Books in Life sciences

Medicinal Plant Research in Africa

2nd Edition
April 16, 2025
Victor Kuete
English
eBook
9 7 8 0 4 4 3 3 0 1 7 1 1

Medicinal Plant Research in Africa, second edition is an updated and complete reference on the pharmacology of most relevant African species and their phytochemical properties. Although pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes, however there was no global standard book on the nature and specificity of chemicals isolated in African medicinal plants. This book has set the standard when it first published in 2013 and now is updated with novel phytochemicals belonging to diverse classes of terpenoids, phenolics, and alkaloids. The first chapter cover monoterpenes and related phytochemicals and is followed by sesquiterpenes on chapter two. Chapter tri reviews diterpenoids and chapter four provides an overview of triterpenes and steroids. Essential oils, simple phenols, phenolic acids and related esters come next in chapters five and six, respectively. The following chapters cover coumarins, flavonoids, quinones, xanthones, lignans and stilbenes. Tannins, alkaloids, and ceramides. Chapters 15 to 20 focus on specific health conditions starting with antibiotic infection, antimalarial and other antiprotozoal diseases, cytotoxic and anticancer activity, anti-inflammatory and analgesic action, antidiabetic botanicals and the applications of African plant phytochemicals on reproductive, cardiovascular, and central nervous systems conditions. The final chapter covers the market and industry updates since the first edition published. "Medicinal Plant Research in Africa, 2 Ed." provides a complete overview of the main phytochemical principles present in the African flora and their pharmaceutical use. Pharmaceutical scientists, Ethnopharmacists, botanists, and medicinal chemists will benefit from the content organization and the inclusion of the most recent methods for structural identification of phytochemicals, pharmacological techniques, and data interpretation.

Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies

1st Edition
Volume 291
April 16, 2025
Nasrollah Moradikor + 1 more
English
Hardback
9 7 8 0 4 4 3 3 4 4 2 5 1
eBook
9 7 8 0 4 4 3 3 4 4 2 6 8

Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies is a comprehensive exploration of how stress affects the brain at a molecular level and its broader implications for mental and neurological health. The book delves into the mechanisms by which stress triggers changes in brain function, including the activation of the hypothalamic-pituita... (HPA) axis, synaptic plasticity alterations, oxidative stress, neuroinflammation, and mitochondrial dysfunction. It examines how these molecular processes contribute to conditions such as neurodegeneration, anxiety, depression, and other stress-related disorders. Furthermore, the book provides an in-depth analysis of current therapeutic interventions, both pharmacological and behavioral, as well as natural antidotes that aim to mitigate the adverse effects of stress on the brain. By synthesizing evidence from cutting-edge research, this book offers valuable insights for scientists, clinicians, and mental health professionals seeking to understand and address the complex interplay between stress and brain health.

Tumor-Targeting with Stimuli-Responsive Vesicular Nanocarriers

1st Edition
April 15, 2025
Ankit Jain + 2 more
English
Paperback
9 7 8 0 4 4 3 2 9 1 2 5 8
eBook
9 7 8 0 4 4 3 2 9 1 2 6 5

Tumour-Targeting with Stimuli Responsive Vesicular Nanocarriers: Basics to Emerging Applications not only acquaints scientists and science interns with the fundamental knowledge of the experimental aspects and state-of-the-art technology for vesicular carriers to equip their rational application in tumor targeting, but also provides a holistic understanding of regulatory concerns, patents, and clinical trials. In 15 chapters. this book provides basics and advances in stimuli-responsive vesicular carriers for tumor targeting based on findings outlined in highly organized tables, illustrative figures, and flow charts.With a focus on the extrapolation of bioengineering tools in the domain of vesicular carriers, stimuli-responsive features concerning tumors, drug delivery approaches, and associated challenges, it helps readers to define the major gaps in knowledge that can lead to significant scientific discoveries in therapy, diagnosis, and theragnosis of cancer.

The Potential of Cancer Biomarkers

1st Edition
April 14, 2025
Pranav Kumar Prabhakar
English
eBook
9 7 8 0 4 4 3 2 9 2 8 0 4

The Potential of Biomarkers: From Discovery to Clinical Application addresses the challenges related to knowledge dissemination, interdisciplinary understanding, diagnostic complexity, quality assurance, patient care, research advancement, education, and professional development within the field of clinical biochemistry. The book provides a holistic solution by offering comprehensive insights and practical guidance to a diverse audience, contributing to the enhancement of healthcare and biomedical research. Each chapter explores the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more.Cancer biomarkers, the molecular signatures of cancer, hold immense promise in revolutionizing how we diagnose, treat, and personalize therapies for cancer patients. In this curated reference, esteemed contributors explore the multifaceted landscape of biomarker research, offering a wealth of insights and expertise in genomics, proteomics, metabolomics, and more.

Terrestrial Biomes

1st Edition
April 12, 2025
Germano Leão Demolin-Leite
English
Hardback
9 7 8 0 4 4 3 3 6 5 6 9 0
eBook
9 7 8 0 4 4 3 3 6 5 7 0 6

Terrestrial Biomes: Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity explores the effects of anthropogenic activities on Earth’s terrestrial biomes, species, and climate. The book summarizes operational and potential monitoring tools to conserve or recover terrestrial biomes at a global scale. Written by international experts in ecology and biodiversity conservation, this book identifies the challenges and threats to terrestrial organisms and connects them to real cases of conservation.This is an important resource for students, professors, researchers, and governmental and non-governmental organizations active in biodiversity conservation and climate change mitigation.

The Science of the Brain

1st Edition
April 11, 2025
Ari Rappoport
English
Paperback
9 7 8 0 4 4 3 4 5 0 0 8 2
eBook
9 7 8 0 4 4 3 4 5 0 0 9 9

The Science of the Brain: Function, Dysfunction and Disease is an innovative exploration into the complex interplay between brain functionality and various neurological disorders, meticulously compiled by a world-renowned researcher. This groundbreaking book presents a comprehensive analysis, offering the first complete theories for eleven major brain disorders, including Alzheimer’s, schizophrenia, and autism spectrum disorder, among others. Each chapter delves into a unique theoretical framework, from lipid raft theories to sympathetic nervous system impacts, all while proposing potential treatment targets grounded in established scientific data. In addition to two chapters that lay the groundwork for understanding brain adaptability and anatomy, other chapters independently dissect each disorder, revealing fresh insights that promise to invigorate research and clinical application. This essential resource not only serves neuroscientists and clinicians seeking a deeper understanding of brain disorders but also invites entrepreneurs interested in novel therapeutic avenues. With its rich references and pioneering theories, this book is poised to become indispensable to students, researchers and clinicians, paving the way for future discoveries in brain health and disease management.

Imaging of Neurofluids, An Issue of Neuroimaging Clinics of North America

1st Edition
Volume 35-2
April 10, 2025
Nivedita Agarwal + 1 more
English

In this issue of Neuroimaging Clinics, guest editors Drs. Nivedita Agarwal and Anja van der Kolk bring their considerable expertise to the topic of Imaging of Neurofluids. Top experts discuss key topics in this burgeoning field to create a primer ideal for neuroradiologists and radiologists. Topics include the basics of neurofluids, animal models, gadolinium-based imaging, perfusion-based imaging, diffusion tensor imaging, PET imaging, and specific articles on perivascular spaces, parasagittal dura mater and meningeal lymphatics, amyloid-related imaging abnormalities, and Alzheimer’s disease.

Emerging Fuzzy Intelligent Systems for Smart Healthcare Management

1st Edition
April 10, 2025
Shahzaib Ashraf + 3 more
English
eBook
9 7 8 0 4 4 3 3 3 9 9 8 1

Emerging Fuzzy Intelligent Systems for Smart Healthcare Management: Applications of Disc q-Rung Orthopair Fuzzy Sets presents comprehensive methodological frameworks and the latest empirical research findings concerning disc q-rung orthopair fuzzy operators, with a specific focus on their applications in smart technologies for healthcare management. The book solves a crucial problem by offering readers an invaluable opportunity to conduct a comparative analysis, contrasting the proposed methods with their existing knowledge base. Disc q-Rung Orthopair sets, being the generalization of q-Rung Orthopair fuzzy sets, which are, in turn, the generalization of Pythagorean fuzzy sets, extend the capabilities of handling uncertainty beyond conventional fuzzy sets.The authors strive to narrow the knowledge gap by clarifying the practical applications of disc q-rung orthopair fuzzy logic. In addition, it explores an enhanced version of q-Rung Orthopair Fuzzy Sets, specifically focusing on Disc q-Rung Orthopair Fuzzy Sets, introducing various types of operators. These operators play a crucial role in solving decision-making and optimization problems. A notable contribution is the development of a hybrid operator, termed as the Disc q-Rung Orthopair Fuzzy Hybrid Weighted Averaging/Geometric (D-qROFHWA/G) operator.

Adenoviral Vectors for Gene Therapy

3rd Edition
April 9, 2025
David T. Curiel + 1 more
English
Hardback
9 7 8 0 3 2 3 8 9 8 2 1 8
eBook
9 7 8 0 3 2 3 9 5 8 1 4 1

Adenoviral Vectors for Gene Therapy, Third Edition, provides detailed, comprehensive coverage of gene delivery vehicles based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, as platforms for gene therapy and gene editing, as well as for oncology approaches, making them class leading agents in the gene-advanced therapies arena.The fully updated and expanded third edition covers the basic biology of adenoviruses and highlights the potential use of adenoviral vectors for the treatment of disease, including their construction, propagation, and purification, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models. The book also considers the regulatory issues surrounding human clinical gene therapy trials. New chapters include adenoviral vaccines for veterinary applications, adenoviruses for gene editing, nonhuman primate adenoviruses, COVID-19 vaccines, vaccine applications, and oncolytic adenoviruses for antitumor immunization. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors.

Innovative Conservation Techniques and Perspectives

1st Edition
April 8, 2025
Germano Leão Demolin-Leite
English
Hardback
9 7 8 0 4 4 3 4 0 4 9 0 0
eBook
9 7 8 0 4 4 3 4 0 4 9 1 7

Innovative Conservation Techniques and Perspectives: Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity explores operational and potential monitoring tools to conserve and/or recover biomes at a global scale. Written by international experts in ecology and biodiversity conservation, this book identifies operational, emerging, and proposed methods for land monitoring and management across the world’s biomes. This important resource on biodiversity is an ideal resource for students, professors, researchers, and both governmental and non-governmental organizations active in biodiversity conservation.

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