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Books in Life sciences

  • Innovative Targeting Strategies in Breast Cancer Therapy

    • 1st Edition
    • Pankaj Kumar Singh + 4 more
    • English
    Innovative Targeting Strategies in Breast Cancer Therapy is a comprehensive reference addressing the challenge of non-specific drug distribution in the body, along with severe toxicity and adverse effects, by offering insights into targeted breast cancer treatment. It further educates researchers on formulating and developing novel carriers with target-specific attributes (such as targeted liposomes, nanoparticles, micelles, and dendrimers), contributing to a more refined approach to breast cancer. This book's content is presented in 12 chapters. The first chapters introduces the reader to the different breast cancer therapies followed by indepth information on targeting . Recognizing the need for targeted drug delivery in breast cancer treatment, this book presents an encompassing compilation of advanced research and formulation strategies. By focusing on effectively targeting cancer cells, the book mitigates dose-related toxicity associated with cytotoxic drugs, providing a comprehensive resource for improved treatment approaches. Research in oncology, pharmacology, medical researchers, biomedical engineers and clinical professionals will find this an essential reference.
  • The Science of Pharmacology

    • 1st Edition
    • Jahangir Moini + 3 more
    • English
    The Science of Pharmacology offers a detailed and contemporary exploration of medications, delving into the scientific principles behind drug actions and their therapeutic applications. It is an essential resource for students in pharmacology and pharmaceutical sciences, providing foundational knowledge on a wide range of topics. The book addresses the effects of drugs on various bodily systems, such as the nervous, respiratory, and cardiovascular systems, and also covers their impact on mental health and behavior. Beyond the core topics, the book also discusses special subjects like herbal medications and drug interactions.It includes valuable teaching materials, including test banks and quizzes, and offers comprehensive insights into toxicological treatments, making it an invaluable tool for both learning and teaching in the field.
  • Sommeil et santé mentale

    Troubles du sommeil et des rythmes biologiques associés aux troubles psychiatriques
    • 1st Edition
    • Pierre-Alexis GEOFFROY
    • French
    Les monographies en Psychiatrie sont des ouvrages de référence sur les troubles psychiatriques et les grandes problématiques de la discipline. Ellespermettent aux praticiens d’approfondir et d’actualiser leurs connaissances, en exposant les données fondamentales actuelles et leurs applications dansla pratique clinique. Le sommeil, pilier essentiel de la santé mentale, reste encore trop souvent sous-estimé dans la pratique psychiatrique. Pourtant, ces troubles sont omniprésents et intimement liés à de nombreux troubles psychiatriques, qu’il s’agisse des troubles de l’humeur, anxieux, psychotiques, neurodéveloppementau... des addictions ou encore des troubles des conduites alimentaires. Le véritable enjeu réside aujourd’hui dans la compréhension fine des mécanismes physiologiques et neurobiologiques du sommeil, afin d’améliorer le diagnostic, la prise en charge et la prévention des troubles psychiatriques associés. Les récentes avancées enneurosciences, en génétique et en chronobiologie offrent des perspectives inédites : il devient crucial d’intégrer pleinement la dimension du sommeil au cœur de la psychiatrie moderne, pour proposer des soins plus précis et personnalisés.Premie... ouvrage de référence en langue française sur le sujet, il offre une exploration complète des liens entre le sommeil, les rythmes biologiques et la santé mentale, structurée en trois parties essentielles. La première partie pose les bases fondamentales et cliniques du sommeil et de ses troubles en psychiatrie, en abordant différents champs : l’histoire, la physiologie, la neurobiologie, la clinique, l’épidémiologie, la psychométrie, ainsi que l’organisation du systèmede soins. La seconde partie se concentre sur les altérations du sommeil associées aux différents troubles psychiatriques, allant de l’enfant au sujet âgé. Elle propose également une sémiologie clinique éclairée par les dernières données scientifiques et des recommandations d’experts, des stratégies de diagnostic et des outils innovants. Enfin, une troisième partie traitent des prises en charge de ces troubles du sommeil et des rythmes biologiques en psychiatrie, avec des approches thérapeutiques variées et détaillées, allant de la pharmacothérapie aux psychothérapies et aux chronothérapeutiques... ouvrage est un outil indispensable aux psychiatres, psychologues, médecins d’autres spécialités impliqués dans la médecine du sommeil, chercheurs, étudiants, ainsi qu’à tous ceux qui souhaitent approfondir leurs connaissances et leur pratique, dans ce domaine en pleine expansion. Cet ouvrage s’adresse à un large public professionnel. À la croisée de la psychiatrie, de la psychologie, de la physiologie, des neurosciences et de la médecine du sommeil, Sommeil et santé mentale a pour ambition d’offrir des repères solides et des outils pratiques pour mieux comprendre, diagnostiquer et traiter les troubles du sommeil en psychiatrie. POINTS CLÉSComprendre les mécanismes physiologiques, neurobiologiques et chronobiologiques du sommeil en lien avec la santé mentale.Repérer les troubles du sommeil associés aux principales pathologies psychiatriques et leur impact sur le diagnostic et la prise en charge.Proposer une stratégie thérapeutique adaptée au trouble et au patient.Pierre Alexis Geoffroy, est professeur des universités à l’université Paris Cité et praticien hospitalier au sein du département de psychiatrie et addictologie de l’hôpital Bichat-Claude Bernard et du 22e secteur du GHU Paris psychiatrie et neurosciences. Il est également chef de service ducentre de référence ChronoS (psychiatrie, chronobiologie et sommeil).
  • Secondary Metabolites in Stress and Disease Management

    A Natural Alternative
    • 1st Edition
    • Amrita Srivastava + 1 more
    • English
    Secondary Metabolites in Stress and Disease Management: A Natural Alternative details the sources and diversity of microbial and plant secondary metabolites, the methods used for their detection and extraction, their novel applications in disease management, and inclusion in mainstream therapy. Organized into three main sections, the book begins by discussing the potential of microbes, plants, microalgae, and cyanobacteria as valuable sources of secondary metabolites, their role and mechanisms of action in symbiotic and competitive interactions, extractions and purification strategies, and the means to maximize their production. The book goes on to explore the utility of secondary metabolites in mitigating plant stress and their therapeutic impact on human health management. With contributions from experts in the field, Secondary Metabolites in Stress and Disease Management is a useful interdisciplinary resource for researchers, professors, graduate and postgraduate students, and industry professionals studying applied microbiology, biotechnology, biochemistry, pharmacology, and plant science.
  • Artificial Intelligence-Driven Precision Medicine for Triple Negative Breast Cancer

    Innovations and Insights in TNBC Management
    • 1st Edition
    • Sachin Namdeo Kothawade + 1 more
    • English
    Artificial Intelligence-Driven Precision Medicine for Triple-Negative Breast Cancer: Innovations and Insights in TNBC Management is a groundbreaking exploration into the transformative role of artificial intelligence in revolutionizing the management of triple-negative breast cancer (TNBC). In 19 chapters, this comprehensive guide navigates the intersection of cutting-edge technology and healthcare, offering insights that bridge the gap among medical professionals, researchers, and individuals affected by TNBC. Diving into the complexities of TNBC, this book unveils the potential of artificial intelligence (AI) in enhancing diagnostic accuracy, personalizing treatment strategies, and reshaping the landscape of breast cancer care. From radiomics and genomic data analysis to predictive modeling and patient engagement, each chapter unveils the latest innovations and provides the practical applications of AI to empower healthcare practitioners and improve patient outcomes. This book is a timely and valuable resource for health professionals, scientists and researchers, students, and all those who wish to broaden their knowledge in the allied field.
  • Aerophytic Algae and Cyanobacteria

    Diversity, Ecology, and Biogeography
    • 1st Edition
    • Saúl Blanco
    • English
    Aerophytic Algae and Cyanobacteria: Diversity, Ecology, and Biogeography expands our understanding of microalgae and cyanobacteria that colonize air-exposed substrates. These species, often overlooked in marine and freshwater studies, play crucial roles in various ecosystems. Introductory chapters cover their morphology, physiological adaptations, and biogeography, highlighting their ecological significance and interactions within ecosystems. Other sections addresses future research directions, applications in environmental assessments, conservation, water and air quality management, bioremediation, and pollution control. The book, authored by a global team of phycologists, also explores taxa such as edaphic and corticolous diatoms, aeroplanktonic protists, and phototrophic phytotelmata.
  • Heart Failure in the Child and Young Adult

    From Bench to Bedside
    • 2nd Edition
    • Joseph Rossano + 5 more
    • English
    Heart Failure in the Child and Young Adult: From Bench to Bedside, Second Edition highlights unique aspects of heart failure in the young. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure and then progresses through diagnosis, management, treatment, and surgery, finally concluding with advanced special topics, including genetics, self-management, and nanomedicine.This new edition covers advancements in the field, including additional chapters and discussion on biomarkers, neuromuscular disease, quality of life, palliative care, and the impact of COVID-19 in myocarditis and multisystem inflammatory syndrome in children. It will serve as an indispensable reference to basic science researchers in cardiology, pediatrics, cardiologists, and pediatric cardiologists.
  • Machine Learning in Drug Development: Part 1

    • 1st Edition
    • Volume 64
    • English
    Machine Learning in Drug Development: Part One, Volume 64 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field. Chapters in this release include Artificial Intelligence in Small Molecule and Nucleic Acid Research: A Review, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, AI-aided Drug Development for Protein Degraders: Biology Validation, Disease-association, Drug Repurposing, Transforming Modern Drug Discovery with Machine Learning, Artificial Intelligence in the Development of Antiviral Drugs: Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery.
  • Myasthenia Gravis, Part B

    • 1st Edition
    • Volume 183
    • English
    Myasthenia Gravis, Part B, Volume 183 in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Typical and Atypical Clinical Presentations, Diagnosis and Differential Diagnosis, Clinical Evaluation, Myasthenia Gravis in Women, Fatigue and Myasthenia Gravis, Clinical and Electrophysiologic Outcomes, Standard Treatment and Different Geographical Approaches, Rescue Treatments, Novel Treatments for Myasthenia Gravis, Measuring Treatment-Related Side Effect Burden in Myasthenia Gravis, Exercise and Myasthenia Gravis, The Social and Personal Impact of Myasthenia Gravis, and Future Perspectives.
  • Interaction of Food Macromolecules

    The Matrix of Future Foods
    • 1st Edition
    • Ibrahim Khalifa + 2 more
    • English
    Interaction of Food Macromolecules: The Matrix of Future Foods provides a detailed understanding on why biological macromolecules, i.e., proteins, lipids, and carbohydrates with ligands interactions are essential to understanding biology at the molecular level. The book aims to create a multidisciplinary forum of discussion on the interaction between macromolecules and ligands, providing an understanding on how biological macromolecules with ligands interactions are central to facilitating the discovery, design, and development of future, functional foods. In addition, it outlines information available on the macromolecules-ligan... interaction that happens inside the food matrixes and inside our bodies.Knowing about the mechanisms responsible for the macromolecules-ligan... recognition and binding facilitates the discovery, design, and development of future and functional foods.