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Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • Advances in Amino Acid Mimetics and Peptidomimetics

    • 1st Edition
    • Volume 1
    • A. Abell
    • English
    Peptidomimetics are compounds which mimic the biological activity of peptides while offering the advantages of increased bioavailability, biostability, bioefficiency, and bioselectivity against the natural biological target of the parent peptide. Examples of peptidomimetics have been isolated as natural products, synthesized as libraries from novel subunits, and designed on the basis of X-ray crystallographic studies and through an intricate knowledge of the biological mode of action of natural peptides. They offer challenging synthetic targets and are increasingly important medicinal agents and biological probes. As a consequence, peptidomimetics embrace much of what is modern medicinal and organic chemistry. This volume highlights some recent and exciting developments in the area.

  • Advances in DNA Sequence-specific Agents

    • 1st Edition
    • Volume 3
    • M. Palumbo
    • English
    In this volume the entire focus is devoted to the macromolecule target specificity of DNA interactive developmental therapeutic agents of current interest. A brief introduction to DNA interactive anticancer agents is included for readers who may benefit from an overview surrounding the developments that have contributed to our general understanding of this field. The following nine chapters have been carefully chosen so that they describe topics which are at the forefront of development in DNA-targeted cancer chemotherapy. Issues that have been addressed include the mechanisms of selective DNA topoisomerase I and II poisoning by antitumor agents (Chapters 1 and 2), sequence-specific recognition of DNA by groove-binding drugs and drug-conjugates (Chapters 3 and 4), recent developments in nitrogen mustard alkylating agents and their potential use for antibody-directed enzyme-prodrug therapy (Chapter 5), nonclassical platinum anticancer complexes, including dinuclear and trans-platinum derivatives (Chapter 6), DNA cleaving antitumor chromoproteins containing reactive enediyne moieties, which exhibit interesting free-radical chemistry along with selective targeting (Chapter 7), the potential of new sequence-specific antisense and antigene therapy in oncology (Chapter 8), and finally the conceivable chemotherapeutic use of mimetics of the DNA structure, obtained by substitution of the sugar-phosphate natural chain with a peptide backbone, the so-called peptide nucleic acids (Chapter 9). Important approaches being currently investigated for selective cancer treatment, such as gene therapy and immunochemotherapy, are not discussed in this volume since they fall beyond its scope.

  • Chemistry of the Elements

    • 2nd Edition
    • N. N. Greenwood + 1 more
    • English
    When this innovative textbook first appeared in 1984 it rapidly became a great success throughout the world and has already been translated into several European and Asian languages. Now the authors have completely revised and updated the text, including more than 2000 new literature references to work published since the first edition. No page has been left unaltered but the novel features which proved so attractive have been retained. The book presents a balanced, coherent and comprehensive account of the chemistry of the elements for both undergraduate and postgraduate students. This crucial central area of chemistry is full of ingenious experiments, intriguing compounds and exciting new discoveries. The authors specifically avoid the term `inorganic chemistry' since this evokes an outmoded view of chemistry which is no longer appropriate in the final decade of the 20th century. Accordingly, the book covers not only the 'inorganic' chemistry of the elements, but also analytical, theoretical, industrial, organometallic, bio-inorganic and other cognate areas of chemistry. The authors have broken with recent tradition in the teaching of their subject and adopted a new and highly successful approach based on descriptive chemistry. The chemistry of the elements is still discussed within the context of an underlying theoretical framework, giving cohesion and structure to the text, but at all times the chemical facts are emphasized. Students are invited to enter the exciting world of chemical phenomena with a sound knowledge and understanding of the subject, to approach experimentation with an open mind, and to assess observations reliably. This is a book that students will not only value during their formal education, but will keep and refer to throughout their careers as chemists.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 69
    • English
    This volume includes the third, and final, part of a trilogy on acyclonucleosides by E.S.H. El Ashry and Y. El Kilany which began in Volume 67. This chapter covers tri-, tetra-, and penta- seco-nucleosides. These compounds are of considerable interest due to their relationship to newer anti AIDS drugs. Other chapters deal with the use of organohypervalent iodine reagents in the synthesis of organic compounds, a review of the conformational analysis of saturated 6-membered oxygen containing rings, comprising the oxanes, the various dioxanes, trioxanes, and tetroxanes, and heteropentalenes with fused imidazoles of 1,2,4-triazole rings.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 70
    • English
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area--one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.

  • Synthetic and Stereochemical Aspects

    • 1st Edition
    • Volume 2
    • Philip Page
    • English
    The impact of organosulfur chemistry, especially in the areas of heterocyclic chemistry, stereocontrolled processes, and asymmetric synthesis, has led to a resurgence of interest in the field. This book is the secondin a series intended to provide coverage of topics of current interest throughout the whole range of organosulfur chemistry. Each volume is comprised of five or six chapters, each consisting of an in-depth, self-contained review in a well-defined area. This volume and its predecessor Organosulfur Chemistry, Synthetic Aspects will prove valuable references for researchers and practitioners in organic chemistry.

  • Chemistry and Biology

    • 1st Edition
    • Volume 50
    • English
    Chemistry and Biology is a celebration of the outstanding contributions to the field by Professor R.H.F. Manske, who founded the series in 1950. This special volume demonstrates the dramatic changes in alkaloidchemistry since then. It also offers a unique overview of recent developments in major areas of alkaloid chemistry and biology and looks at how these areas will develop in the future. These fourteen contributions are written by many of the leading alkaloid chemists in the world, and thus comprise a unique view of alkaloids and their contributions to the health and well-being of humankind.

  • Annual Reports in Medicinal Chemistry

    • 1st Edition
    • Volume 32
    • James A. Bristol
    • English
    Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expectedto provide the basis for entirely new future therapies.

  • Fundamentals of Inorganic Chemistry

    An Introductory Text for Degree Studies
    • 1st Edition
    • J Barrett + 1 more
    • English
    This work is a foundation course text for first and second year undergraduates in which description and understanding of inorganic chemistry are fully integrated. It covers the main underlying theoretical ideas, taking account of the level of mathematical ability among present-day students commencing university study. Each chapter provides "worked example" problems, supported by additional problem-exercises which test comprehension and serve for revision or self-study.

  • Structure and Chemistry (Part E)

    • 1st Edition
    • Volume 19
    • Atta-ur Rahman
    • English

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