Pharmaceutical Engineering: A Primer for Advanced Process Development provides a comprehensive, engineering-focused description of pharmaceutical dosage form process development and manufacturing. This volume introduces the most commonly used manufacturing processes for pharmaceutical dosage forms and addresses critical formulation and process parameters that influence drug product process performance and product quality.This is supplemented with detailed descriptions of engineering models as well as tools that can be used to support their development and verification (such as process analytical technology (PAT)) as well as the appropriate utilization of process and equipment knowledge. Typical scale-up challenges inspired by real industrial examples will be presented as well as a review of the latest correlations, theories and models that can form the basis for science-based scale-ups and transfers.
Industrial Water Conservation: Systematic Design Tools and Case Studies offers fundamental knowledge of various established process integration tools for water conservation, including water pinch analysis and mathematical programming techniques. The book provides a demonstration of water conservation tools on various industrial case studies, enabling readers to learn how these methods can be implemented in actual industrial settings. Part A provides various systematic methods on water recovery system design based on process integration techniques, whereas Part B provides various industrial case studies covering the success stories of the implementation of the methods covered in Part A.This is an indispensable resource for practitioners in various industrial sectors – chemicals and petrochemicals, pulp and paper, food and beverage, textile, etc., consultants in water-related industries, as well as (post)-graduate students in chemical engineering.
Artificial Intelligence in Chemical Engineering explores the integration of artificial intelligence (AI) into various facets of chemical engineering. The book introduces historical information, highlights current state and trends in AI applications, and discusses challenges and opportunities within the field. Foundational principles of AI and machine learning are thoroughly covered, giving readers a solid understanding of basic AI principles, machine learning algorithms, and the crucial processes of model training and validation. The book then delves into the critical phase of data acquisition and preprocessing for AI models, addressing strategies for data collection, ensuring data quality, and techniques for feature engineering and selection.Subsequent chapters cover a wide spectrum of AI applications in chemical engineering. From supervised and unsupervised learning for process modeling to the advanced realm of deep learning applications, this book explores neural networks, convolutional and recurrent architectures, and their real-world applications in process optimization and analysis.
Machine Learning Tools for Chemical Engineering: Methodologies and Applications explores the integration of Machine Learning (ML) techniques within the chemical engineering domain. This book highlights the precision, speed, and flexibility of ML solutions in addressing complex challenges that traditional methods struggle with. It offers both practical tools and a theoretical framework, combining knowledge modeling, representation, and management tailored to the unique needs of chemical engineering. Beyond the introduction of ML, the book delves into philosophies such as knowledge modeling, knowledge representation, search and inference, and knowledge extraction and management.It is an invaluable resource for graduate students, researchers, educators, and industry professionals aiming to optimize and innovate in chemical processes through ML applications.
Higee Chemical Reaction Engineering systematically discusses the fundamentals, principles, and methods of molecular mixing and reaction process intensification. The book demonstrates the implementation approach, process, and effectiveness of Higee chemical reaction engineering through novel industrial case studies that help industrial technicians select reaction intensification technology route more scientifically. Sections cover the innovation and development process of Higee chemical reaction engineering, hydrodynamics behavior in Higee reactors, equipment design principles and methods, multiphase reaction of liquid-liquid, gas-liquid, gas-solid, gas-liquid-solid and reactive crystallization process intensification principles and effectiveness.Higee Chemical Reaction Engineering is a systematic summary of several national award and key projects, such as the State Technological Innovation Award, State Science and Technology Advancement Award, National Natural Science Foundation of China, National key R&D Program of China, National ‘‘863’’ Program of China, National ‘‘973’’ Program of China, and also some international cooperation.
Plant Hazard Analysis and Safety Instrumentation Systems serves as a comprehensive guide to the development of safety instrumented system (SIS), outlining the connections between SIS requirements, process hazard analysis, SIS lifecycle, implementation, safety analysis, and realization in control systems. The book also explores the impact of recent advances, such as SIL, SIS, and Fault Tolerance. In line with technological developments, it covers safety in wireless systems as well as in Industrie 4.0 and Digital Transformation.Plant Hazard Analysis and Safety Instrumentation Systems incorporates practical examples throughout the book. It covers safety analysis and realization in control systems, providing up-to-date descriptions of modern concepts like SIL, SIS, and SIF. The inclusion of security issues alongside safety issues is particularly relevant for the programmable systems used in modern plant instrumentation systems. The new chapters in this updated edition address security concerns crucial for programmable systems in modern plants- including topics such as discussion of hazardous atmospheres and their impact on electrical enclosures, the use of IS circuits, and their links to safety considerations in major developmental areas, including IIoT, Cloud computing, wireless safety, Industry 4.0, and digital transformation.This book is a valuable resource for Process Control Engineers, Process Engineers, Instrumentation Engineers, Safety Engineers, and Mechanical/Manufacturing Engineers from various disciplines, helping them understand how instrumentation and controls provide layers of protection for basic process control systems, ultimately increasing overall system reliability. Plant Hazard Analysis and Safety Instrumentation Systems will also be a great guide for researchers, students, and graduate level professionals in process safety disciplines, Electrical and Industrial Engineers specializing in safety and area classifications, as well as plant managers and engineers in the industry.
Advances and Technology Development in Greenhouse Gases: Emission, Capture and Conversion is a comprehensive series that discusses the composition and properties of greenhouse gases (GHGs) and introduces different sources of GHGs’ emission and the relation between GHGs and global warming. The comprehensive and detailed presentation of common technologies as well as novel research related to all aspects of GHGs makes this work an indispensable encyclopedic resource for researchers in academia and industry. Greenhouse Gases Storage and Transportation investigates in detail the methods of storage and transportation, their current status, novel strategies, and the conventional challenges. The book consists of four sections, the first three of which include various strategies employed in the storage and transportation of the major GHGs, namely, carbon dioxide, methane, and nitrous oxide. Each section addresses recent advances, new concepts, and the economic assessment of storage and transportation facilities. The last section surveys the challenges that storage and transportation of GHGs may face and delves into the major problems of the pipelines that are employed for the transportation of the materials.
Ludwig’s Applied Process Design for Chemical and Petrochemical Plants Incorporating Process Safety Incidents is ever evolving starting with the first edition some 60 years ago. The volumes in this fifth edition provide improved techniques and fundamental design methodologies to guide the practicing engineer in designing process equipment and applying chemical processes to the properly detailed hardware. As indicative of the new title, process safety incidents are incorporated in many of the chapters, reviewing the root causes, and how these could be mitigated in future. Like its predecessor, this new edition continues to present updated information for achieving optimum operational and process conditions and to avoid problems caused by inadequate sizing and lack of internally detailed hardware. The volumes provide both fundamental theories where applicable and direct application of these theories to applied equations essential in the design effort. This approach in presenting design information is essential for troubleshooting process equipment and in executing system performance analysis. Volume 1B continues to cover mixing of liquids, process safety and pressure[1]relieving devices, metallurgy and corrosion, and process optimization. It builds upon Ernest E. Ludwig’s classic text to further enhance its use as a chemical engineering process design manual of methods and proven fundamentals. This new edition includes new content on three-phase separation, mixing of liquids, ejectors, and mechanical vacuum systems, process safety and pressure-relieving devices, metallurgy and corrosion, and optimization of chemical process/blending. Some chapters review pressure-relieving devices and provide case studies for process safety incidents, which are well illustrated from US Chemical Safety Hazard Investigation Board (www.csb.gov). Finally, this book contains a glossary of Petroleum and Petrochemical Terminologies and Physical and Chemical Characteristics of Major Hydrocarbons.
Ludwig’s Applied Process Design for Chemical and Petrochemical Plants Incorporating Process Safety Incidents is ever evolving starting with the first edition some 60 years ago. The volumes in this fifth edition provide improved techniques and fundamental design methodologies to guide the practicing engineer in designing process equipment and applying chemical processes to the properly detailed hardware. As indicative of the new title, process safety incidents are incorporated in many of the chapters, reviewing the root causes, and how these could be mitigated in future. Like its predecessor, this new edition continues to present updated information for achieving optimum operational and process conditions and to avoid problems caused by inadequate sizing and lack of internally detailed hardware. The volumes provide both fundamental theories where applicable and direct application of these theories to applied equations essential in the design effort. This approach in presenting design information is essential for troubleshooting process equipment and in executing system performance analysis. Volume 1A covers (chapters 1 - 6), process planning, flow-sheeting and scheduling, cost estimation and economic, physical properties of liquids and gases, fluid flow, mechanical separations. It builds upon Ernest E. Ludwig’s classic text to further enhance its use as a chemical engineering process design manual of methods and proven fundamentals. This new edition contains twelve chapters, which include new content on three-phase separation, mixing of liquids, ejectors, and mechanical vacuum systems, process safety and pressure relieving devices, metallurgy and corrosion, and optimization of chemical process/blending. The chapters in Volume 1A review pressure-relieving devices and provide case studies for process safety incidents, which are well illustrated from US Chemical Safety Hazard Investigation Board (www.csb.gov). Finally, this book contains an extensive glossary of Petroleum and Petrochemical Terminologies and Physical and Chemical Characteristics of Major Hydrocarbons
A Roadmap for the Comprehensive Assessment of Natech Risk: Management and Control of Technological Accidents Triggered by Natural Hazards in the Framework of Climate Change covers the latest advancements concerning the quantitative risk assessment and the management of cascading events involving technological accidents caused by natural hazards. The topic is meticulously covered, providing a description of past accidents, case-studies, and quantitative figures that allow for the identification of the most vulnerable plant elements, of the complex features of accident scenarios, and of their rising trend that is possibly related to factors as climate change and growing industrialization.Methodologies aiming at the assessment of the actual performance of safety barriers and safety systems during or immediately after the impact of a natural event are also presented. Recent tools and data supporting the quantitative assessment of these features in the overall assessment of Natech risk are reported, highlighting the similarities with other typologies of cascading accidents. Several case studies are presented in the book, and each methodology presented is provided with an illustrative case-study providing guidance to its application.