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Books in Life sciences

  • Nanotechnology Applications for the Diagnosis and Therapeutic Treatment of Fungal Diseases

    • 1st Edition
    • Virendra Gajbhiye + 2 more
    • English
    Nanotechnology Applications for the Diagnosis and Therapeutic Treatment of Fungal Diseases offers comprehensive coverage of the fundamentals of fungal diseases and the applications of nanotechnology for their diagnosis and treatment.The book covers the basics of human fungal pathogens, the molecular mechanisms of infection, and current diagnostic strategies and treatment regimes. It then goes on to discuss nanotechnology-based approaches for the detection and identification of human fungal pathogens. It also discusses antifungal drugs, their modes of action, and how nanoparticles are utilized to deliver these agents, highlighting their significance in treating various fungal infections. Additionally, it provides a comprehensive overview of nanotechnology-based products, as well as the current and future applications of nano-methodologies and technologies in the field of fungal infectious diseases. With contributions from experts in the field, Nanotechnology Applications for the Diagnosis and Therapeutic Treatment of Fungal Diseases is an informative resource for scientists, researchers, and medical personnel to better understand fungal diseases in order to design and develop novel and accessible nano-based therapies for their treatment.

  • Antimicrobial Resistance in Humans, Animals, and the Environment

    One Health Approach
    • 1st Edition
    • Kunal Ranjan + 3 more
    • English
    Antimicrobial Resistance in Humans, Animals, and the Environment: One Health Approach examines the global impact of antimicrobial resistance (AMR) with a specific focus on the interconnectedness between animal, human, and environmental health. The book details the origin, evolution and ecology of AMR and its updated epidemiology. It discusses the transmission of antimicrobial resistance between humans, animals, and the environment. It delves into the molecular mechanisms of drug resistance development and epidemiology in human and animal health; the different challenges in treating antimicrobial-resist... infections including rapid diagnosis and the development of new antimicrobial agents; and alternative strategies treating drug-resistant infections. Antimicrobial Resistance in Humans, Animals, and the Environment: One Health Approach is a useful comprehensive resource for researchers, academics postgraduate students, PhD students, early career researchers, and medical scientists in microbiology, infectious diseases, and biotechnology, public health professionals, clinical personnel treating AMR, or policymakers interested in implementing antimicrobial stewardship program in hospitals.

  • Microbial Enzymes

    Classification, Biochemistry, Production and Applications
    • 1st Edition
    • Abdel Moneim Elhadi Sulieman
    • English
    Microbial Enzymes: Classification, Biochemistry, Production and Applications explores the multifaceted roles of microbial enzymes, emphasizing their stability, ease of handling, and manipulation, all of which make them invaluable in various industrial processes. With 25 in-depth chapters, the book delves into the biochemistry of enzymes, their various sources, and their importance in biotechnology. It covers modern techniques for microbial enzyme detection and determination, methods of enzyme immobilization, and the application of microbial enzymes in industries such as food, medicine, pharmaceuticals, and textiles. Special sections discuss the biosynthesis of metal nanoparticles by microbial enzymes and the role of microbial toxins in different sectors. The book's chapters are organized in a way that provides detailed insights into the classification of enzymes, the mechanisms of microbial enzymes, and their industrial importance. Topics include bacterial, fungal, and algal enzymes, their applications, and the latest advancements in enzyme technology. Other sections address the challenge of antibiotic resistance and explores innovative methods for enzyme production and molecular engineering.

  • Proteomics in Cell Communication

    • 1st Edition
    • Volume 200
    • English
    Proteomics in Cell Communication, offers a comprehensive exploration of the dynamic field of proteomics and its vital role in understanding cellular communication. This book includes interesting chapters on topics such as In vivo cell-type specific secretome profiling, Assays for surface antigens in extracellular vesicles using proximity labeling strategy, Cell type-specific proximity biotinylation using TurboID to identify secreted proteins from cardiomyocytes in vitro and in vivo, Native-state and cell type-specific proteomics using TurboID proximity labeling in mouse models, Adapted Luminex approach to assess phosphoproteins and cytokines released from specific cell types in the brain in vivo, and much more.Other sections covers In-depth cell-selective proteomics and secretomics in vivo based on azidonorleucine labelling, Visualizing and profiling de novo protein synthesis in Drosophila with cell-type specificity, A Split GFP Approach for Cell-Type-Specific Protein Localization Analysis in Drosophila, Quantitative deep profiling of the cell surface proteome using the "Cell Surface Capture" technique, Proteomic profiling of extracellular fluids to identify secreted proteins from muscle and fat tissues, and much more.

  • Plant-Based Proteins Processing

    Emerging Trends and Applications
    • 1st Edition
    • C.K. Sunil + 2 more
    • English
    Plant-Based Proteins Processing: Emerging Trends and Applications covers sources, extraction, properties, bioavailability, modification, applications, and marketing opportunities, in addition to the conventional and emerging technologies applied for obtaining plant-based proteins. This book consists of five sections, starting with Section A which includes chapters on overview, sources, digestibility and bioavailability, nutritional properties, and food byproducts as a source of protein. Section B covers the extraction of plant-based proteins, which has chapters on the chemical, enzyme, and novel techniques for extraction of plant proteins. Section C chapters focus on the modification of the plant protein, including all the modification methods (Thermal, Non-thermal, Biological, and Chemical methods) and their effects on the protein. Section D includes the applications of the proteins, and the last Section, E, covers the market, challenges, and future opportunities for plant-based proteins. Plant-Based Proteins Processing is a complete guide for students, researchers, professionals, consumers, food manufacturers, and others who are engaged in plant-based protein production.

  • Methods for the Study of Microbial Biofilms

    Current Trends and Recent Advancements
    • 1st Edition
    • Abhishek Guldhe + 2 more
    • English
    Methods for the study of microbial biofilms: Current Trends and Recent Advancements provides a detailed overview of the latest techniques for the study of biofilms. The book explores a wide range of methods for the characterization and study of cells within biofilms, including microscopy techniques, genomic approaches, transcriptomics, proteomic and proteogenomic tools. Computational and mathematical modelling are also covered.Chapters investigate the physiology of biofilm cells, gene expression pathways related to the formation, maturation and dispersion of biofilms, and molecular factors governing the biofilm formation and development, providing an overview of techniques that can be used at the cellular and molecular level. This book provides a broad overview of the biofilm field, along with the range of techniques that can be used to study and better understand them.

  • Protein Misfolding Diseases

    • 1st Edition
    • Volume 148
    • English
    Protein Misfolding Diseases, delves into the intricate molecular mechanisms behind a class of devastating disorders caused by abnormal protein folding. This comprehensive book explores interesting and updated topics, including Protein misfolding in hemophilia, Characterizing Protein Misfolding: Inside and Out, Heat Shock proteins (HSPs) as chaperones for Oncogenesis, Protein Misfolding and Cancer: Molecular Insights and Future Perspectives, Proteostasis and Pathogenesis: Unraveling the Complexity of Protein Misfolding Disorders, Small molecule inhibitors targeting α-synuclein aggregation: Progress and future outlook, and much more.Additional sections cover Chaperone Machinery in Neurodegeneration: A Spotlight on Protein Misfolding Diseases and Calpain- mediated proteolytic cleavage.

  • Chemoresistance in Glioblastoma

    Understanding and Management
    • 1st Edition
    • Dileep Kumar + 1 more
    • English
    Chemoresistance in Glioblastoma: Understanding and Management gives clear insights into the detailed characteristic aspects of glioblastoma disease and the different therapeutic targets that are employed in reducing resistance to chemotherapeutic agents. The book delves deep into the root causes of multidrug resistance and the quest for novel molecular targets among growth factors, receptors, signal transduction proteins, microRNAs, transcription factors, proto-oncogenes, and tumor suppressor genes. In addition, it gives insights on the pathological and molecular features of glioblastoma and the role of cancer stem cells in the resistance to chemo and immunotherapy.While designed as a comprehensive guide, the book also serves as a valuable reference for professionals seeking to deepen their understanding, refine their skills, and explore new avenues within chemoresistance.

  • Precision Medicine in Neurodegenerative Diseases: From Research to Clinical Practice

    • 1st Edition
    • Volume 297
    • English
    Precision Medicine in Neurodegenerative Diseases: From Research to Clinical Practice, Volume 298 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics such as Introduction to Precision Medicine in Neurodegeneration, Genetic and Epigenetic Drivers of Neurodegenerative Disorders, Biomarkers: From Early Detection to Treatment Personalization, Multi-Omics Integration in Disease Research, AI and Emerging Technologies for Diagnosis, Advanced Neuroimaging in Precision Neurology, and much more.Additional chapters cover Precision Therapeutics for Alzheimer's Diseases, Personalized Management of Parkinson's Diseases, Pharmacogenomics and CRISPR-Based Therapies, Patient-Centric Care and Digital Health Tools, and Global Case Studies and Collaborative Frameworks, Future Horizons: Innovation, Aging, and Equity.

  • Neurobiology of Aging

    Exploring Cognitive Decline and Neurodegeneration
    • 1st Edition
    • Sachchida Nand Rai
    • English
    Neurobiology of Aging: Exploring Cognitive Decline and Neurodegeneration is a comprehensive reference exploring the complexities of the aging brain. This book examines the intricate processes driving cognitive decline and neurodegeneration. From the gradual loss of neurons and synapses to the formation of protein aggregates characteristic of Alzheimer's disease, each chapter reviews key aspects of brain aging. Chapters dissect the mechanisms driving neuronal loss, synaptic dysfunction, and protein misfolding, shedding light on the intricate interplay of oxidative stress, inflammation, and mitochondrial dysfunction. This book also navigates through strategies for healthy brain aging, from the impact of diet and exercise to the role of cognitive stimulation.

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