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Elsevier

Books in Life sciences

  • Genome Chaos

    Rethinking Genetics, Evolution, and Molecular Medicine
    • 1st Edition
    • Henry H. Heng
    • English
    Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine transports readers from Mendelian Genetics to 4D-genomics, building a case for genes and genomes as distinct biological entities, and positing that the genome, rather than individual genes, defines system inheritance and represents a clear unit of selection for macro-evolution. In authoring this thought-provoking text, Dr. Heng invigorates fresh discussions in genome theory and helps readers reevaluate their current understanding of human genetics, evolution, and new pathways for advancing molecular and precision medicine.

  • Human Brainstem

    Cytoarchitecture, Chemoarchitecture, Myeloarchitecture
    • 1st Edition
    • George Paxinos + 2 more
    • English
    Human Brainstem: Cytoarchitecture, Chemoarchitecture, Myeloarchitecture explores how the human brainstem has been impeded by the unavailability of an up-to-date, comprehensive, diagrammatic and photographic atlas. Now, with the first detailed atlas on the human brainstem in more than twenty years, this book presents an accurate, comprehensive and convenient reference for students, researchers and pathologists.

  • Epigenetics and Regeneration

    • 1st Edition
    • Volume 11
    • English
    Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing the regenerative potential of damaged tissues by epigenetic drugs, as well as innovative, discipline spanning strategies to enhance cell reprogramming. As an all-inclusive, evidence-based volume, Epigenetics and Regeneration will stimulate discussion and boost new research in this fascinating and impactful area of translational epigenetics.

  • Wildlife Conservation in Africa

    A Scientific Approach
    • 1st Edition
    • S.S. Ajayi
    • English
    Wildlife Conservation in Africa: A Scientific Approach presents comprehensive management strategies for the consumptive and non-consumptive utilization of wildlife across Sub-Saharan Africa. It describes African economies that are currently dependent on wildlife resources and prescribes strategies for conserving biodiversity in both forests and animals in ecosystems across the continent. The book covers the history and current status of how Africa’s culture, traditions, healthcare and food sources are woven intricately around the local wildlife and resources. It is a necessary resource for researchers and practitioners in wildlife and ecological conservation, but is also useful for administrators and managers of protected areas.

  • Pregnancy and the Pharmaceutical Industry

    The Movement towards Evidence-Based Pharmacotherapy for Pregnant Women
    • 1st Edition
    • Kristine E. Shields
    • English
    Pregnancy and the Pharmaceutical Industry: The Movement towards Evidence-Based Care for Pregnant Women explores the issues surrounding the decision to undertake clinical trials with pregnant women. There is currently a lack of data on the safety and effectiveness of medications used during pregnancy as it is impossible to extrapolate that information from drug studies on men and non-pregnant women. As a majority of pregnant women confront a medical condition during their pregnancy, from simple pain, to ongoing or new medical issues, this book quantifies the current absence of pregnant women in drug studies and identifies ethical issues, barriers, litigation fears and opportunities. Those in the pharmaceutical industry, IRB members who approve or deny drug study plans, doctors, nurses and midwives working in obstetrics or involved in conducting studies at their institutions will find this book an essential resource.

  • Chromatin Signaling and Neurological Disorders

    • 1st Edition
    • Volume 12
    • English
    Chromatin Signaling and Neurological Disorders, Volume Seven, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship between chromatin signaling and neurological disorders, but they'll also discover approaches to better interpret and employ new diagnostic studies and epigenetic-based therapies. A diverse range of chapters from international experts speaks to the basis of chromatin and epigenetic signaling pathways and specific chromatin signaling factors that regulate a range of diseases. In addition to the basic science of chromatin signaling factors, each disease-specific chapter speaks to the translational or clinical significance of recent findings, along with important implications for the development of epigenetics-based therapeutics. Common themes of translational significance are also identified across disease types, as well as the future potential of chromatin signaling research.

  • Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part A

    • 1st Edition
    • Volume 621
    • English
    Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part A, Volume 621, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this volume covering Site-directed ethylation of membrane proteins for measuring conformational transitions in lipid bilayers, the Design and synthesis of fluorescent activity probes for protein phosphatases, Stains, Utilizing split-nanoLuc fragments as luminescent probes for protein solubility in living cells, SH2-domain based sensor for intracellular recognition of sulfo-tyrosine, DNA-encoded immunoglobulins for detection of parasites, An engineered TEV protease – calmodulin fusion based sensor for neuronal calcium recording, and much more.

  • Trends in Personalized Nutrition

    • 1st Edition
    • Charis M. Galanakis
    • English
    Trends in Personalized Nutrition explores the topic of personalized nutrition from multiple angles, addressing everything from consumer acceptance, to policies and cognitive dissonance. Sections in the book cover epigenetics, nutrigenomics, predicting glycemic response, and metabolomics and the role of bacteria. In addition, the book explores diet, obesity and personalized nutrition for athletes, women, and infants and children, along with a section on the role of modern technology in the promotion of personalized nutrition. Nutritionists, food technologists, food chemists, new product developers, academics, and researchers and physicians working in the field of nutrition will find this to be a great reference.

  • Advances in Agronomy

    • 1st Edition
    • Volume 156
    • English
    Advances in Agronomy, Volume 156, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial.

  • New Developments in Nanosensors for Pharmaceutical Analysis

    • 1st Edition
    • Sibel A. Ozkan + 1 more
    • English
    New Developments for Nanosensors in Pharmaceutical Analysis presents an overview of developments in nanosensor usage in pharmaceutical analysis, thereby helping pharmaceutical companies attain reliable, precise, and accurate analysis of pharmaceuticals. This book presents very simple, precise, sensitive, selective, fast, and relatively inexpensive methods for pre-treatment, prior to analysis. These methods may be considered for further application in clinical studies and assays. The book includes the manufacturing of sensors for pharmaceutical analysis at nano- or smaller scales, and gives simple and relatable designs for the fabrication of sensors. Twelve chapters cover an introduction to the topic, immobilization techniques, mechanism effect of nanomaterials on structure, optical nanosensors for pharmaceutical detection, chemical nanosensors in pharmaceutical analysis, noble metal nanoparticles in electrochemical analysis of drugs, photo-electrochemica... nanosensors for drug analysis, molecularly imprinted polymer based nanosensors for pharmaceutical analysis, nanomaterials for drug delivery systems, nanomaterials enriched nucleic acid-based biosensors, nanosensors in biomarker detection, and nanomaterials-based enzyme biosensors for electrochemical applications.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 74
    • English
    Advances in Microbial Physiology, Volume 74, the latest release in this ongoing series, continues the long tradition of topical, important, cutting-edge reviews in microbiology. The book contains updates in the field, with comprehensive chapters covering The electrifying physiology of Geobacter bacteria 30 years on, Adaptive morphogenesis in bacteria, Bacterial energetics and respiratory metabolism, Bacteria respiration during infection, Regulation of Organohalide Respiration, Bioenergetics of Campylobacter jejuni, Formate Hydrogenlyases, Bioenergetical Aspects of the Bacterial and Archaeal Hydrogen Metabolism, and more.

  • International Review of Cell and Molecular Biology

    • 1st Edition
    • Volume 346
    • English
    International Review of Cell and Molecular Biology, Volume 346, reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. Sections in this new release include the karyosphere (karyosome) and its peculiar structure of the oocyte nucleus, organoids as models of disease, lipid droplets as organelles, the dark side of apoptosis, interconnections between autophagy and secretion, and the regulation and function of intracellular pressure in cell biology.

  • Nanotechnology

    • 1st Edition
    • Volume 46
    • English
    Nanotechnology, Volume 46, the latest release in the Methods in Microbiology series, contains review articles on the application of nanotechnology in various fields of microbiology, including environmental microbiology, food microbiology and medical microbiology. Chapters in this new release include discussions on the Biosynthesis of Nanomaterials Utilizing Biomacromolecules, Nanotechnology in Medical Biology – Application of Nanodiagnostics in Infectious Diseases, Applications of Nanotechnology in Food Microbiology, Biosynthesis of Nanomaterials Utilizing Microorganisms, Nanotechnology in Medical Biology – Interaction of Pathogens and Nanostructured Surfaces, Biocompatible Polymers: Synthesis Methods, Surface Functionalization and its Biomedical Applications, and The Bacterial Flagellum.

  • Wilson Disease

    Pathogenesis, Molecular Mechanisms, Diagnosis, Treatment and Monitoring
    • 1st Edition
    • Karl Heinz Weiss + 1 more
    • English
    Wilson Disease: Pathogenesis, Molecular Mechanisms, Diagnosis, Treatment and Monitoring translates both clinical and experimental findings into a comprehensive approach for anyone involved in research and patient care. While the clinical variability of Wilson Disease poses a challenge from a diagnostic approach, the book uses the translational impact of new research findings to relate to new treatment concepts. Comprehensive chapters include common knowledge, guideline consensus statements, and discussions of clinical evidence. This is a must-have reference for researchers and clinicians in translational research.

  • Advances in Phytonanotechnology

    From Synthesis to Application
    • 1st Edition
    • Mansour Ghorbanpour + 1 more
    • English
    Advances in Phytonanotechnology: From Synthesis to Application guides readers through various applications of nanomaterials on plants by presenting the latest research related to nanotechnology and nanomaterials on plant systems. The book focuses on the effects of these applications on plant morphology, physiology, biochemistry, ecology and genetics. Sections cover the impact on plant yield, techniques, a review of positive and negative impacts, and an overview of current policies regarding the use of nanotechnology on plants. Additionally, the book offers insights into the appropriate application of nanoscience to plants and crops for improved outcome and an exploration of their bioavailability and toxicity in the environment.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 90
    • English
    Advances in Clinical Chemistry, Volume 90, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Advances in Insect Physiology

    • 1st Edition
    • Volume 56
    • English
    Advances in Insect Physiology, Volume 56, provides readers with the latest interdisciplinary reviews on the topic. It is an essential reference source for invertebrate physiologists, neurobiologists, entomologists, zoologists, and insect chemists, with this new release focusing on the Effects of resource limitation on the strengths of tradeoffs in insect lifecycles, The circadian system in insects: cellular, molecular, and functional organization, Molecular Physiology of the Insect Midgut, The Cryptonephridic system in Lepidoptera, Subsocial insects and the physiology of parental care, Mechanisms regulating phenotypically plastic traits in wing polymorphic insects, and more.

  • Paxinos and Franklin's the Mouse Brain in Stereotaxic Coordinates, Compact

    The Coronal Plates and Diagrams
    • 5th Edition
    • Keith B.J. Franklin + 1 more
    • English
    Paxinos and Franklin's The Mouse Brain in Stereotaxic Coordinates, Compact Fifth Edition, is the compact version of the most widely used and cited atlas of the mouse brain in print. It emulates in design and accuracy Paxinos and Watson’s The Rat Brain in Stereotaxic Coordinates, the most cited publication in neuroscience. The compact edition provides the coronal plates and diagrams of the full mouse atlas in a smaller, more convenient spiral format and at a student friendly price. High resolution digital photographs of the coronal plane of section from the full 5th edition complement the coronal drawings. Unique to the compact, it includes an introduction to the use of the atlas in stereotaxic surgery.

  • Protein Modificomics

    From Modifications to Clinical Perspectives
    • 1st Edition
    • Tanveer Ali Dar + 1 more
    • English
    Protein Modificomics: From Modifications to Clinical Perspectives comprehensively deals with all of the most recent aspects of post-translational modification (PTM) of proteins, including discussions on diseases involving PTMs, such as Alzheimer’s, Huntington’s, X-linked spinal muscular atrophy-2, aneurysmal bone cyst, angelman syndrome and OFC10. The book also discusses the role PTMs play in plant physiology and the production of medicinally important primary and secondary metabolites. The understanding of PTMs in plants helps us enhance the production of these metabolites without greatly altering the genome, providing robust eukaryotic systems for the production and isolation of desired products without considerable downstream and isolation processes.

  • Sweet Potato

    Chemistry, Processing and Nutrition
    • 1st Edition
    • Taihua Mu + 1 more
    • English
    Sweet Potato: Chemistry, Processing, and Nutrition presents foundational information, including identification, analysis, and use of chemical components from sweet potato in a variety of food and nonfood uses. Sweet potatoes can be easily propagated, are rich source of carbohydrates and functional components, and are highly productive, which makes them most suitable for production of staple and functional foods. With the increasing population and the challenges of providing healthy food to the world, there is an increasing consumer demand for new and better sweet potato products, particularly for those in developing countries. Providing a brief description of the specific sweet potato components, their role during processing and strategies for quality optimization, this book also explores novel methods of sweet potato starch, protein, and pectin modification providing students, researchers, and technologists working in the area of food science and others with the most recent information and state-of-the-art technology for developing new and beneficial uses of sweet potato.

  • Mitochondrial Medicine

    A Primer for Health Care Providers and Translational Researchers
    • 1st Edition
    • Pankaj Prasun
    • English
    Mitochondrial Medicine: A Primer for Health Care Providers and Translational Researchers is an applied, holistic resource that addresses the evolving and multidisciplinary area of mitochondrial disease. The book discusses the fundamentals of mitochondrial medicine in humans, as well as the pathophysiology, diagnosis and treatment of mitochondrial diseases. Three all-inclusive sections examine the role of mitochondria in common medical conditions, such as diabetes, heart failure and the full range of inherited mitochondrial diseases. Sections cover the genetic and biochemical basis of both mitochondrial DNA deletion syndromes and point mutation syndromes, their clinical presentation, treatment plans, genetic counseling, prenatal testing, and ongoing research. While providing a solid foundation in its topic area, each chapter in the book is written in an accessible format with illustrative case studies, thus making it a quick bedside or clinical laboratory reference.

  • Transgenerational Epigenetics

    • 2nd Edition
    • Volume 13
    • English
    Transgenerational Epigenetics, Second Edition, offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with an emphasis on human disease relevance, drug discovery, and next steps in clinical translation. International experts discuss mechanisms of epigenetic inheritance, its expression in animal and plant models, and how human ailments, such as metabolic disorders and cardiovascular disease are influenced by transgenerational epigenetic inheritance. Where evidence is sufficient, epigenetic clinical interventions are proposed that may help prevent or reduce the severity of disease before offspring are born. This edition has been thoroughly revised in each disease area, featuring newly researched actors in epigenetic regulation, including long noncoding RNA in addition to histone modifications and DNA methylation. Therapeutic pathways in treating cancer and extending human longevity are also considered, as are current debates and future directions for research.

  • Neural Network Modeling and Identification of Dynamical Systems

    • 1st Edition
    • Yury Tiumentsev + 1 more
    • English
    Neural Network Modeling and Identification of Dynamical Systems presents a new approach on how to obtain the adaptive neural network models for complex systems that are typically found in real-world applications. The book introduces the theoretical knowledge available for the modeled system into the purely empirical black box model, thereby converting the model to the gray box category. This approach significantly reduces the dimension of the resulting model and the required size of the training set. This book offers solutions for identifying controlled dynamical systems, as well as identifying characteristics of such systems, in particular, the aerodynamic characteristics of aircraft.

  • Advances in Biological Science Research

    A Practical Approach
    • 1st Edition
    • Surya Nandan Meena + 1 more
    • English
    Advances in Biological Science Research: A Practical Approach provides discussions on diverse research topics and methods in the biological sciences in a single platform. This book provides the latest technologies, advanced methods, and untapped research areas involved in diverse fields of biological science research such as bioinformatics, proteomics, microbiology, medicinal chemistry, and marine science. Each chapter is written by renowned researchers in their respective fields of biosciences and includes future advancements in life science research.

  • EEG-Based Experiment Design for Major Depressive Disorder

    Machine Learning and Psychiatric Diagnosis
    • 1st Edition
    • Aamir Saeed Malik + 1 more
    • English
    EEG-Based Experiment Design for Major Depressive Disorder: Machine Learning and Psychiatric Diagnosis introduces EEG-based machine learning solutions for diagnosis and assessment of treatment efficacy for a variety of conditions. With a unique combination of background and practical perspectives for the use of automated EEG methods for mental illness, it details for readers how to design a successful experiment, providing experiment designs for both clinical and behavioral applications. This book details the EEG-based functional connectivity correlates for several conditions, including depression, anxiety, and epilepsy, along with pathophysiology of depression, underlying neural circuits and detailed options for diagnosis. It is a necessary read for those interested in developing EEG methods for addressing challenges for mental illness and researchers exploring automated methods for diagnosis and objective treatment assessment.

  • Noonan Syndrome

    Characteristics and Interventions
    • 1st Edition
    • Amrit P.S. Bhangoo
    • English
    Noonan Syndrome: Characteristics and Interventions provides an in-depth analysis on this disorder that pediatric endocrinologists and primary care clinicians can use to make sure they provide affected patients with an updated model of care and appropriate treatment. The book examines recent advances in understanding and treating short stature in Noonan Syndrome, along with the latest progress in growth hormone-dependent signaling pathways involved in short stature, one of the most frequent clinical manifestations. Chapters also address how patients with Noonan Syndrome undergo more than average surgical procedures and have a great bleeding risk. This must have reference for pediatric endocrinologists and practicing physicians will give them all the information they need on the topic.

  • Sports and Energy Drinks

    Volume 10: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Sports and Energy Drinks, Volume 10 in The Science of Beverages series, is the first single-volume resource to focus on the science behind these beverages-for-purpos... products. As consumers seek ways to effectively replenish key nutrients after strenuous activity—while also balancing calories and vitamin intake—sports and energy drinks is one of the fastest growing markets in the industry. From protein to fruit, athlete to adolescent consumption, this book explores the key issues and challenges in developing products that meet consumer demand in a safe-and-effective manner. This series takes a multidisciplinary approach to help research and development professionals understand the scientific complexities of these unique beverages. As demand for sports and energy drinks is growing and with a more competitive market, this timely and useful resource will equip industry professionals with the tools they need to create new and innovative health-promoting products.

  • Milk-Based Beverages

    Volume 9: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Milk-Based Beverages, Volume 9 in The Science of Beverages series, presents current status, developments, and technologies for researchers and developers to meet consumer demand and understand consumer trends toward healthy drinks. This resource takes a multidisciplinary approach to address issues in safety and quality control, while also discussing the nutritional and functional information that professionals in the beverage industry need. The book presents a framework for researchers, product developers, engineers, and regulators in the beverages industry for understanding new research developments in milk-based products to meet industry needs in producing competitive products.

  • Companion and Complementary Diagnostics

    From Biomarker Discovery to Clinical Implementation
    • 1st Edition
    • Jan Trøst Jørgensen
    • English
    Companion and Complementary Diagnostics: From Biomarker Discovery to Clinical Implementation provides readers with in-depth insights into the individual steps in the development of companion diagnostic assays, from the early biomarker discovery phase straight through to final regulatory approval. Further, the clinical implementation of companion diagnostic testing in the clinic is also discussed. As the development of predictive or selective biomarker assays linked to specific drugs is substantially increasing, this book offers comprehensive information on this quickly-evolving area of biomedicine. It is an essential resource for those in academic institutions, hospitals and pharma, and biotech and diagnostic commercial companies.

  • New Approaches for Flavin Catalysis

    • 1st Edition
    • Volume 620
    • English
    New Approaches for Flavin Catalysis, Volume 620, a new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this update include Anaerobiosis and Methods for Reduction, Reduction Potentials, Anaerobic Stopped-Flow, No Glove-Box, Anaerobic Stopped-Flow, in a Glove-Box, Chemical Quenching, Oxygen Reactions, Double-mixing Stopped-Flow, Kinetic Isotope Effects and Viscosity Effects, Heavy Enzymes Synthetic Flavins & Linear Free Energy Relationships, Vibrational Spectroscopy, Stark Spectroscopy, EPR and Related Methods, Molecular Dynamics, Phylogenetic Relationships/Superf... O2 and Superoxide Analogs, and more.

  • Sleep Deprivation and Cognition

    • 1st Edition
    • Volume 246
    • English
    Sleep Deprivation and Cognition, Volume 247, the latest release in the Progress in Brain Research series, covers the effects of sleep deprivation, with this new release featuring sections on the Impact of sleep deprivation on long-term memory, Adolescent sleep restriction effects on cognition and mood, Self- regulation and social behavior during sleep deprivation, Experiential decision-making and the effects of sleep loss, Sleep deprivation and dynamic attentional control, a Pharmacogenetic approach to understanding sleep deprivation and cognition, Neuroimaging of functional connectivity in the sleep-deprived brain: what does it tell us?, and more.

  • Telemedicine Technologies

    Big Data, Deep Learning, Robotics, Mobile and Remote Applications for Global Healthcare
    • 1st Edition
    • D. Jude Hemanth + 1 more
    • English
    Telemedicine Technologies: Big Data, Deep Learning, Robotics, Mobile and Remote Applications for Global Healthcare illustrates the innovative concepts, methodologies and frameworks that will increase the feasibility of the existing telemedicine system. The book also focuses on showcasing prototypes of remote healthcare systems, thus emphasizing the data processing side that is often recognized as the backbone of any telemedicine system.

  • Climate Change and Agricultural Ecosystems

    Current Challenges and Adaptation
    • 1st Edition
    • Krishna Kumar Choudhary + 1 more
    • English
    Climate Change and Agricultural Ecosystems explains the causative factors of climate change related to agriculture, soil and plants, and discusses the relevant resulting mitigation process. Agricultural ecosystems include factors from the surrounding areas where agriculture experiences direct or indirect interaction with the plants, animals, and microbes present. Changes in climatic conditions influence all the factors of agricultural ecosystems, which can potentially adversely affect their productivity. This book summarizes the different aspects of vulnerability, adaptation, and amelioration of climate change in respect to plants, crops, soil, and microbes for the sustainability of the agricultural sector and, ultimately, food security for the future. It also focuses on the utilization of information technology for the sustainability of the agricultural sector along with the capacity and adaptability of agricultural societies under climate change. Climate Change and Agricultural Ecosystems incorporates both theoretical and practical aspects, and serves as base line information for future research. This book is a valuable resource for those working in environmental sciences, soil sciences, agricultural microbiology, plant pathology, and agronomy.

  • 250 examens de laboratoire

    en pratique médicale courante
    • 13th Edition
    • René Caquet
    • French
    Les examens de laboratoire, parfois qualifiés d’examens «complémentaires» alors qu’ils sont indispensables, recherchent bactéries et virus, reconnaissent les cellules anormales, détectent les anticorps, évaluent le fonctionnement des organes, scrutent le milieu intérieur, examinent les gènes.Comment s’en passer ?Ce livre, élaboré par un clinicien, offre aux professionnels de santé un instrument de pratique quotidienne. Ouvrage de référence, il expose tout ce qu’il faut savoir pour prescrire des analyses médicales et interpréter les résultats.Les examens de laboratoire sont présentés sous forme de fiches, classées par ordre alphabétique, qui suivent un plan récurrent : mode et précautions de prélèvement, valeurs normales et cliniques (valeurs pathologiques), objectifs de l’examen et interprétation.Cet ouvrage décrit le raisonnement qui permet de déduire d’un résultat biologique les meilleures conclusions diagnostiques ou thérapeutiques possibles, en interprétant les résultats à la lumière de la clinique, de la littérature scientifique et des données de santé publique.Cette 13e édition est entièrement actualisée, notamment en fonction des publications récentes, des recommandations des sociétés savantes (VIH, allergies, auto-immunité...) et en accord avec la nomenclature de la Sécurité sociale.De nouveaux examens liés à l’actualité médicale (caryotype onco-hématologique, hématocrite, hépatite E…) sont ajoutés.L’ouvrage s’accorde volontairement à la pratique des généralistes, spécialistes et biologistes. Les examens plus rares (biologie moléculaire…) sont traités en accord avec la demande.

  • Inspiring Conversations with Women Professors

    The Many Routes to Career Success
    • 1st Edition
    • Anna Garry
    • English
    Inspiring Conversations with Women Professors: The Many Routes to Career Success provides stories behind the many paths to professorship taken by these featured women. It includes information on their diverse life stories and how they navigated the beginning, middle stages, and other parts of their careers, including unexpected paths, support and how they got hooked by science/their field. In addition, they discuss why they chose this career, the obstacles they encountered, and how they found a way forward. Each interview encapsulates the advice and practical solutions they give.

  • Human Embryos and Preimplantation Genetic Technologies

    Ethical, Social, and Public Policy Aspects
    • 1st Edition
    • E. Scott Sills + 1 more
    • English
    Human Embryos and Preimplantation Genetic Technologies: Ethical, Social, and Public Policy Aspects presents the first holistic analysis of PGD and PGS as it is practiced and regulated worldwide. In addition to scientific and technical aspects, the book provides perspectives on the ethical, legal, religious, policy and social implications of global assisted reproduction technologies, including in Africa, Asia, Europe, North and South America, and Australia. Chapters cover history, ethics, feminism, family dynamics, psychological and interpersonal factors, the current state of PGD and PGS in 20 different sovereign nations and religious communities, and provide an analysis of public policy concerns and future directions.

  • The Little Black Book of Neurology

    • 6th Edition
    • Osama O. Zaidat + 2 more
    • English
    Widely known and well-respected, The Little Black Book of Neurology has been a thorough yet portable reference in this complex field for more than 30 years, presenting definitions, classifications, and guidance on diagnosis and management for a wide range of neurological disorders. The 6th Edition offers updated and expanded coverage of neuropharmacology and neuroimaging – plus a new, more user-friendly, fast-access format that makes the book ideal for quick clinical consultation or as a refresher for the Boards.

  • Les troubles du sommeil

    • 3rd Edition
    • Yves Dauvilliers
    • French
    La médecine du sommeil est une discipline récente et les manuels qui lui sont consacrés sont peu nombreux. Les troubles du sommeil et de l’éveil touchent pourtant une part importante de la population et ont de graves répercussions sur la santé physique et mentale, ainsi que sur la qualité de vie.La 3e édition de cet ouvrage de référence, entièrement mis à jour et agrémenté de questionnaires, d’échelles et d’un glossaire étendu :• fait le point sur le sommeil normal (aspects neurobiologiques et physiologiques chez l’enfant, l’adulte et le sujet âgé),• présente les différentes méthodes d’exploration,• propose une synthèse sur les multiples troubles (insomnie, hypersomnie, troubles du rythme circadien, parasomnie…),• établie le lien entre les troubles du sommeil et les spécialités médicales : neurologie, cardiologie, pneumologie, endocrinologie, pédiatrie, psychiatrie, ORL….Cet ouvrage s’adresse aux médecins généralistes et spécialistes. Ils y trouveront des réponses à leurs questions, ainsi que de nombreuses indications pour la prise en charge des patients et la prescription de traitements. Il s’adresse également à tous les professionnels de santé, chercheurs et étudiants désireux de s’ouvrir à un domaine encore peu enseigné dans les facultés et écoles.

  • Progress in Molecular Biology and Translational Science

    Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part B
    • 1st Edition
    • Volume 163
    • English
    Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part B, Volume 163 in the Progress in Molecular Biology and Translational Science series, provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include an Overview of Fugal Glycan-based Therapeutics, Heparin: An Essential Drug for Modern Medicine, Low Molecular Weight Heparins and Their Clinical Applications, The Clinical Use of Fondaparinux: A Synthetic Heparin Pentasaccharid, Heparinoids as Clinically Used Drugs, Marine Glycan-Derived Therapeutics in China, Efficacy of Heparinoid PSS in Treating Cardiovascular and other Diseases—30 Years Clinical Applications in China, and more.

  • Advances in Parasitology

    • 1st Edition
    • Volume 104
    • David Rollinson + 1 more
    • English
    Advances in Parasitology, Volume 104, the latest in a series first published in 1963, contains comprehensive reviews on all areas of interest in contemporary parasitology. The series includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy, and life history, which help to shape current thinking and applications. This new release includes sections on Leishmania Tropica, Extracellular Vesicles in Host-Parasite Interaction, Cathepsins and Vaccines for Fascioliosis, Echinococcosis Transmission on the Tibetan Plateau, A Review of Diagnostics for STH from a Public Health Perspective, and Zoonotic Transmission of Intestinal Parasites: Implications for Control and Elimination.

  • Evolution's Clinical Guidebook

    Translating Ancient Genes into Precision Medicine
    • 1st Edition
    • Jules J. Berman
    • English
    Evolution's Clinical Guidebook: Translating Ancient Genes into Precision Medicine demonstrates, through well-documented examples, how an understanding of the phylogenetic ancestry of humans allows us to make sense out of the flood of genetic data streaming from modern laboratories and how it can lead us to new ways to prevent, diagnose and treat diseases. Topics cover evolution and human genome, meiosis and other recombinants events, embryology, speciation, phylogeny, rare and common diseases, and the evolution of aging. This book is a valuable source for bioinformaticians and those in the biomedical field who need knowledge, down to gene level, to fully comprehend currently available data.

  • The Comorbidities of Epilepsy

    • 1st Edition
    • Marco Mula
    • English
    Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers.

  • Advances in Agronomy

    • 1st Edition
    • Volume 155
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 155, the newest release in this valuable serial, continues to be recognized as a leading reference and first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied and exemplary of the abundant subject matter addressed by this long-running serial.

  • Context

    The Effects of Environment on Product Design and Evaluation
    • 1st Edition
    • Herbert L. Meiselman
    • English
    Context: The Effects of Environment on Product Design and Evaluation addresses the environment, or context, in which we consume products and the impact of context on choice and acceptability. The book explores what context is, how it influences design by specialists, and acceptance by consumers. Chapters discuss the basics of context, food and drink in context, testing a range of other products, and other contextual variables. Historically, research on context has been done in the laboratory and various natural locations, but rapid growth in other methods to study context, including evoked contexts, immersive contexts, virtual reality contexts, and more have widened research possibilities. Appealing to the professional, academic and commercial markets, this book will be of interest to those who conduct research in product development and product testing, to those who study what controls product usage, including eating from the health perspective, and to those who make decisions about product and space development.

  • Cadmium Tolerance in Plants

    Agronomic, Molecular, Signaling, and Omic Approaches
    • 1st Edition
    • Mirza Hasanuzzaman + 1 more
    • English
    Cadmium Toxicity and Tolerance in Plants: Agronomic, Genetic, Molecular and Omic Approaches presents research and latest developments on mechanisms of cadmium tolerance covering both lab and field conditions. This book contains important insights and options for minimizing Cd accumulation in plants and mitigating Cd toxicity. Topics covered include using various omics approaches to understanding plant responses to Cd, novel technologies for developing Cd tolerance and integrated breeding approaches to mitigate Cd stress in crops. Cadmium Toxicity and Tolerance in Plants: Agronomic, Genetic, Molecular and Omic Approaches is a valuable resource for both researchers and students working on cadmium pollution and plant responses as well as related fields of environmental contamination and toxicology.

  • Animal Models in Cancer Drug Discovery

    • 1st Edition
    • Asfar Azmi + 1 more
    • English
    Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on how these newer models could de-risk modern drug discovery. Areas covered include up to date information on latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer immunotherapy and how they leverage personalized therapies. The chapter on larger animal, canine models and their use in and their use in pre-investigational new drug (pre-IND) development makes the volume unique. Unlike before, the incorporation of several simplified protocols, breeding methodologies, handling and assessment procedures to study drug intervention makes this book a must read. Animal Models in Cancer Drug Discovery is a valuable resource for basic and translational cancer researchers, drug discovery researchers, contract research organizations, and knowledge seekers at all levels in the biomedical field.

  • Sleep and Health

    • 1st Edition
    • Michael A. Grandner
    • English
    Sleep and Health provides an accessible yet comprehensive overview of the relationship between sleep and health at the individual, community and population levels, as well as a discussion of the implications for public health, public policy and interventions. Based on a firm foundation in many areas of sleep health research, this text further provides introductions to each sub-area of the field and a summary of the current research for each area. This book serves as a resource for those interested in learning about the growing field of sleep health research, including sections on social determinants, cardiovascular disease, cognitive functioning, health behavior theory, smoking, and more.

  • Evaluation Technologies for Food Quality

    • 1st Edition
    • Jian Zhong + 1 more
    • English
    Evaluation Technologies for Food Quality summarizes food quality evaluation technologies, which include sensory evaluation techniques and chemical and physical analysis. In particular, the book introduces many novel micro and nano evaluation techniques, such as atomic force microscopy, scanning electron microscopy, and other nanomaterial-based methods. All topics cover basic principles, procedures, advantages, limitations, recent technology development, and application progress in different types of foods. This book is a valuable resource for scientists in the field of food science, engineering, and professionals in the food industry, as well as for undergraduate and postgraduate students studying food quality evaluation technology.

  • Sex Determination in Vertebrates

    • 1st Edition
    • Volume 134
    • English
    Sex Determination, Volume 134, the latest release in the Current Topics in Developmental Biology series, contains current reviews in the field of vertebrate sex determination. It covers molecular pathways of sex determination in genetic and environmental species and encompasses both sex determination of somatic lineages and commitment of germ cells to male or female fate. Chapters in this new release cover, amongst other topics, Mapping the Sox9 Enhancer Elements, Epigenetic Regulation of Sex Determination, Evolution and Management of Sex Chromosomes, Regulation of Germ Cell Sex Identity in Medaka, Control of Sex Determination in Zebrafish, Sexually Dimorphic Germ Cell Identity in Mammals, and more.

  • Molecular Mechanisms of Dementia

    Biomarkers, Neurochemistry, and Therapy
    • 1st Edition
    • Akhlaq A. Farooqui
    • English
    Considerable progress has been made in neurochemical and therapeutic aspects of dementia research in recent years. Molecular and Therapeutic Aspects of Dementia presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of dementias. It provides a clearly written and logically organized and comprehensive overview of molecular aspects of risk factors, symptoms, pathogenesis, biomarkers, and therapeutic strategies for various types of dementia. This book is written for the international audience of neurochemists, neuroscientists, neurologists, neuropharmacologists... and clinicians. The hope is that this discussion will not only integrate and consolidate knowledge in this field, but will jumpstart more studies on molecular mechanisms and therapeutic aspects of dementia. The comprehensive information in this monograph may not only help in early detection of various types of dementia and dementia linked neurological disorders, but also promote discovery of new drugs, which may block or delay the onset of dementia in elderly patients. Understanding the course of dementia is important not only for patients, caregivers, and health professionals, but also for health policy-makers, who have to plan for national resources needed in the management of an increasing number of dementia cases.　

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