Skip to main content
Elsevier

Books in Life sciences

  • Behavioral Biometrics and Artificial Intelligence for Neurodegenerative Diseases Assessment

    • 1st Edition
    • Vincenzo Dentamaro + 2 more
    • English
    Behavioral Biometrics and Artificial Intelligence for Neurodegenerative Diseases Assessment explores cutting-edge, non-invasive techniques for the early detection of neurodegenerative diseases. The book focuses on behavioral biometrics, which analyzes patterns in a person’s actions rather than directly measurable traits. By utilizing artificial intelligence methods—like machine learning and deep neural networks—it enables the observation of subtle changes in gait, handwriting, and speech. These advanced approaches offer promise for earlier and more accurate diagnosis, potentially improving outcomes for millions affected by conditions such as Alzheimer’s and Parkinson’s diseases through timely intervention and personalized care.In addition to its core coverage, the book delves into the practical applications of wearable sensors and the use of everyday devices like smartphones and tablets in assessments. It provides comprehensive chapters on how these technologies can aid clinicians and researchers in monitoring disease progression outside traditional clinical settings.

  • Innovative Nanotechnology: Transforming Skin Cancer Diagnosis and Treatment

    • 1st Edition
    • Volume 169
    • English
    Innovative Nanotechnology: Transforming Skin Cancer Diagnosis and Treatment, Volume 169 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include an Introduction to Nanotechnology in Dermatology, Basics of Skin Cancer: Types, Diagnosis, and Current Challenges, Current Challenges in Skin Cancer Diagnosis and Treatment, Nanocarriers for Drug Delivery in Skin Cancer, Nanotechnology in Skin Cancer Diagnosis, Therapeutic Nanoparticles and Targeted Therapy, and much more.Additional chapters cover Nanotechnology in Photodynamic and Photothermal Therapy for Skin Cancer, Challenges in Translating Nanotechnology from Research to Clinical Practice, Nanotechnology and Immunotherapy Synergies in Skin Cancer, Patient-Centric Approaches and Personalized Nanomedicine in Skin Cancer, The Role of Theranostics and Nanotheranostics in Skin Cancer Management, Preclinical and Clinical Trials in Nanotech Skin Cancer Treatment, Safety, Ethical, and Regulatory Considerations in Nanotechnology for Skin Cancer, and many more interesting chapters on topics of current interest.

  • The Microbiome and Cancer Treatment

    Overcoming Resistance and Enhancing Efficacy
    • 1st Edition
    • Sadhna Aggarwal + 3 more
    • English
    The Microbiome and Cancer Treatment: Overcoming Resistance and Enhancing Efficacy delves into the intricate relationship between the microbiome and cancer treatment, highlighting the microbiome's critical role in drug resistance and therapeutic efficacy. The book's chapters are meticulously organized to provide a deep understanding of how the microbiome interacts with the immune system and influences cancer development and response to therapies. This book opens new avenues for investigation by providing a better understanding of the mechanisms of resistance and the role of microbiome alterations in chemoresistance.Sect... also address the complex "chicken-or-egg" relationship between microbiome alterations and chemoresistance. A diverse blend of chapters foster interdisciplinary collaboration across fields such as immunology, microbiology, oncology, and pharmacology, promoting holistic approaches to cancer treatment. Readers will benefit by gaining awareness and a better understanding of how the microbiome impacts health, particularly in the context of cancer, leading to more informed health choices.

  • The Roadmap of Research

    A Guide to Understanding and Writing a Medical Study
    • 1st Edition
    • Vincenzo Giordano + 3 more
    • English
    The Roadmap of Research: A Guide to Understanding and Writing a Medical Study helps readers easily grasp the context, methodologies, findings, and implications of research studies, build on previous work, avoid redundancies, and identify areas where new studies can contribute significantly. The book enables researchers to innovate, propose new ideas, and design studies that contribute novel perspectives or methodologies to the field. Each step in this roadmap plays a pivotal role in the research process, from building a foundation of knowledge through reading and understanding, to generating new ideas through critical thinking, and finally, disseminating findings through clear and effective writing.

  • Protein-Based Nanoparticles in Drug Delivery

    • 1st Edition
    • Prashant Kesharwani
    • English
    Protein-based Nanoparticles in Drug Delivery is a comprehensive book aimed at pharmaceutical scientists and researchers both in academia and corporate environments focused on nanotechnology drug delivery and pharmaceutical-relat... disciplines. The book covers the design and characterization of various protein nanoparticles, sheds light on the power of an endogenous substance as a drug delivery system, and highlights the possible future trends in the use of protein-based drug delivery. It covers in-depth novel applications of protein-based drug delivery from fundamental to most current use cases. The book comprises three parts. Part one is devoted to the foundations of protein-based drug delivery, including nanocarriers development, drug encapsulation, targetability, and in vivo properties. Part two explores the applications of protein-based nanoparticles in drug delivery, covering topics such as protein nanoparticles in cancer therapy, genetic material delivery, and nanocarriers based on milk protein, silk, and gliadin. Part three addresses recent advances and regulatory aspects of protein-based nanoparticles in drug delivery, including clinical translation, challenges, biological toxicity, and environmental hazards associated with protein-based nanoparticles. Protein-based Nanoparticles in Drug Delivery provides a complete journey of protein-based drug delivery, offers an in-depth understanding of the design and characterization of various protein nanoparticles, and highlights possible future trends in this field. Pharmaceutical scientists will benefit from the novel applications of protein-based nanoparticles drug delivery approaches in the biological field. Nanotechnologists, biologists, chemists, physicists, engineers, and clinicians will also benefit from the foundational content provided as a basis to support communication and tackle the multidisciplinary challenges associated with research in this exciting field.

  • Histone Deacetylases in Neurodegenerative Disease Part B

    • 1st Edition
    • Volume 734
    • English
    Histone Deacetylases in Neurodegenerative Disease, Part B, Volume 734 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics surrounding the Interaction of HDAC6 ZnF UBP with Tau affects its stability by NMR and Simulation studies, Protocols for In Vitro Analysis of Liquid-Liquid Phase Separation of Proteins, Histone deacetylases in NS, Histone Deacetylase 6 ZnF UBP domain enhances podosome formation in neuronal cells studied by high-resolution confocal microscopy, Methodological approach to Investigate Peroxiredoxin 1 Deacetylation by Histone Deacetylase 6, Critical structural features of HDAC11 inhibitors, and much more.Additional chapters in this release include Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration, Elucidation of Site-Specific Ubiquitination on Chaperones in Response to Mutant Huntingtin, Protein acetylation dynamics (histone and non-histone) and role protein deacetylases in disease, Epigenetic Clues: Predicting Maternal Depression Through DNA Methylation, A short guide on in vivo transfection of flag-HDAC4 in dentate gyrus for study of adult neurogenesis in brain trauma, Decoding the Acetylation Journey from Neural Crest to Melanocyte, and more.

  • Chromatin Signaling and Diseases

    • 2nd Edition
    • Olivier Binda + 2 more
    • English
    Chromatin Signaling and Diseases, Second Edition, a volume in the Translational Epigenetics series, covers the molecular mechanisms that regulate gene expression, which governs embryonic development, growth, and human pathologies associated with aging, such as cancer. Although human genome sequencing continues to improve, molecular mechanisms regulating gene expression remain largely misunderstood. The impact of gene expression defects associated with malfunctioning chromatin signaling are considered in this update. In addition, this new edition has addresses developments in the field, from phase separation of membrane-less organelles and local segregation of factors to chromatinization of naked foreign DNA and cancer evolution as regulated by chromatin signaling.Chromatin signaling proposes that small protein domains recognize chemical modifications on the genome scaffolding histone proteins, facilitating the nucleation of enzymatic complexes at specific loci that then open up or shut down the access to genetic information, thereby regulating gene expression. The addition and removal of chemical modifications on histones, as well as the proteins that specifically recognize these are also considered.

  • Autophagy – Part B

    • 1st Edition
    • Volume 404
    • English
    Autophagy Part B provides an in-depth exploration of advanced mechanisms, functions, and roles of autophagy in health and disease. This volume features contributions from leading experts, covering recent developments in autophagy research, its implications in cellular homeostasis, neurodegeneration, cancer, immunity, and therapeutic strategies. Designed for researchers, clinicians, and students, the book offers valuable insights into the complexities and applications of autophagy in modern biomedical science.

  • Microbiome in Head and Neck Cancer: Pathogenesis, Diagnosis and Therapeutic Implications

    • 1st Edition
    • Volume 169
    • English
    Microbiome in Head and Neck Cancer: Pathogenesis, Diagnosis and Therapeutic Implications, Volume 169 in the Advances in Immunology series, presents an authoritative exploration on how microbial communities contribute to the initiation, progression, and treatment of head and neck cancers. Chapters highlight The Microbiome of the Head and Neck Region, Overview Head and Neck Microbiota and the Factors Influencing the Head and Neck Microbiome, Mechanistic Pathways of Dysbiosis in Cancer Development, Oral Microbiota and OPMDs, Oral Potentially Malignant Disorders (OPMDs): An Overview, Oral Microbiota and Oral Cancer, Oral Squamous Cell Carcinoma (OSCC): An Overview, and much more.Additional chapters cover the Role of the Oral Microbiome in Oral Cancer (OSCC), Microbiome as a Prognostic Indicator in Oral Cancer, Diagnostic and Therapeutic Applications, Microbiome-Based Diagnostic Approaches, Modulating the Head and Neck Microbiome for Cancer Prevention, Microbiome-Targeted Therapeutics in Head and Neck Cancer, Artificial Intelligence in Microbiome Data Analysis: Applications in Head and Neck Cancer, and Challenges and Future Directions in Head & Neck Microbiome Research.

  • Brain Energy Metabolism in Alzheimers Disease - Part C

    • 1st Edition
    • Volume 188
    • English
    Brain Energy Metabolism in Alzheimer’s Disease – Part C, Volume 188 in the International Review of Neurobiology series, presents the latest research on metabolic dysfunction and its role in neurodegenerative diseases. This volume brings together contributions from an international panel of experts, exploring the molecular, cellular, and systemic aspects of energy metabolism in Alzheimer’s disease and related disorders.Chapters in this release examine metabolic therapeutic targets in Alzheimer’s disease, alterations in brain energy metabolism in comparison with Parkinson’s disease, and the role of epigenetic modulation through natural compounds. Additional sections address mitochondrial dysfunction, disruption of metabolic pathways, and the contribution of glial cells to neurodegenerative processes.Further contributions explore metabolic disorders linked to Parkinson’s disease, signaling pathways in neurodegeneration, and advances in therapeutic and diagnostic strategies targeting key enzymes. The volume also highlights the role of intestinal microbiota, nanocarrier-based therapeutic approaches, and emerging treatments such as HDAC inhibitors. Together, these chapters provide a comprehensive overview of the mechanisms, biomarkers, and therapeutic prospects related to energy metabolism in neurodegenerative diseases, making this volume an essential reference for researchers and clinicians in neuroscience and neurobiology.

Related subjects