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Books in Life sciences

Criteria (Dose/Effect Relationships) for Organochlorine Pesticides
Report of a Working Group of Experts Prepared for the Commission of the European Communities, Directorate-General for Employment and Social Affairs, Health and Safety Directorate
1st Edition
October 22, 2013
M. Mercier
English
Criteria (Dose/Effect Relationships) for Organochlorine Pesticides presents the effect of organochlorine compounds on the immunological processes. This book deals with several organochlorine pesticides. Organized into 15 chapters, this book begins with an overview of the properties and toxicology of dichlorodiphenyl trichloroethane (DDT), a potent non-systemic stomach and contact insecticide of high persistence on solid surface. This text then examines the absorption, metabolism, and excretion of lindane in laboratory animals and in humans as well. Other chapters consider the studies on the carcinogenic potential as well as the mutagenic effects of dieldrin. This book discusses as well the metabolism and pharmacokinetics of endrin, which is a non-systemic and persistent insecticide used primarily on field crops. The final chapter deals with the need for further evaluation of any possible long-term risks to humans from the production and use of the technical product. This book is a valuable resource for agriculturists and research workers.
Pharmaceutical and Cosmetic Products for Topical Administration
Pharmaceutical Monographs
1st Edition
October 22, 2013
N. J. Van Abbé + 2 more
J. B. Stenlake
English
Pharmaceutical and Cosmetic Products for Topical Administration , Volume 9 provides the product characteristics, formulation, and rationale of topical therapeutic preparations. The book attempts to take the reader logically from the physiological and pathological aspects through to the reasoning behind topical medication. The text discusses such topics as the physiology and structure of the skin; the differential diagnosis of various skin diseases; the theoretical basis of emulsion technology; and the mechanism of percutaneous absorption. Undergraduate students and teachers of pharmacy and allied subjects will find the monograph very useful.
Pathobiology of Cell Membranes
Volume I
1st Edition
October 22, 2013
Benjamin F. Trump + 1 more
English
Pathobiology of Cell Membranes, Volume I, represents the first in a multivolume treatise designed for pathologists and cell biologists interested in the role of membrane alterations in disease processes. The treatise will emphasize concepts related to membrane alterations in cell injury as well as methods for elucidating such changes. The book begins with a discussion of the general conceptual aspects of cell injury and some details about the role of membrane alterations in the pathogenesis of both lethal and sublethal cellular reactions. This is followed by separate chapters on applications of circular dichroism to the study of membranes; a cell injury mechanism involving membrane components at the molecular level; and fundamental aspects of cell volume regulation and the modification of this regulation by primary or secondary damage of the cell membrane. Subsequent chapters deal with comparative roles of lysosomal and other membrane damage in cell injury; the role of membrane movements and various types of lysosome formation; toxic effects on mitochondrial membranes; and the concept of a biological membrane in health and disease at the tissue level.
Peripheral Dopaminergic Receptors
Proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology, Strasbourg, 24-25 July 1978
1st Edition
October 22, 2013
Jean Louis + 1 more
English
Peripheral Dopaminergic Receptors contains the proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology held in Strasbourg, France, on July 24-25, 1978. The papers explore advances that have been made in understanding peripheral dopaminergic receptors and cover topics organized around five themes: dopamine measurement; structure-activity relationships; peripheral actions of dopamine; effects of dopamine on the kidney; and the physiological role of dopamine in the autonomic nervous system. This volume is comprised of 36 chapters and opens with a discussion on the dopamine vascular receptor, along with its agonists and antagonists. The reader is then introduced to the physiological and clinical implications of free and conjugated dopamine; dopamine-sensitive adenylate cyclase in the renal artery of dogs; dopamine-induced relaxation of isolated dog arteries; and concentration and function of dopamine in normal and diseased blood vessels. The following chapters explore the possible involvement of endogenous substances in the cardiovascular actions of dopamine; the role of dopamine receptors as mediators of the neurogenic vasodilatation by dopaminergic agents; and implications of renal and adrenal dopamine for the role of conjugated dopamine. Studies on the peripheral cardiovascular activity of dopamine in the rat are also presented. This book will be of interest to practitioners in biosciences, pharmacology, physiology, and medicine.
The Clinical Significance of the Essential Biological Metals
1st Edition
October 22, 2013
I. J. T. Davies
English
The Clinical Significance of the Essential Biological Metals covers the six trace minerals necessary for human survival,namely zinc, copper, manganese, molybdenum, chromium, and cobalt. This book contains seven chapters that specifically discuss the effects of these minerals for enzyme function, protein synthesis, and their nutritional significance in veterinary and agricultural practice. Some of the topics covered in the book are the importance of interactions between the essential biological metals; importance of fertilizers; analysis of water supply, soil mineral content, and cancer mortality; influence of drinking water on atherosclerosis; non-essential but biologically important metals; and absorption and availability of zinc. Other chapters deal with the factors influencing absorption of zinc, the effects of copper on zinc availability, and the form and absorption of copper in the diet. A chapter is devoted to the role of lymphatics in copper absorption. Another chapter focuses on the distribution, absorption, and transport of manganese in the blood. The book can provide useful information to doctors, biochemists, nutritionists, students, and researchers.
Life Sciences and Space Research
Proceedings of the Open Meeting of the Working Group on Space Biology of the Twenty-First Plenary Meeting of COSPAR, Innsbruck, Austria, 29 May - 10 June 1978
1st Edition
October 22, 2013
R. Holmquist
English
Life Sciences and Space Research, Volume XVII contains the proceedings of the Open Meeting of the Working Group on Space Biology of the Twenty-first Plenary Meeting of COSPAR, held in Innsbruck, Austria, from May 29 to June 10, 1978 and of the Symposium on Gravitational Physiology which also took place in Innsbruck, Austria, on June 2 and 3, 1978. The papers review the results of research in the life sciences with respect to space biology, including chemical data returned from the Viking Lander experiments. The engineering design of biologically closed ecological systems suitable for very long term space flight or space colonies is also described. This volume is comprised of 41 chapters and begins with a discussion on closed regenerative life support systems for space travel and their implications for ecological science. Subsequent chapters examine closed ecology in space from a bioengineering perspective; technology requirements for nonterrestrial ecosystems; carbon suboxide polymer as an explanation for the wave of darkening observed on Mars; and volcanism and soil mercury on Mars, along with their consequences for terrestrial microorganisms. The next sections focus on the biology of extreme environments such as Central Antarctica, radiation biology in space, and gravitational physiology in relation to humans and animals. This book will be of interest to space scientists, space biologists, and those engaged in the life sciences, space research, molecular biophysics, biochemistry, and physiology.
Neurotransmission
Proceedings of the Sixth International Congress of Pharmacology
1st Edition
October 22, 2013
Liisa Ahtee
English
Neurotransmission is the second volume of the proceedings of the Sixth International Congress of Pharmacology, organized by the Finnish Pharmacological Society and held in Helsinki, Finland, on July 20-25, 1975. The papers focus on the developments in neurotransmission and cover topics ranging from novel transmitter substances and extraneuronal uptake of catecholamines to axonal transport mechanisms and nerve growth factor. This volume has 28 chapters divided into five sections. After discussing the possible functional role of certain tryptaminergic pathways, this book turns its attention to the metabolism of endogenous noradrenaline, with emphasis on the role of 3,4-dihydroxyphenylg... (DOPEG). The chapters that follow focus on amino acids as possible neurotransmitters, including histamine and glutamate. This text discusses as well the mechanisms underlying extraneuronal amine uptake and metabolism in the salivary glands; the effect of oxytetracycline on the responses of various tissue preparations to added noradrenaline and to field stimulation; and how axoplasmic transport is blocked by pharmacological agents. This book will be of interest to scientists representing all the major areas of pharmacology, including clinical pharmacology and toxicology, as well as interdisciplinary areas related to physiology, biochemistry, and endocrinology. Many of the topics will also appeal to internists, psychiatrists, neurologists, and anaesthesiologists.
The Nervous System
Autonomic Nervous System Drugs
1st Edition
October 22, 2013
Walter S. Root + 1 more
English
Physiological Pharmacology: A Comprehensive Treatise, Volume IV: The Nervous System — Part D: Autonomic Nervous System Drugs focuses on the effects of drugs on the nervous system, including how adrenergic drugs affect the heart and systemic circulation, metabolism, and adrenergic compounds. The selection first offers information on the effects of adrenergic drugs on the heart and systemic circulation. Topics include actions of adrenergic drugs, possible drug actions on the heart, epinephrine and arterenol, and other sympathomimetic drugs. The book then examines the effects of adrenergic compounds on pulmonary circulation, including physiologic considerations and general considerations of adrenergic compounds. The manuscript ponders on the effects of adrenergic agents on smooth muscles other than those of the vascular system and the effects of sympathomimetic amines and adrenergic blocking agents on metabolism. The book also touches on veratrum alkaloids and neurotoxins, as well as botulism, tetanus, therapeutic use, and chemistry of veratrum alkaloids. The selection is a dependable reference for readers interested in the effects of drugs on the nervous system.
Pharmacology of Histamine Receptors
1st Edition
October 22, 2013
C. R. Ganellin + 1 more
English
Pharmacology of Histamine Receptors presents a summary of the pharmacology of histamine receptors. It discusses the research and developments made in the use of histamine. It addresses the biological actions of the drug in various pathological instances. Some of the topics covered in the book are the classification of histamine receptors; mepyramine and related histamine antagonists; activity relationships of drugs acting at histamine receptors; chemical structure of histamine; effects of methyl substituents in histamine; enzymes involved in histamine metabolism; and histamine in body fluids. The cellular sources of histamine in tissues and blood are fully covered. The relationship of the mast cell to basophil is discussed in detail. The text describes in depth the urinary excretion of histamine and metabolites. The pathological conditions in man are presented completely. A chapter is devoted to the fundamental properties of adenylate cyclase and its measurement. The book can provide useful information to pharmacists, doctors, chemists, students, and researchers.
The Brain as a Computer
International Series of Monographs on Pure and Applied Biology: Zoology
1st Edition
October 22, 2013
F. H. George
G. A. Kerkut
English
The Brain as a Computer, Second Edition is a 14-chapter book that outlines the principles of cybernetics in relation to behavior, from the perspective of experimental psychology and neurophysiology. This book begins by describing the main ideas of cybernetics. Subsequent chapters explore cybernetic models, with emphasis on finite automata, and particularly finite automata in logical net form, which seem especially useful to the modeling of behavior. Other chapters summarize learning theory, neurological matters, thinking, perception, and artificial intelligence.

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