Books in Life sciences

Genes, Environment and Alzheimer's Disease

1st Edition
February 25, 2016
Orly Lazarov + 1 more
English
Hardback
9 7 8 0 1 2 8 0 2 8 5 1 3
eBook
9 7 8 0 1 2 8 0 2 8 8 5 8

Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline. It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of the disease. Evidence from experiments in rodent models of Alzheimer’s disease contributes major insight into the molecular mechanisms by which the environment plays its role in AD. Additionally, there are diseases related to lifestyle that may lead to AD. This volume reviews new discoveries related to all these factors, serving as a translational tool for clinicians and researchers interested in genetic and environmental risk factors for the disease.

Chemokines

1st Edition
Volume 570
February 24, 2016
Tracy Handel
English
Hardback
9 7 8 0 1 2 8 0 2 1 7 1 2
eBook
9 7 8 0 1 2 8 0 2 1 9 5 8

Chemokines, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in chemokines, and includes sections on such topics as chemokine detection using receptors, tracking cellular responses to chemokines, recognition of GAG-bound chemokines, and the production of chemokine receptor complexes for structural and biophysical studies.

Epi-Informatics

1st Edition
February 24, 2016
Jose Medina-Franco
English
Paperback
9 7 8 0 1 2 8 0 2 8 0 8 7
eBook
9 7 8 0 1 2 8 0 2 8 0 9 4

Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes features multidisciplinary strategies with strong computational approaches that have led to the successful discovery and/or optimization of compounds that act as modulators of epigenetic targets. This book is intended for all those using or wanting to learn more about computational methodologies in epigenetic drug discovery, including molecular modelers, informaticians, pharmaceutical scientists, and medicinal chemists. With a better understanding of different molecular modeling and cheminformatic approaches, readers can incorporate these techniques into their own drug discovery projects that may involve chemical synthesis and medium- or high-throughput screening. In addition, this book highlights the significance of epigenetic targets to the public health for molecular modelers and chemoinformatians. The goal of this reference is to stimulate ongoing multidisciplinary research and to further improve current computational methodologies and workflows in order to accelerate the discovery and development of epi-drugs and epi-probes.

Tumor Immunology

1st Edition
Volume 130
February 24, 2016
Robert Schreiber
English
Hardback
9 7 8 0 1 2 8 0 5 1 5 6 6
eBook
9 7 8 0 1 2 8 0 9 6 5 5 0

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. This volume focuses on tumor immunology.

The Diverse Faces of Bacillus Cereus

1st Edition
February 23, 2016
Vincenzo Savini
English
Hardback
9 7 8 0 1 2 8 0 1 4 7 4 5
eBook
9 7 8 0 1 2 8 0 1 6 9 3 0

The Diverse Faces of Bacillus cereus elucidates all characteristics of this microorganism, from its environmental and ecologic relevance, to its veterinary involvement, its clinical settings, most common B. cereus associated food poisoning episodes, and the newest airway disease pictures mimicking the inhalation of anthrax. Due to its environmental distribution, B. cereus may cause serious, even fatal human diseases. The organism shows many diverse faces, as it is not only a veterinary pathogen, but also used as a biocontrol agent to control vegetable decay due to its natural antimicrobial properties. Once considered as a mere colonizer or contaminant, Bacillus cereus is nowadays acquiring increasing importance as an agent of nosocomial infections. The book's target audience is familiar with this opportunistic pathogen and will benefit from this clear compendium on the classical and molecular techniques and procedures that may be adopted or followed to correctly identify this intriguing multi-faceted microorganism.

Pharmacological Mechanisms and the Modulation of Pain

1st Edition
Volume 75
February 23, 2016
James E Barrett
English
Hardback
9 7 8 0 1 2 8 0 3 8 8 3 3
eBook
9 7 8 0 1 2 8 0 3 9 3 2 8

Pharmacological Mechanisms and the Modulation of Pain, the newest volume in the Advances in Pharmacology series, presents the pharmacological mechanisms and the modulation of pain. With a variety of chapters and the best authors in the field, this volume is an essential resource for pharmacologists, immunologists, and biochemists alike.

Nanotechnology Tools for the Study of RNA

1st Edition
Volume 139
February 23, 2016
Satoko Yoshizawa
English
Hardback
9 7 8 0 1 2 8 0 4 5 6 5 7
eBook
9 7 8 0 1 2 8 0 4 5 7 4 9

This volume of Progress in Molecular Biology and Translational Science introduces emerging strategies of studying RNA structure and function using nanotechnological tools. The volume aims to provide the readers with a novel view and give them opportunities to think about how to incorporate the new technologies into their own research.

Ion Channels as Therapeutic Targets, Part A

1st Edition
Volume 103
February 23, 2016
Rossen Donev
English
Hardback
9 7 8 0 1 2 8 0 4 7 9 4 1
eBook
9 7 8 0 1 2 8 0 5 2 1 0 5

Ion Channels as Therapeutic Targets is the latest volume in the popular Advances in Protein Chemistry and Structural Biology series, an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

Advances in Genetics

1st Edition
Volume 93
February 23, 2016
Theodore Friedmann + 2 more
English
Hardback
9 7 8 0 1 2 8 0 4 8 0 1 6
eBook
9 7 8 0 1 2 8 0 5 2 1 7 4

Advances in Genetics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions.

Advances in Applied Microbiology

1st Edition
Volume 94
February 23, 2016
Geoffrey Michael Gadd + 1 more
English
Hardback
9 7 8 0 1 2 8 0 4 8 0 3 0
eBook
9 7 8 0 1 2 8 0 5 2 1 9 8

Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology. The series contains comprehensive reviews of the most current research in applied microbiology, and includes recent research on the roles of fungal communities in soil nutrient recycling, the microbial nitrogen cycle in soil, and the inter-kingdom associations between soil bacteria, fungi, and mycorrhizal fungi.

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