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    • Toxicological Aspects of Drug-Facilitated Crimes

      • 1st Edition
      • March 20, 2014
      • Pascal Kintz
      • English
      • Paperback
        9 7 8 0 1 2 4 1 6 7 4 8 3
      • eBook
        9 7 8 0 1 2 4 1 6 9 6 9 2
      Toxicological Aspects of Drug-Facilitated Crimes provides readers with an overview of the field of DFC: its history, toxicological effects, analysis, interpretation of results, the roles that age, gender and race may play, and clinical presentations of these drugs. The most commonly used drugs in DFC are addressed (alcohol, cannabis, MDMA, and cocaine), as well as an emerging range of pharmaceuticals (benzodiazepines, hypnotics, sedatives, neuroleptics, histamine H1-antagonists, or anesthetics), which are becoming more widely used, but are more difficult to detect. Edited by a world-renowned expert in the field of Forensic and Analytical Toxicology, Pascal Kintz, this book investigates toxicants of emerging concern and brings together a number of experts in the field to address the most recent discoveries on DFC toxicology.

    • Food Plant Safety

      • 1st Edition
      • March 11, 2014
      • Tatiana Koutchma
      • English
      • Paperback
        9 7 8 0 1 2 4 1 6 6 2 0 2
      • eBook
        9 7 8 0 1 2 4 1 6 6 6 7 7
      Food Plant Safety: UV Applications for Food and Non-Food Surfaces discusses the fundamental principles of ultraviolet (UV) light technology, and gives practical recommendations on UV processes and systems design for specific processing operations, as well as how microbial efficacy of UV light can improve the quality of existing product lines. Innovative research of ultraviolet light for food applications has been growing worldwide. With increased consumer demand for fresher, minimally processed but safe foods, comes the need for novel technologies to meet that demand. Ultraviolet technology has been taking its niche in food production as a non-chemical treatment to control and enhance safety of processing plants and storage facilities. This concise resource covers the fundamentals of this promising technology and its applications; it will benefit a broad audience of professionals in food engineering, processing, and product development, as well as graduate level students.

    • Analytical Applications of Immobilized Enzymes and Cells

      • 1st Edition
      • Volume 3
      • June 28, 2014
      • Lemuel B. Wingard + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 4 2 6
      • eBook
        9 7 8 1 4 8 3 2 1 5 8 5 3
      Analytical Applications of Immobilized Enzymes and Cells, Volume 3 presents a survey of the interdisciplinary interactions, developments, and trends on research in immobilized enzymes and cells. This volume is comprised of eight chapters. Chapters 1 to 4 are devoted to the description of methodologies and instrumentations which are used in routine analysis. Among those described are enzyme tubes, enzyme thermistors, and enzymic or microbial electrodes. Chapter 4 provides a theoretical analysis of electrode design. Subsequent chapters focus on solid-phase enzyme immunoassays and on techniques for in vivo monitoring of metabolites; economic evaluation of the use of high-purity enzymes in analysis; and an assessment of the significance of microprocessors and computer science in enzyme based analysis. Chemists and chemical engineers will find the book very useful.

    • Alcohol and Abnormal Protein Biosynthesis

      • 1st Edition
      • May 17, 2014
      • Marcus A. Rothschild + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 9 6 4 9
      • eBook
        9 7 8 1 4 8 3 1 5 2 0 6 6
      Alcohol and Abnormal Protein Biosynthesis: Biochemical and Clinical focuses on the methods for measuring protein metabolism and the effects of alcohol and altered protein intake as they affect the heart, liver, skeletal muscle, and the brain. Organized into six sections, this book begins with an overview on malnutrition and alcoholism, as well as available techniques for the study of protein synthesis. Subsequent section details the adaptation of protein synthesis and transport to alcohol and malnutrition. Section three discusses the skeletal and cardiac muscle protein metabolism. The last three sections describe the reaction of hepatic protein synthesis to malnutrition and alcohol; effects of alcohol on brain RNA metabolism; and alcohol associated cardiac and hepatic disease.

    • Predictive Modeling of Pharmaceutical Unit Operations

      • 1st Edition
      • April 9, 2014
      • Preetanshu Pandey + 1 more
      • English
      • Hardback
        9 7 8 0 0 8 1 0 0 1 5 4 7
      • eBook
        9 7 8 0 0 8 1 0 0 1 8 0 6
      The use of modeling and simulation tools is rapidly gaining prominence in the pharmaceutical industry covering a wide range of applications. This book focuses on modeling and simulation tools as they pertain to drug product manufacturing processes, although similar principles and tools may apply to many other areas. Modeling tools can improve fundamental process understanding and provide valuable insights into the manufacturing processes, which can result in significant process improvements and cost savings. With FDA mandating the use of Qualityby Design (QbD) principles during manufacturing, reliable modeling techniques can help to alleviate the costs associated with such efforts, and be used to create in silico formulation and process design space. This book is geared toward detailing modeling techniques that are utilized for the various unit operations during drug product manufacturing. By way of examples that include case studies, various modeling principles are explained for the nonexpert end users. A discussion on the role of modeling in quality risk management for manufacturing and application of modeling for continuous manufacturing and biologics is also included.

    • Toxicogenomics-Based Cellular Models

      • 1st Edition
      • January 2, 2014
      • Jos Kleinjans
      • English
      • Hardback
        9 7 8 0 1 2 3 9 7 8 6 2 2
      • eBook
        9 7 8 0 1 2 3 9 7 8 7 1 4
      Toxicogenomics-Based Cellular Models is a unique and valuable reference for all academic and professional researchers employing toxicogenomic methods with respect to animal testing for chemical safety. This resource offers cutting-edge information on the application of toxicogenomics to developing alternatives to current animal toxicity tests. By illustrating the development of toxicogenomics-based cellular models for critical endpoints of toxicity and providing real-world examples for validation and data analysis, this book provides an assessment of the current state of the field, as well as opportunities and challenges for the future. Written by renowned international toxicological experts, this book explores ‘omics technology for developing new assays for toxicity testing and safety assessment and provides the reader with a focused examination of alternative means to animal testing.

    • Fossil Fungi

      • 1st Edition
      • August 14, 2014
      • Thomas N Taylor + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 3 8 7 7 3 1 4
      • eBook
        9 7 8 0 1 2 3 8 7 7 5 4 3
      Fungi are ubiquitous in the world and responsible for driving the evolution and governing the sustainability of ecosystems now and in the past. Fossil Fungi is the first encyclopedic book devoted exclusively to fossil fungi and their activities through geologic time. The book begins with the historical context of research on fossil fungi (paleomycology), followed by how fungi are formed and studied as fossils, and their age. The next six chapters focus on the major lineages of fungi, arranging them in phylogenetic order and placing the fossils within a systematic framework. For each fossil the age and provenance are provided. Each chapter provides a detailed introduction to the living members of the group and a discussion of the fossils that are believed to belong in this group. The extensive bibliography (~ 2700 entries) includes papers on both extant and fossil fungi. Additional chapters include lichens, fungal spores, and the interactions of fungi with plants, animals, and the geosphere. The final chapter includes a discussion of fossil bacteria and other organisms that are fungal-like in appearance, and known from the fossil record. The book includes more than 475 illustrations, almost all in color, of fossil fungi, line drawings, and portraits of people, as well as a glossary of more than 700 mycological and paleontological terms that will be useful to both biologists and geoscientists.

    • Biochemical and Molecular Aspects of Selected Cancers

      • 1st Edition
      • May 10, 2014
      • Thomas G. Pretlow + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 4 9 6 9
      • eBook
        9 7 8 1 4 8 3 2 8 2 0 5 3
      Biochemical and Molecular Aspects of Selected Cancers, Volume I provides an overview of important topics and prototypes in cancer research. The book consists of papers provided by outstanding investigators in diverse disciplines in different areas of cancer research. This volume focuses on topics relevant to cancers in humans. It covers such topics as tumor-suppressor genes and human neoplasia; protein kinase C in neoplastic cells; and extracellular matrix interactions with tumor-progressing cells: tumor versus cell type-specific mechanisms. Structural and functional characteristics of human melanoma; steroid hormones and hormone receptors in neoplastic diseases; and patterns and significance of genetic changes in neuroblastomas are expounded as well. Oncologists, biochemists, cytologists, and other researchers in allied fields will find the book invaluable.

    • Primary Immunodeficiency Disorders

      • 1st Edition
      • August 26, 2014
      • Amos Etzioni + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 0 0 6 8 4
      • Hardback
        9 7 8 0 1 2 4 0 7 1 7 9 7
      • eBook
        9 7 8 0 1 2 4 1 1 5 5 4 5
      Primary Immunodeficiency Disorders: A Historic and Scientific Perspective provides a complete historical context that is crucial for students and researchers concerned with primary immunodeficiency. When researchers have a poor understanding of the way we arrived where we are in research, they can miss important points about a disease, or miss out on how to approach new diseases. This historical knowledge of research can assist greatly by showing how it was done in the past, demonstrating the successes and failures, so that it can be done better in the future. This book provides an understanding of the process going from clinical problem to lab and back to the clinic, based on historical experiences. Its chapters proceed from the discovery of the T and B cell lineages through the first BMT for immunodeficiency disorder; lab investigation and gene therapy for PID; the discovery of the gene for AT and its function; understanding cytokine defects; and many other stops along the way.

    • Food Security, Poverty and Nutrition Policy Analysis

      • 2nd Edition
      • February 13, 2014
      • Suresh Babu + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 0 0 6 6 0
      • Hardback
        9 7 8 0 1 2 4 0 5 8 6 4 4
      • eBook
        9 7 8 0 1 2 4 0 5 9 0 9 2
      Food insecurity, the lack of access at all times to the food needed for an active and healthy life, continues to be a growing problem as populations increase while the world economy struggles. Formulating effective policies for addressing these issues requires thorough understanding of the empirical data and application of appropriate measurement and analysis of that information. Food Security, Poverty and Nutrition Policy Analysis, Second Edition has been revised and updated to include hands-on examples and real-world case studies using the latest datasets, tools and methods. Providing a proven framework for developing applied policy analysis skills, this book is based on over 30 years of food and nutrition policy research at the International Food Policy Research Institute and has been used worldwide to impart the combined skills of statistical data analysis, computer literacy and their use in developing policy alternatives.This book provides core information in a format that provides not only the concept behind the method, but real-world applications giving the reader valuable, practical knowledge.

Related subjects

Agricultural and biological sciences

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Pharmacology

Toxicology