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Books in Life sciences

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    • Control of Energy Metabolism

      • 1st Edition
      • May 12, 2014
      • Britton Chance + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 5 4 8 6 9
      • eBook
        9 7 8 1 4 8 3 2 7 1 6 6 8
      Control of Energy Metabolism: A Colloquium of the Johnson Research Foundation focuses on the processes, reactions, and approaches involved in the control of energy metabolism. The selection first offers information on the respiratory chain as a model for metabolic control in multi-enzyme systems, dynamics and control in cellular reactions, and computer-based analysis of biochemical data. The text then explores purification and properties of rabbit skeletal muscle phosphofructokinase; multiple forms of heart phosphofructokinase; and mechanisms of inhibition and activation of phosphofructokinase in Novikoff ascites tumor cells. Discussions focus on the properties of purified phosphofructokinase; effect of heart extracts on reactivation of phosphofructokinase; active and inactive forms of phosphofructokinase; and effect of hexose phosphate and adenylic nucleotides on reactivation of phosphofructokinase. The manuscript takes a look at enzyme and metabolite profiles; coordinated stimulation of hexokinase and phosphofructokinase by phosphate in a reconstituted system of glycolysis; control of hexokinase in ascites tumor glycolysis; and cation flux across the mitochondrial membrane as a possible pacemaker of tissue metabolism. The selection is a vital reference for biochemists and researchers interested in the control of energy metabolism.

    • Mechanisms of Eukaryotic DNA Recombination

      • 1st Edition
      • June 28, 2014
      • Max E Gottesman + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 9 6 4 4
      • eBook
        9 7 8 1 4 8 3 2 7 4 0 8 9
      Mechanisms of Eukaryotic DNA Recombination is a collection of papers that discusses advances in eukaryotic genetic recombination. Papers address issues in eukaryotic genetic recombination, particularly DNA integration in mammalian genomes, genetic recombination in Drosophila or Caenorhabditis; the manipulation of the mouse genome; genome organization; and genetic recombination in protozoa. One paper discusses chromatid interactions during intrachromosomal recombination in mammalian cells, namely, intrachromatid and sister chromatid. Another paper analyzes the implication for chromosomal recombination and gene targeting; results on extrachromosomal recombination show that circles are inefficient substrates for recombination even if only one of two substrates in an intermolecular reaction is circular. One author discusses the genetics and molecular biology of recombination, citing the work of Watson and Crick, stating that crossing-over occurs between genes (not within them). He also explains that the formation and resolution of recombination intermediaries depend on enzyme or other proteins. This book will prove invaluable to cellular biologists, microbiologists, and researchers engaged in genetics and general biology.

    • The Provision and Use of Library and Documentation Services

      • 1st Edition
      • May 16, 2014
      • W. L. Saunders
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 0 1 3 8
      • eBook
        9 7 8 1 4 8 3 1 8 5 9 4 1
      The Provision and Use of Library and Documentation Services is a collection of papers that deals with library interdependent considerations of use and service. One paper discusses the value, organization, and exploitation of trade literature, citing the importance of maintaining a file of trade catalogues to narrow the gap between industrial activity and academic research. Another paper reports a high library membership (80% - 100%) on a survey of library provision and services in four correctional institutions in London. The author notes that professional advice should also be available to help the prisoner read effectively. One author reviews the library services for undergraduates particularly problems of inadequate services and facilities. Other authors discuss the pattern of borrowing in several libraries which generalizes the borrowing behavior of academic communities, such as the rising levels of foreign language and "off-subject" borrowing. Of interest is one author's analysis of the way scientists use libraries in terms of finding information, reading, and use of facilities. His conclusion: scientists have no clear-cut opinion on the best method of acquiring information. This book is suitable for librarians, administrators of private or public library systems, for students and academicians in the field of library science.

    • Protides of the Biological Fluids

      • 1st Edition
      • Volume 33
      • November 26, 2014
      • H. Peeters
      • English
      • eBook
        9 7 8 1 4 8 3 2 7 9 7 6 3
      An International Review Series Devoted to Proteins and Related Studies, Volume 33: Protides of the Biological Fluids documents the proceedings of the 33rd Colloquium held in 1985. This book is divided into three sections. Section A focuses on the plasma protein genes that includes the location of genes on the chromosome, pathology and variance of several genes, and gene expression. The proteins of the nucleus and detection of antibodies, such as antinuclear antibodies (ANA), to nuclear constituents are deliberated in Section B. Section C is devoted to the technical advances in the field of protein chemistry. This book is a good reference for students, researchers, and medical practitioners conducting work on the protides of biological fluids.

    • Insecticides

      • 1st Edition
      • June 28, 2014
      • R. D. O'Brien
      • English
      • Paperback
        9 7 8 1 4 8 3 2 5 0 6 3 2
      • eBook
        9 7 8 1 4 8 3 2 7 0 6 8 5
      Insecticides: Action and Metabolism provides a comprehensive review of the action of insecticides and a survey of their metabolism. This book discusses the toxicology of insecticides. Organized into 17 chapters, this book begins with an overview of the mechanisms whereby toxicants exert their effects. This text then discusses the insecticidal action of organophosphates, which is described as the toxic organic compounds containing phosphorus. Other chapters consider the mode of action of organophosphates by inhibiting cholinesterase with consequent disruption of nervous activity caused by accumulation of acetylcholine at nerve endings. This book discusses as well the erratic patterns of selective toxicity to insects of the carbamates. The final chapter deals with the real hazard to human health as well as the effects upon wild life of insecticides and chlorinated pesticides. This book is a valuable resource for organic and agricultural chemists, as well as biologists, agriculturists, neurophysiologists, environmental scientists, and research workers.

    • Biotechnology of Blood

      • 1st Edition
      • June 28, 2014
      • Jack Goldstein
      • English
      • Paperback
        9 7 8 1 4 9 3 3 0 7 5 1 7
      • eBook
        9 7 8 1 4 8 3 2 9 4 4 6 9
      Biotechnology of Blood presents research on applications of biotechnology to blood and its components. The book is organized into four parts. Part I begins with an overview of the blood business in order to provide background of the industry, to identify problems, and perhaps some solutions that rely on the scientific advances made possible by biotechnology. This is followed by studies on the storage and preservation of red blood cells; autologous blood salvage procedures; the development procedures to provide a constant supply of blood group O; and the development of blood substitutes. Part II on plasma fractions includes studies on the preparation of plasma fractions, recombinant antihemophilic factors, and fibrinogen. Part III on the regulation of blood cell products includes studies such as hematopoietic stem cell processing and storage; and long-term bone marrow cell cultures. Part IV on blood-borne diseases examines the inactivation of viruses found with plasma proteins and viruses found with cellular components.

    • Cyclic Nucleotides and Protein Phosphorylation in Cell Regulation

      • 1st Edition
      • May 18, 2014
      • E.-G. Krause + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 2 7 2 9
      • eBook
        9 7 8 1 4 8 3 1 8 8 5 3 9
      Volume 54, Symposium S7: Cyclic Nucleotides and Protein Phosphorylation in Cell Regulation documents the proceedings of the 12th Federation of European Biochemical Societies (FEBS) Meeting held in Dresden, Germany on July 5-7, 1978. This book discusses the biological significance and biochemical aspects of cyclic nucleotides and protein phosphorylation in cell regulation. The general aspects of cyclic nucleotide metabolism and action; cyclic nucleotides and nervous system; and cyclic nucleotides in muscle tissues are also elaborated. This publication likewise covers the cyclic nucleotides in secretion processes and miscellaneous aspects of cyclic nucleotide-dependent and independent protein phosphorylation. This volume is valuable to biochemists and biologists concerned with the cyclic nucleotides and protein phosphorylation in cell regulation.

    • Rare Diseases and Orphan Drugs

      • 1st Edition
      • May 26, 2014
      • Jules J. Berman
      • English
      • Paperback
        9 7 8 0 1 2 8 1 0 2 7 6 3
      • Hardback
        9 7 8 0 1 2 4 1 9 9 8 8 0
      • eBook
        9 7 8 0 1 2 4 2 0 0 0 9 8
      Rare Diseases and Orphan Drugs shows that much of what we now know about common diseases has been achieved by studying rare diseases. It proposes that future advances in the prevention, diagnosis, and treatment of common diseases will come as a consequence of our accelerating progress in the field of rare diseases. Understanding the complex steps in the development of common diseases, such as cancer, cardiovascular disease, and metabolic diseases, has proven a difficult problem. Rare diseases, however, are often caused by aberrations of a single gene. In rare diseases, we may study how specific genetic defects can trigger a series of events that lead to the expression of a particular disease. Often, the disease process manifested in a certain rare disease is strikingly similar to the disease process observed in a common disease. This work ties the lessons learned about rare diseases to our understanding of common ones. Chapters covering the number of common diseases are minimized, while rare diseases are introduced as single diseases or as members of diseases classes. After reading this book, readers will appreciate how further research into the rare diseases may lead to new methods for preventing, diagnosing, and treating all diseases, rare or common.

    • The Peptides

      • 1st Edition
      • May 12, 2014
      • Eberhard Schröder + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 5 9 8 6 4
      The Peptides, Volume II: Synthesis, Occurrence, and Action of Biologically Active Polypeptides focuses on the synthesis of biologically active polypeptides and analogues. The publication first offers information on linear peptides and heterodetic cyclic peptides. Discussions focus on depsipeptides, polycyclic and monocyclic disulfides, naturally occurring biologically active peptides, glandular hormones, and tissue hormones. The text then ponders on homodetic cyclic peptides, including homodetic cyclic homomeric peptide antibiotics, polycyclic biologically active polypeptides, and homodetic cyclic heteromeric peptide antibiotics. The manuscript takes a look at the problems related with the synthesis of biologically active polypeptides, giving emphasis to a number of movements which elaborated on the matter and the advancements of preparative techniques and approaches leading to the purification of intermediates and end products. The publication is a valuable reference for researchers interested in the occurrence, synthesis, and action of biologically active polypeptides.

    • Methods in Virology

      • 1st Edition
      • June 28, 2014
      • Karl Maramorosch + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 3 1 9 1
      • eBook
        9 7 8 1 4 8 3 2 5 9 0 1 7
      Methods in Virology, Volume VIII focuses on the methods used in virology, including microscopy, hybridization, viruses, and fingerprint analysis. The selection first offers information on the hybridization of viral nucleic acids; applications of oligonucleotide fingerprinting to the identification of viruses; and immunosorbent electron microscopy in plant virus studies. Discussions focus on the detection of double-stranded RNA, principles and mechanisms of fingerprint analysis, preparation of labeled nucleic acid probes, and basic methods of nucleic acid hybridization. The text then elaborates on quantitative transmission electron microscopy for the determination of mass-molecular weight of viruses and use of thin sectioning for visualization and identification of plant viruses. Topics include technical procedures for processing plant tissues, cytological modifications of diagnostic value, procedure and treatment of data to obtain the average mass of virus particles, and applications in virology. The book takes a look at the detection of genome-linked proteins of plant and animal viruses; methods for assay, purification, and characterization of prions; and the use of mosquitoes to detect and propagate viruses. The selection is a valuable source of information for researchers interested in the methods employed in virology.

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