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Elsevier

Books in Life sciences

  • Three Dimensional Microanatomy of Cells and Tissue Surfaces

    Proceedings of the Symposium on Three Dimensional Microanatomy held in Mexico City, Mexico, August 17-23, 1980
    • 1st Edition
    • Delmas J. Allen + 2 more
    • English
    Three Dimensional Microanatomy of Cells and Tissue Surfaces focuses on the use of scanning electron microscopy in the study of the microanatomy of cells and tissues, cell relationships, and complex biological relationships. The selection first elaborates on the technical aspects of stereoprojection for electron microscopy; three-dimensional microanatomy of intracellular structures; microcirculation studies by the injection-replica method with special reference to portal circulations; and three-dimensional architecture of the mammalian liver. Discussions focus on the preparation of vascular casts, portal circulations of various organs, scanning electron microscopy, copying and printing stereopair negatives, stereoprojection, and high voltage electron microscopy. The text then takes a look at scanning electron microscope bloodvessel casts analysis, three dimensional microanatomy of reticular tissues, kidney glomerular epithelium in response to different physiological states and experimental conditions, and mammalian renal papilla and pelvis. The manuscript examines the lung in scanning electron microscopy and stereopresentation, surface topography of endocardial endothelium, scanning electron microscopy of endothelium, human vas deferens, and seminal vesicles, and dynamic morphology of the apical membrane of lactating cells viewed by freeze-fracture. The selection is a valuable reference for researchers interested in the use of scanning electron microscopy in the study of the microanatomy of cells and tissues and biological relationships.

  • Centrifugal Separations in Molecular and Cell Biology

    • 1st Edition
    • G.D. Birnie + 1 more
    • English
    Centrifugal Separations in Molecular and Cell Biology focuses on the application of modern centrifugation technology in molecular and cell biology, including the separation and fractionation of biological particles by centrifugation on the preparative and analytical scales. The selection first covers the principles and practices of centrifugation and the bases of centrifugal separations. Discussions focus on the basic concepts of sedimentation theory, centrifugation methods, designing centrifugation experiments, care of centrifuges and rotors, and statistical estimation of molecular parameters. The book also ponders on the practical aspects of rate-zonal centrifugation, including gradient materials, density and viscosity of glycerol solutions, and resolution and gradient shape. The publication examines fractionations in zonal rotors and the quantitative aspects of rate-zonal centrifugation. The text then reviews isopycnic centrifugation in ionic media and analytical centrifugation. Topics include separation by isopycnic banding, large-scale preparative procedures, and density-gradient solutes. The selection is a valuable reference for readers interested in centrifugation technology.

  • The Biological Clock

    Two Views
    • 1st Edition
    • Frank A. Brown + 2 more
    • English
    The Biological Clock describes the rhythmic processes in a great variety of plants and animals. This book is an outgrowth of the 1969 James Arthur Lecture Series on "Time and its Mysteries" held at New York University. This three-chapter work begins with the basic principles of biological rhythms and clocks, along with various diagrams to illustrate some aspects of circadian rhythms in animals. The second chapter discusses the hypothesis of environmental timing of the clock. This chapter explores numerous research studies on phenomenon of biological rhythms, the nature of the rhythmic mechanism, and hormonal regulation. The third chapter examines the cellular-biochemical clock hypothesis and its contribution in the progress of understanding the complexity of biological rhythm. This book is intended primarily for biologists, behaviorists, and researchers.

  • Enzymes of the Arterial Wall

    • 1st Edition
    • John Esben Kirk
    • English
    Enzymes of the Arterial Wall is a comprehensive up-to-date monograph, and is the first publication dealing specifically with quantitative determinations of enzyme activities in human and animal vascular tissue. All available information concerning this subject is included. This summary of all current knowledge will be very useful to scientists who lack extensive library facilities and knowledge of foreign languages necessary for a thorough and time-consuming personal search of the original literature. A systematic description is made of 98 different enzymes; nearly all enzymes in the carbohydrate metabolic pathways are included. Brevity of discussion has made it possible to incorporate all available data. The results represent 27,200 quantitative biochemical assays performed with reliable analytical techniques on both normal and arteriosclerotic tissue; 70 enzymic procedures are described. The framework for the arrangement of facts throughout the book was designed to make information easily accessible. Each enzyme is described separately, using the sequence of The Commission on Enzymes of The International Union of Biochemistry, and is followed by literature references with full titles.

  • Immunological Methods

    • 1st Edition
    • Ivan Lefkovits + 1 more
    • English
    Immunological Methods a compendium of basic research techniques being used in one of the largest immunology research institutes, the Basel Institute for Immunology, with particular emphasis given to new methodology. The procedures have been described by individuals judged to be highly expert in their specialties. In many instances the methods developed or adapted to unique uses by the contributors have not previously been described in detail. The book contains 34 chapters covering techniques for detection, isolation, and purification of antibodies (including dansylation, two-dimensional chromatography, isoelectric focusing, polyacrylamide gel electrophoresis, and isotachophoresis); measurement of equilibrium constants (equilibrium dialysis, filtration, and sedimentation); and isotope and fluorescent labeling and detection of cell-surface components. Techniques such as isotope laboratory maintenance; chemical modification of proteins, haptens, and solid supports, and haptenation of viable biological carriers; production of antisera against allotypes and histocompatibility antigens and production of antibody with clonai dominance; histocompatibility and MLR testing; and cell separation by haptenated gels and by velocity sedimentation of rosette-forming cells are also discussed. Other chapters cover detection of antibody-secreting and alloantigen-binding cells; immune responses in vitro and their analysis by limiting dilution; production of T-cell factors; hybridoma production by cell fusion; maintenance of cell lines and cloning in semisolid media; and the mathematical analysis of immunological data.

  • Microbiology in Clinical Practice

    • 2nd Edition
    • D. C. Shanson
    • English
    Microbiology in Clinical Practice presents the infections and syndromes caused by micro-organisms. It discusses the management of infective diseases and aetiological agents. It addresses the latex agglutination, immunofluorescent, monoclonal antibody, and nucleic acid probe investigations. Some of the topics covered in the book are the classification and pathogenicity of microbes; classification of bacteria; classification of viruses; classification of fungi; general principles of antimicrobial chemotherapy; antibiotic sensitivity tests; procedures in the laboratory for microbiological diagnosis; and the mode of action of antimicrobial drugs. The resistance to antimicrobial drugs are covered. The microbiological investigations of septicaemia are discussed. The text describes the human immunodeficiency virus infection and AIDS in infants. A study of the congenital immunodeficiency and impaired resistance to infection is presented. A chapter is devoted to the predisposing factors for anaerobic infections. Another section focuses on the infections of the central nervous system. The book can provide useful information to doctors, pathologists, neurologists, students, and researchers.

  • Biotechnology of Blood

    • 1st Edition
    • Jack Goldstein
    • English
    Biotechnology of Blood presents research on applications of biotechnology to blood and its components. The book is organized into four parts. Part I begins with an overview of the blood business in order to provide background of the industry, to identify problems, and perhaps some solutions that rely on the scientific advances made possible by biotechnology. This is followed by studies on the storage and preservation of red blood cells; autologous blood salvage procedures; the development procedures to provide a constant supply of blood group O; and the development of blood substitutes. Part II on plasma fractions includes studies on the preparation of plasma fractions, recombinant antihemophilic factors, and fibrinogen. Part III on the regulation of blood cell products includes studies such as hematopoietic stem cell processing and storage; and long-term bone marrow cell cultures. Part IV on blood-borne diseases examines the inactivation of viruses found with plasma proteins and viruses found with cellular components.

  • The Oxygen Evolving System of Photosynthesis

    • 1st Edition
    • Yorinao Inoue + 2 more
    • English
    The Oxygen Evolving System of Photosynthesis documents the proceedings of an international symposium entitled ""Photosynthetic Water Oxidation and Photosystem II Photochemistry,"" held at The Institute of Physical and Chemical Research (RIKEN), Wako, Saitama, Japan, 15-17 March 1983. Several other papers from authorities in this field are also included. This book provides in a systematic fashion the most current thoughts and insights into the field of photosynthetic oxygen evolution. The volume contains 46 chapters organized into five parts. Part I deals with the subunit structure of photosystem II reaction center pigment proteins and the charge separation (generation of positive and negative charges, P680+ and Pheo-). Part II examines the components and their function on the donor side. Part III discusses the biochemistry of the water oxidation enzyme system, polypeptide composition, and functional reconstitution. Part IV take up the functions of chloride and bicarbonate in electron transport and the mechanism of photoactivation in latent or Tris-inactivated chloroplasts. Part V discusses the fate of reducing equivalents going through the two-electron gate mechanism, together with the biochemistry of the quinone components on the acceptor side.

  • Raw Materials Purchasing

    An Operational Research Approach
    • 1st Edition
    • Volume 4
    • B. G. Kingsman
    • English
    A systematic study of commodity purchasing analysed from an operational research viewpoint and based on numerous case studies.

  • Insecticides

    Action and Metabolism
    • 1st Edition
    • R. D. O'Brien
    • English
    Insecticides: Action and Metabolism provides a comprehensive review of the action of insecticides and a survey of their metabolism. This book discusses the toxicology of insecticides. Organized into 17 chapters, this book begins with an overview of the mechanisms whereby toxicants exert their effects. This text then discusses the insecticidal action of organophosphates, which is described as the toxic organic compounds containing phosphorus. Other chapters consider the mode of action of organophosphates by inhibiting cholinesterase with consequent disruption of nervous activity caused by accumulation of acetylcholine at nerve endings. This book discusses as well the erratic patterns of selective toxicity to insects of the carbamates. The final chapter deals with the real hazard to human health as well as the effects upon wild life of insecticides and chlorinated pesticides. This book is a valuable resource for organic and agricultural chemists, as well as biologists, agriculturists, neurophysiologists, environmental scientists, and research workers.

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