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Elsevier

Books in Life sciences

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 65
    • English
    Progress in Medicinal Chemistry brings together state-of-the-art reviews and critical insights from leading scientists in the field. Each volume surveys the latest advances in drug discovery and development, with a focus on practical strategies, novel modalities, and real-world case studies. From target identification and structure-based design to optimization of pharmacokinetic properties, safety assessment, and translational science, these volumes provide a comprehensive, up-to-date overview for researchers, graduate students, and professionals working in medicinal chemistry, pharmacology, and related life sciences.

  • Current Approaches to Cryo-electron Microscopy

    • 1st Edition
    • Volume 223
    • English
    Cryo-electron microscopy (cryo-EM) has emerged as a transformative technique in structural biology, driving an exponential increase in the number of structures deposited in the Protein Data Bank. Current workflows now routinely achieve the near-atomic resolution essential for understanding the molecular pathology of neurodegenerative and metabolic disorders. This provides a comprehensive overview of the field, tracing the evolution from early structural studies to modern pipelines powered by deep-learning algorithms for helical reconstruction. We address the persistent bottleneck of sample preparation, detailing the physical challenges of fibril clumping and interfacial adsorption, alongside emerging solutions to these problems. Furthermore, we examine the complexities of structural polymorphism, discussing how environmental factors and seeding drive conformational diversity and how this heterogeneity impacts biochemical assays. Finally, we highlight the translational value of these high-resolution maps, demonstrating how they enable the rational, structure-based design of peptide inhibitors and small molecules capable of disaggregating pathogenic fibrils.

  • Lights on for the Nervous System: Exploring the Effects of Photobiomodulation - Part A

    • 1st Edition
    • Volume 189
    • English
    Lights on for the Nervous System: Exploring the Effects of Photobiomodulation: Part A, Volume 187 in the International Review of Neurobiology series, highlights new advances in understanding how light interacts with the human body and brain. This comprehensive volume presents chapters written by an international board of authors, covering the history and theory of therapeutic light use, the underlying mechanisms of light–cell interactions, and the systemic effects of light exposure. It explores cognitive enhancement, sleep regulation, and microbiome modulation, as well as the potential of light-based interventions for neurodegenerative disorders, chronic pain, traumatic brain injury, depression, and retinal diseases.Specific sections cover History of Humans Using Light, Theory of Light: Why Should It Work, Mechanisms of Light, Systemic Effects of Light, Light Application and Dosage, How Does Light Affect Brain Activity, Light Talks: The Role of Biophoton in Cellular Communication, Biophotons: Communication with Light, Light Effects on Brain Activity: Simulations/Dynamic Function, Cognitive Enhancement through Transcranial Infrared Laser Stimulation: Insights from Research, Light Effects on the Microbiome, Lights On for Sleep, Exploring the Effect of Red and Near Infrared Light on Neurodegenerative Disease, Light Effects on Parkinson's Disease: Intracranial Application, Light Effects on Parkinson's Disease: Transcranial Application, and much more.

  • Advances in Agronomy

    • 1st Edition
    • Volume 198
    • English
    Advances in Agronomy, Volume 198, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Autophagy – Part C

    • 1st Edition
    • Volume 406
    • English
    Autophagy trilogy, Part C dives into the mature landscape of cellular housekeeping, weaving together the mechanistic precision of modern biology with the larger questions of health, aging, and resilience. Building on the foundations laid in Parts A and B, this book takes the reader from the microscopic machinery inside a single cell to the sweeping implications for organisms, ecosystems, and medicine.

  • Natural extracellular vesicles: a new nanomedicine for cancer

    • 1st Edition
    • KN ArulJothi + 5 more
    • English
    "Natural-Derived Extracellular Vesicles: Innovations in Nanomedicine" explores the potential of natural-derived extracellular vesicles (NDEVs) as next-generation tools in therapeutic applications. Shifting the focus from mammalian-derived EVs, this book highlights plant, fungal, bacterial, and algal sources, promoting a sustainable and biocompatible approach to drug delivery and disease modulation. The content emphasizes the unique properties of NDEVs in cancer therapy, immunomodulation, and regenerative medicine, addressing the limitations of conventional therapies by enhancing drug bioavailability and reducing off-target effects. It also provides insights into underexplored sources and practical guidance on safety, scalability, and regulatory considerations. For the academic audience, this book serves as a comprehensive resource that bridges nanotechnology and biomedical sciences. It equips researchers, clinicians, and pharmaceutical scientists with consolidated knowledge and experimental techniques, empowering them to explore the evolving frontiers of precision-driven therapeutics rooted in nature.

  • Cellular Communication in Mammalian Germ-line Development

    • 1st Edition
    • Volume 169
    • English
    Cellular Communication in Development, Volume 169 provides a comprehensive overview of the intricate signaling pathways and molecular mechanisms that govern how cells communicate during the development of multicellular organisms. This volume explores the essential roles of cell-to-cell communication in processes such as embryogenesis, tissue patterning, organ formation, and differentiation. Specific chapters include Specification of pgcs, Establishing and maintaining gonadal cell fate, Role of retinoic acid in meiosis, Assembly of primordial follicles, Activation of primordial follicles, Mechanisms of germ-soma communication during follicular growth, Somatic regulation of oocyte meiotic arrest and resumption, Ovarian stroma/function/role in aging, and much more.Additional sections explore New approaches to supporting follicle growth/ovarian function in vitro, Cancer therapy - effects on survival/development of oocyte/follicle, Female germ cells from somatic cells, Spermatogenic stem cell niche, Role of macrophages in testis function, Male germ cells from somatic cells, and more.

  • Advances in Parasitology

    • 1st Edition
    • Volume 131
    • English
    This book explores the intersection of molecular biology, genomics, and ecology to redefine our understanding of parasitic organisms and their management. Beginning with the application of -omics research in platyhelminth parasites of fish, demonstrating how genomic and proteomic data are essential for understanding host-parasite dynamics and developing novel vaccines and treatments to support sustainable aquaculture. The focus then shifts to the complex internal ecosystems of parasites, and examining how their associated microbiomes—comprisi... bacteria, fungi, and viruses—influence parasite fitness, virulence, and host interactions. Finally, the book highlights the genus Entamoeba, delving into how how next-generation and long-read sequencing technologies have revolutionized the identification of cryptic species and improved epidemiological surveillance for pathogens like E. histolytica. Together, these chapters provide a modern framework for parasitology through the lens of advanced genetic tools and ecological integration.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 88
    • English
    Advances in Microbial Physiology, Volume 88 explores the latest research and developments in microbial physiology, providing a comprehensive overview on how microorganisms function, adapt, and interact with their environments. This volume brings together leading experts to discuss fundamental processes such as metabolism, growth, gene regulation, signal transduction, stress responses, and cellular differentiation in bacteria, archaea, and fungi. Chapters cover Steroids as Antibacterials, From Feeding Cell to Fruiting Body: Multidrug Transport in the Life cycle of Dictyostelium discoideum, Evolution of xenobiotic catabolism, Glycyl-radical enzymes, How anaerobes cope with oxygen, and Extracellular Electron Transfer: From Early Life to Modern Biogeochemistry and Applications.

  • Public Participation and Ethics Communication in Brain Research, Innovation, and Health

    • 1st Edition
    • Volume 9
    • English
    Public Engagement and Ethical Communication in Brain Research, Innovation, and Health, Volume Nine in the Developments in Neuroethics and Bioethics series, provides a comprehensive overview of various understandings of neuroscience and (neuro)ethics communication across research, policy, and society. Specific chapters in this new release include Neurohype Across Borders: How Media Narratives Shape Public Perception of Neurotechnology in English- and Spanish-Speaking Countries, Physicians’ Resistance Towards Pandemic Public Health Policies in Romania: Navigating Misinformation, Ethical Challenges, and Responsibility in Science Communication, Foresight Scenarios as Communicative Instruments in Anticipatory Neuroethics, and much more.Additional chapters include Draw closer to me: Participatory visual storytelling to include socio-cultural perspectives in neuroethics and policymaking, Against the Narrative of the Insufficiency of Human Rights on the Neurorights Discourse, Reflective accounts from collaborative neuro-oncology research: perspectives from patient partners and researchers, Responsible conceptualization in research and innovation, Anticipating Polarization: Public Discourse and the Unpreparedness of Neuroethics Communication, Shared Responsibility for Communicating Neuroscience Research: A Case Study for Spinal Cord Injury, and much more.Featured topics include creative and participatory approaches to (neuro)ethics communication, the impact of narratives on public perception and science policy, the importance of responsible communication in neuroscience, and the dynamics between patient partners and researchers. The volume also addresses cross-cultural perspectives and focuses on comparative case studies of current emerging neuroscience research and neurotechnologies across countries.

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