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Elsevier

Books in Life sciences

  • Transgenesis and Targeted Mutagenesis in Immunology

    • 1st Edition
    • English
    Investigations into the field of immunology are rapidly expanding with the use of genetically altered mice at the embryonic stage. This breakthrough laboratory guide provides a complete study of transgenesis and targeted mutagenesis in laboratory mice that will be valued by researchers looking for fresh observations and interpretations when designing future experiments.

  • Guide to Biochemistry

    • 1st Edition
    • James C. Blackstock
    • English
    Guide to Biochemistry provides a comprehensive account of the essential aspects of biochemistry. This book discusses a variety of topics, including biological molecules, enzymes, amino acids, nucleic acids, and eukaryotic cellular organizations. Organized into 19 chapters, this book begins with an overview of the construction of macromolecules from building-block molecules. This text then discusses the strengths of some weak acids and bases and explains the interaction of acids and bases involving the transfer of a proton from an acid to a base. Other chapters consider the effectiveness of enzymes, which can be appreciated through the comparison of spontaneous chemical reactions and enzyme-catalyzed reactions. This book discusses as well structure and function of lipids. The final chapter deals with the importance and applications of gene cloning in the fundamental biological research, which lies in the preparation of DNA fragments containing a specific gene. This book is a valuable resource for biochemists and students.

  • Thrombosis and Bleeding Disorders

    Theory and Methods
    • 1st Edition
    • Nils U. Bang + 2 more
    • English
    Thrombosis and Bleeding Disorders compiles the laboratory and research aspects of thrombosis and hemorrhagic disorders in humans. This book presents reviews of the underlying theory, physiology, and biochemistry of hemostasis and thrombosis, including the enzymology of blood coagulation and fibrinolysis. This compilation is divided into three levels of specific purposes. First is to provide the most reliable and widely accepted laboratory assays of undisputed diagnostic clinical value, which provides newcomers in the field and experienced workers in the coagulation laboratory with a reference manual to everyday work in a clinically-oriented environment. Second is to review and sketch in outline the theoretical sections focusing on mechanisms. Finally, this text aims to include a systematic review of the most successful purification techniques for individual coagulation factors and moieties of the fibrinolytic enzyme system. This publication is beneficial to medical students and clinicians concerned with human blood coagulation.

  • Bacterial Metabolism

    • 1st Edition
    • H. W. Doelle
    • English
    Bacterial Metabolism focuses on metabolic events that occur in microorganisms, as well as photosynthesis, oxidation, polysaccharide formation, and homofermentation. The book first discusses the thermodynamics of biological reactions, photosynthesis and photometabolism, and chemosynthesis. Free energy, photosynthesis, enzymes, and terminology in bacterial metabolism are elaborated. The manuscript then examines acetic acid bacteria and lactic acid bacteria. Discussions focus on lactate, ethanol, glucose, and glycerol metabolism, glycol oxidation, homofermentation, polysaccharide formation, and electron transport systems. The publication takes a look at pseudomonadaceae and nitrogen metabolism as an energy source for anaerobic microorganisms. Topics include metabolism of pairs of amino acids, single amino acid metabolism, oxidation of glycolate and malonate, and oxygenases. The book is a dependable source of information for readers interested in bacterial metabolism.

  • Sex Chromosomes

    • 1st Edition
    • Ursula Mittwoch
    • English
    Sex Chromosomes focuses on the study of sex chromosomes, including human chromosomal abnormalities, behavior and characteristics of chromosomes, and cell division. The book first offers information on the chromosomal basis of sex determination, as well as development of the cell theory, mitosis, fertilization, meiosis, and discovery of sex chromosomes. The publication also ponders on the mitosis, meiosis, and formation of gametes. Discussions focus on the special characteristics of sex chromosomes, abnormalities of cell division, and sexual differentiation. The manuscript reviews sex chromosomes in plants, Drosophila, and Lepidoptera. The book also examines sex-chromosome mechanisms that differ the classic type; sex chromosomes in fishes, amphibia, reptiles, and birds; and sex chromosomes in man. Discussions focus on normal human sex chromosomes, Turner's syndrome, Klinefelter's syndrome, true hermaphrodites, testicular feminization, and pseudohermaphrodites... Sex chromosomes in mammals other than man, including monotremata, marsupialia, insectivora, rodentia, and carnivora, are discussed. The publication is a dependable reference for readers interested in the study of sex chromosomes.

  • Current Topics in Bioenergetics

    Volume 10
    • 1st Edition
    • D. Rao Sanadi
    • English
    Current Topics in Bioenergetics, Volume 10 provides information pertinent to the developments in the study of dynamic mechanisms in functioning muscle by following fluctuations in kinetic states. This book explores the method that permits analysis of cyclic rotational motions in cross-bridge formation and has considerable potential in other bioenergetics systems. Organized into six chapters, this volume begins with an overview of the structure and function of muscles. This text then examines the bioenergetic aspects of nitrogen fixation. Other chapters consider one aspect of the regulation of the in vivo activity of organelles, namely, the regulation of mitochondrial activities at the level of substrate. This book discusses as well the status of the controversial findings on the proton–oxygen ratios in mitochondria and the mechanism of H+ pumping in oxidative reactions. The final chapter deals with the usefulness of bacterial mutants in the study of cell metabolism. This book is a valuable resource for biologists and biochemists.

  • Perspectives in Virology

    Antiviral Mechanisms
    • 1st Edition
    • Volume 9
    • Morris Pollard
    • English
    Perspectives in Virology IX: Antiviral Mechanisms is a collection of scientific papers presented at the Ninth Gustav Stern Symposium on Perspectives in Virology: Antiviral Mechanisms, held at Notre Dame, Indiana in February 1974. The majority of the papers in this volume concentrate on the different ways the human body defends itself against viral attack. Others deal with artificial means of interfering with the life cycle of viruses. Topics covered in this compendium include defective interfering (DI) particles as antiviral agents; detection and identification by immune electron microscopy of fastidious agents associated with respiratory illness, acute nonbacterial gastroenteritis, and hepatitis A; and synthetic vaccines. Cellular immune response in viral infections; transfer factor and cellular immunity to viral infection; and studies on adenine rabinoside are presented as well. Virologists, microbiologists, pathologists, pharmacologists, and researchers in the fields of medicine and pathology will find the book insightful and informative.

  • Bacterial Physiology and Metabolism

    • 1st Edition
    • J. R. Sokatch
    • English
    Bacterial Physiology and Metabolism focuses on research on bacteria, as well as metabolism of carbohydrates, fermentation, and oxidation of acids. The book first offers information on nutrition and growth of bacterial cultures, including requirements for growth, nutritional classification of bacteria, measurement of bacterial growth, and synchronous growth of bacterial cultures. The manuscript then considers the chemical composition of bacteria, oligosaccharide catabolism, and transport of sugars. The publication takes a look at the fermentation of sugars and aerobic metabolism of carbohydrates. Discussions focus on Embden-Meyerhof fermentations, miscellaneous pathways, and hexose, pentose, polyol, and hexuronic acid oxidation. The text also elaborates on oxidation of organic acids, electron transport, oxidation of hydrocarbons, and protein and amino acid catabolism. The text is a dependable reference for readers interested in bacterial physiology and metabolism.

  • Handbook of Amylases and Related Enzymes

    Their Sources, Isolation Methods, Properties and Applications
    • 1st Edition
    • The Amylase Research Society The Amylase Research Society o
    • English
    This handbook, published to mark the 20th anniversary of The Amylase Research Society of Japan, presents a concise account of the properties and applications of amylases and related enzymes. Enzymes are discussed with reference to their source, isolation method, properties, inhibition, kinetics and protein structure. This information is then applied in the description and interpretation of their use in industry. As well as amylases, other enzymes capable of catalyzing reactions with starch and glycogen, and the further conversion of amylase reaction products for industrial applications are discussed. The text is supported by numerous explanatory figures and tables, and each section is fully referenced.

  • Clinical Immunobiology

    • 1st Edition
    • Volume 3
    • Fritz H. Bach + 1 more
    • English
    Clinical Immunobiology, Volume 3 covers a variety of methods used for assaying the immune status of an individual. This volume is composed of 21 chapters and begins with a presentation of the background and issues to which clinical tests would be applied. The succeeding chapters outline the methodological procedures used in the analyses. Other chapters present some examples of the kinds of data that can be generated with the procedures used and provide guidelines for interpretation of the tests. The remaining chapters discuss the value of the immunological test procedures in differential diagnosis and analysis of diseases. These chapters also explore the usefulness of these procedures in prognosis of disease and the consequences of immunological manipulation undertaken for treatment or prevention of disease. This book will be of great value to clinical immunobiologists, biochemists, and researchers.

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