Skip to main content
Elsevier

Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • Synthesis of Epoxides

    • 1st Edition
    • Navjeet Kaur
    • English
    Synthesis of Epoxides explores different techniques for making epoxides, both old and new, and delves into the growing field of heterocyclic chemistry. The book presents a variety of methods that will help readers figure out which one best suits their specific needs. Diazo compounds are important synthetic intermediates in organic synthesis, but because of their unpredictable, explosive nature and toxicity their unique reactivity has not been fully exploited and their use at large scale has been avoided. Readers, including students in chemistry, will learn about different methods and important information, allowing them to evaluate which method is most suitable in particular cases.The synthetic usefulness of diazo compounds cannot be overlooked despite their danger. Because of their ylide and 1,3-dipole nature, the diazo compounds have a unique reactivity. The diazo compounds can be utilized for various different conversions including S-ylide-assisted epoxidation, cyclopropanation, or aziridination reactions. This book describes the new and classic methods for the synthesis of epoxides and covers an important and rapidly growing branch of heterocyclic chemistry.

  • Advances in Physical Organic Chemistry

    • 1st Edition
    • Volume 58
    • English
    Advances in Physical Organic Chemistry, Volume 58 is the latest release in this definitive resource for authoritative reviews of work in physical organic chemistry. It aims to provide a valuable source of information not only for physical organic chemists applying their expertise to both novel and traditional problems but also for non-specialists across diverse areas. Its hallmark is quantitative, molecular level understanding of phenomena across a diverse range of disciplines. Sample chapters in this new release include Coacervate formation and the partitioning of molecules into these phases and The area of artificial signal transduction systems.

  • Natural and Synthetic Hydrogels

    Rational Design, Synthesis and Biomedical Applications
    • 1st Edition
    • Ravin Narain
    • English
    Natural and Synthetic Hydrogels: Rational Design, Synthesis and Biomedical Applications provides acomprehensive text on hydrogels and their biomedical uses, covering both fundamental and applied aspects of hydrogels. Hydrogels are three-dimensional network of cross-linked polymers or particles that contain a large amount of water. They have received tremendous attention for applications in biomedicines, which has led to significant progress in the design and engineering of the hydrogels to meet the needs for such applications.The book covers the recent developments that have been made in this field, including new applications of hydrogels, providing a new and fresh overview of hydrogels and their applications.Natural and Synthetic Hydrogels: Rational Design, Synthesis and Biomedical Applications is valuableto upper level undergraduate and graduate students, researchers, and progressors teaching fundamental and applied aspects of hydrogels.

  • Progress in Heterocyclic Chemistry (PHC)

    • 1st Edition
    • Volume 36
    • R. Alan Aitken + 1 more
    • English
    Progress in Heterocyclic Chemistry (PHC), Volume 36 is the latest in this annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year’s literature on heterocyclic chemistry and articles on new and developing topics of particular interest to heterocyclic chemists. The highlight chapters in this volume are all written by leading researchers in their fields, and these chapters constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2023.As with previous volumes in the series, this update will enable academic and industrial chemists, and advanced students, to keep abreast of developments in heterocyclic chemistry in a convenient way.

  • Edible Nanomaterials

    • 1st Edition
    • Volume 107
    • English
    Edible Nanomaterials, Volume 107 highlights new advances in the field of medicine, with this new volume presenting interesting chapters on topics including Plant-derived edible nanoparticles and their therapeutic utilities, Endogenous and artificial carbon dots from edible sources: Synthesis, applications in biomedicine and uses as fluorescent analytical probes, Nano-edible coatings, Panoramic Exploration of Comestible Nanomaterials for enhancement of food quality and safety and their environmental impact, Nanonutraceuticals: Exploring the nanoencapsulation route for bioactive delivery, Synthesis of Edible Nanoparticles for Food Applications, and much more.Additional sections explore Plants as Emerging Nano Factories: A Green Approach, Edible Nanomaterials for Biomedical Devices, Therapeutics Agents, and Regenerative Tissue Engineering, Plants as Nanofactories, and Synthesis Strategies of Edible Nanoparticles: Advancements and Perspectives.

  • Annual Reports in Medicinal Chemistry: Roadmaps

    • 1st Edition
    • Volume 62
    • English
    Annual Reports in Medicinal Chemistry: Roadmaps, Volume 62 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. This release provides a compendium of information on newly approved drugs and compounds entering late-stage clinical trials, making it a valuable resource for graduate students pursuing research in medicinal chemistry

  • Sample Handling and Trace Analysis of Pollutants

    Innovations to Determine Organic Contaminants
    • 2nd Edition
    • Damia Barcelo + 1 more
    • English
    Sample Handling and Trace Analysis of Pollutants: Innovations to Determine Organic Contaminants, Second Edition, reviews the latest technologies and challenges in trace analysis of environmental pollutants, from selecting the right approach to performing the analytical procedures to measuring and reporting the results. This updated and revised edition presents the latest techniques of the past decade, such as high-resolution mass spectrometry, biosensors and imaging techniques. Important tools for problem-solving in the determination of environmental pollutants are discussed in detail. This book also covers emerging pollutants in the environment, such as nanomaterials, microplastics, metabolites and/or transformation products and antimicrobial resistances. This book is an excellent resource for postgraduate students, environmental chemists and analytical chemists, as well as those working in environmental laboratories, laboratories of official environmental controls, universities and the private sector.

  • Human Microbiome Drug Targets

    Modern Approaches in Disease Management
    • 1st Edition
    • Genevieve Dable-Tupas + 3 more
    • English
    Human Microbiome Drug Targets: Modern Approaches in Disease Management presents fundamental information on the human microbiome, looking into the relationship between the microbiome and how it changes with specific diseases. Delving into the multifaceted roles of the microbiome in health and disease, the book's chapters discuss the role of the human microbiome in the pathophysiologic understanding of relevant diseases or disorders and their management. As changes in the human microbiome can provide clues to the probable cause and effect of diseases or disorders, as well as the impacts of therapy or intervention, this book is a welcomed addition to the existing research.Explaining how a better understanding of the microbiome and its impact on health and disease can pave the way for future discoveries leading to better health outcomes, this book will be of interest to drug developers, medicinal chemists, microbiologists, infectious disease specialists, biochemists, and students.

  • Method Development in Analytical HPLC

    • 1st Edition
    • Serban C. Moldoveanu + 1 more
    • English
    Method Development in Analytical HPLC presents the essential information for understanding the process of developing an HPLC method of analysis. It includes foundational information related to HPLC, as well as discussion of sample types, the properties of analytes and matrices in the samples, and sample preparation. The core of the book describes the best ways for approaching method development in various types of HPLC and the criteria for method optimization and validation. This book provides clear guidance for adopting analytical methods from the literature and describes the development of original methods with selection of the suitable type of HPLC, of specific columns, mobile phase, and detection techniques with an emphasis on the use of mass spectrometry for detection, as well as optimization and validation of the chosen analytical method. The book includes useful details on method development for specific types of chromatography such as RP-HPLC, HILIC, ion exchange, size exclusion, and chiral.Method Development in Analytical HPLC also includes information about green chemistry in analytical methods, computer assisted method development, and other key contemporary aspects of the subject.

  • Rearrangements with Migration to Electrophilic Heteroatomic Centers

    Timeless Classics in Organic Synthesis
    • 1st Edition
    • Sosale Chandrasekhar
    • English
    Rearrangements with Migration to Electrophilic Heteroatomic Centers: Timeless Classics in Organic Synthesis covers the basic principles and synthetic applications of a critically important class of organic reactions that date back to the founding period of organic chemistry. These reactions are not only of historical and pedagogical interest, but also have great practical value to this day, being inevitable in any strategy concerning the introduction of nitrogen and oxygen functionality. The book is made up of three parts, dealing with the Beckmann reaction, the Hoffmann family of reactions and the Baeyer-Villiger reaction.The book strikes a balance between delineation and exhaustiveness, with up-to-date refences for readers requiring in-depth coverage. Relevant industrial applications, including pharmaceutical processes, are included.

  • RAS Drug Discovery

    Past, Present and Future
    • 1st Edition
    • Adrian Gill + 1 more
    • English
    KRAS Drug Discovery: Past, Present and Future is a comprehensive overview of the state-of-the-art medicinal chemistry approaches towards targeting the formerly undruggable oncogene, KRAS. It includes Seminal medicinal chemistry case histories of KRASG12C inhibitors such as Sotorosib, the first approved KRASG12C inhibitor for NSCLC, alongside the latest advances towards identification of in vivo tools and development candidates targeting KRAS G12D, KRAS G13C and other mutations. The book also provides the reader with a comprehensive overview of the in vitro assay systems, in vivo pharmacology xenograft models and chemical biology tools available to characterize small molecule inhibitors of KRAS.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 63
    • English
    Progress in Medicinal Chemistry, Volume 63 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Specific chapters in this release include Harnessing conformational drivers in drug design, Recent Advances in the Medicinal Chemistry of Heterobifunctional Derivatives for Protein Homeostasis, and A Decade of Antimalarial Drug Discovery: New Targets, Tools and Molecules.

  • The Alkaloids

    • 1st Edition
    • Volume 92
    • English
    The Alkaloids: Chemistry and Biology, Volume 92, the newest release in a series that has covered the topic for more than 60 years, discusses key aspects of alkaloid chemistry, biology and pharmacology. Sections in this release include chapters on Renieramycin-type Bis-1,2,3,4-tetrahyd... Marine Natural Products, Structure, activity, and biosynthesis of indolactam alkaloids, and The Chemistry and Biology of Pyrazole and Indazole Alkaloids.

  • Computational Insights into Catalytic Transformations

    • 1st Edition
    • Volume 75
    • Maria Biosca
    • English
    Computational Insights into Catalytic Transformations, Volume 75 in the Advances in Catalysis series, highlights new advances in the field, with this new volume presenting interesting chapters on topics including Quantum Chemical Investigations on Electrophilic F/CF3/SCF3 Transfer Hypervalent Iodine Reagents, Combining DFT and experimental studies in enantioselective catalysis. From rationalization to prediction, Molecular Modelling of encapsulation and reactivity within metallocages, On the role of computational chemistry in the design of artificial metalloenzymes, and Computational Modelling of Catalytic Oxidation Reactions with H2O2 promoted by transition metal-substituted polyoxometalates.

  • Advances in Prodrugs

    Design and Therapeutic Applications
    • 1st Edition
    • Claudiu Trandafir Supuran + 2 more
    • English
    Advances in Prodrugs: Design and Therapeutic Applications provides a versatile tool in prodrug design and development as well as a concrete perspective on clinical and preclinical studies currently available on prodrugs. The first part of this book discusses different chemical classes of prodrugs, with particular emphasis on metabolic pathways and mechanisms involved in the activation of their functional groups. The second part of the book covers therapeutic applications of prodrugs against the most discussed diseases, providing detailed discussion on recent achievements in the field. This book offers researchers involved in drug discovery key criteria for the successful development of prodrug-based therapeutic tools.Prodrugs are inactive drug precursors which undergo different chemical transformation by metabolic processes to provide pharmacologically active compounds. Prodrugs include a broad range of structurally diverse molecules employed for the treatment of several diseases.

  • Specification of Drug Substances and Products

    Development and Validation of Analytical Methods
    • 3rd Edition
    • Christopher M. Riley + 1 more
    • English
    Specification of Drug Substances and Products: Development and Validation of Analytical Methods, Third Edition contains chapters discussing the unique requirements for the universal critical quality attributes, as well as the specific tests required to characterize and control different types of products, ranging in complexity from small molecules in immediate release oral dosage forms to complex products such as drug-antibody conjugates and mRNA-based products. This substantially expanded revision of the second edition will serve as practical comprehensive reference for scientists, managers, educators, and consultants involved in the development and regulation of pharmaceutical products.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 83
    • Atta-ur Rahman
    • English
    Studies in Natural Products Chemistry, Volume 83 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects.With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

  • Electrochemical Potassium Storage

    Principles, Materials, and Technological Development
    • 1st Edition
    • Yang XU
    • English
    Electrochemical potassium storage explores the principles, materials, and technological developments of a variety of battery technologies based on electrochemical potassium storage. It covers the principles of potassium-ion batteries (organic and aqueous electrolytes), potassium metal batteries, potassium-sulfur (selenium) batteries, and potassium-oxygen batteries, as well as the development of the electrode materials of these batteries and the understanding of electrochemical cell operations.Batteries using potassium ions as the charge carrier to store energy operate via different electrochemical processes and have different features of materials electrochemistry compared to lithium-based batteries. Thus, battery technologies based on electrochemical potassium storage exhibit different performance strengths, potentially having diverse market applications. This is particularly important for the search for environmentally and economically sustainable alternatives to conventional lithium-ion batteries in a wide range of applications.This book presents the state-of-the-art development of potassium-based batteries and in-depth discussion on their structure-to-perform... relationships.

  • Oxazole, Isoxazole, Benzoxazole-Based Drug Discovery

    • 1st Edition
    • Erum Akbar Hussain + 2 more
    • English
    Oxazole, Isoxazole, Benzoxazole Based Drug Discovery offers complete coverage of oxazole and related molecules, both from natural and synthetic origin, with a focus on the reaction mechanisms, and medicinal, pharmacokinetic and computational aspects. New and contemporary methods of synthesis are discussed, with a special focus on green, environment-friendly procedures. Discussion of stereochemical studies, particularly on natural molecules, are included. Computational chemistry has emerged as an integral tool for drug discovery, hence this book explains how the drug candidate is established as suitable for clinical trials with the help of molecular docking and virtual screening modeling.This book offers a broad range of recent developments and detailed coverage of synthesis and biological activities of the drugs, and is an ideal reference guide to researchers working in organic and medicinal chemistry.

  • Earth-Abundant Transition Metal Catalyzed Reactions

    • 1st Edition
    • Volume 74
    • English
    Earth-Abundant Transition Metal Catalyzed Reactions, Volume 74 in the Advances in Catalysis series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Chapters in this new release include in Chiral Iron Complexes for Asymmetric Catalysis, Recent advances in Ni-catalyzed Functionalization of Strong C-O and C-H Bonds, Low-valent Molecular Cobalt Complexes for Reductive Chemistry, Iron-catalyzed group-transfer reactions with hypervalent iodine reagents, and Iron Porphyrins for Mediating Atom Efficient C–C Bond Formations.

  • Novel Treatments of Strong Correlations

    • 1st Edition
    • Volume 90
    • English
    Novel Treatments of Strong Correlations, Volume 90 in the Advances in Quantum Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics covered include Coupled Cluster, Stochastic CC, NOFT, Breaking the Symmetry Dilemma : Capturing Strong-Correlations by Restoration of Broken Symmetry Solutions, Flexible wavefunctions, Electronic Coupling to Optical Cavity Modes, Multireference Perturbation Theories Based on the Dyall Hamiltonian, The GW Approximation: A Quantum Chemistry Perspective, Geminals, and more.

  • Inorganic Chemistry in Spain

    • 1st Edition
    • Volume 84
    • English
    The editors of the volume Inorganic Chemistry in Spain have intended to achieve a collection of some chapters featuring the work of Spanish experts in Inorganic Chemistry, each one having specific expertise in some field. Areas that cover theory, classical coordination compounds, new materials, supramolecular assemblies, mechanisms of reactions, magnetism, organometallic complexes, and catalysis are included. In all cases, a special relevance is given to a deep understanding of the behavioural properties of the compounds featured, not only to their mere preparation methodologies, which had been historically related to classical Inorganic Chemistry.

  • Organic Synthesis

    • 5th Edition
    • Michael Smith
    • English
    **2025 Textbook and Academic Authors Association (TAA) Textbook Excellence "Texty" Award Winner**Organic Synthesis, Fifth Edition provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, providing them with critical working knowledge of basic reactions, stereochemistry, and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature.There have been advancements in organic reactions, particularly organometallic reactions, and there is a need to show how these advancements have influenced current organic synthesis. The goal is to revise and update the reaction examples taken from the synthesis literature from 2017 to 2023. The reactions illustrate those used most often in modern organic synthesis, but these new examples will show their current relevance. Where new approaches and reactions have been developed for organic synthesis, examples have been added as new material.

  • Visible Light-Driven Organic Synthesis

    • 1st Edition
    • Goutam Brahmachari
    • English
    Visible Light-Driven Organic Synthesis covers the recent cutting-edge investigations in the field of visible light– driven organic synthesis in a single comprehensive volume. It provides information on rigorously selected reaction schemes and covers new reactions and new methods under visible light photocatalysis. It enlists more than 100 important synthetic strategies/methodolo... with particular emphasis on useful reactions for organic synthesis under the mild reaction conditions reported in recent times involving carbon–carbon (C–C) and carbon–heteroatom bond–forming reactions, resulting in a wide spectrum of chemical compounds, providing an outstanding source of information concerning industrial applications.The chapters are classified based on various photocatalysts that have found direct applications in organic synthesis by carrying out different kinds of organic reactions. Each chapter is dedicated to a particular photocatalyst, and each selected reaction is dealt with in a compact manner through point-wise discussion under distinct subheadings covering the reaction type, reaction conditions, bond-forming information, reaction strategy involved, general reaction scheme, examples of representative entries with chemical structures and physical properties, a suggested plausible mechanism, critical views, and literature. In addition, visible light–mediated self-sensitized organic transformations that took place without any external photocatalysts have also been covered.This book is immensely helpful to chemistry students, teachers, researchers, academicians, and chemical/ agrochemical industry people to access the latest information and advances on visible light–driven organic synthesis developments.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 112
    • English
    Annual Reports on NMR Spectroscopy, Volume 112 presents the latest release in a series that has established itself as a premier resource for both specialists and non-specialists interested in new techniques and applications pertaining to NMR spectroscopy. Chapters in this new release include Artificial Neural Networks in Magnetic Resonance Relaxometry, Tumor extracellular pH mapping using electron paramagnetic resonance: Techniques and applications, and Recent Affordable Permanent Magnet Configurations and related technologies for Portable Nuclear magnetic resonance (NMR)/Magnetic Resonance Imaging (MRI) for medical care.Magnetic resonance now has a history exceeding 70 years. Not only has the range of applications of magnetic resonance-based techniques grown exponentially but so too has the literature. Consequently, a distillation and synthesis of the literature is in itself an extremely important research tool, providing an efficient means to take newcomers to the research frontiers and keeping experienced researchers aware of contemporary practice. Since 1968 Annual Reports on NMR Spectroscopy been at the vanguard of reviewing the magnetic resonance literature. Annual Reports on NMR Spectroscopy covers magnetic resonance in all its forms, including theory, experiment, applications, and interconnections with other techniques. It also provides the opportunity to make coherent aspects of magnetic resonance that were scattered and opaque. Historical articles including obituaries are also welcomed.Potential authors are encouraged to consult with the Serial Editor.William S. PriceWestern Sydney University, NSW, Australiaw.price@wes...

  • Specialized Plant Metabolites as Cosmeceuticals

    • 1st Edition
    • Deepika Kathuria + 2 more
    • English
    Specialized Plant Metabolites as Cosmeceuticals presents a comprehensive guide to traditional medicinal plants that are used in the field of cosmetics. Chapters cover geographical distribution, extraction of key components from each plant, traditional uses, pharmacognostic characteristics, phytochemistry, pharmacology, toxicology, and future prospects. This book will be a valuable asset for researchers and graduate students of chemistry, botany, biotechnology, microbiology, cosmetology and the pharmaceutical sciences. As medicinal plants are a rich source of a variety of bioactive secondary metabolites, their wide range of pharmacological applications as antibiotics, antifungals, anticancer agents, and antimicrobial and antiviral applications provide new and exciting avenues.In addition, they have great implications for the food, pharmaceutical, cosmetics and personal care product industries. Secondary metabolites also ecofriendly, cost effective, biocompatible, and cause less side effects as compare to synthetic compounds.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 82
    • Atta-Ur Rahman
    • English
    Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.Studies in Natural Products Chemistry covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 82
    • English
    Advances in Organometallic Chemistry, Volume 82, the latest release in this longstanding serial, is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more. Chapters in this new release include Pd-catalysis: a useful tool in the field of polymer synthesis. Recent advances and applications, Modern Mechanistic Approaches for the Depolymerization of Commodity Plastics via Homogeneous Metal Catalysis, Functionalization of fullerenes by transition metal catalyzed cyclization reactions, and Synergistic Metal-Ligand Reactivity in Half-Sandwich Complexes of Fe, Co, and Ni for Bond Activation and Catalysis.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 111
    • English
    Annual Reports on NMR Spectroscopy, Volume 111 presents the latest release in a series that has established itself as a premier resource for both specialists and non-specialists interested in new techniques and applications pertaining to NMR spectroscopy. Chapters in this new release include Electrophoretic NMR, Traceability and uncertainty in NMR measurements, Quantitative NMR Spectroscopy, Advances in Non-Uniform Sampling NMR, NMR spectroscopy of natural and synthetic fibers, Characterization of transition alkane complexes, and Recent applications of low field NMR to membrane science.Magnetic resonance now has a history exceeding 70 years. Not only has the range of applications of magnetic resonance-based techniques grown exponentially but so too has the literature. Consequently, a distillation and synthesis of the literature is in itself an extremely important research tool, providing an efficient means to take newcomers to the research frontiers and keeping experienced researchers aware of contemporary practice. Since 1968 Annual Reports on NMR Spectroscopy been at the vanguard of reviewing the magnetic resonance literature. Annual Reports on NMR Spectroscopy covers magnetic resonance in all its forms, including theory, experiment, applications, and interconnections with other techniques. It also provides the opportunity to make coherent aspects of magnetic resonance that were scattered and opaque. Historical articles including obituaries are also welcomed.Potential authors are encouraged to consult with the Serial Editor.William S. PriceWestern Sydney University, NSW, Australiaw.price@wes...

  • Machine Learning and Artificial Intelligence in Chemical and Biological Sensing

    • 1st Edition
    • Jeong-Yeol Yoon + 1 more
    • English
    Machine Learning and Artificial Intelligence in Chemical and Biological Sensing covers the theoretical background and practical applications of various ML/AI methods toward chemical and biological sensing. No comprehensive reference text has been available previously to cover the wide breadth of this topic. The book's editors have written the first three chapters to firmly introduce the reader to fundamental ML theories that can be used for chemical/biosensing. Subsequent chapters then cover the practical applications with contributions by various experts in the field.Sections show how ML and AI-based techniques can provide solutions for: 1) identifying and quantifying target molecules when specific receptors are unavailable 2) analyzing complex mixtures of target molecules, such as gut microbiome and soil microbiome 3) analyzing high-throughput and high-dimensional data, such as drug screening, molecular interaction, and environmental toxicant analysis, 4) analyzing complex data sets where fingerprinting approach is needed This book is written primarily for upper undergraduate students, graduate students, research staff, and faculty members at teaching and research universities and colleges who are working on chemical sensing, biosensing, analytical chemistry, analytical biochemistry, biomedical imaging, medical diagnostics, environmental monitoring, and agricultural applications.

  • Analytical Applications of Graphene Oxide

    • 1st Edition
    • Volume 106
    • English
    Analytical Applications of Graphene Oxide, Volume 106 in the Comprehensive Analytical Chemistry series, presents timely topics in this area of study. Chapters in this new release include 2. Surface Modifications of Graphene Oxide Nanomaterials for Analytical Applications, Analytical techniques for the characterization of graphene oxide, Perspectives of graphene oxide in separation science, Features of graphene oxide-based membranes in water purification, Graphene oxide nanocomposites for the removal of inorganic species, Graphene oxide nanocomposites as promising adsorbents for removal of organic pollutants, Graphene oxide-based metal nanocomposites for colorimetric sensing applications, Graphene oxide-based fluorescence analytical methods for bioassays, and much more.Additional sections delve into Graphene oxide in molecular biology approaches for nucleic acid detection, Analytical applications of graphene oxide-based hydrogels, Magnetic graphene oxide in analytical science, Applications of Magnetic graphene oxide in water decontamination, Graphene oxide nanocomposites in electroanalytical tools for assaying of organic and biomolecules, Graphene oxide in electroanalytical tools for the detection of inorganic species, and much more.

  • Chemometrics

    Data Treatment and Applications
    • 1st Edition
    • Fabiano André Narciso Fernandes + 2 more
    • English
    Chemometrics: Data Treatment and Applications demonstrates best practices for treating real-world analytical instrument data and how to apply chemometrics to this data. Rather than focusing on the mathematical theory involved in chemometrics, the book is meant for the industrial chemist, academics, and advanced students that want to use chemometrics in practice. Case studies on several applications are presented. Unlike existing literature, this book focuses on best practices, practical realities, and challenges when treating data, rather than on the mathematical theory. It also provides basic information on chemometrics and the best practices used to treat data from different analytical instruments.The book is written primarily for analytic chemists as practitioners in analytical laboratories and other industries. It will also be useful to academics and graduate, masters and postdoc students chiefly working in analytical chemistry who want to improve the practical aspects of their research activities.

  • Metal-Organic Frameworks in Analytical Sample Preparation and Sensing

    • 1st Edition
    • Verónica Pino + 2 more
    • English
    Metal-organic Frameworks in Analytical Sample Preparation and Sensing presents all the areas of applications of metal-organic frameworks in analytical sample preparation. Metal-organic frameworks are crystalline coordination polymers with robust and stable crystal structures, high synthetic tunability, and interesting properties for their use in analytical applications, including their detailed use as sorbents in miniaturized-extract... procedures and as components in sensors.This book also provides important information about the synthesis and characterization of these materials, with useful tips written by experts on the subject with respect to their conditioning, handling, and recycling. Their outstanding properties, adsorptive capabilities, and structural diversity are also highlighted. This will help experts in the field to select the proper metal-organic framework for a particular analytical application.

  • Women’s Contribution to F-element Science

    • 1st Edition
    • Volume 65
    • English
    Women’s Contribution to F-element Science, Volume 65 in the Handbook on the Physics and Chemistry of Rare Earths series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Rare-Earth Upconversion Luminescence and Its Applications: From Molecular, to Nano and Micro Scales, Control of 4f complexes luminescence and magnetism with (organic) photoswitches, Lanthanide-Based Responsive MRI Probes, Luminescent solar concentrators: current and future applications in smart cities, Lanthanide Chalcogenide Precursors: from luminescence to nanoparticle synthesis, Helical coordination complexes of rare earths and their luminescent properties, and much more.Other chapters cover Environmental and molecular facets of uranyl(V) and uranium(V) chemistry, Uranium dendrites in molten salt electrorefining, Impact of synthesis routes on the optical performance of upconverting and NIR emitting lanthanide-doped nanoparticles, Lanthanide complexes for luminescence, therapy, and sensing, Versatile core/shell luminescent nanoparticles for biophotonic studies, and 4f-Metal ions in single molecule magnet systems.

  • Fused Pyranones

    Multifaceted Building Blocks for Molecular Diversity
    • 1st Edition
    • Vishnu Ji Ram + 2 more
    • English
    Fused Pyranones: Multifaceted Building Blocks for Molecular Diversity covers the synthesis and chemical reactivity of fused pyranone ring systems, such as coumarin, isocoumarin, chromonone, chroman-4-one, and others, as well as their applications in the fields of drug discovery and material sciences. Mechanisms of the chemical reactions are covered, along with the steps to formation of final products. This book is ideal for organic, medicinal and material chemists and researchers working to build target compounds for pharmaceuticals and materials, as well as those working in food supplements, perfumery, and cell and animal imaging.

  • Herbal Formulations, Phytochemistry and Pharmacognosy

    • 1st Edition
    • Mital Kaneria + 1 more
    • English
    Herbal formulations, Phytochemistry and Pharmacognosy combines the principles of natural medicines with refined modern technology that helps the development of more ecofriendly, better effective, easily available, and affordable drug discovery process.The drug discovery process accelerates the design of new leads for various life-threatening diseases. Natural medicines have been an integral part of drug discovery process, and these not only play a major role as a template for the drug discovery but also offer holistic approach for better management of various diseases.The main purpose of this book is to provide the classical and applied knowledge in drug discovery and broadly cover the related aspects such as herbal formulations, phytochemistry and pharmacogenetic research.

  • Green Approaches in Medicinal Chemistry for Sustainable Drug Design

    Methods
    • 2nd Edition
    • Volume 2
    • Bimal Banik
    • English
    Green Approaches in Medicinal Chemistry for Sustainable Drug Design: Methods, Second Edition reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context on the growth of green chemistry in relation to drug discovery, the book identifies a range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure, and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global experts, the book encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists, and more.This volume covers synthesis methods following green chemistry principles, contributing to sustainability by saving energy, using lesser toxic reagents/solvents/ca... and environmentally benign sources, including plants and agricultural materials.

  • The Chemistry of Hyperpolarized Magnetic Resonance Probes

    • 1st Edition
    • Volume 12
    • Eul Hyun Suh + 1 more
    • English
    The Chemistry of Hyperpolarized Magnetic Resonance Probes, Volume Seven focuses on the chemical aspects of hyperpolarized NMR/MRI technology, with synthesis and characterizations of labeled compounds discussed from a practical point-of-view. A brief overview of the various hyperpolarization techniques are given, with the optimization of hyperpolarization conditions and the determination of critical parameters such as polarization level and T1 relaxation values described. A practical guide on the in vivo applications of hyperpolarized compounds in small animals is also included.

  • Green Approaches in Medicinal Chemistry for Sustainable Drug Design

    Applications
    • 2nd Edition
    • Volume 1
    • Bimal Banik
    • English
    Sustainable and Green Approaches in Medicinal Chemistry: Applications, Second Edition reveals essential context on the growth of green chemistry in relation to drug discovery, identifying a broad range of practical techniques and useful insights and revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure, and increase the environmental benignity of the entire drug discovery process. The book encourages the growth of green medicinal chemistry and supports medicinal chemists, drug discovery researchers, pharmacologists, and all those in related fields across both academia and industry in integrating these approaches into their own work.This volume includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods.

  • Photochemistry and Photophysics of Earth-Abundant Transition Metal Complexes

    • 1st Edition
    • Volume 83
    • English
    Photochemistry and Photophysics of Earth-Abundant Transition Metal Complexes, Volume 83 in the Advances in Inorganic Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Radioluminescence of Copper(I) Clusters, Photophysics and Photochemistry of Chromium(III) Complexes (Molecular Rubies), Chromic behaviors of luminescent copper(I) complexes, Long-lived photoluminescence in group 4 metal complexes enabled by ligand-to-metal charge transfer, Photoactive MOFs for CO2 Activation utilizing Earth Abundant Metals, and more.Other sections cover Earth Abundant Metal Complexes for Optoelectronic Applications, Photoactive metal to ligand charge transfer excited states in 3d6 and 3d8 complexes, Ligand-to-metal charge-transfer excited states in d0 transition-metal complexes: Investigations into the photochemistry and photophysics of emissive titanocenes, Ultrafast dynamics in photoactive copper complexes from optical and Xray methods, and Photophysical properties of Ni(II) complexes and some copper(I) and zinc(II) complexes.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 144
    • English
    Advances in Heterocyclic Chemistry, Volume 144 highlights new advances in the field, with this volume presenting chapters on Metal free C-H functionalization of aromatic and non-aromatic heterocyclic systems, Divergent Total Synthesis of Indolizidine-, Quinolizidine-, and Decahydroquinoline-t... Poison-frog Alkaloids, A perspective on the synthetic potential of bio-based building blocks for heterocyclic chemistry, Recent advances in the synthesis of 3,3-disubstituted oxetanes, and Pyrrole-based chemosensors: Recent trends.

  • The Alkaloids

    Chemistry and Biology
    • 1st Edition
    • Volume 91
    • English
    The Alkaloids: Chemistry and Biology, Volume 91, the newest release in a series that has covered the topic for more than 60 years, discusses key aspects of alkaloid chemistry, biology and pharmacology. Sections in this release include chapters on Recent Progress in the Chemistry of Naphthylisoquinoline Alkaloids.

  • Wave Optics in Infrared Spectroscopy

    Theory, Simulation, and Modeling
    • 1st Edition
    • Thomas G. Mayerhöfer
    • English
    Wave Optics in Infrared Spectroscopy starts where conventional books about infrared spectroscopy end. Whereas the latter are based on the Bouguer-Beer-Lambert law, the cornerstones of this book are wave optics and dispersion theory.This gap between both levels of theory is bridged to allow a seamless transition from one to the other. Based on these foundations, the reader is able to choose which level of theory is adequate for the particular problem at hand. Advanced topics like 2D correlation analysis, chemometrics and strong coupling are introduced and viewed from a wave optics perspective. Spectral mixing rules are also considered to better understand spectra of heterogeneous samples. Finally, optical anisotropy is examined to allow a better understanding of spectral features due to orientation and orientational averaging. This discussion is based on a 4 x 4 matrix formalism, which is used not only to simulate and analyze complex materials, but also to understand vibrational circular dichroism from a (semi-) classical point of view.Wave Optics in Infrared Spectroscopy is written as a tool to reunite the fragmented field of infrared spectroscopy. It will appeal to chemists, physicists, and chemical/optical engineers.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 81
    • English
    Advances in Organometallic Chemistry, Volume 81 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Specific chapters cover Recent Advances in the Catalytic Applications of NHC-Early Abundant Metals (Fe, Mn, Co) Complexes, A Guide to Non-Carbonyl, Non-Isocyano Organometallic Chemistry of Technetium-99 from Discovery to 2023, and Cyclopentadienyl, Amidinate (CPAM) Complexes of Groups 4 - 6 Transition Metals.

  • Comprehensive Chirality

    • 2nd Edition
    • Janine Cossy
    • English
    Comprehensive Chirality, Second Edition is the definitive ten-volume reference, offering a thorough exploration of chiral research and application. This extensively updated edition features 121 new chapters and 70 revised ones, focusing on the latest advancements in chiral research across synthesis, catalysis, analytical chemistry, and bioactive compound synthesis. Edited by a world-class editorial board, with contributions from leading experts, Comprehensive Chirality, Second Edition bridges theoretical principles with practical applications, making it an invaluable resource for advanced students, researchers, and professionals. Key highlights include:- Innovative Reactions and Methods: advanced diastereo- and enantioselective techniques for controlling stereogenic centers in complex natural products and pharmaceuticals.- Chiral Auxiliaries and Modern Reagents: transformative uses of chiral auxiliaries and cutting-edge reagents such as hypervalent iodide.- Catalytic Methodologies: comprehensive coverage of C-C bond formation, emphasizing transition metals, biocatalysis, and multicatalysis.- Asymmetric Photochemistry: light-induced asymmetric transformations.- Olefin Functionalization and Cycloaddition: asymmetric oxidation and reduction methods.- Biocatalysis and Enzyme Engineering: in-depth analysis of enzyme design and engineering as powerful synthesis catalysts.- Industrial Applications: practical insights into asymmetric synthesis for industrial applications, illustrated through recent case studies.- Spectroscopic Techniques: updated spectroscopic methods for separating and analyzing enantiomers.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 81
    • Atta-Ur Rahman
    • Atta-Ur Rahman
    • English
    Studies in Natural Products Chemistry, Volume 81 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts on fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects.With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

  • Sustainable Quality Improvements for Isotope Dilution in Molecular Ultratrace Analyses

    Fitness for Purpose, Performance-Based Criteria, and Measurement Uncertainty
    • 1st Edition
    • Yves Tondeur
    • English
    Sustainable Quality Improvements for Isotope Dilution in Molecular Ultratrace Analyses: Fitness for Purpose, Performance-Based Criteria, and Measurement Uncertainty uses a novel Sustainable Quality Improvement (SQI) framework with the aim of helping to re-introduce much needed flexibility and restore accountability and integrity necessary for developing confidence in products obtained with these specialty assays. The book can also be used as a comprehensive reference text for data and information on matrix-specific target analytes detection/quantitati... limits, and measurement of uncertainties for planning purposes, congeners profiles, multi-phasic, multi-component and multi-analyte samples processing flow charts, and useful definitions of the underlying technology-relevant terminologies.The SQI framework around which the book is constructed paves the way for the innovative technological solutions described in the book and is powered by three key elements: Fitness for Purpose (Data Quality Objectives), Performance-Based Measurement System (flexibility, latitude), and Measurement Uncertainty (accountability). Together, they facilitate the development and validation of advanced methodologies to resolve many of the contemporary issues associated with continuously evolving and demanding regulatory requirements. A stronger focus on effective performance feedback is demonstrated to help laboratories rethink their own approach to quality improvements.

  • Metal Organic Frameworks

    Fundamentals to Advanced
    • 1st Edition
    • Bhawana Jain + 3 more
    • English
    Metal Organic Frameworks: Fundamentals to Advanced offers a substantial and complete treatment of published results. The book includes a summary of current research, along with an in- depth explanation of Metal organic frameworks (MOFs) and applications in this versatile area. Metal organic frameworks (MOFs) are structured frameworks made up of metal ions and organic molecules. These materials are similar to sponges and can absorb, retain and remove molecules from their pores. As a result, metal-organic frameworks (MOFs) are the most rapidly evolving substances in chemistry with the highest surface areas due to their well-ordered pore structure.The exciting and vast surface area allows for more chemical reactions and molecule adsorption, hence this new resource provides the newest updates on the topics covered.

  • Applications of Green Nanomaterials in Analytical Chemistry

    • 1st Edition
    • Volume 105
    • English
    Applications of Green Nanomaterials in Analytical Chemistry, Volume 105 in the Comprehensive Analytical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters, including Introduction (Modern Perspective of analysis with Green NMs), Green Nanomaterials based Sample Preparation techniques, Molecularly imprinting polymer nanomaterials-based sensing/detection and separation/removal of estrogenic compounds from environmental samples, Green Nanomaterials in Extraction Techniques, Green Nanomaterials in Sample Pre-treatment Processes, Lab on Chip with Green Nanomaterials, and much more.Other chapters cover Emerging green carbon dots: Opto-electronic and Morpho-structural properties for sensing applications, Green Nanomaterials based Nanosensors, Green Nanomaterials in Electroanalytical Chemistry, BioSensors with Green Nanomaterials, Green synthesis of metal based nanomaterials and their sensing application, Analytical Sensing with Green Nanomaterials, Lateral flow assay with green nanomaterials, Green nanomaterials for sorbent-based extraction techniques in food analysis, Green Nanomaterials for Chromatographic Techniques, Membranes with Green Nanomaterials, Conclusion: Future of Analytical Chemistry

  • Recent Advances in Organometallic Chemistry

    Synthetic, Mechanistic and Medicinal Perspective
    • 1st Edition
    • Azaj Ansari + 1 more
    • English
    Recent Advances in Organometallic Chemistry: Synthetic, Mechanistic and Medicinal Perspective highlights recent advancements in the field of organometallic chemistry. Containing essential information for researchers and advanced-level students, especially those working in chemical synthesis, the book describes the role of organometallic compounds in different combinations in organic synthesis and pharmaceuticals as well as discussing spectral, magnetic and sensing features of the compounds. Including the role of computational investigations towards the mechanistic study of biomimic complexes in catalytic transformation reactions, the book provides a large number of examples along with their leading applications in other fields.Each chapter covers basic strategies, which are illustrated along with examples of the latest advancements in the field and in-depth explanations.

Related subjects