Gene

Gene is dedicated to advancing understanding of genes and genomes, including their regulation, expression, function, and evolution, and their roles in biological processes, phenotypes, and diseases across all biological systems, from prokaryotes to eukaryotes and viruses.

The journal provides a broad and inclusive forum for genetics and genomics research spanning molecular, cellular, organismal, and evolutionary biology. Gene welcomes well-executed studies across diverse organisms and approaches and encourages contributions that provide insights into gene function and genome biology, including those linking genetic or genomic variations to biological processes, phenotypes, or diseases. With its wide scope, the journal supports the dissemination of sound research, while promoting studies that contribute to biological understanding.

Computational approaches are welcome, including quantitative, statistical, and data‑driven analyses of genetic and genomic data, provided they are supported by appropriate experimental evidence or other compelling lines of validation that substantiate their biological conclusions.

The journal publishes original research articles, reviews, and short communications. Topics covered in the journal include, but are not limited to

• Gene regulation, transcription, RNA biology, and epigenetics

• Genome organization, chromatin structure, and nuclear architecture

• Functional genomics and multi-omics approaches

• Computational and data-driven approaches to genetics and genomics

• Genome editing, genetic engineering, and synthetic biology

• Human, animal, plant, microbial, and viral genetics

• Disease and cancer genetics, including molecular mechanisms and genotype–phenotype relationships

• Evolutionary, comparative, and population genomics

• Systems biology and gene regulatory networks

The journal does not generally consider manuscripts that are solely descriptive, lack clear biological or genetic relevance, or do not support their main conclusions with appropriate analysis or evidence. Case reports and study types that do not directly advance understanding of gene function or genome biology are also outside the scope of the journal.

Gene is part of the Gene Family of journals, including Gene Reports, Human Gene, and Plant Gene, providing a comprehensive forum for research on genes, genetic variation, and gene function across biological systems.