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Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • Discovery of Novel Natural Products with Therapeutic Potential

    • 1st Edition
    • October 22, 2013
    • Vincent P. Gullo
    • English
    Although science has discovered effective drugs for many of the diseases that afflict mankind, many human health problems remain untreatable. The search for novel therapeutic agents is always ongoing. This book will describe some of the diverse sourcesof natural products, such as terrestrial and marine environments; and will review how research has increased knowledge of biological systems and human disease, leading to the design of targeted asssays, amenable to high volume screening.

  • Polysaccharides

    Syntheses, Modifications and Structure/Property Relations
    • 1st Edition
    • Volume 36
    • October 22, 2013
    • M. Yalpani
    • English
    This book provides the most up-to-date and comprehensive coverage of the structures and properties of polysaccharides, methods for their characterization, de novo synthesis, and modification, as well as advances in structure/function correlations. Many of these topics are summarized for the first time.A brief survey of polysaccharide structures is given highlighting the most significant advances in analytical and spectroscopic technology (NMR, MS, etc.). A chapter is devoted to glycan properties, including conformational aspects, rheological and compatibility characteristics, etc. There is a comprehensive overview of the de novo synthesis of carbohydrate polymers, the transformation of glycans into novel types of polymers, and the preparation of linear and branched polysaccharide analogues and conjugates with synthetic polymers via chemical and enzymatic approaches. The book also details the factors controlling the uniformity of substitutions in homogeneous and heterogeneous derivatization processes and the elucidation of the substitution patterns of partially modified polysaccharides, through combined spectroscopic and statistical methods.One of the important developments in the glycan field is based on the increasing demand for greater control of the functional properties of these biopolymers. The book provides a very extensive account of various types of modifications, including selective and non-selective chemical techniques, biological methods that facilitate alterations or specific functional groups and properties through the application of synthetic or degradative enzymes, and mutational or recombinant DNA techniques. The coverage extends to the control of glycan integrity and molecular weight through chemical enzymatic, physical or other methods. Electrochemical modification techniques are also discussed.A particularly up-to-date and comprehensive review is given of polysaccharide structure/property relations. Here, the effects of primary structural parameters (composition, molecular size, branching, polyelectrolyte character and non-carbohydrate substituents) are discussed, as are factors which affect glycan solubility, viscosity and gel-forming capacity. Also included are the phenomena resulting from the interactions of polysaccharides with solvents, salts, polyols, surfactants, synthetic and biological polymers. The impact of glycan structural parameters on various biological activities, such as immunological, anticoagulant, and antitumour properties, is surveyed.The book features a foreword by Dr. R.H. Marchessault, and contains almost 2,000 references to the state-of-the-art in the field, as well as an extensive subject index, over 40 tables, and 130 schemes and illustrations. It provides a wealth of valuable information for specialists in polysaccharides, biochemists, biotechnologists, enzymologists, microbiologists, organic chemists, polymer scientists, and others whose work involves these biopolymers.

  • Small Peptides

    Chemistry, Biology and Clinical Studies
    • 1st Edition
    • October 22, 2013
    • A.S. Dutta
    • H. Timmerman
    • English
    Pharmacochemistry Library, Volume 19: Small Peptides: Chemistry, Biology, and Clinical Studies focuses on the processes, reactions, properties, and characteristics of peptides, including analogues and proteases. The publication first takes a look at angiotensin II and bombesin/gastrin-rel... peptide. Topics include conformationally restricted analogues of bombesin, non-peptide antagonists of angiotensin II, receptor subtypes of angiotensin II, and bombesin/GRP antagonists and cancer. The text then elaborates on bradykinin, cholecystokinin, and enkephalin analogues. The manuscript examines luteinizing hormone releasing hormone and somatostatin. Topics include enzymic degradation of somatostatin and analogues, clinical applications of somatostatin analogues, and pharmacological and clinical studies with LHRH agonists and antagonists. The formulation of peptides and inhibitors of aspartyl proteases are also mentioned. The book is a valuable source of information for chemists, biologists, and readers interested in small peptides.

  • Isotopic Tracers in Biology

    An Introduction to Tracer Methodology
    • 3rd Edition
    • October 22, 2013
    • Martin D. Kamen
    • Louis F. Fieser + 1 more
    • English
    Isotopic Tracers in Biology: An Introduction to Tracer Methodology, Third Edition focuses on stable isotopes, structures, composition, and reactions of nitrogen and oxygen, and radioactive tracers. The book first takes a look at atomic nuclei, radioactivity, and the production of radioactive isotopes and radiation characteristics of tracer atoms. Topics include nuclear reactions, general properties of nuclei, radioactivity, target techniques and radiochemistry, and beta and gamma radiations. The text also discusses isotopic assay, radiation hazards, procedures related with sample preparation for radioactive assay, and combustion of labeled materials. The manuscript examines the biochemical, physiological, and medical aspects of tracer methodology, as well as biochemical applications, value of tracer methods for biology, intermediary metabolism, and applications to clinical research. The text also ponders on the isotopes of hydrogen, carbon, oxygen, nitrogen, phosphorus, and sulfur. Concerns include assay of deuterium and tritium, short-lived and heavy stable carbon, and oxygen, nitrogen, sulfur, and phosphorus isotopes. The publication is a dependable reference for readers interested in isotopic tracers.

  • Student's Guide to Fundamentals of Chemistry

    Brescia, Arents, Meislich, Turk
    • 4th Edition
    • October 22, 2013
    • Jo A. Beran
    • English
    Student's Guide to Fundamentals of Chemistry, Fourth Edition provides an introduction to the basic chemical principles. This book deals with various approaches to chemical principles and problem solving in chemistry. Organized into 25 chapters, this edition begins with an overview of how to define and recognize the more common names and symbols in chemistry. This text then discusses the historical development of the concept of atom as well as the historical determination of atomic weights for the elements. Other chapters consider how to calculate the molecular weight of a compound from its formula. This book discusses as well the characteristics of a photon in terms of its particle-like properties and defines the wavelength, frequency, and speed of light. The final chapter deals with the fundamental components of air and the classification of materials formed in natural waters. This book is a valuable resource for chemistry students, lecturers, and instructors.

  • Ion Transport

    • 1st Edition
    • October 22, 2013
    • David Keeling + 1 more
    • English
    Ion Transport is a collection of papers from the Smith Kline & French Research "Symposium on Ion Transport" held in Cambridge, on April 12-14, 1989. These papers focus on the plasma membrane, particularly on the three main classes of transporters, namely, pumps, exchangers, and channels. Some papers discuss the different experimental approaches from electrophysiological and ion flux measurements through pharmacology, molecular biology, electrostatics, and computer modeling. Other papers discuss the P-type cation pump, a class of ATP-driven ion pumps, which is determined from its subunit composition and from the results of the hydrolysis of ATP. Several papers explain the techniques used in ion channels and their modulation. These techniques can be used in the voltage-gated Na+ channel or in permeation mechanisms. Other papers examine the transport proteins involved in the physiology of ion transport. Ions and fluid transport relate to, at the molecular level, how ions cross membranes. A minimum model, in conjunction with theoretical perspective, can describe the mechanism by which ions move through channels. This collection can prove beneficial for biochemists, micro-biologists, cellular researchers, and academicians involved in the study of cellular biology or biophysics.

  • Hazard Assessment of Chemicals

    Current Developments
    • 1st Edition
    • October 22, 2013
    • Jitendra Saxena
    • English
    Hazard Assessment of Chemicals: Current Developments, Volume 2 contains authoritative articles, which provide a comprehensive review and evaluation of important information on chemical spills, and presents case studies that show the applications of methods and approaches to environmental and health hazard assessment of chemicals. The book is comprised of five subject reviews and two case studies of chemical spills. Experts tackle subjects on the use of simulation models to determine pollutant behavior and pollutant migration; use of microcosms to assess chemical effects on the properties of aquatic ecosystems; and metabolism and disposition of potentially hazardous chemicals in maternal-embryonic/f... systems. Epidemiological approaches to chemical hazard assessment and a review of The National Toxicology Program (NTP) in the Department of Health and Human Services are also presented. Environmentalists, ecologists, toxicologists, public safety officers and workers, and those concerned with the health effects of chemical agents in the environment will find this text invaluable.

  • Analytical Applications of 1,10-Phenanthroline and Related Compounds

    International Series of Monographs in Analytical Chemistry
    • 1st Edition
    • October 22, 2013
    • Alfred A. Schilt
    • R. Belcher + 1 more
    • English
    Analytical Applications of 1,10-Phenanthroline and Related Compounds, Volume 32 presents the significance of 1,10-phenanthroline in chemical analysis. This book discusses the varied other uses for 1,10-phenanthroline or of the distinctive advantages afforded by certain related compounds. Organized into eight chapters, this volume begins with an overview of the planar structure of 1,10-phenanthroline. This text then examines the relative inertness of phenanthroline towards chemical reaction other than chelation or salt-formation, which is an essential asset in its analytical applications. Other chapters consider the coordination chemistry of phenanthroline and bipyridine in detail. This book discusses as well the metal ions chelated, the features of the chelates, and the influence of substituent groups or other changes in the ligands on the properties of the chelates. The final chapter examines the scientific and commercial uses for 1,10-phenanthroline and related compounds, which have increased in number and importance. This book is a valuable resource for analytical chemists.

  • Silicon in Organic Synthesis

    Butterworths Monographs in Chemistry and Chemical Engineering
    • 1st Edition
    • October 22, 2013
    • Ernest W. Colvin
    • Patrick Perlmutter + 2 more
    • English
    Silicon in Organic Synthesis provides an introduction to the organic chemistry of silicon. This book places particular emphasis on the concept of silicon as a “ferryman,” mediating the transformation of one wholly organic molecule into another. The book begins by reviewing the discovery and development of organosilicon compounds. This is followed by separate chapters on the physical properties of organosilicon compounds; the preparation of α-metallated organosilanes, which play a key role in preparative organosilicon chemistry; migration/rearrangem... reactions of silicon; the preparation and chemistry of vinylsilanes, allylsilanes, arylsilanes, and organosilyl metallic compounds. Subsequent chapters cover the synthesis of compounds such as alkene, alkynylsilanes, allenylsilanes, silylketenes, alkyl silyl ethers, acyloxysilanes, and silyl enol ethers. This book aims to serve as a timely introduction to organic chemistry for students and practitioners of synthetic organic chemistry, as well as provide a source of useful information and possibly of new ideas to those already experienced in the area.

  • Survey of Progress in Chemistry

    Volume 1
    • 1st Edition
    • Volume 1
    • October 22, 2013
    • Arthur F. Scott
    • English
    Survey of Progress in Chemistry, Volume 1 explores the principles common to all chemistry that undergo major developments and modifications, including high-temperature reactions, chemical valence, metallocenes, and redox reactions. This volume is divided into seven chapters, and begins with the presentation of some analytical methods as research tools in chemistry. The next chapters deal with the thermodynamic generalization of high-temperature reactions; molecular structural studies that are incompatible with the Lewis theory; and the general chemical aspects of metallocenes. These topics are followed by discussions on the significance of oxidation-reaction mechanisms in organic chemistry and some remarkable chemical processes occurring in the living systems. The last chapter describes the structure and reaction mechanisms of Grignard reagent. This book is of value to chemistry teachers and students.

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