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Elsevier

Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • Pyrolysis of Organic Molecules

    Applications to Health and Environmental Issues
    • 2nd Edition
    • Serban C. Moldoveanu
    • English
    Pyrolysis of Organic Molecules: Applications to Health and Environmental Issues, Second Edition offers a systematic presentation of pyrolysis results for the main classes of non-polymeric organic molecules. It covers a large body of data published on pyrolysis, as well as numerous original contributions to the pyrolysis of compounds not previously studied. This thoroughly revised edition contains new results reported in the literature since the first edition published, including the generation of traces of toxic compounds in various pyrolytic processes; the pyrolysis in the presence of catalysts and solid supports such as alumina, silica, and non-inert metals; and pyrolysis of specific mixtures of compound such as amino acids plus carbohydrates. This new information regarding the pyrolysis of these mixtures has greatly improved the utility of the book, making Pyrolysis of Organic Molecules an essential resource for chemists and chemical engineers involved in processes related to pyrolysis, as well as toxicologists and environmentalists.

  • Progress in Heterocyclic Chemistry

    • 1st Edition
    • Volume 30
    • Gordon Gribble + 1 more
    • English
    Progress in Heterocyclic Chemistry (PHC), Volume 30, the latest in this annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC), contains both highlights of the previous year’s literature on heterocyclic chemistry and articles on new and developing topics of interest. Chapters in this updated volume are all written by leading researchers in their field, providing a systematic survey of the important, original material reported in literature in 2017. As with previous volumes in the series, this update will enable academics, industrial chemists and advanced students to keep abreast of developments in heterocyclic chemistry in a convenient resource.

  • Anionic Annulations in Organic Synthesis

    A Versatile and Prolific Class of Ring-Forming Reactions
    • 1st Edition
    • Dipakranjan Mal
    • English
    Anionic Annulations in Organic Synthesis: A Versatile and Prolific Class of Ring-Forming Reactions is a comprehensive review of the main annulations for the construction of cyclic structures and their use in the total synthesis of functional molecules. The book explores in detail the Hauser, Robinson, Sammes, and Myers annulations, all of which are beneficial to constructing substrates with complex molecular structures suitable for pharmaceutical purposes. This volume begins with an in-depth introduction on the history and perspectives of annulations. It then covers different categories of annulation in each chapter, examining their application to drug synthesis for a range of different medicinal compounds. Anionic Annulations in Organic Synthesis delivers a thorough analysis of the topic and provides the tools necessary to master anionic organic chemistry. It is a valuable resource for chemists, researchers, and students seeking a complete and detailed understanding of anionic annulations.

  • Computational Quantum Chemistry

    Insights into Polymerization Reactions
    • 1st Edition
    • Masoud Soroush
    • English
    Computational Quantum Chemistry: Insights into Polymerization Reactions consolidates extensive research results, couples them with computational quantum chemistry (CQC) methods applicable to polymerization reactions, and presents those results systematically. CQC has advanced polymer reaction engineering considerably for the past two decades. The book puts these advances into perspective. It also allows you to access the most up-to-date research and CQC methods applicable to polymerization reactions in a single volume. The content is rigorous yet accessible to graduate students as well as researchers who need a reference of state-of-the-art CQC methods with polymerization applications.

  • Fluorine

    A Paradoxical Element
    • 1st Edition
    • Volume 5
    • Alain Tressaud
    • English
    Fluorine: A Paradoxical Element, Volume Five, deals with the link between fluorine, humanity and the environment. It is divided into three main sections, including i) The history and developmental stages of fluorinated products, ii) Awareness of its importance in our environment, and iii) Recent contributions of fluoride products in medicine, pharmacy and our daily lives. Made engaging through interesting figures and accessible language, and written by a leading expert, Professor Tressaud, the book supports the work of scientists working in materials, toxicology and environmental science. It complements the author’s edited series, Progress in Fluorine Science, covering recent advances.

  • The Handbook of Metabolic Phenotyping

    • 1st Edition
    • John C. Lindon + 2 more
    • English
    The Handbook of Metabolic Phenotyping is the definitive work on the rapidly developing subject of metabolic phenotyping. It explores in detail the wide array of analytical chemistry and statistical modeling techniques used in the field, coupled with surveys of the various application areas in human development, nutrition, disease, therapy, and epidemiology to create a comprehensive exploration of the area of study. It covers recent studies that integrate the various -omics data sets to derive a systems biology view. It also addresses current issues on standardization, assay and statistics validation, and data storage and sharing. Written by experts with many years of practice in the field who pioneered many of the approaches widely used today, The Handbook of Metabolic Phenotyping is a valuable resource for postgrads and research scientists studying and furthering the field of metabolomics.

  • Nano-inspired Biosensors for Protein Assay with Clinical Applications

    • 1st Edition
    • Genxi Li
    • English
    Nano-inspired Biosensors for Protein Assay with Clinical Applications introduces the latest developments in nano-inspired biosensing, helping readers understand both the fundamentals and frontiers in this rapidly advancing field. In recent decades, there has been increased interest in nano-inspired biosensors for clinical application. Proteins, e.g. antigen-antibody, tumor markers and enzymes are the most important target in disease diagnosis, and a variety of biosensing techniques and strategies have been developed for protein assay. This book brings together all the current literature on the most recent advances of protein analysis and new methodologies in designing new kinds of biosensors for clinical diagnostic use.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 86
    • English
    Advances in Clinical Chemistry, Volume 86, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 58
    • Atta-ur Rahman
    • English
    Studies in Natural Products Chemistry, Volume 58, covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development in the pharmaceutical industry.

  • The Alkaloids

    • 1st Edition
    • Volume 80
    • English
    The Alkaloids, Volume 80, is the newest release in a series that has covered the topic for more than 60 years. As the esteemed, leading reference in the field of alkaloid chemistry, this series covers all aspects of alkaloids, including their chemistry, biology and pharmacology. Sections are presented as high-quality, timeless reviews written by renowned experts in the field, with this new release focusing on pyrrolizidine alkaloids.

  • Alteration of Ovoproducts

    From Metabolomics to Online Control
    • 1st Edition
    • Olivier Goncalves + 1 more
    • English
    Characterizing the Alteration of Ovoproducts Using New Analytical Approaches focuses on the capabilities (potential or proven) of the latest metabolomics based analytical approaches for the (early) diagnostic of the alteration of ovoproducts during their production/preservat... processes. It details the ovoproduct matrix, their known sources of biotic and abiotic alteration, and their associated biomarkers. In addition, the book covers the capabilities (exploratory and characterization) of the latest metabolomics tecnics, both invasive and non-invasive, including chromatography, nuclear magnetic resonance, mass spectrometry, NMR, MS – including FTICR-MS –, and vibrational spectroscopy, such as Infrared – MIR, NIR – or Raman). In final sections, the next generation of online sensors derived from the latest technics is discussed for their applicative potential in industry (NIR, Raman, chromatography, benchmark NMR, and more).

  • Physical Chemistry

    Multidisciplinary Applications in Society
    • 1st Edition
    • Kenneth S Schmitz
    • English
    The advancements in society are intertwined with the advancements in science. To understand how changes in society occurred, and will continue to change, one has to have a basic understanding of the laws of physics and chemistry. Physical Chemistry: Multidisciplinary Applications in Society examines how the laws of physics and chemistry (physical chemistry) explain the dynamic nature of the Universe and events on Earth, and how these events affect the evolution of society (multidisciplinary applications). The ordering of the chapters reflects the natural flow of events in an evolving Universe: Philosophy of Science, the basis of the view that natural events have natural causes - Cosmology, the origin of everything from the Big Bang to the current state of the Universe - Geoscience, the physics and chemistry behind the evolution of the planet Earth from its birth to the present - Life Science, the molecules and mechanisms of life on Earth - Ecology, the interdependence of all components within the Ecosphere and the Universe - Information Content, emphasis on how words and phrases and framing of issues affect opinions, reliability of sources, and the limitations of knowledge.

  • Key Heterocycle Cores for Designing Multitargeting Molecules

    • 1st Edition
    • Om Silakari
    • English
    Key Heterocycle Cores for Designing Multitargeting Molecules provides a helpful overview of current developments in the field. Following a detailed introduction to the manipulation of heterocycle cores for the development of dual or multitargeting molecules, the book goes on to describe specific examples of such developments, focusing on compounds such as Benzimidazole, Acridine, Flavones, Thiazolidinedione and Oxazoline. Drawing on the latest developments in the field, this volume provides a valuable guide to current approaches in the design and development of molecules capable of acting on multiple targets. Adapting the heterocyclic core of a single-target molecule can facilitate its development into an agent capable of acting on multiple targets. Such multi-targeting drugs have the potential to become essential components in the design of novel, holistic treatment plans for complex diseases, making the design of such active agents an increasingly important area of research.

  • Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides

    • 1st Edition
    • Anant R. Kapdi + 2 more
    • English
    Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides describes the procedures and protocols related to the modification of nucleosides, nucleotides and oligonucleotides via Pd-mediated cross-coupling processes. The book highlights the growing area of nucleic acid modification and how Pd-mediated coupling reactions can assist this development. Users will find key synthetic protocols for these reactions in this latest volume in the Latest Trends in Palladium Chemistry series. As most of the research in the field of antiviral agents has centered on the use of modified nucleosides that have exhibited promising activity, this book provides an up-to-date reference for both professionals in industry and other interested parties.

  • Physical Chemistry of Gas-Liquid Interfaces

    • 1st Edition
    • Jennifer A. Faust + 1 more
    • English
    Physical Chemistry of Gas-Liquid Interfaces, the first volume in the Developments in Physical & Theoretical Chemistry series, addresses the physical chemistry of gas transport and reactions across liquid surfaces. Gas–liquid interfaces are all around us, especially within atmospheric systems such as sea spry aerosols, cloud droplets, and the surface of the ocean. Because the reaction environment at liquid surfaces is completely unlike bulk gas or bulk liquid, chemists must readjust their conceptual framework when entering this field. This book provides the necessary background in thermodynamics and computational and experimental techniques for scientists to obtain a thorough understanding of the physical chemistry of liquid surfaces in complex, real-world environments.

  • Chiral Analysis

    Advances in Spectroscopy, Chromatography and Emerging Methods
    • 2nd Edition
    • P.L. Polavarapu
    • English
    Chiral Analysis: Advances in Spectroscopy, Chromatography and Emerging Methods, Second Edition covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals, including chemistry graduate students, analytical chemists, organic chemists, professionals in the pharmaceutical industry, and others with an interest in chirality and chiral analysis. This thoroughly revised second edition covers several new, important areas of chiral analysis that have emerged since the first edition. Three of the new methods provide higher sensitivity than can be realized with the current methods and are expected to become mainstream applications: cavity based methods offer vastly higher sensitivity than conventional polarimetric methods, microwave chiral detection provides unsurpassed sensitivity for identifying diastereomers, and the rotating electric field method offers a competing new approach for the separation of enantiomers. Another topic, chirality in extraterrestrial life, has not been discussed in any other book and is important for understanding the origin of life.

  • Biological Inorganic Chemistry

    A New Introduction to Molecular Structure and Function
    • 3rd Edition
    • Robert R. Crichton
    • English
    Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function, Third Edition, provides a comprehensive discussion of the biochemical aspects of metals in living systems. The fascinating world of the role of metals in biology, medicine and the environment has progressed significantly since the very successful Second Edition of the book published in 2012. Beginning with an overview of metals and selected nonmetals in biology, the book supports the interdisciplinary nature of this vibrant area of research by providing an introduction to basic coordination chemistry for biologists and structural and molecular biology for chemists. Having built this accessible foundation, the book progresses to discuss biological ligands for metal ions, intermediary metabolism and bioenergetics, and methods to study metals in biological systems. The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses nickel and cobalt enzymes; manganese chemistry and biochemistry; molybdenum, tungsten, vanadium, and chromium; non-metals in biology; biomineralization; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment. Now in its Third Edition, this popular and award-winning resource highlights recent exciting advances and provides a thorough introduction for both researchers approaching the field from a variety of backgrounds, as well as advanced students.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 126
    • English
    Advances in Heterocyclic Chemistry, Volume 126, is the definitive series in the field, one that is of great importance to organic chemists, polymer chemists and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature is used more frequently in explanations. Updates to this release include sections on The Literature of Heterocyclic Chemistry, Part XVI, 2016, The preparation and properties of heteroarylazulenes and hetero-fused azulenes, Recent developments in pyrazole chemistry, Yne, Ene-Yne Synthetic Approaches to Heterocycles, Appel Salt and Heterocycles: A review of Thirty Years of 4,5-Dichloro-1,2,3-d... Chloride Chemistry, and more. Written by established authorities in the field, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds.

  • Fundamentals of Quorum Sensing, Analytical Methods and Applications in Membrane Bioreactors

    • 1st Edition
    • Volume 81
    • English
    Fundamentals of Quorum Sensing, Analytical Methods and Applications in Membrane Bioreactors, Volume 81, describes the novelty of membrane bioreactors for the treatment of wastewater and the removal of specific contaminants that affect water quality or pose harm to humans. Topics of note in the updated release include Water Chemistry and Microbiology, Quorum Sensing as Bacterial Communication Language, the Effects of Quorum Sensing, Quorum Quenching, Membrane Bioreactors for Wastewater Treatment, Removal of Specific Contaminants, Microextraction Techniques, and the Determination of Quorum Sensing Chemicals. The contents of this updated volume will be appealing to a wide range of researchers as the authors of most chapters are experts in their respective fields with numerous published studies.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 69
    • English
    Advances in Organometallic Chemistry, Volume 69, contains authoritative review articles of world renowned researchers in the field of organometallic chemistry. This longstanding serial is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more, with this release focusing on topics such as C-H Activation Mediated by Main Group Inorganic and Organometallic Compounds, Transition-metals catalyzed intramolecular amination and hydroamination reactions of allenes, Green Fluorescent Protein-like and related organometallic fluorophores, Recent advances in the synthesis of C-­ S-­ bonds via metal‐catalyzed functionalization of C‐ H‐ bonds, Current mechanistic understanding of Co-catalyzed C-H functionalization, and more. The book is ideal for a wide range of researchers involved in organometallic chemistry, including synthetic protocols, mechanistic studies and practical applications.

  • Advances in Transition-Metal Mediated Heterocyclic Synthesis

    • 1st Edition
    • Daniel Sole + 1 more
    • English
    Advances in Transition-Metal Mediated Heterocyclic Synthesis provides an overview of recent catalytic reactions involving transition metals to produce heterocyclic compounds. The book is organized according to the type of transformation used to achieve the synthesis of the heterocyclic systems (mainly aza- and oxa-heterocycles). As such, it covers recent applications on the synthesis of heterocycles, also describing the details of the novel transformations in a didactic manner to motivate readers in search of new catalytic processes. The editors have included state-of-the-art strategies, including transition-metal reactions involving unsaturated systems (reactions of allenes, new gold(I)-catalyzed reactions, and Prins reaction). Chapters highlight the versatility of organopalladium chemistry dealing with carbonylative transformations, C-H activation reactions, coupling processes, and the control of the ambiphilic character of organopalladium species. Finally, the book discusses new reactions leading to heterocycles based on C-H activation processes catalyzed by other metals (Rh, Ru, Co). Written by an outstanding team of authors who are leading experts in organometallic chemistry and organic synthesis, this book is a valuable resource not only for chemists mainly focused on synthesis, but also for those interested in reaction mechanisms involving transition metals.

  • Rheology of Emulsions

    Electrohydrodynamics Principles
    • 1st Edition
    • Volume 22
    • Aleksandar M. M. Spasic
    • English
    Rheology of Emulsions, Volume 22: Electrohydrodynamics Principles studies phenomena at liquid-liquid interfaces, including finely dispersed particles or structures, in particular emulsions, double emulsions and biological cells. The book considers the forces of electrical origin that participate in the physical events at liquid-liquid interfaces, taking into account electron transfer phenomenon and electrodynamics principles. Topics covered are of interest to a broad range of scientists, researchers and graduate students with a basic knowledge of physical chemistry, electromagnetism, fluid mechanics, classical and quantum electrodynamics. The implications and applications of the material presented in the book contribute to the advanced fundamental, applied and engineering research of interfacial electroviscoelastic phenomena.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 57
    • Atta-ur Rahman
    • English
    Studies in Natural Products Chemistry, Volume 57, covers rapid developments in spectroscopic techniques and advances in high-throughput screening techniques that have made it possible to rapidly isolate and determine the structures and biological activity of natural products in new drug development. The series also covers the synthesis of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Specific sections in this release cover broad-spectrum health protection of extra virgin olive oil compounds, synthesis of cardiac steroids and their role on heart failure and cancer, and more.

  • Direct Synthesis of Metal Complexes

    • 1st Edition
    • B.I. Kharisov
    • English
    Direct Synthesis of Metal Complexes provides in-depth coverage of the direct synthesis of coordination and organometallic compounds. The work is primarily organized by methods, but also covers highly relevant complexes, such as metal-polymer coordination compounds. This updated reference discusses recent developments in cryosynthesis, electrosynthesis, and tribosynthesis (popular as it doesn’t require organic solvents), with special attention paid to ‘greener’ methodologies and approaches. Additionally, the book describes physical methods of zero-valent metal interaction with organic matter, including sputtering, ultrasonic treatment and synthesis in ionic liquids. The book presents completely new content as a follow-up to the 1999 Elsevier Science publication Direct Synthesis of Coordination and Organometallic Compounds that was edited by Dr. Garnovskii and Dr. Kharisov.

  • Synthesis of Medicinal Agents from Plants

    • 1st Edition
    • Ashish Kumar Tewari + 1 more
    • English
    Synthesis of Medicinal Agents from Plants highlights the importance of synthesizing medicinal agents from plants and outlines methods for performing it effectively. Beginning with an introduction to the significance of medicinal plants, the book goes on to provide a historical overview of drug synthesis before exploring how this can be used to successfully replicate and adapt the active agents from natural sources. Chapters then explore the medicinal properties of a number of important plants, before concluding with a discussion of the future of drugs from medicinal plants. Illustrated with real-world examples, it is a practical resource for researchers in this field. In an age of rapid environmental destruction, hundreds of medicinal plants are at risk of extinction from overexploitation and deforestation, limiting the natural resources available for active agent extraction, thereby threatening the discovery of future cures for diseases. Simultaneously, with the increasing population and advances in medical sciences, the demand for drugs is continuously increasing and cannot be met with just plants. The ability to synthetically replicate the active compounds from these plants is essential in creating an ecologically-aware, sustainable future for drug design

  • Pincer Compounds

    Chemistry and Applications
    • 1st Edition
    • David Morales-Morales
    • English
    Pincer Compounds: Chemistry and Applications offers valuable state-of-the-art coverage highlighting highly active areas of research—from mechanistic work to synthesis and characterization. The book focuses on small molecule activation chemistry (particularly H2 and hydrogenation), earth abundant metals (such as Fe), actinides, carbene-pincers, chiral catalysis, and alternative solvent usage. The book covers the current state of the field, featuring chapters from renowned contributors, covering four continents and ranging from still-active pioneers to new names emerging as creative strong contributors to this fascinating and promising area. Over a decade since the publication of Morales-Morales and Jensen’s The Chemistry of Pincer Compounds (Elsevier 2007), research in this unique area has flourished, finding a plethora of applications in almost every single branch of chemistry—from their traditional application as very robust and active catalysts all the way to potential biological and pharmaceutical applications.

  • Pericyclic Chemistry

    Orbital Mechanisms and Stereochemistry
    • 1st Edition
    • Dipak Kumar Mandal
    • English
    Pericyclic Chemistry: Orbital Mechanisms and Stereochemistry is a complete guide to the topic that is ideal for graduate students, advanced undergraduate students and researchers in organic chemistry. An introduction to molecular orbital theory and relevant stereochemical concepts is provided as background, with all four classes of pericyclic reactions discussed and illustrated with orbital picture representations. Also included are chapters on cycloadditions, the most versatile class, and electrocyclic reactions, sigmatropic rearrangements and group transfer reactions. A separate chapter on the construction of correlation diagrams is also included, emphasizing a practical, hands on approach. Author Dipak Kumar Mandal brings over 30 years of teaching experience to the topic and illuminates pericyclic chemistry with a clear and fresh perspective.

  • Catalytic Amination for N-Alkyl Amine Synthesis

    • 1st Edition
    • Feng Shi + 1 more
    • English
    Catalytic Amination for N-Alkyl Amine Synthesis provides a useful survey of this key type of reaction for chemistry researchers in academia and industry. Beginning with an introduction to amination and the development of the field, the book focuses on useful and high potential methods, such as the catalytic amination of alcohol with homogeneous and heterogeneous catalysts, the coupling reaction of olefin and amine, and the reductive amination of carbon dioxide with different reducing agents. The work also discusses two key examples of one-pot synthesis, the oxidative amination of alkane and amine and synthesis of N-alkyl amine with nitrobenzene and nitrile as starting materials. Valuable for chemists, materials scientists, chemical engineers and others, the book offers a unique overview of this growing area and its future possibilities.

  • Vicinal Diaryl Substituted Heterocycles

    A Gold Mine for the Discovery of Novel Therapeutic Agents
    • 1st Edition
    • M. R. Yadav + 2 more
    • English
    Vicinal Diaryl-Substituted Heterocycles: A Gold Mine for the Discovery of Novel Therapeutic Agents draws together all of the key information about these compounds in one place for the first time. Following an informative overview of the importance of these structures to the discovery of potential therapeutic agents, the text goes on to outline the main compound types, with each chapter focusing on the activities of a different structure. Designed to support researchers by consolidating this important information in a single, practical guide, the authors hope to encourage further advancement and development in the discovery of novel therapeutic agents. As flexible building blocks for the production of novel compounds, vicinal diaryl-substituted heterocycles are a rich source of leads for the development of new drugs. Their adaptability means that they can be used to produce structures with a broad range of attractive characteristics, and a large number of vicinal diaryl-substituted heterocyclic compounds have already been synthesized and investigated by medicinal chemists as promising lead molecules.

  • Chemical Transformations of Polymers

    • 1st Edition
    • R. Rado
    • English
    Chemical Transformations of Polymers provides information pertinent to the fundamental structure and aspects of the chemical transformation of polymers. This book examines several experiments for the chemical transformation of polymers, which start from the assumption that the reactivity of a functional group in a macromolecule has to be similar as one in a low molecular compound. Organized into 19 chapters, this book begins with an overview of the various photochromic systems that have been used in polymer chemistry. This text then examines the three types of stable polymers with unpaired electrons, including polyradical ions, neutral polyradicals, and polymeric charge transfer complexes. Other chapters consider the kinetic laws and traits of migration mechanisms of free valence in the process of decay of free radicals in polymers. The final chapter deals with the complicated reaction of the degradation of polymers induced by the presence of metal compounds. This book is a valuable resource for chemists, scientists, and physiochemical researchers.

  • Natural Products and Drug Discovery

    An Integrated Approach
    • 1st Edition
    • Subhash C. Mandal + 2 more
    • English
    Natural Products and Drug Discovery: An Integrated Approach provides an applied overview of the field, from traditional medicinal targets, to cutting-edge molecular techniques. Natural products have always been of key importance to drug discovery, but as modern techniques and technologies have allowed researchers to identify, isolate, extract and synthesize their active compounds in new ways, they are once again coming to the forefront of drug discovery. Combining the potential of traditional medicine with the refinement of modern chemical technology, the use of natural products as the basis for drugs can help in the development of more environmentally sound, economical, and effective drug discovery processes. Natural Products & Drug Discovery: An Integrated Approach reflects on the current changes in this field, giving context to the current shift and using supportive case studies to highlight the challenges and successes faced by researchers in integrating traditional medicinal sources with modern chemical technologies. It therefore acts as a useful reference to medicinal chemists, phytochemists, biochemists, pharma R&D professionals, and drug discovery students and researchers.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 56
    • Atta-ur Rahman
    • English
    Studies in Natural Products Chemistry, Volume 56 covers rapid developments in spectroscopic techniques, also presenting advances in high-throughput screening techniques, including the new potential to isolate and determine the structures and biological activity of natural products and their applications in the field of new drug development. This ongoing series covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

  • Nuclear and Radiochemistry

    • 2nd Edition
    • Jozsef Konya + 1 more
    • English
    Nuclear and Radiochemistry, Second Edition, is a comprehensive and thorough reference that features the latest developments in the field, especially in radionuclide production, nuclear medicine and the application of natural radiotracers. Drawing on 40 years of experience in teaching and research, this revised edition explains the basic principles and applications of the primary areas of nuclear and radiochemistry. This new edition features completely revised chapters, in addition to 40 new illustrations plus case studies woven throughout the text. It will be helpful to students and researchers in chemistry, chemical engineering, environmental sciences and specialists working in all fields of radiochemistry. The field of nuclear and radiochemistry is wide-reaching, with results having functions and use across a variety of disciplines. Separate chapters cover each main area of recent radiochemistry. This includes nuclear medicine and chemical aspects of nuclear power plants, namely the problems of nuclear wastes and nuclear analysis (both bulk and surface analysis), with the analytical methods based on the interactions of radiation with matter. Furthermore, special attention is paid to thermodynamics of radio-isotope tracer methods, the very diluted system (carrier-free radioactive isotopes) and the principles of chemical processes with unsealed radioactive sources.

  • NMR Spectroscopy Using Liquid Crystal Solvents

    • 1st Edition
    • JW Emsley + 1 more
    • English
    NMR Spectroscopy using Liquid Crystal Solvents covers the importance of using a liquid crystal solvent in NMR to derive nuclear dipolar spin-spin coupling constants. This book is composed of ten chapters, and begins with a brief description of the features and benefits of liquid crystal in NMR spectroscopic analysis. The succeeding chapters deal with the mode of operation of nuclear spin Hamiltonian for partially oriented molecules and the analysis of NMR spectra of partially oriented molecules, as well as the determination of rigid molecule structure. These topics are followed by discussions on internal motion studies, NMR spectra from quadpolar nuclei, and the anisotropy in nuclear spin-spin coupling. The final chapters review the theoretical and experimental studies on the anisotropy in chemical shifts, nematic rotation, and the nuclear magnetic double resonance. This book will prove useful to analytical chemists.

  • Sampling and Analysis of Environmental Chemical Pollutants

    A Complete Guide
    • 2nd Edition
    • E. P. Popek
    • English
    Sampling and Analysis of Environmental Chemical Pollutants, A Complete Guide, Second Edition promotes the knowledge of data collection fundamentals and offers technically solid procedures and basic techniques that can be applied to daily workflow solutions. The book’s organization emphasizes the practical issues facing the project scientist. In focusing the book on data collection techniques that are oriented toward the project objectives, the author clearly distinguishes the important issues from the less relevant ones. Stripping away the layers of inapplicable or irrelevant recommendations, the book centers on the underlying principles of environmental sampling and analytical chemistry and summarizes the universally accepted industry practices and standards. This Guide is a resource that will help students and practicing professionals alike better understand the issues of environmental data collection, capitalize on years of existing sampling and analysis practices, and become more knowledgeable and efficient in the task at hand.

  • C-Furanosides

    Synthesis and Stereochemistry
    • 1st Edition
    • Peter Goekjian + 3 more
    • English
    Carbon analogs of carbohydrates, dubbed C-glycosides, have remained an important and interesting class of mimetics, be it in natural product synthesis, for pharmacological applications, as conformational probes, or for biological studies. C-Furanosides: Synthesis and Stereochemistry provides a much-needed overview of synthetic and stereochemical principles for C-furanosides: analogs of a 5-membered ring carbohydrate glycoside (furanoside), in which the anomeric oxygen has been replaced with a carbon. While our understanding of conformational behavior and of stereoselective synthesis in 6-membered ring compounds is quite good, our ability to predict the conformation of 5-membered ring compounds, or to predict the stereochemical outcome of a given reaction, remains anecdotal. Through a comprehensive review of literature approaches to the different C-furanoside stereoisomers, as well as an interpretation of the outcome in terms of a reasonable number of stereochemical models, C-Furanosides: Synthesis and Stereochemistry enables the reader to determine the best approach to a particular C-glycoside compound, and also hopes to provide a certain level of rationalization and predictability for the synthesis of new systems.

  • Artemisinin-Based and Other Antimalarials

    Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them
    • 1st Edition
    • Guoqiao Li + 3 more
    • English
    Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology.

  • Inhaled Pharmaceutical Product Development Perspectives

    Challenges and Opportunities
    • 1st Edition
    • Anthony J. Hickey
    • English
    Inhaled Pharmaceutical Product Development Perspectives: Challenges and Opportunities describes methods and procedures for consideration when developing inhaled pharmaceuticals, while commenting on product development strategies and their suitability to support regulatory submission. It bridges the gap between the aspirations of scientists invested in new technology development and the requirements that must be met for any new product. The book brings together emerging analytical and inhalation technologies, providing perspectives that illuminate formulation and device design, development, regulatory compliance, and practice. Focusing on underlying scientific and technical principles known to be acceptable from the current regulatory perspective, this monograph will remain useful as a high-level guide to inhaled product development for the foreseeable future.

  • Doping, Performance-Enhancing Drugs, and Hormones in Sport

    Mechanisms of Action and Methods of Detection
    • 1st Edition
    • Anthony C. Hackney
    • English
    Doping, Performance-Enhancin... Drugs, and Hormones in Sport: Mechanisms of Action and Methods of Detection examines the biochemistry and bioanalytical aspects of performance-enhancin... drugs (PEDs) and other questionable procedures used by athletes to enhance performance. The book informs the specialist of emerging knowledge and techniques and allows the non-specialist to grasp the underlying science and current practice of the discipline. With clear and compelling language appropriate for a broad spectrum of readers, this book provides background on prevalence, types of agents, their actual or supposed benefits, and their negative effects on health. The technical aspects of detection are discussed, followed by a discussion of why detection is a problematic and still-evolving science. To facilitate comprehension, each chapter is organized in a uniform way with six sections: (1) standard medical uses, (2) why the drugs are used by athletes, (3) biological mechanism of action, (4) what research says about efficacy in improving performance, (5) major health side effects from use and abuse in sport, and 6) concluding key points.

  • Infrared and Raman Spectroscopy

    Principles and Spectral Interpretation
    • 2nd Edition
    • Peter Larkin
    • English
    Infrared and Raman Spectroscopy, Principles and Spectral Interpretation, Second Edition provides a solid introduction to vibrational spectroscopy with an emphasis on developing critical interpretation skills. This book fully integrates the use of both IR and Raman spectroscopy as spectral interpretation tools, enabling the user to utilize the strength of both techniques while also recognizing their weaknesses. This second edition more than doubles the amount of interpreted IR and Raman spectra standards and spectral unknowns. The chapter on characteristic group frequencies is expanded to include increased discussions of sulphur and phosphorus organics, aromatic and heteroaromatics as well as inorganic compounds. New topics include a discussion of crystal lattice vibrations (low frequency/THz), confocal Raman microscopy, spatial resolution in IR and Raman microscopy, as well as criteria for selecting Raman excitation wavelengths. These additions accommodate the growing use of vibrational spectroscopy for process analytical monitoring, nanomaterial investigations, and structural and identity determinations to an increasing user base in both industry and academia.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 55
    • Atta-ur Rahman
    • English
    Studies in Natural Products Chemistry, Volume 55 covers rapid developments in spectroscopic techniques, also presenting advances in high-throughput screening techniques, including the new potential to isolate and determine the structures and biological activity of natural products and their applications in the field of new drug development. This ongoing series covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

  • Frontiers and Advances in Molecular Spectroscopy

    • 1st Edition
    • Jaan Laane
    • English
    Frontiers and Advances in Molecular Spectroscopy once again brings together the most eminent scientists from around the world to describe their work at the cutting-edge of molecular spectroscopy. Much of what we know about atoms, molecules and the nature of matter has been obtained using spectroscopy over the last one hundred years or so. Going far beyond the topics discussed in Jaan Laane’s earlier book on the subject, these chapters describe new methodologies and applications, instrumental developments and theory, which are taking spectroscopy into still new frontiers. The robust range of topics once again demonstrates the wide utility of spectroscopic techniques. New topics include ultrafast spectroscopy of the transition state, SERS/far-uv spectroscopy, femtosecond coherent anti-Stokes Raman spectroscopy, high-resolution laser induced fluorescence spectroscopy, Raman spectroscopy and biosensors, vibrational optical activity, ultrafast two-dimensional spectroscopy, biology with x-ray lasers, isomerization dynamics and hydrogen bonding, single molecule imaging, spectra of intermediates, matrix isolation spectroscopy and more.

  • Recent Advances in Aminocatalyzed Cascade Reactions

    • 1st Edition
    • Vincent Coeffard + 2 more
    • English
    Recent Advances in Aminocatalyzed Cascade Reactions addresses the recent advances in asymmetric aminocatalyzed cascade transformations, including both the methodological aspects and the applications in the multi-step synthesis of biorelevant compounds. The most relevant synthetic methods merging several aminocatalytic activation modes (enamine, iminium, dienamine, trienamine…) are presented. The authors include selected examples of multi-step synthesis towards biorelevant molecules, incorporated to outline the synthetic potential of aminocatalyzed cascade reactions.

  • Laboratory Statistics

    Methods in Chemistry and Health Sciences
    • 2nd Edition
    • Anders Kallner
    • English
    Laboratory Statistics: Methods in Chemistry and Health Science, Second Edition, presents common strategies for comparing and evaluating numerical laboratory data. In particular, the text deals with the type of data and problems that laboratory scientists and students in analytical chemistry, clinical chemistry, epidemiology, and clinical research face on a daily basis. This book takes the mystery out of statistics and provides simple, hands-on instructions in the format of everyday formulas. Spreadsheet shortcuts and functions are included, along with many simple worked examples. This book is a must-have guide to applied statistics in the lab that will result in improved experimental design and analysis. This thoroughly revised second edition includes several new sections, more examples, and all formulas in Excel code.

  • Particles at Interfaces

    Interactions, Deposition, Structure
    • 2nd Edition
    • Volume 20
    • Zbigniew Adamczyk
    • English
    Particles and Interfaces: Interaction, Deposition, Structure, Volume 20, Second Edition unifies particle and protein adsorption phenomena by presenting recent developments in this growing field of nanoscience. While experimental data is available in vast quantities, there is a deficit in quality interpretation of that data. This title provides such information, emphasizing the basic physics behind practical problems, thus empowering the reader to estimate relevant effects. The book includes solved problems of particle transport under non-linear conditions and their relevance to predicting protein adsorption, including an entirely new chapter devoted to polyelectrolyte and protein adsorption at solid/liquid and solid/gas interfaces.

  • Organosilicon Compounds

    Experiment (Physico-Chemical Studies) and Applications
    • 1st Edition
    • Vladimir Ya Lee
    • English
    Organosilicon Compounds: Experiment (Physico-Chemical Studies) and Applications, volume 2, also contains two parts. In its first part, Experiment (Physico-Chemical Studies), the application of modern instrumental tools (such as X-ray crystallography, 29Si NMR spectroscopy, UV-Photoelectron Spectroscopy, and other methods) for assessing the structures of organosilicon compounds is described. The second part, Applications, reviews the current research in the field of material science, specifically the use of organosilicon compounds in synthetic chemistry directed towards the creation of new materials. Organosilicon Compounds: From Theory to Synthesis to Applications provides a comprehensive overview of this important area of organic and organometallic chemistry, dealing with compounds containing carbon–silicon bonds. This field, which includes compounds that are widely encountered in commercial products such as in the fabrication of sealants, adhesives, and coatings, has seen many milestone discoveries reported during the last two decades. Beginning with the theoretical aspects of organosilicon compounds’ structure and bonding, the book then explores their synthetic aspects, including main group element organosilicon compounds, transition metal complexes, silicon cages and clusters, low-coordinate organosilicon derivatives (cations, radicals, anions, multiple bonds to silicon, silaaromatics), and more. Next, readers will find valuable sections that explore physical and chemical properties of organosilicon compounds by means of X-ray crystallography, 29Si NMR spectroscopy, photoelectron spectroscopy, and other methods. Finally, the work delves into applications for industrial uses and in many related fields, such as polymers, material science, nanotechnology, bioorganics, and medicinal silicon chemistry.

  • Molecular and Laser Spectroscopy

    Advances and Applications
    • 1st Edition
    • V.P. Gupta
    • English
    Molecular and Laser Spectroscopy: Advances and Applications provides students and researchers with an up-to-date understanding of the fast-developing area of molecular and laser spectroscopy. Editor V.P. Gupta has brought together the eminent scientists on a selection of topics to develop a systematic approach, first covering basic principles needed to understand each cutting-edge technique and application. This book acts as a standard reference for advanced students of molecular and laser spectroscopy and as a graduate text for new entrants in the field. The book covers a wide range of applications of molecular and laser spectroscopy in diverse areas ranging from materials to medicine and defence, biomedical research, environmental monitoring, forensic investigations, food and agriculture, and chemical, pharmaceutical and petrochemical processes. Researchers and scientific personnel in these fields will learn the latest techniques in order to put them to practical use in their work.

  • Strategies and Tactics in Organic Synthesis

    • 1st Edition
    • Volume 13
    • Michael Harmata
    • English
    Strategies and Tactics in Organic Synthesis, Volume 13, provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, this classic provides stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project present the excitement of conception, the frustration of failure and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project. Readers will be educated, challenged and inspired by these accounts, which portray the idea that triumphs do not come without challenges. This innovative approach also helps illustrate how challenges to further advance the science and art of organic synthesis can be overcome, driving the field forward to meet the demands of society by discovering new reactions, creating new designs and building molecules with atom and step economies that provide functional solutions to create a better world.

  • Reactivity of P-H Group of Phosphorus Based Compounds

    • 1st Edition
    • Kolio D. Troev
    • English
    Reactivity of P-H Group of Phosphorus Based Compounds bridges the gap between inorganic and organic phosphorus compounds, providing a basis to explore the myriad possibilities for synthesis of novel low and high molecular phosphorus-containin... compounds. It covers well-documented reactions in detail, including: tautomerization, oxidation, reduction, alkylation, oxidation coupling, addition reaction to: carbon-carbon multiple bonds, Schiff base, isocyanates, nitriles, epoxides; addition to carbonyl group, Kabachnik- Fields reaction, cross-coupling reaction and more. In an accessible style complete with synthetic routes and figures, the resource then covers the reactivity of multiple P-H group members: phosphines, phosphine oxides, hypophosphorus acid, H-phosphinic acids and polys(alkylene H-phosphonate). This valuable coverage supports the advancement of research and applications in this area for scientists solving a scientific problem or starting a variety of new projects, such as a new reaction for the synthesis of biologically active compounds, new methods of polymer synthesis or a new methodology for polymer modification.

  • Progress in Heterocyclic Chemistry

    • 1st Edition
    • Volume 29
    • Gordon Gribble + 1 more
    • English
    Progress in Heterocyclic Chemistry (PHC), Volume 29, is the latest in this annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year’s literature on heterocyclic chemistry and articles on new developing topics of particular interest to heterocyclic chemists. The highlight chapters in Volume 29 are all written by leading researchers in their field and these chapters constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2016. As with previous volumes in the series, Volume 29 will enable academic and industrial chemists, and advanced students, to keep abreast of developments in heterocyclic chemistry in a convenient way.

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