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Elsevier

Books in Life sciences

  • A Quick Reference to Obstetric Anesthesia

    • 1st Edition
    • Adithya Devadas Bhat + 1 more
    • English
    A Quick Reference to Obstetric Anesthesia is a comprehensive resource on the latest in anesthetic care for the pregnant patients. It covers the newest evidence on various critical topics in obstetric anesthesia, and the inclusion of recommended perioperative protocols provides definitive references for optimal care. This book serves as an “in the moment” tool for solving challenging clinical problems, while functioning as a reference for both experienced clinicians and trainees. It also includes relevant patient management protocols, as well as numerous emerging topics that are lacking in presently available texts.A Quick Reference to Obstetric Anesthesia is meant for anyone seeking immediately accessible information to facilitate real-time care of pregnant patients. Its approachable yet comprehensive knowledge base will be appreciated by anesthesia professionals at every level.

  • A Comprehensive Guide for the Novice Researcher in Clinical Trials

    • 1st Edition
    • Miltiadis Lytras + 2 more
    • English
    A Comprehensive Guide for Novice Researcher in Clinical Trials is a must-have resource for individuals embarking on the journey of clinical research. This book is tailored for beginners, offering a clear and structured introduction to the vital principles, methodologies, and skills required to design and conduct robust clinical trials. Spanning 13 chapters, it meticulously covers the entire clinical trial process, emphasizing Good Clinical Practice (GCP) standards. From foundational research concepts to advanced trial strategies, the guide empowers readers to confidently navigate the complexities of clinical trials and contribute meaningfully to the field of healthcare.In addition to its foundational content, the book addresses a variety of important topics, such as ethical considerations, regulatory compliance, and the development of trial protocols. It explores different trial designs, types of bias, and the historical evolution of clinical research. Practical sections on data management, monitoring, statistical analysis, and project management offer readers hands-on guidance for real-world application. Notably, the book includes a dedicated focus on regulatory affairs in Saudi Arabia, making it particularly valuable for health professionals in that region.

  • Arginase: Structure, Function, and Therapeutic Targeting

    • 1st Edition
    • Volume 740
    • English
    This volume of Methods in Enzymology, entitled “Arginase: Structure, Function, and Therapeutic Targeting,” provides a comprehensive, methodology-driven perspective on arginase research spanning molecular, biochemical, and translational domains.The volume is organized into four sections that reflect the breadth of the field, spanning structural and mechanistic enzymology, inhibitor design and therapeutic development, clinical and metabolic aspects of arginine biology, and the evolutionary and functional diversity of arginase and related enzymes. Chapters cover experimental approaches to enzyme expression, purification, and structural characterization; synthetic and computational strategies for inhibitor discovery; and emerging therapeutic modalities, including antibody-based targeting of specific arginase isoforms, advanced delivery systems, and engineered enzyme formulations.Importa... the volume extends beyond classical views of arginase as an enzyme of arginine metabolism, highlighting its broader structural and functional context within the ureohydrolase superfamily and related guanidinohydrolase enzymes, including alternative substrates, catalytic diversity, and roles in microorganisms and plants. These perspectives emphasize arginase function in nitrogen metabolism, host–pathogen interactions, and environmental and physiological adaptation.By integrating contributions from both academia and industry, this volume emphasizes reproducible methodologies and provides a cohesive “from enzyme to organism” framework, connecting fundamental structure–function relationships with applications in metabolism, vascular biology, and therapeutic development.

  • Cholinergic Drugs for Alzheimer's Disease

    From Central Cholinergic Neurotransmission to Drug Therapies and Natural Products with Multitarget Actions
    • 1st Edition
    • Cheorl-Ho Kim
    • English
    Cholinergic Drugs for Alzheimer’s Disease: From Central Cholinergic Neurotransmission to Drug Therapies and Natural Products with Multitarget Actions addresses the urgent need for advanced resources in neuropharmacology. The first section presents mechanistic insights into cholinergic drugs, current hypotheses for Alzheimer’s Disease progression, neurotransmitter systems, receptor biology, and the evolution of acetylcholinesterase inhibitors, including hybrid and multi-target drugs. It also covers clinical status, neuromuscular blockers, non-adrenergic neurotransmitters, protein kinase inhibitors, inflammation modulation, NMDA antagonism, biomarkers, and AI-assisted drug discovery.The second section explores natural alkaloidal and non-alkaloidal compounds, molecular docking, SAR analysis, and daily consumable resources, with the third section investigating marine-derived AChE inhibitors, dual- and multi-target drug concepts, and emerging therapeutic compounds. This book equips the scientific community with a robust foundation for understanding and innovating in Alzheimer’s Disease therapy. By integrating molecular biology, pharmacology, and computational approaches, it empowers researchers and clinicians to address treatment challenges, optimize drug design, and leverage natural products for multifactorial intervention.

  • Biofabrication and Synthetic Biology in Medicinal Plants

    Advances in Biotechnology and Breeding
    • 1st Edition
    • Eti Sharma + 2 more
    • English
    Biofabrication and Synthetic Biology in Medicinal Plants: Advances in Biotechnology and Breeding presents recent technological advances for enhancing medicinal plants as sources of plant-based biopharmaceuticals. It covers biofabrication, synthetic biology, modern biotechnological tools, and innovative breeding strategies tailored for medicinal plant improvement. While these technologies are well established in crop plants, their application in medicinal plants remains underexplored. Medicinal plants are rich sources of therapeutic compounds traditionally used across cultures to treat a wide range of diseases and health conditions. These plants produce diverse bioactive molecules, including terpenoids, flavonoids, alkaloids, and phenolics, many of which exhibit significant pharmacological potential. For centuries, medicinal and aromatic plants have played a vital role in human healthcare and continue to be valued globally. Recent advances in synthetic biology, metabolic engineering, and biotechnology promise to enhance the production, quality, and efficacy of these bioactive compounds, addressing unmet medical needs and contributing to sustainable healthcare. This book compiles insights from leading experts, offering a comprehensive reference for researchers, early-career scientists, students, and professionals working in medicinal plant biotechnology and breeding.

  • Encyclopedia of Cardiovascular Research and Medicine

    • 2nd Edition
    • Vasan Ramachandran S. + 1 more
    • English
    Now in its second edition, the Encyclopedia of Cardiovascular Research and Medicine is a four‑volume print and online reference that brings together the essential knowledge needed to understand the heart and vascular system. Designed for students, clinicians, researchers, and instructors, it offers clear, authoritative coverage of how the cardiovascular system develops, functions, becomes injured, and can be repaired. Because cardiovascular disease remains the world’s leading cause of death, this edition provides the up‑to‑date scientific and clinical insights needed to support research, inform care, and improve outcomes.This revised edition includes around 180 expert articles spanning cardiac development and regeneration, vascular biology, genetics and omics technologies, coronary and acute cardiac syndromes, heart failure, electrophysiology and device therapies, imaging, population health, and modern research methods. By spanning basic, clinical, and population sciences, the encyclopedia supports a wide range of users from those seeking introductory knowledge to specialists pursuing advanced expertise in cardiovascular medicine.

  • Lo esencial en farmacología. Cursos Crash

    • 6th Edition
    • Catrin Page
    • Spanish
    Con una fórmula que ha demostrado su éxito a lo largo de los últimos 25 años, cada volumen de la serie se ha actualizado por completo para facilitar el estudio. La serie está escrita por estudiantes de últimos cursos y recién graduados que acaban de superar sus exámenes, y toda la información ha sido cuidadosamente revisada por profesores universitarios. Este volumen de la serie se ha mejorado para satisfacer las necesidades de los estudiantes de Medicina actuales, y las de los estudiantes y profesionales de otras disciplinas sanitarias que requieran un acceso rápido a los aspectos esenciales de la farmacología. Cada capítulo guía de forma sucinta por todos los temas curriculares, integrando los aspectos clínicos con la ciencia básica relevante y evitando los detalles innecesarios o confusos. Los cuadros destacados a lo largo del texto ofrecen los apuntes, las sugerencias y los puntos clave esenciales. Se incluye una sección de autoevaluación totalmente revisada y adaptada a los últimos formatos de exámenes para comprobar los conocimientos y para ayudar en la preparación de las pruebas. Completamente revisada y actualizada, esta sexta edición ofrece un recurso accesible de aprendizaje y repaso que facilite la compresión de los principios y las aplicaciones de la farmacología en todas las áreas de la medicina y la cirugía. Comienza con un capítulo introductorio sobre los principios básicos de la farmacología. En el resto de los capítulos, se describen los efectos de los fármacos en los distintos sistemas orgánicos y se incluyen actualizaciones sobre los avances farmacológicos más recientes en medicina (p. ej., las nuevas terapias dirigidas en oncología y enfermedades inflamatorias, así como los nuevos tratamientos utilizados en el manejo de la diabetes y la insuficiencia cardíaca). La sección de autoevaluación se ha actualizado para reflejar el contenido y el estilo de varios exámenes de pre- y posgrado. Las preguntas de autoevaluación se centran en la farmacología clínica y su aplicación a casos reales de la práctica clínica.

  • Stem Cell-Mediated Regulation of Pyroptosis

    • 1st Edition
    • Debalina Bhattacharya + 1 more
    • English
    Stem Cell-Mediated Regulation of Pyroptosis investigates the role of pyroptosis in various types of stem cells and stem cell-derived exosomes, considering how they can accelerate tissue repair and regeneration in inflammatory diseases. The book begins with an introduction to the mechanisms of pyroptosis and methods available for its detection. It then considers pyroptosis and its relationship to stem cells before delving into the interaction across various conditions, ranging from cerebral injury, spinal injury, cardiac injury, osteoarthritis, cancer, and more. Users will find the latest research and future directions in the study of stem cells and pyroptosis, thus enabling further understanding of the cellular mechanisms underlying this form of cell death and the clinical significance of stem cells in the context of pyroptosis-induced diseases. Therapeutic implications and potential strategies targeting this pathway for the treatment of such conditions are also considered, providing a comprehensive reference that will be useful to researchers working across cell biology, regenerative medicine, immunology, therapeutics, and other related fields.

  • Técnicas en histología y biología celular

    • 3rd Edition
    • Luis Montuenga Badía + 2 more
    • Spanish
    Esta nueva edición de Técnicas en histología y biología celular, completamente actualizada, desarrolla de modo asequible los fundamentos teóricos y metodológicos de las técnicas más relevantes en histología y biología celular, incluyendo aquellas técnicas de biología molecular relacionadas con ambas disciplinas. Presenta los fundamentos de las diversas metodologías a estudiantes del ámbito de las ciencias biológicas, la bioquímica y la biomedicina, así como a técnicos de anatomía patológica y otros profesionales biosanitarios que deseen conocer estas técnicas con un abordaje avanzado. Asimismo, proporciona a los investigadores, técnicos o clínicos que se inician en el campo del laboratorio o la investigación biológica y biomédica la información necesaria para introducirse con seguridad en el ámbito del análisis microscópico y la biología celular, incluidas sus bases moleculares. Incluye capítulos sobre procesamiento y tinción de las muestras; inmunolocalización; hibridación in situ de ácidos nucleicos; cultivo de tejidos; técnicas multiómicas; microscopía confocal, electrónica y de fuerza atómica; análisis de imagen; ingeniería tisular, etc. Así mismo, la nueva edición presenta numerosas imágenes originales y esquemas que ilustran los conceptos básicos y muestran ejemplos prácticos del uso de las diversas técnicas. Ofrece acceso a la versión digital del libro a travésde https://online.vital... con nuevos recursos didácticos asociados a cada uno de los temas, incluyendo actividades y casos prácticos, preguntas de autoevaluación, imágenes complementarias, bibliografía adicional y enlaces de interés.

  • Understanding the Functional, Flavor, and Nutritional Properties of Blue Foods

    • 1st Edition
    • Volume 119
    • English
    Understanding the Functional, Flavor, and Nutritional Properties of Blue Foods, Volume 119 provides a holistic and in-depth examination of blue foods, moving beyond basic nutrition to explore their multifaceted roles. Chapters in this new release include Red seaweed Palmaria palmata: A sustainable protein source for the future, Nutritional and Functional Bioactive Compounds in Fish, Fermented fish: A Deep Dive into Tradition, Innovation, ad Health Benefits, Phlorotannins from marine algae, Shrimp: Nutrition, Preservation and Processing, Nutritional , Flavor and Functional Properties of Golden Pomfret, Fish by-products: Functional properties, health attributes, and challenges, and much more.Additional chapters cover Exploring the Flavor Profiles of Blue Foods: Mechanistic Insights, Factor Analysis, and Assessment Strategies, and Non-thermal processing of fish: Evolution of flavor, physico-chemical properties, and bioactivities. By integrating perspectives from food science, nutrition, gastronomy, and sustainability, this volume positions blue foods as essential components of future food systems, offering scientific insights for their valorization and innovative application.

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