
Supercritical Fluid Chromatography and Extraction
- 2nd Edition - November 1, 2025
- Editors: Caroline West, Colin F. Poole
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 3 3 4 6 9 - 6
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 3 4 7 0 - 2
Supercritical fluid chromatography (SFC) is a rapidly developing laboratory technique for the separation and identification of compounds in mixtures. Recent, significant… Read more

New to This Edition
This new edition details recent advances and applications of supercritical fluids in sample prep, instrumental analysis, and process-scale, including SFE, making it a comprehensive resource for both techniques. Further enhancements to this edition include:
- Expanded section on SFC theory to include gradient elution
- A new chapter on general detectors for SFC
- Enhanced method development coverage, with focus on gradient elution practices
- Includes multidimensional SFC, SFC × SFC, and LC-SFC
- Features comprehensive information on accelerated solvents, comparing solvent and extraction techniques.
- Highlights environmental monitoring and analysis applications of SFE.
- Covers method development for SFC and SFE across instrument platforms and process scale for both techniques
- Combines comprehensive coverage of both techniques in one volume
- Edited and authored by leading chromatography and extraction experts
- Contains over 200 figures and tables for clarity and key concept retention
- Showcases applications in environmental monitoring, food, natural products, forensic science, petrochemicals, pharmaceuticals, and bioanalysis
1. Core concepts and milestones in the exploitation of supercritical fluids in separation science
2. Theory of supercritical fluid chromatography
3. Stationary phases for supercritical fluid chromatography
4. Stationary phases for the separation of stereoisomers by supercritical fluid chromatography
5. Co-solvents and mobile phase additives in supercritical fluid chromatography
6. Method development in supercritical fluid chromatography
7. Instrument platforms for supercritical fluid chromatography
8. General detectors for supercritical fluid chromatography
9. Mass spectrometric detection in supercritical fluid chromatography
10. Multidimensional supercritical fluid chromatography
11. Method validation in supercritical fluid chromatography
12. Sample preparation for supercritical fluid chromatography
13. Supercritical fluid chromatography of amino acids and peptides
14. Supercritical fluid chromatography of lipids
15. Supercritical fluid chromatography of stereoisomers
16. Applications of supercritical fluid chromatography in environmental analysis
17. Applications of supercritical fluid chromatography in food analysis
18. Applications of supercritical fluid chromatography in forensic analysis
19. Applications of supercritical fluid chromatography in natural product analysis
20. Applications of supercritical fluid chromatography in the analysis of petrochemicals
21. Applications of supercritical fluid chromatography in the pharmaceutical industry
22. Applications of supercritical fluid chromatography in bioanalysis
23. Theory for preparative supercritical fluid chromatography
24. Instrument platforms for preparative and process scale supercritical fluid chromatography
25. Applications of preparative and process scale supercritical fluid chromatography in the pharmaceutical industry
26. Applications of preparative and process scale supercritical fluid chromatography of natural products
27. Core concepts and fundamentals of supercritical fluid extraction
28. Instrument platforms for supercritical fluid extraction
29. Pressurized hot-water and accelerated solvent extraction
30. Supercritical fluid extraction of essential oils
31. Supercritical fluid extraction of lipids and bio-oils
32. Supercritical fluid extraction of agricultural products
33. Supercritical fluid extraction of petroleum products
34. Applications of Supercritical fluid extraction for environmental analysis
- Edition: 2
- Published: November 1, 2025
- Language: English
CW
Caroline West
CP