the expanding volume of information published in their subject. In the Current Opinion journals, we help the reader by providing in a systematic manner: (1) The views of experts on current advances in the field in a clear and readable form. (2) Evaluations of the most interesting papers, annotated by experts, from the great wealth of original publications.The aim of the manuscript is to review recent articles, with particular emphasis on those articles published in the past two years. In addition to describing recent trends, you are encouraged to give your subjective opinion of the topics discussed, although you should not concentrate unduly on your own research. Your review should be approximately 2000 words (not including references or reference notes), with approximately 50 references and, as such, the review is intended to be a concise view of the field as it is at the moment, rather than a comprehensive overview. Our audience ranges from student to professor, so articles must be accessible to a wide readership. Please avoid jargon, but do not oversimplify: be accurate and precise throughout. Occasionally, unpublished data can be referred to, but only when essential and should never be used to substantiate any significant point.Please see further information under Writing and Formatting – Additional information.  Editor... OverviewSection Editors write a short overview at the beginning of the section to introduce the reviews and to draw the reader's attention to any particularly interesting developments.This successful format has made Current Opinion in Genetics and Development one of the most highly regarded and highly cited review journals in the field.
  • Mutation Research: Reviews in Mutation Research

    • ISSN: 1383-5742
    The subject areas of Mutation Research - Reviews in Mutation Research (MRR) encompass the entire spectrum of the science of mutation research and its applications, with particular emphasis on the relationship between mutation and disease. Thus, this section will cover:Advances in human genome research (including evolving technologies for mutation detection and functional genomics) with applications in clinical genetics, gene therapy and health risk assessment for environmental agents of concernGenetic toxicology and environmental mutagenesis (including the factors that modulate the genetic activity of environmental agents) will continue to be prominent topics in this section.MRR supports and follows the general direction proposed by all major societies in the field part of the International Association of Environmental Mutagenesis and Genomics Societies (IAEMGS):Asociacion Latinoamericana de Mutagenesis, Carcinogenesis y Teratogenesis Ambiental (ALAMCTA)Brazilian Association of Mutagenesis and Environmental Genomics (MutaGen-Brasil)Chin... Environmental Mutagen Society (CEMS)European Environmental Mutagenesis and Genomics Society (EEMGS)Environmental Mutagenesis and Genomics Society (EMGS)Environmental Mutagen Society of India (EMS India)Iranian Environmental Mutagen Society (IrEMS)The Japanese Environmental Mutagen Society (JEMS)Korean Environmental Mutagen Society (KEMS)Molecular and Experimental Pathology Society of Australasia (MEPSA)Pan-African Environmental Mutagen Society (PAEMS)Philippines Environmental Mutagen Society (PEMS)Thai Environmental Mutagen Society (TEMS)Other Mutation Research sections: DNA Repair Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis (MR) Mutation Research - Genetic Toxicology and Environmental Mutagenesis (MRGTEM)
  • Cancer Letters

    • ISSN: 0304-3835
    Cancer Letters is an international journal providing a forum for original and pertinent contributions in cancer research.Cancer Letters considers full-length articles and Mini Reviews in the broad area of basic and translational oncology. Additionally, Special Issues highlight topical areas in cancer research. Basic areas of interest to a broad readership of Cancer Letters include the molecular genetics and cell biology of cancer, radiation biology, molecular pathology, hormones and cancer, viral oncology, metastasis, and chemoprevention. The journal places emphasis on experimental therapeutics, particularly targeted therapies for personalized cancer medicine, including metronomic chemotherapy.
  • Gene Expression Patterns

    • ISSN: 1567-133X
    Gene Expression Patterns is devoted to the rapid publication of high quality studies of gene expression in development. Studies using cell culture are also suitable if clearly relevant to development, e.g., analysis of key regulatory genes or of gene sets in the maintenance or differentiation of stem cells. Key areas of interest include:In-situ studies such as expression patterns of important or interesting genes at all levels, including transcription and protein expressionTemporal studies of large gene sets during developmentTransgeni... studies to study cell lineage in tissue formation"Omic" studies: In addition of the aims described above, Gene Expression Patterns will publish "Omics" studies (genomics, transcriptomic, proteomics, including single cell RNAseq, etc) relevant for embryo development.
  • DNA Repair

    • ISSN: 1568-7864
    DNA Repair (DNAREP) is a journal focusing on DNA repair and cellular responses to DNA damage. DNA Repair publishes articles on genetic, cellular, biochemical, structural and molecular aspects of DNA repair. The journal welcomes articles describing databases, methods and new technologies supporting research on DNA repair and responses to DNA damage. Letters to the Editor, hot topics and classics in DNA repair, historical reflections, book reviews and meeting reports will also be considered for publication.The journal publishes topics directly pertaining to DNA damage and repair, which include:ApoptosisBio... responses to genomic insultCell cycle regulationCell fate decisionsEpigenetics and chromatinGenomics/bi... diseases: aging, cancer, and neurological dysfunctionImmune responsesMutagenesis & signature mutationsStructural biology and computational modeling
  • Experimental Parasitology

    • ISSN: 0014-4894
    The main focus of Experimental Parasitology is experimental approaches to investigating different aspects of parasitology, including, but not limited to, those encompassed by molecular tools, cell biology, and immunology. The journal predominantly publishes Original Research Papers in which experimentation is used to investigate the physiological, metabolic, immunological, biochemical, nutritional, and chemotherapeutic aspects of parasites and host-parasite relationships. In addition, the journal welcomes Method Papers that describe new approaches to such investigations and Review Articles (short reviews, full reviews, and systematic reviews) that provide critical evaluation of published articles on a theme within the scope of the journal. Furthermore, the journal is open to publishing special issues or meeting reports within the themes of the journal. Please contact the editors for further information. See our Guide for Authors for further information on the different paper types accepted by Experimental Parasitology.
  • Journal of Biotechnology

    • ISSN: 0168-1656
    The Journal of Biotechnology (J. Biotech.) offers publication for both full-length articles and short communications on a wide range of biotechnology-relate... topics. Also, review articles can be submitted if they are pre-approved by one of the editors. The journal will only accept submissions with novel scientific research results that are directly relevant to biotechnological systems and/or applications (for details, please see the list below). J. Biotech. has strict rules about plagiarism. Any submission that includes parts of already published material will be rejected. This includes any attempt to re-publish already published Materials and Methods paragraphs. The journal features a "one-pass review process," i.e., eligible submissions will be reviewed, and those that need improvements (either minor or major) can be resubmitted only once before the decision about whether to accept or reject is decided by the Chief Editor. All figures need to be submitted as high-resolution files during the initial submission. All articles must be written in English, and the quality of the English language will be one of the criteria during the review process.Main Scope of the Journal:Bioprocess engineeringSystem biology, synthetic microbiologyMetaboli... engineering, microbial physiologyBiorefiner... biomass engineeringBiochemic... enzyme/protein engineeringMetabolic engineeringMicrobial expression systemsBiocatalyst engineeringInsect cell-based modelsMultienzyme cascade reactionsPlant-based biotechnologyOutside of the Scope:Manuscripts lacking noveltyReview articles submitted without previous invitation/confirmat... by an editorEnvironmental-... subjects, e.g., waste-water treatment, bioremediation, biodegradationReport... on the cloning and/or expression of naturally occurring enzymes without direct biotechnological applicationResearch on natural products without biotechnological modificationToxicolo... researchPharmacologi... researchFood science-related research without biotechnological applicationEngineeri... articles that do not deal with the direct improvement of biotechnological processesGenome research, especially genome sequencing reports
  • Cells & Development

    • ISSN: 2667-2901
    Cell and Developmental Biology and their Quantitative approaches The Official Journal of The International Society of Developmental BiologistsCells & Development is an international journal covering the areas of cell biology and developmental biology. In addition to publishing work at the interphase of these two disciplines, we also publish work that is purely cell biology as well as classical developmental biology.C&D is the official journal of The International Society of Developmental Biologists (ISDB) which supports the world-wide community of developmental biologists.Cells & Development will consider papers in any area of cell biology or developmental biology, in any model system like animals and plants, using a variety of approaches, such as cellular, biomechanical, molecular, quantitative, computational and theoretical biology.Areas of particular interest include:Cell and tissue morphogenesisCell adhesion and migrationCell shape and polarityBiomechanics... modelling of cell and developmental biologyQuantitative biologyStem cell biologyCell differentiationCell proliferation and cell deathEvo-DevoMembran... trafficMetabolic regulationOrgan and organoid developmentRegenerat... at the interface of physics and biology often include theoretical work which is summarised in a short form in a Supplementary Text or Supplementary Theory. Authors may want to further describe, extend and give higher visibility to the theoretical work that they have published in this way. We are therefore pleased to announce that Cells & Development will now consider submissions of extended and more detailed versions of Supplementary Theory material published in other biological or generalist journals. To be considered, these articles must introduce significant additional material and discussion of previously published results. They must explicitly refer to the article where the Supplementary Theory text was originally published. Reproduction of the previously published figures or text materials should be minimal and appropriately referenced, in accordance with copyright requirements of the other journal.With this initiative, Cells & Development is aiming at promoting quantitative approaches to biology by giving the opportunity to theorists to better explain and highlight their contribution to multidisciplinary studies.Cells & Development does not publish descriptive studies of gene expression patterns and molecular screens; for submission of such studies see Gene Expression Patterns .
  • Molecular Immunology

    • ISSN: 0161-5890
    Molecular Immunology publishes original articles, reviews and commentaries on all areas of immunology, with a particular focus on description of cellular, biochemical or genetic mechanisms underlying immunological phenomena. Studies on all model organisms, from invertebrates to humans, are suitable. Examples include, but are not restricted to:Infection, autoimmunity, transplantation, immunodeficiencies, inflammation and tumor immunologyMechanisms of induction, regulation and termination of innate and adaptive immunityIntercellula... communication, cooperation and regulationIntracellu... mechanisms of immunity (endocytosis, protein trafficking, pathogen recognition, antigen presentation, etc)Mechanisms of action of the cells and molecules of the immune systemStructural analysisDevelopment of the immune systemComparative immunology and evolution of the immune system"Omics" studies and bioinformaticsVaccin... biotechnology and therapeutic manipulation of the immune system (therapeutic antibodies, cytokines, cellular therapies, etc)Technical developmentsArticles based primarily on studies in silico must adhere to the following principles; (i) The article must report novel analytical tools, approaches and/or databases rather than using publicly available ones; or (ii) The article must include substantial experimental validation of the conclusions obtained in silico.Manuscripts related to regulatory RNA (e.g. microRNAs, lncRNAs or circRNAs) are welcome but please note: (i) they must show clear physiological relevance supported by in vivo results or clinical observations; (ii) Correlations between regulatory RNA expression with human diseases should be experimentally validated; (iii) Functions associated with the regulatory RNAs must within the scope of the journal i.e. inflammation and/or immune responses.To be acceptable for publication, studies that describe correlations between disease and genetic polymorphisms would normally be required to include novel mechanistic findings underlying the associations.Clinica... studies correlating disease and measurements of a molecule or cell type would likewise not be suitable for publication without novel mechanistic insights.Studies describing pharmacological agents are welcome if they provide significant novelty on the mechanisms of action.
  • Gene

    • ISSN: 0378-1119
    Gene is dedicated to advancing understanding of genes and genomes, including their regulation, expression, function, and evolution, and their roles in biological processes, phenotypes, and diseases across all biological systems, from prokaryotes to eukaryotes and viruses.The journal provides a broad and inclusive forum for genetics and genomics research spanning molecular, cellular, organismal, and evolutionary biology. Gene welcomes well-executed studies across diverse organisms and approaches and encourages contributions that provide insights into gene function and genome biology, including those linking genetic or genomic variations to biological processes, phenotypes, or diseases. With its wide scope, the journal supports the dissemination of sound research, while promoting studies that contribute to biological understanding. Computational approaches are welcome, including quantitative, statistical, and data‑driven analyses of genetic and genomic data, provided they are supported by appropriate experimental evidence or other compelling lines of validation that substantiate their biological conclusions.The journal publishes original research articles, reviews, and short communications. Topics covered in the journal include, but are not limited toGene regulation, transcription, RNA biology, and epigeneticsGenome organization, chromatin structure, and nuclear architectureFunction... genomics and multi-omics approachesComputatio... and data-driven approaches to genetics and genomicsGenome editing, genetic engineering, and synthetic biologyHuman, animal, plant, microbial, and viral geneticsDisease and cancer genetics, including molecular mechanisms and genotype–phenotype relationshipsEvoluti... comparative, and population genomicsSystems biology and gene regulatory networksThe journal does not generally consider manuscripts that are solely descriptive, lack clear biological or genetic relevance, or do not support their main conclusions with appropriate analysis or evidence. Case reports and study types that do not directly advance understanding of gene function or genome biology are also outside the scope of the journal.Gene is part of the Gene Family of journals, including Gene Reports, Human Gene, and Plant Gene, providing a comprehensive forum for research on genes, genetic variation, and gene function across biological systems.