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Books in Life sciences

  • Contemporary Issues in Experimental Phonetics

    • 1st Edition
    • Norman Lass
    • English
    Contemporary Issues in Experimental Phonetics provides comprehensive coverage of a number of research topics on experimental phonetics. This book is divided into four parts. Part I describes the instrumentation systems employed in the study of speech acoustics and speech physiology. The models, aerodynamic principles, and peripheral physiological mechanisms of speech production are discussed in Part II. Part III explains the problems in the specifications of the acoustic characteristics of speech sounds and suprasegmental features of speech. The speech perception process, speaker recognition, theories on the nature of the dichotic right ear advantage, and errors in auditory perception are elaborated in the last chapter. This text likewise covers the measurement of temporal processing in speech perception and interrelationship of speech, hearing, and language in an understanding of the total human communication process. This publication is valuable to speech and hearing scientists, speech pathologists, audiologists, psychologists, linguists, and graduate students researching on experimental phonetics.

  • Molecular Basis of Lysosomal Storage Disorders

    • 1st Edition
    • John Barranger
    • English
    Molecular Basis of Lysosomal Storage Disorders contains the proceedings of the 1983 Conference on the Molecular Basis of Lysosomal Storage Disorders, held at the National Institutes of Health in Bethesda, Maryland. The papers focus on the molecular biology of, and therapeutic approaches to, lysosomal storage disorders, such as mucopolysaccharidose... sphingolipidoses, and Gaucher disease. Organized into six sections comprised of 29 chapters, this book begins with an overview of enzymes, activator proteins, and stabilizers that underlie lysosomal storage disorders. It then discusses some developments in enzyme purification, receptors for glycoprotein enzymes, factors that control endocytosis, and the intracellular fate of lysosomal hydrolases. Some chapters explain the enzyme biosynthesis, bone marrow transplantation, and enzyme replacement, along with cell hybridization, chromosome localization, phenotype discrimination, and cloning of genes for human lysosomal enzymes. This book is helpful to biochemists, physiologists, pathologists, geneticists, clinical investigators, and practicing physicians concerned with the study, care, and treatment of patients with hereditary metabolic disorders, as well as undergraduate and graduate level students involved in research in this discipline.

  • Lipoprotein Kinetics and Modeling

    • 1st Edition
    • Mones Berman
    • English
    Lipoprotein Kinetics and Modeling contains some of the papers presented at a conference on the analysis and modeling of lipoprotein kinetic data held in Phoenix, Arizona. Contributions from both theorists and experimentalists who attended the conference focus on the developments in the use of mathematical modeling in analyzing the lipoprotein kinetics. The conference highlights the role of kinetic modeling in elucidating the dynamic processes involved in lipoprotein metabolism, the result of improper data analysis that can lead to erroneous physiological interpretations, and the emerging complexities in the lipoprotein system. Organized into six sections comprised of 37 chapters, this book begins with an overview of the theory and applications of kinetic analysis and modeling to lipoproteins. It then discusses the role of kinetic modeling in physiology, the kinetics of apoprotein B in humans, the use of kinetics in investigating the metabolism of very low and intermediate-density lipoproteins, and the models of plasma lipoprotein triglyceride kinetics. It explains the cholesterol kinetics and modeling, the kinetics of high density lipoprotein metabolism in humans, and various techniques for the analysis and modeling of lipoprotein kinetic data such as KABIS (kinetic analysis by interactive simulation) and CONSAM (conversational version of the SAAM modeling program). This book will be of interest to biologists, physiologists, clinical researchers and experts in computer technology and mathematics.

  • Handbook of B and T Lymphocytes

    • 1st Edition
    • English
    To compile this up-to-date handbook, Dr. Charles Snow of the University of Kentucky Medical Center has assembled works by a premier group of active investigators who meet the needs of todays researchers. The handbookprovides a broad overview of the historical and current research in B- and T-cell biology, and presents the latest developments in this fast-breaking field to all professionals concerned with the humoral immune response of the body.

  • Parasitic Protozoa

    Babesia and Plasmodia
    • 2nd Edition
    • English
    Updated and much expanded, the Second Edition of Parasitic Protozoa is designed to be useful to physicians, veterinarians, and research scientists concerned with diseases caused by protozoa in man, and in domestic and wild animals including fish, mollusks and insects, as well as the more commonly considered vertebrate animals. Each section contains information on disease pathogens, treatment, diagnosis, and epidemiology of the diseases caused by the various protozoans. The book is not limited to these medically-oriented subjects, but treats taxonomy, morphology, and metabolism of the organisms in such a way as to be of interest to scientists and graduate students working in the field of protozoology. The entire edition, published in ten volumes, is arranged so that subjects of common interest occupy individual volumes.

  • Toxins in Plant Disease

    • 1st Edition
    • R Durbin
    • English
    Toxins in Plant Disease presents a comprehensive coverage of plant disease toxins, both those for which there are reasonable evidence and those with fewer credentials. This book is primarily concerned with the mechanism wherein substances that interfere with metabolism or that alter the normal structure of protoplasm are produced and released (category 1); this includes the traditional toxins, which are usually of low molecular weight. It also describes category 2 mechanism, wherein substances that interfere with normal control of growth and development are produced and released; these microorganisms are classified as growth-affecting compounds. Moreover, this text addresses some high-molecular-weigh... compounds that contribute to vascular dysfunction. It further talks about the production, isolation, assay, genetics of production, mechanism of action, structure-activity relationship, metabolism, and applications of these toxins. This publication will provide a rational basis for future investigations and contribute to the eventual understanding of the role that toxins play in disease causation.

  • Glutathione Centennial

    Molecular Perspectives and Clinical Implications
    • 1st Edition
    • Naoyuki Taniguchi
    • English
    Glutathione Centennial: Molecular Perspectives and Clinical Implications is a collection of papers presented at the international symposium by the same titles, held in Osaka, Japan on December 1-4, 1988. This symposium concentrates on the developments is glutathione field, especially those related to molecular and clinical problems. This book is organized into five parts encompassing 30 chapters. Part I deals with the metabolic regulation, thermodynamic and kinetic properties, and enzyme regulation of glutathione. Part II examines the gene expression and molecular mechanism of glutathione-related enzymes, while Part III explores the association between carcinogenesis, xenobiotic compounds, and glutathione. Part IV highlights the clinical implications of glutathione, particularly its effect on vasospasm in subarachnoid hemorrhage and experimental hepatitis. Part V discusses the mechanism and regulation of biological transport of glutathione. This book will be of great value to glutathione enthusiasts and to many scientists in the brad fields of biology and medicine, and to their students.

  • Cytokines and B Lymphocytes

    • 1st Edition
    • Robin E. Callard
    • English
    Over the past five years the major importance of cytokines in the regulation of the immune system has become established. This book is the first to review the role of these factors in the control of growth of differentiation of B lymphocytes and thus represents an up-to-date and timely overview of the B-cell response.For the immunologist, there are detailed accounts of the physio-chemical properties of the relevant cytokines and their effect on B lymphocytes from the level of receptor signalling, through ontogeny, activation and proliferation to the expression of specific immunoglobulin isotypes. For the clinician, the involvement of cytokines in disease and normal immune response is discussed.

  • Nutrition of Grazing Ruminants in Warm Climates

    • 1st Edition
    • English
    @from:From the PrefaceThe objective of this book is to review the basic knowledge and methodology of feeding grazing ruminants in tropical and semitropical countries. It is hoped this information will be of use to farmers, research specialists, teachers, students, extension specialists, feed manufacturers, and others throughout the world concerned with the nutrition of grazing ruminants. A unique feature is the identification of nutritional limitations of grazing ruminants in the tropics, which will be beneficial for increasing animal production efficiency through the application of improved nutrition. A large number of photographs illustrate nutritional deficiencies and conditions in tropical countries.This book contains 18 chapters concerned with the nutrition of grazing ruminants. The first chapter deals with the contributions, locations, and various types of ruminants and their importance to human welfare in the tropics and subtropics. Chapters 2 - 4 progress through nutrient requirements of grazing ruminants in warm climates, the effects of tropical heat on these requirements, and water requirements for ruminant species. Chapters 5 - 7 discuss grass and legume forage species suitable for tropical regions, pasture management procedures, and energy-protein supplementation programs needed during the extensive dry periods. The importance of tropical forages and soils toward meeting mineral requirements is discussed in Chapter 8. Chapters 9 -14 contain concise, up-to-date summaries of minerals emphasizing mineral status, incidence of mineral deficiencies and excesses in tropical regions, and benefits and methods of mineral supplementation for grazing ruminants are discussed in Chapters 15 - 17. Chapter 18 reviews vitamin nutrition considerations for ruminants consuming tropical forages.

  • The Initiation of DNA Replication

    • 1st Edition
    • Dan S Ray
    • English
    The Initiation of DNA Replication contains the proceedings of the 1981 ICN-UCLA Symposia on Structure and DNA-Protein Interactions of Replication Origins, held in Salt Lake City, Utah on March 8-13, 1981. The papers explore the initiation of DNA replication and address relevant topics such as whether there are specific protein recognition sites within an origin; how many proteins interact at an origin and whether they interact in a specific temporal sequence; or whether origins can be subdivided into distinct functional domains. The specific biochemical steps in DNA chain initiation and how they are catalyzed are also discussed. This book is organized into six sections and comprised of 41 chapters. The discussion begins by analyzing the replication origin region of the Escherichia coli chromosome and the precise location of the region carrying autonomous replicating function. A genetic map of the replication and incompatibility regions of the resistance plasmids R100 and R1 is described, and several gene products produced in vivo or in vitro from the replication region are considered. The sections that follow focus on the DNA initiation determinants of bacteriophage M13 and of chimeric derivatives carrying foreign replication determinants; suppressor loci in E. coli; and enzymes and proteins involved in initiation of phage and bacterial chromosomes. The final chapters examine the origins of eukaryotic replication. This book will be of interest to scientists, students, and researchers in fields ranging from microbiology and molecular biology to biochemistry, molecular genetics, and physiology.

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