Books in Medicinal chemistry

Prodrug Design

1st Edition
July 7, 2015
Vivekkumar K Redasani + 1 more
English
Paperback
9 7 8 0 1 2 8 0 3 5 1 9 1
eBook
9 7 8 0 1 2 8 0 3 5 5 7 3

Prodrug Design: Perspectives, Approaches and Applications in Medicinal Chemistry provides a focused overview of this critical area of drug discovery, as that continuous process strives not only to discover new drug compounds but also to modify the existing ones. This valuable primer supports this mission of drug development and its goal of reducing undesired effects and improving therapeutic effectiveness of drug compounds. Providing a unique compilation of data, insightful case studies, and review of existing literature in the area, the book will promote innovation in medicinal and pharmaceutical chemistry research, exploring the limitations of existing drugs and their improvement. Prodrug Design reviews marketed compounds, the safety of promoieties, and a detailed classification of prodrugs organized by therapeutic area for easy reference.

The Practice of Medicinal Chemistry

4th Edition
July 1, 2015
Camille Georges Wermuth + 3 more
English
Hardback
9 7 8 0 1 2 4 1 7 2 0 5 0
eBook
9 7 8 0 1 2 4 1 7 2 1 3 5

The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery.With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development.

Recent Advances in Medicinal Chemistry, Volume 1

1st Edition
June 2, 2015
Atta-ur Rahman + 2 more
English
Paperback
9 7 8 0 1 2 8 0 3 9 6 1 8
eBook
9 7 8 0 1 2 8 0 3 9 6 2 5

Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer antibiotics and non-steroidal anti-inflammatory drugs; aromatase inhibitors in adjuvant endocrine treatment of early-stage breast cancer in postmenopausal women; Rho GTPases and statins in targeting and developing therapies for tumors; and more.

Medicinal Chemistry of Anticancer Drugs

2nd Edition
April 28, 2015
Carmen Avendaño + 1 more
English
Paperback
9 7 8 0 4 4 4 6 2 6 4 9 3
eBook
9 7 8 0 4 4 4 6 2 6 6 7 7

Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design.

Progress in Medicinal Chemistry

1st Edition
Volume 54
January 30, 2015
G. Lawton + 1 more
English
Hardback
9 7 8 0 4 4 4 6 3 4 8 0 1
eBook
9 7 8 0 4 4 4 6 3 4 8 5 6

Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume includes chapters covering recent advances in cancer therapeutics, fluorine in medicinal chemistry, a perspective on the next generation of antibacterial agents derived by manipulation of natural products, a new era for Chagas Disease drug discovery? and imaging in drug development.

Annual Reports in Medicinal Chemistry

1st Edition
Volume 49
September 24, 2014
Manoj C Desai
English
Paperback
9 7 8 0 1 2 8 0 0 1 6 7 7
eBook
9 7 8 0 1 2 8 0 0 3 7 2 5

Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry with an emphasis on emerging topics in the biological sciences that are expected to provide the basis for entirely new future therapies.

Progress in Medicinal Chemistry

1st Edition
Volume 53
January 31, 2014
G. Lawton + 1 more
English
eBook
9 7 8 0 4 4 4 6 3 3 9 5 8

Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume continues in the serial's tradition of providing an insight into the skills required of the modern medicinal chemist; in particular, the use of an appropriate selection of the wide range of tools now available to solve key scientific problems, including g-secretase modulators, P2X7 antagonists as therapeutic agents for CNS disorders, N-type calcium channel modulators for the treatment of pain, and more.

Annual Reports in Medicinal Chemistry

1st Edition
Volume 48
September 13, 2013
Manoj C Desai
English
Paperback
9 7 8 0 1 2 4 1 7 1 5 0 3
eBook
9 7 8 0 1 2 4 1 7 1 5 1 0

Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.

Bioconjugate Techniques

3rd Edition
July 25, 2013
Greg T. Hermanson
English
Hardback
9 7 8 0 1 2 3 8 2 2 3 9 0
eBook
9 7 8 0 1 2 3 8 2 2 4 0 6

Bioconjugate Techniques, Third Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers.

Introduction to Biological and Small Molecule Drug Research and Development

1st Edition
May 7, 2013
C. Robin Ganellin + 2 more
English
Hardback
9 7 8 0 1 2 3 9 7 1 7 6 0

Introduction to Biological and Small Molecule Drug Research and Development provides, for the first time, an introduction to the science behind successful pharmaceutical research and development programs. The book explains basic principles, then compares and contrasts approaches to both biopharmaceuticals (proteins) and small molecule drugs, presenting an overview of the business and management issues of these approaches. The latter part of the book provides carefully selected real-life case studies illustrating how the theory presented in the first part of the book is actually put into practice. Studies include Herceptin/T-DM1, erythropoietin (Epogen/Eprex/NeoRec... anti-HIV protease inhibitor Darunavir, and more. Introduction to Biological and Small Molecule Drug Research and Development is intended for late-stage undergraduates or postgraduates studying chemistry (at the biology interface), biochemistry, medicine, pharmacy, medicine, or allied subjects. The book is also useful in a wide variety of science degree courses, in post-graduate taught material (Masters and PhD), and as basic background reading for scientists in the pharmaceutical industry.

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Books in Medicinal chemistry

Prodrug Design

The Practice of Medicinal Chemistry

Recent Advances in Medicinal Chemistry, Volume 1

Medicinal Chemistry of Anticancer Drugs

Progress in Medicinal Chemistry

Annual Reports in Medicinal Chemistry

Progress in Medicinal Chemistry

Annual Reports in Medicinal Chemistry

Bioconjugate Techniques

Introduction to Biological and Small Molecule Drug Research and Development