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Books in Life sciences

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    • Practical Biostatistics

      • 1st Edition
      • July 26, 2012
      • Mendel Suchmacher + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 4 1 5 7 9 4 1
      • eBook
        9 7 8 0 1 2 4 1 5 8 5 7 3
      Evidence-based medicine aims to apply the best available evidence gained from the scientific method to medical decision making. It is a practice that uses statistical analysis of scientific methods and outcomes to drive further experimentation and diagnosis. The profusion of evidence-based medicine in medical practice and clinical research has produced a need for life scientists and clinical researchers to assimilate biostatistics into their work to meet efficacy and practical standards. Practical Biostatistics provides researchers, medical professionals, and students with a friendly, practical guide to biostatistics. With a detailed outline of implementation steps complemented by a review of important topics, this book can be used as a quick reference or a hands-on guide to effectively incorporate biostatistics in clinical trials.

    • Biotic Interactions and Soil-Borne Diseases

      • 1st Edition
      • Volume 23
      • December 2, 2012
      • A.B.R. Beemster + 5 more
      • English
      • Paperback
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      • eBook
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      This volume contains a collection of all the papers presented at the founding conference of the European Foundation for Plant Pathology, held from 26th February to 2nd March 1990 at Wageningen, The Netherlands. It focusses on the theme of "Biotic Interactions and Soil-Borne Diseases", on which there are contributions from leading European scientists in the field of soil-borne diseases. Ways of exploiting biotic processes and phenomena which result in plant production harmless to the environment are explored.

    • Handbook of Herbs and Spices

      • 1st Edition
      • August 13, 2012
      • K. V. Peter
      • English
      • Hardback
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      • Paperback
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      • eBook
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      Herbs and spices are among the most versatile ingredients in food processing, and alongside their sustained popularity as flavourants and colourants they are increasingly being used for their natural preservative and potential health-promoting properties. An authoritative new edition in two volumes, Handbook of herbs and spices provides a comprehensive guide to the properties, production and application of a wide variety of commercially-signifi... herbs and spices.Volume 1 begins with an introduction to herbs and spices, discussing their definition, trade and applications. Both the quality specifications for herbs and spices and the quality indices for spice essential oils are reviewed in detail, before the book goes on to look in depth at individual herbs and spices, ranging from basil to vanilla. Each chapter provides detailed coverage of a single herb or spice and begins by considering origins, chemical composition and classification. The cultivation, production and processing of the specific herb or spice is then discussed in detail, followed by analysis of the main uses, functional properties and toxicity.With its distinguished editor and international team of expert contributors, the two volumes of the new edition of Handbook of herbs and spices are an essential reference for manufacturers using herbs and spices in their products. They also provide valuable information for nutritionists and academic researchers.

    • Neurochemical Aspects of Hypothalamic Function

      • 1st Edition
      • December 2, 2012
      • L Martini
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 7 4 7 3
      • Hardback
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      • eBook
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      Neurochemical Aspects of Hypothalamic Function covers the proceedings of the Second International Meeting of the International Society for Neurochemistry, held in Milan, Italy, on September 1969. The one-day symposium focuses on the neurochemical aspects of hypothalamic function and their relation to secretion of anterior pituitary hormones. This book contains seven chapters that emphasize the relationships among the effects of environmental stimuli and observable changes in catecholamines in the hypothalamus, indoleamines in the pineal, the hypophysiotropic hormones of the hypothalamus, and secretion of anterior pituitary hormones. This text further explores some important interactions between the external environment, brain, and anterior pituitary, as well as feedback on the brain and anterior pituitary by body target organs, with a particular emphasis on their function as a unit. This book is an ideal source for neucochemists, neurologists, and researchers who are interested in the hypothalamic function.

    • Learning and Memory

      • 1st Edition
      • December 2, 2012
      • Joe L. Jr. Martinez
      • English
      • Paperback
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      • Hardback
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      • eBook
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      Learning and Memory: A Biological View is a comprehensive textbook about the neurobiology of learning and memory. Topics covered include developmental approaches to the memory process; anatomical correlates of neuronal plasticity; drugs that modulate learning and memory; and biochemical correlates of learning and memory. The link between aging and memory is also discussed, along with electrophysiological approaches to the study of memory. Comprised of 12 chapters, this book begins with a review of historical traditions that influenced research on the biological basis of learning and memory. Experimental findings suggesting that the engram for a simple classically conditioned skeletal response may be in the cerebellum are also presented. The next chapter emphasizes the importance of anatomical mechanisms that could mediate learning, plasticity, and memory storage in young and adult animals. Subsequent chapters explore the influence of peripheral hormones and particularly opioid peptides on complex behavior such as learning and memory; the contribution of individual neurotransmitter systems to learning; the psychopathology of aging; and long-term potentiation as a model of the way the central nervous system stores information. Learning in complex vertebrate systems and direct stimulation of various brain nuclei are also examined. The final chapter presents a neurobehavioral analysis of the structure of memory formation that utilizes lesions and explores human memory pathology. This monograph is intended for advanced undergraduate students, graduate students, and research workers in the field of memory.

    • Enzyme Catalysis and Regulation

      • 1st Edition
      • December 2, 2012
      • Gorden Hammes
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 5 0 5 9
      • eBook
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      Enzyme Catalysis and Regulation is an introduction to enzyme catalysis and regulation and covers topics ranging from protein structure and dynamics to steady-state enzyme kinetics, multienzyme complexes, and membrane-bound enzymes. Case studies of selected enzyme mechanisms are also presented. This book consists of 11 chapters and begins with a brief overview of enzyme structure, followed by a discussion on methods of probing enzyme structure such as X-ray crystallography and optical spectroscopy. Kinetic methods are then described, with emphasis on the general principles of steady-state and transient kinetics. The chemical principles involved in enzyme catalysis are also discussed, and case studies of a few well-documented enzymes are presented. The regulation of enzyme activity is analyzed from a nongenetic viewpoint, with particular reference to binding isotherms and models for allosterism. Two particular enzymes, aspartate transcarbamoylase and phosphofructokinase, are used as examples of well-studied regulatory enzymes. The last two chapters focus on multienzyme complexes and membrane-bound enzymes. This monograph is intended for graduate students, advanced undergraduates, and research workers in molecular biology and biochemistry.

    • Circulatory System Dynamics

      • 1st Edition
      • December 2, 2012
      • Abraham Noordergraaf
      • English
      • Paperback
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      • eBook
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      Circulatory System Dynamics reviews cardiovascular dynamics from the analytical viewpoint and indicates ways in which the accumulated knowledge can be expanded and applied to further enhance understanding of the normal mammalian circulation, to ascertain the nature of difficulties associated with disease, and to test the effect of treatment. Comprised of 10 chapters, this volume begins with an overview of the circulatory system, including its anatomy and the trigger for myocardial (heart muscle) contraction. The discussion then turns to measurement of blood pressure using invasive and non-invasive techniques; blood flow measurement, with emphasis on cardiac output and measurement in the microcirculation; the system and pulmonary arterial trees; and pulsatile pressure and flow in pulmonary veins. Subsequent chapters explore microcirculation and the anatomy of the microvasculature; the heart and coronary circulation, paying particular attention to the Frank-Starling mechanism and indices of myocardial "contractility"; and control of blood pressure, peripheral resistance, and cerebral flow. The last two chapters deal with circulatory assistance and the closed cardiovascular system. This book will be of interest to students, practitioners, and researchers in fields ranging from physiology and biology to biochemistry and biophysics.

    • Regulation of Ventilation and Gas Exchange

      • 1st Edition
      • December 2, 2012
      • Donald Davies
      • English
      • Paperback
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      • Hardback
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      • eBook
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      Regulation of Ventilation and Gas Exchange is a comprehensive account of the regulation of ventilation and gas exchange. Topics covered include central nervous system regulation of ventilation; ventilatory response to muscular exercise; respiratory control in air-breathing ectotherms; and breathing during sleep. Hydrogen ion homeostasis of the cerebral extracellular fluid is also discussed, along with specific mechanisms for O2 and CO transport in the lung and placenta. Comprised of nine chapters, this book begins with an overview of the neural elements that modify and/or are intrinsic to the respiratory rhythm. The next two chapters deal with the contribution of metabolic factors in the control of ventilation, paying particular attention to the importance of metabolic factors during muscular exercise and the specific role of ammonia in the regulation of respiration. A view of ventilatory control from a comparative standpoint, stressing both adaptive and mechanistic phenomena, is then presented. Subsequent chapters explore the regulation of breathing during sleep; regulation of cerebral extracellular fluid acid-base composition and its role in the control of ventilation and cerebral blood flow; carrier-mediated transport of respiratory gases; and measurement of ventilation-perfusio... ratios is presented. The last chapter considers lung surfactant mechanics and addresses issues such as in vitro vs in situ measurements of surface tension and the effects of surface tension on pulmonary vascular resistance and interstitial pressure. This monograph is designed not only for respiratory physiologists but also for students and researchers in other areas with an inclination toward respiratory physiology.

    • Immunological Properties of Protein Hormones

      • 1st Edition
      • December 2, 2012
      • Filippo Polvani
      • English
      • Paperback
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      • eBook
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      Immunological Properties of Protein Hormones covers the proceedings of the 1964 International Endocrinological Symposia on Immunological Properties of Protein Hormones, held in Rome, Italy. This symposium is organized under the auspices of Accademia Nazionale dei Lincei and of Consiglio Nazionale delle Rieerche Rome. This book is organized into four sections encompassing 27 chapters that tackle the immunological properties of gonadotropins, growth hormones, and insulin. The first section presents first an overview of immunological studies of protein hormones, followed by a discussion on the application of immunofluorescence to localization of pituitary hormones. This section also looks into the antigenic property of ACTH antibodies. The remaining sections cover the immunoassay methods of analysis, occurrence, distribution, clinical and physiological aspects, functions, and antigenic properties of the specific protein hormones. This book is of great benefit to immunoendocrinologis...

    • Current State of Alzheimer's Disease Research and Therapeutics

      • 1st Edition
      • Volume 64
      • July 24, 2012
      • English
      • Paperback
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      • Hardback
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      • eBook
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      This new volume of Advances in Pharmacology explores the Current State of Alzheimer's Disease Research and Therapeutics. Chapters cover such topics as the The role heat shock proteins play in the Alzheimer's Theater, Gamma-Secretase as a Target for Alzheimer's Disease, and Identification of protein kinase C for the treatment of dementias. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.

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