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Elsevier

Books in Life sciences

  • Mucosal Barriers and Host-Microbiota Interplay

    Dysbiosis to Barrier Dysfunction
    • 1st Edition
    • Linda Chia-Hui Yu
    • English
    Mucosal Barriers and Host-Microbiota Interplay: Dysbiosis to Barrier Dysfunction, a volume in Elsevier's new series Hot Topics in Physiology, provides an in-depth exploration of mucosal barriers, including their structure, establishment, and consideration of different diseases and intervention strategies. Published in association with the International Union of Physiological Sciences (IUSP), this is an ideal reference for those researching or studying biology and medicine, particularly gastroenterology. Biotechnological companies working on metagenomics sequencing and analysis may also find this volume useful.As a massive load of commensal microbes, consisting of bacteria, viruses, and fungi resides in the gastrointestinal tract and other mucosal surfaces, collectively termed microbiota, this book provides an update on new and existing knowledge. Mucosal barriers, including the epithelial layers and immune cells act as the frontline to strategically confine these microorganisms and prevent the entry of microbes into the body proper.

  • Emerging Diagnostic Glucose Sensing Approaches

    Diabetes
    • 1st Edition
    • Abhishek Kandwal + 2 more
    • English
    Emerging Diagnostic Glucose Sensing Approaches surveys past and recent work on non-invasive blood glucose monitoring. The book highlights two complementary paths: electromagnetic-wave... sensing, using physical models and advanced sensors to measure glucose non-invasively; and physiological techniques (ECG/EEG) integrated with artificial intelligence and deep learning to infer glucose levels. It discusses how physical models, biomedical methodologies, and engineering prototyping enable accurate analysis and device development. With a focus on breakthroughs in electromagnetic sensors and non-invasive research, this volume serves as a foundational reference for biomedical researchers and engineers pursuing next-generation glucose monitoring.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 65
    • English
    Progress in Medicinal Chemistry brings together state-of-the-art reviews and critical insights from leading scientists in the field. Each volume surveys the latest advances in drug discovery and development, with a focus on practical strategies, novel modalities, and real-world case studies. From target identification and structure-based design to optimization of pharmacokinetic properties, safety assessment, and translational science, these volumes provide a comprehensive, up-to-date overview for researchers, graduate students, and professionals working in medicinal chemistry, pharmacology, and related life sciences.

  • Smart Healthcare 2.0

    Integrating Digital Twins with AI-Driven Predictive Analytics
    • 1st Edition
    • Ramesh Chandra Poonia + 1 more
    • English
    Smart Healthcare 2.0: Integrating Digital Twins with AI-Driven Predictive Analytics offers a groundbreaking exploration of how digital twin technology, combined with real-time sensing and predictive analytics, is transforming healthcare delivery. As the global healthcare landscape shifts toward proactive, personalized care, this book addresses the urgent need for comprehensive resources that unify artificial intelligence, Internet of Things (IoT), and biomedical engineering within the digital twin framework. It provides an essential guide for researchers, engineers, and clinicians aiming to harness virtual patient models and data-driven insights to improve health outcomes and system efficiency in the era of ubiquitous healthcare.This volume covers a wide spectrum of topics, starting with foundational concepts of digital twins in precision health and advancing through smart sensing technologies, scalable system architectures, and AI-powered predictive analytics. Readers will explore detailed discussions on edge-cloud computing, secure communication protocols including blockchain, and simulation platforms that enable virtual patient modeling. The book also addresses critical themes such as chronic disease management, emergency response optimization, ethical AI deployment, interoperability standards, and workforce readiness. Real-world case studies and future-focused chapters on cognitive twins and quantum simulation provide a rich, multidisciplinary perspective.

  • Next-Generation Onco-Therapeutics

    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Next-Generation Onco-Therapeutics explores the latest advancements in cancer treatment, focusing on personalized medicine and innovative therapeutic strategies. The book serves as a comprehensive resource for understanding how emerging technologies can reshape oncological care, providing insights into effective and compassionate patient management. Content explores cutting-edge developments in cancer therapies, featuring clinical examples and case studies that illustrate the practical application of new treatment modalities. It emphasizes the importance of integrative approaches that address the diverse needs of cancer patients, ensuring that healthcare professionals are equipped with the most current information in this rapidly evolving field. This book also addresses the urgent need for updated resources in oncological therapeutics, bridging the gap between traditional practices and modern innovations. By synthesizing diverse perspectives and evidence-based insights, it empowers healthcare providers, researchers, and policymakers to enhance treatment outcomes and improve patient well-being in the era of personalized medicine.

  • Current Approaches to Cryo-electron Microscopy

    • 1st Edition
    • Volume 223
    • English
    Cryo-electron microscopy (cryo-EM) has emerged as a transformative technique in structural biology, driving an exponential increase in the number of structures deposited in the Protein Data Bank. Current workflows now routinely achieve the near-atomic resolution essential for understanding the molecular pathology of neurodegenerative and metabolic disorders. This provides a comprehensive overview of the field, tracing the evolution from early structural studies to modern pipelines powered by deep-learning algorithms for helical reconstruction. We address the persistent bottleneck of sample preparation, detailing the physical challenges of fibril clumping and interfacial adsorption, alongside emerging solutions to these problems. Furthermore, we examine the complexities of structural polymorphism, discussing how environmental factors and seeding drive conformational diversity and how this heterogeneity impacts biochemical assays. Finally, we highlight the translational value of these high-resolution maps, demonstrating how they enable the rational, structure-based design of peptide inhibitors and small molecules capable of disaggregating pathogenic fibrils.

  • Biochar Applications

    Advances in Environmental Remediation and Resource Recovery
    • 1st Edition
    • Ahmad Hussaini Jagaba + 4 more
    • English
    Biochar Applications: Advances in Environmental Remediation and Resource Recovery provides a combined approach between environmental science and environmental engineering that involves the improvement of the natural environment, or the remediation, of polluted sites. In addition, it discusses bioprocess engineering, including the synthesis, modification, characterization, and management of biochar from biomass waste materials. The book includes coverage on sources, impacts, and applications of biochar that could potentially be used as catalysts to enhance environmental remediation and resource recovery processes. Examples of applied research that demonstrate the relationship between wastewater, soil, contaminated environments, remediation, resource recovery, sustainability, and circular bioeconomy are also included.The book bridges the gap between biochar applications in wastewater treatment, soil improvement, gas mitigation, and resource recovery.

  • Starch-Based Materials

    Principles and Applications
    • 1st Edition
    • Ming Miao + 1 more
    • English
    Starch-Based Materials: Principles and Applications explores the cutting-edge research and development of starches as biodegradable, renewable biomaterials addressing urgent environmental concerns associated with non-biodegradable polymers. This comprehensive volume delves into the structural characteristics of starches, recent advances in their physical, chemical, and enzymatic modifications, and emerging technologies that expand their use beyond traditional food applications. It highlights innovative approaches to enhance nutritional value and health benefits, including the design of gluten-free products and specialized foods, while also covering industrial uses such as hydrogels and controlled release systems. Despite extensive prior research on starch packaging and non-food uses, there is a significant gap in current literature regarding modern starch modifications and their multifunctional applications across food, pharmaceutical, medical, and biomaterial fields. This book addresses this gap by providing a timely, authoritative summary of recent scientific findings, aiming to stimulate innovation and sustainable development in starch utilization. It is an essential reference, particularly in courses related to food chemistry, food analysis, nutrition, packaging, pharmaceutical applications, and specialized medical fields such as controlled release technologies.

  • Polyphenols in Wound Healing

    • 1st Edition
    • Bushra Akhtar + 1 more
    • English
    Polyphenols in Wound Healing presents a comprehensive exploration of how naturally occurring compounds—polyphenol... a pivotal role in advancing wound care therapies. Divided into four thoughtfully curated sections, the book begins with an in-depth review of the science of wound healing, introducing readers to the fundamentals of skin physiology, the various types of wounds, and key therapeutic targets. Other sections delve into the world of polyphenols, offering detailed information on their natural sources, especially medicinal plants, and the techniques used for their extraction, isolation, and purification. A focus on how polyphenols act on biological pathways to support wound healing is also included.This includes mechanisms such as reducing inflammation, combating oxidative stress, modulating matrix metalloproteinases, enhancing collagen synthesis, and promoting tissue regeneration and angiogenesis. Each chapter is backed by current research, offering mechanistic insights that bridge traditional knowledge with modern biomedical science. This structured and progressive organization ensures that all key aspects of polyphenol-based wound healing are clearly presented and easy to follow, making the book highly accessible for researchers, clinicians, and students alike.

  • Basal Ganglia Dynamics

    From Motor Units to Networked Chaotic Oscillators
    • 1st Edition
    • Erwin B. Montgomery Jr.
    • English
    Basal Ganglia Dynamics: From Motor Units to Networked Chaotic Oscillators addresses the critical need for new theoretical frameworks in understanding the basal ganglia–thalamic–cor... system, particularly in the context of movement disorders such as Parkinson’s disease. Despite significant therapeutic advances, current dopamine replacement and Deep Brain Stimulation therapies remain limited due to incomplete and oversimplified prevailing theories. This reference provides a comprehensive alternative approach grounded in complexity science, nonlinear dynamics, and chaotic systems theory.The book's contents span foundational concepts, including motor unit orchestration, networked nonlinear oscillators, information theory, and methodological considerations. Detailed chapters cover the shortcomings of current models, the application of chaotic system mathematics to basal ganglia physiology, and the implications for pathophysiology and treatment. The book also includes extensive simulations, operational hypotheses, and a rigorous critique of existing paradigms that is supported by principles such as Causational and Informational Synonymy.

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