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Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • Sulphones in Organic Synthesis

    • 1st Edition
    • Volume 10
    • N S. Simpkins
    • Patrick Perlmutter
    • English
    Over the last twenty years the use of sulphones in organic synthesis has increased dramatically, the synthetic repertoire of sulphones having been developed to such an extent as to rival the carbonyl functionality for versatility. Not only have sulphones been employed in a great many synthetic methodologies, enabling the preparation of a vast array of functionalised products, but the sulphone group has also proved to be of enormous value in many of the most demanding and sophisticated total syntheses carried out in recent years. This book describes in detail all of the important sulphone chemistry employed in organic synthesis, ranging from the well-established sulphone-mediated methods to less familiar sulphone reactions and very recent discoveries of synthetic potential.
  • Natural, Metal, Fiber, and Macromolecular Carcinogens

    Structural Bases and Biological Mechanisms
    • 1st Edition
    • Yin-Tak Woo + 2 more
    • English
    Chemical Induction of Cancer: Structural Bases and Biological Mechanisms, Volume IIIC: Natural, Metal, Fiber, and Macromolecular Carcinogens covers structure-carcinogen... relationships of carcinogenic mycotoxins, carcinogenic substances generated by plants, carcinogenic metals and metalloids, and foreign-body carcinogens. The book discusses the metabolism and mechanism of carcinogenic action, physicochemical properties, other biological activities (principally mutagenicity and teratogenicity), modification of carcinogenic activity, formation and environmental significance. The text also describes the carcinogenic water-soluble high polymers and explores the intriguing problems of the carcinogenic effect of osmotic imbalance in tissue microenvironment, as well as of spontaneous malignant transformation occurring in cell cultures in vitro. Studies on tumor induction and carcinogenesis modification by nonviral nucleic acids, by nucleases, proteases, histones, and by antigenic stimulation as well as by antibodies are also considered. The book further tackles tumor-released factors as possible modifiers of carcinogenesis. The text will prove invaluable to chemists and people involved in cancer research.
  • Pharmaceutical and Biomedical Applications of Liquid Chromatography

    • 1st Edition
    • Volume 1
    • W.J. Lough + 2 more
    • English
    This volume reflects the changes that have taken place in the pharmaceutical industry over the last ten years, most notably the increased importance attached to the question of chirality, the growing influence of biotechnology and the need for more rigorous documentation and validation of analytical methods and procedures.The first part of this book deals with the application of new technology to pharmaceutical and biomedical analysis, reflecting the present needs for increased speed, sensitivity and selectivity in the analysis of drugs. The second chapter provides an overview of capillary electophoresis, which represents one of the most inportant analytical developments to impact directly on pharmaceutical development in recent years. Although not a chromatographic technique, capillary electrophoresis was considered too important to be ignored.Over the last 25 years, liquid chromatography has grown into a mature analytical technique and many of the fundamental issues concerned with retention and separation are well defined. The practitioners of modern liquid chromatography spend as much time in the development of techniques for sampling handling and automation as they do in the development of the separation. Therefore, Part Two of this book describes some of the recent advances in the areas of sample handling and the isolation of compounds from biological samples, including solid phase extraction, restricted access media for direct injection, coupled column technology and microdialysis. Similarily, Part Three contains two chapters concerned with liquid chromatographic methods for the isolation of drug substances, peptides and proteins from other complex media.The pharmaceutical industry and the process of drug development are highly regulated and the increasing importance that the regulatory authorities attach to validation has had a significant impact on the analytical techniques used for the analysis of drugs. Although this has increased the workload of analysts in the pharmaceutical industry, it has also improved the quality of analytical methods used in the support of investigational and new drug applications as well as the quality of methods published more recently in the literature. Consequently, Part Four of this volume describes approaches to the optimization and validation of liquid chromatography methods for the analysis of drugs in the bulk form, in pharmaceutical formulations and biological fluids.
  • Plastics Materials

    • 6th Edition
    • J A Brydson
    • English
    The sixth edition of this classic reference work continues to provide a balanced and comprehensive overview of the nature, manufacture, structure, properties, processing and applications of commercially available plastics materials. Aiming to bridge the gap between theory and practice, it enables scientists to understand the commercial implications of their work as well as providing technologists with a theoretical background.Early chapters describe the history and nature of plastics and explain the relationship of chemical structure and properties. Preparation, structure, properties processing and applications of each class of plastics materials are then considered separately. New chapters have been added on materials selection and special polymers, including biodegradable and electroconductive polymers and thermoplastic elastomers. In addition many new plastics materials have been added throughout the text and more information has been included on testing methods and data. The sections on production/consumpti... statistics has also been completely updated. Reviews of previous editions:It's a genuine milestone in reference works...and the book is a 'must' for anyone concerned with the selection, preparation, compounding or processing of these materials' - British Plastic and Rubber 'This latest edition maintains the high standard set previously... The book s a 'must' for both student and practising technologists' - Plastics Materials'The fourth edition of John Brydson's book carries on the splendid traditions of the previous three. As a reference book for a laboratory, sales office or student's bedroom, it is unrivalled in its comprehensive of the history, chemistry and technology of plastics'. - Reinforced Plastics 'As a reference book on the subject it is unique for its depth in such a compact form, yet allied to that it is so eminently readable. It is a working chemist's book for a working chemist.' - Journal of the Oil and Colour Chemists Association 'This is one of the most comprehensive reference books in its class.' - Polymer News, March 1996
  • The Chemistry of Inorganic Ring Systems

    • 1st Edition
    • Volume 14
    • R. Steudel
    • English
    The present volume considers the most recent developments in the chemistry of cyclic inorganic and organoelement compounds. Nineteen of the 22 chapters are based on invited and other lectures presented at the 6th International Symposium on Inorganic Ring Systems held in Berlin on August 18-22, 1991.Main group compounds dominate the content from boron via carbon, silicon, germanium, tin, nitrogen, phosphorus and arsenic, to sulfur and selenium. The book is organized by element, moving from left to right in the main groups of the Periodic Table, followed by one chapter each on bonding and nomenclature of ring molecules. The list of contributors comprises distinguished scientists from 8 countries.
  • Carbon-13 NMR of Flavonoids

    • 1st Edition
    • Volume 39
    • P.K. Agrawal
    • English
    This detailed treatise is written for chemists who are not NMR spectroscopists but who wish to use carbon-13 NMR spectroscopy. It shows why measurement of carbon-13 NMR is needed and explains how the method can - or should - be used for rapid characterization of flavonoids, one of the most diverse and widespread groups of natural constituents.The first part of the book presents background information and discussion of the essential aspects of flavonoids and carbon-13 NMR spectroscopy and demonstrates its significant role in the revision of several earlier established chemical structures. It discusses various one- and two-dimensional NMR spectroscopic techniques and other relevant experimental methodologies for the interpretation of spectral details which enable individual resonance lines to be associated with the appropriate carbons in a molecule. The second part provides a comprehensive coverage of the carbon-13 chemical shifts of various classes and subclasses of flavonoids. It also illustrates how to utilize carbon-13 data to gain information for the determination of the nature, number and site of any substituent in flavonoids. Vital information for the differential and complete structure elucidation of the various classes of flavonoids by carbon-13 NMR shielding data is described in-depth in the third part of the book.The book will be welcomed by all those working in natural product chemistry who will appreciate the non-mathematical approach and the fact that such a wealth of theoretical and practical information has been assembled in a single volume.
  • Organometallic Syntheses

    • 1st Edition
    • Volume 4
    • R. Bruce King
    • English
    Over 160 detailed and tested procedures for the preparation of specific organometallic compounds are given in Volume 4. Part I contains procedures for the synthesis of 76 types of transition metal organometallic compounds, and Part II procedures for the synthesis of 85 nontransition metal organometallic compounds. In both parts, the editors have sought to include procedures that give the safe, reliable synthesis of organometallic compounds that can lay some claim to significance in current chemical research. This significance may be based on various factors such as: (a) the synthesis describes the formation of an unusual or less common structural type; (b) the compound prepared is a useful intermediate in other syntheses; (c) the compound is a model reagent for investigating the mechanisms of various fundamental or industrial processes, such as the Fischer-Tropsch reaction; (d) the compound is a useful reagent in organic synthesis; and (e) the techniques employed in the synthesis of the compound are unusual and worthy of further application, such as metal-atom and electrochemical procedures.Each specific or generalized procedure is organized into the following sections: an Introduction which discusses the available procedures and the reasons guiding the choice of the one selected; a Procedure section which strives to describe the modus operandi, the safety concerns and pitfalls in the preparation; a Properties section that offers further physical and chemical data on the product and, where appropriate, indications of how the compounds can be employed in research; and a Reference section which gives both leading literature citations and supplemental comments on the procedure.Research laboratories in organometallic chemistry, organic chemistry, inorganic chemistry and molecular catalysis have in this book a rich source of information on the preparation of organometallic compounds.
  • Spin Labeling

    Theory and Applications
    • 1st Edition
    • Lawrence J. Berliner
    • English
    Spin Labeling II: Theory and Applications covers spin-labeled biopolymers and its importance to both macromolecular modeling as well as some industrially based problems. The book discusses the methods of saturation-transfer spectroscopy; the spin-probe-spin-labe... method; and new aspects of nitroxide chemistry. The text also describes the spin-labeled synthetic polymers; the impact that the technique of spin labeling has on pharmacology and on biomedicine; as well as the applications of spin labeling to nucleic acids. Chemists, pharmacologists, biochemists, and people working in the field of biological magnetic resonance will find the book invaluable.
  • Advances in Liquid Crystals

    Volume 6
    • 1st Edition
    • Glenn H. Brown
    • English
    Advances in Liquid Crystals, Volume 6 is a collection of scientific essays that focuses on the developments and applications in the field of liquid crystal science. The text begins with an article about the smectic phases of substances with rodlike molecules in layered structures. This article focuses on the nematic phases of polymorphism that include cubic thermotropic phases and blue phases. A section of the book provides an extensive discussion of the means of experimental procedures used to evaluate the spectra and the implications of the spectral parameters. A critical analysis of the influence of molecular vibration including interdependence on the average order parameters is also included. The terms nuclear relaxation, quadrupole coupling constants, chemical shielding anisotropy, molecular order, and molecular structure and conformation are explained in detail. The last article briefly discusses the actions of liquid crystal systems in the muscle and connective tissue. The book will provide valuable insights for scientists, developers of crystal displays, students, and researchers in the field of chemistry.
  • Biochemical Lesions and Lethal Synthesis

    International Series of Monographs on Pure and Applied Biology: Modern Trends in Physiological Sciences
    • 1st Edition
    • Rudolph A. Peters
    • English
    International Series of Monographs on Pure and Applied Biology, Volume 18: Biochemical Lesions and Lethal Synthesis focuses on biochemical lesions. The book first discusses biochemical lesions in thiamine deficiency and arsenical substances and biochemical lesions. The text also examines biochemical lesions in mustard gas poisoning. Concerns include sulfone, sulfoxide, vesication, and cross-linking. The book also describes inhibitors of enzymes containing thiol groups and toxicity. Cell division, thiol agents, epidemic dropsy, and sanguinarine are highlighted. The text further focuses on lethal synthesis and carbon-flourine compounds. The synthesis of fluorocitric acid, effects of fluorocitrate, carbon-fluorine compounds, and biochemical lesions induced by fluorocitrate are discussed. The text further describes biochemical lesions in burns and historical points and other biochemical lesions. Muscular contraction, antimetabolites, inborn errors, and study of the biochemistry of burn sites are explained. The text is highly recommended for readers wanting to study biochemical lesions.