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Elsevier

Books in Life sciences

  • Discovery of Novel Natural Products with Therapeutic Potential

    • 1st Edition
    • Vincent P. Gullo
    • English
    Although science has discovered effective drugs for many of the diseases that afflict mankind, many human health problems remain untreatable. The search for novel therapeutic agents is always ongoing. This book will describe some of the diverse sourcesof natural products, such as terrestrial and marine environments; and will review how research has increased knowledge of biological systems and human disease, leading to the design of targeted asssays, amenable to high volume screening.

  • Data Acquisition and Processing

    In Biology and Medicine
    • 1st Edition
    • Kurt Enslein
    • English
    Data Acquisition and Processing: In Biology and Medicine, Volume 2 records the proceedings of the 1962 Rochester Conference on Data Acquisition and Processing in Biology and Medicine. The conference explores the utilization, viability, and implication of electronic data processing in the field of bio-medicine. The compendium encompasses the developments in electronic data processing in relation to its wide application to medicine and life sciences. The conference is organized so that experts in the various fields of medicine and biology, along with computer science and systems experts, present and develop ideas, technologies, and methods they can effectively use in their line of work. The conference devotes sessions to discuss relevant topics in medical research and analysis; research and development of medical information retrieval projects; digital and analog computation considerations for biomedical problems; and the use of statistical decision functions in medical diagnosis. The book will be interesting to physicians, medical researchers, computer and systems experts, specialists in the life sciences, and workers in the pharmaceutical industry.

  • Pain Syndromes in Neurology

    Butterworths International Medical Reviews
    • 1st Edition
    • Howard L. Fields
    • English
    Pain Syndromes in Neurology deals with the diagnosis and treatment of painful conditions associated with dysfunction of the peripheral or central nervous system. It discusses advances in three areas: first, the normal anatomy and physiology of pain; second, the pathophysiology of damaged sensory neurons; and third, the diagnosis and treatment of patients with neuropathic pain. The book begins with a discussion of neural mechanisms relevant to pain perception along with a brief review of neuropathic pain. This is followed by separate chapters on hyperalgesia following cutaneous injury; the importance of peripheral processes in the etiology of neuropathic and radiculopathic pain; and mechanisms by which sympathetic efferent fibers contribute to the occurrence of pain. Subsequent chapters cover the diagnosis and treatment of reflex sympathetic dystrophy; pain in generalized neuropathies; surgical treatment of pain; clinical features and management of postherpetic neuralgia; diagnosis of cancer pain syndromes; and drugs in the management of chronic pain.

  • The Flowering Process

    • 1st Edition
    • Frank B. Salisbury
    • P. F. Wareing + 1 more
    • English
    The Flowering Process covers the physiological processes involved in the conversion from the vegetative to the reproductive state in higher plants. This book is composed of ten chapters, and begins with a description of the biological framework of flowering. The succeeding chapters deal with the link between ecology and the flowering process and the low temperature promotion of flowering. These topics are followed by discussions on methods of experimentation with cocklebur and the preparation of plant for response to photo period. Other chapters describe the effect of light, pigment, and timing on flowering process. The final chapters consider the synthesis, movement, and action of the flowering hormone. This book will prove useful to graduate students with subjects related to the mechanisms of flowering.

  • Computers and Computations in the Neurosciences

    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 10: Computers and Computations in the Neurosciences discusses the use of computers in the neurosciences. The book deals with data collection, analysis, and modeling, with emphasis on the use of computers. Section I involves data collection using a personal microcomputer system. One paper presents a tutorial on using a PC-based motor control composed of an electronic circuit to adjust the motion of a light microscope stage through a software program. Other papers discuss computer methods in nuclei cartography and a computer-assisted quantitative receptor autoradiography in studying receptor density distribution. Section II deals with data analysis and some computer programs for kinetic modeling of gene expression in neurons. The book also discusses a computerized analysis of opioid receptor heterogeneity by ligand binding in test animals using computerized programs instead of employing manual or graphical methods. Computerized curve-fitting allows the researcher to utilize a more precise mathematical model to describe the binding of one ligand to one class of sites. Section III evaluates data modeling and simulations and describes the practicality of using computers to design model ion channels. Another paper discusses a graphical interaction program called MEMPOT to simulate an electrophysiological investigation of the properties of the membrane potential in stimulated cells. The book also presents a quantitative data gathered from computer simulation of the factors that affect neuronal density per measured sections. The book is suitable for microbiologists, biochemists, neuroscientists, and researchers in the field of medical research, as well as for advanced computer programmers in medical research work.

  • Clostridium Difficile

    Its Role in Intestinal Disease
    • 1st Edition
    • Rial D. Rolfe
    • English
    Despite the tremendous progress made during the last few years in understanding the pathogenesis, epidemiology, diagnosis, and treatment of Clostridium difficile-associated intestinal disease, many extremely important and fundamental questions remain to be answered. The objectives of this book are to summarize the available information regarding Clostridium difficile and its role in intestinal disease and to serve as a basis for future investigations in this challenging area.Clostridium difficile: its role in Intestinal Disease. An excellent volume that should appeal not only to the devotee of C difficile but to all gastroenterologists and microbiologists, this will not languish on my library shelves like so many other books I have reviewed. It will be regularly thumbed. --R.H. George, consultant microbiologist, Children's Hospital, BirminghamClostridiu... difficile: Its Role in Intestinal disease. The book is well written and informative; it has a vast amount of information packed in it...this book would be a welcome addition to the researchers and clinicians interested in C difficile-associated intestinal diseases. --Edward Balish, University of Wisconsin Medical School

  • Developmental Neuropsychobiology

    • 1st Edition
    • William T Greenough + 1 more
    • English
    Developmental Neuropsychobiology is a compendium of papers that deals with developmental neuroscience and developmental psychology, as well as the broad range of approaches toward brain-behavior development. One paper reviews the embryonic mechanisms including the pattern formation that develops in a single fertilized egg, particularly focusing on limb innervation as a special case of pattern formation. Another paper discusses the regulation of nerve fiber elongation during embryogenesis. One author analyzes the pathways and changing connections in the nervous system of the insect: he shows that manipulating neural organization by grafting results in the ability of the transplanted sensory cells to find the proper central connections. Another paper reviews the sex differences in developmental plasticity of behavior and the brain. These differences point to the vulnerability of males during development to incidences of autism, dyslexia, or cerebral palsy compared to females. One paper also examines alternative perceptions of parent- offspring relationships. This collection can prove helpful for researchers, students, and academicians involved in the disciplines of biological or psychological sciences.

  • Biotechnology of Filamentous Fungi

    Technology and Products
    • 1st Edition
    • David B. Finkelstein
    • English
    Biotechnology of Filamentous Fungi: Technology and Products provides a comprehensive discussion of the molecular biology, genetics, and biochemistry of filamentous fungi. It also deals with general principles of biochemical engineering such as process design and scaleup. The book's main emphasis, however, is on the commercial significance of filamentous fungi. The book highlights the unique aspects of filamentous fungi along with those aspects common to most microorganisms studied in industries that use biotechnology. Filamentous fungi can generate a wide range of industrial products including primary metabolites such as organic acids, secondary metabolites such as β-lactam antibiotics, nonantibiotic drugs, and enzymes for use in food production. Whole organisms such as mushrooms can be used as well as organisms used as insecticides and herbicides. Filamentous fungi also qualify as potential hosts for the secretion of certain heterogeneous proteins such as mammalian proteins. However, not all things related to fungi are beneficial. Mycotoxins products by fungi can be lethal to humans; there is also a need to develop antifungal agents to destroy fungi that can kill animals and plants. These topics are important aspects of the biotechnology of filamentous fungi and are dealt with in this text.

  • Instinctive Living

    A Study of Invertebrate Behaviour
    • 1st Edition
    • Theodore Savory
    • J. F. Harris + 2 more
    • English
    Instinctive Living: A Study of Invertebrate Behaviour discusses the behaviors of some invertebrate animals. The book is divided into nine chapters; the first two chapters discuss the active invertebrate and environment. Then, the text elaborates on the movement, kineses, and taxes of these animals, as well as their responses to stimuli. These mechanisms are known as reflex or reflex actions. The latter parts discuss in detail the invertebrate mind and behavior. This text will be invaluable to zoologists, general scientists, and those interested in studying animals, specifically the invertebrates.

  • Off-Flavors in Foods and Beverages

    • 1st Edition
    • Volume 28
    • G. Charalambous
    • English
    This book, volume 28 in the Developments in Food Science Series, reviews thelatest information and up-to-date concepts concerning a great number ofaspects of flavor quality. Particular attention has been afforded to providea balance between food and beverage chemistry, biochemistry, microbiology,nutriti... processing, packaging, storage, computer applications, andchemometrics.Twen... six specialists were invited to discuss the present state of knowledgein their particular fields. Together with their co-workers (totalling oversixty well known researchers) the authors were drawn from the internationalspectru... of academia, government institutes, and industry. Their presentationsinclude... original research results, background reviews, and comprehensivebibliog... informative and well documented book goes a long way to improving thecurrent knowledge in a complex area and certainly increase understanding of taste and odor, flavors and off-flavors of high quality foods and beverages.

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