Skip to main content
Elsevier
View Cart

Books in Life sciences

BooksJournals

    • Drug Delivery Trends

      • 1st Edition
      • March 1, 2020
      • Ranjita Shegokar
      • English
      • Paperback
        9 7 8 0 1 2 8 1 7 8 7 0 6
      • eBook
        9 7 8 0 1 2 8 1 7 8 7 1 3
      Drug Delivery Trends examines a drift in the pharmaceutical field across the wide range of dosage forms, drug delivery systems (micro and nanoparticulate), at the regulatory front and on new types of therapies in the market. This volume additionally covers the challenges on drug delivery systems in terms of preclinical and current ways of determining quality and the options to solve the challenges associated with this. Most small-medium scale industries and academics struggle with initial regulatory challenges so a detailed discussion on regulatory trend covers the necessary basic understanding of regulatory procedures and provides the required guidance. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems.

    • Secondary Findings in Genomic Research

      • 1st Edition
      • February 29, 2020
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 5 4 9 2
      • eBook
        9 7 8 0 1 2 8 1 6 7 4 8 9
      Secondary Findings in Genomic Research offers a single, highly accessible resource on interpreting, managing and disclosing secondary findings in genomic research. With chapters written by experts in the field, this book is the first to concisely explain the ethical and practical issues raised by secondary genomics findings for a multi and interdisciplinary audience of genomic researchers, translational scientists, clinicians, medical students, genetic counselors, ethicists, legal experts and law students, public policy specialists and regulators. Contributors from Europe, North America, and Asia effectively synthesize perspectives from a spectrum of different scientific, societal, and global contexts, and offer pragmatic approaches to a range of topics, including oversight, governance and policy surrounding secondary genomic results, criteria for identifying results for return, communication and consent, stakeholders’ attitudes and perspectives, disclosing results, and clinical, patient-centered protocols.

    • Chickpea: Crop Wild Relatives for Enhancing Genetic Gains

      • 1st Edition
      • February 29, 2020
      • Mohar Singh
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 2 9 9 4
      • eBook
        9 7 8 0 1 2 8 1 8 3 0 0 7
      Chickpea: Crop Wild Relatives for Enhancing Genetic Gains explores aspects related to critical analysis on factors responsible for narrow genetic base of chickpea productions including domestication bottleneck, the level of diversity present in different cultivated and wild species, the uniqueness and usefulness of potential gene sources available and maintained in production systems across the globe, the level of genetic erosion both at landrace and species level over time and space etc. Despite considerable international investment in conventional breeding, production of chickpea has not yet been significantly improved beyond that achieved through its normal single domestication event and high self-pollination rate. Total annual pulse production of ~12 million tons (FAO 2016) is far below actual potential. Susceptibility to both biotic and abiotic stresses have created a production level bottleneck whose solution possibly lies in the use of crop wild relatives and other genetic traits cultivated by tailoring novel germplasm. Presenting options for widening the genetic base of chickpea cultivars by introgression of diverse genes available in distantly related wild Cicer taxa, thus expanding the genetic base and maximize genetic gains from the selection, it is necessary to accumulate other complimentary alleles from CWRs. This review will focus on present status of gene pool and species distribution, germplasm conservation, characterization and evaluation, problems associated with crop production, sources of target traits available in wild species, status of trait introgression in synthesizing new gene pool of chickpea along with progress made in chickpea genomics. An edited book with contributions from leading scientists, this information will guide and inform chickpea breeders, PGR researchers and crop biologists across the world.

    • Giardia and Giardiasis - Part B

      • 1st Edition
      • Volume 107
      • February 28, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 4 7 5 7
      • eBook
        9 7 8 0 1 2 8 2 2 1 9 7 6
      Giardia and Giardiasis Volume 107-Part B, in the Advances in Parasitology series, is dedicated to aspects of cytoskeletal structure of this parasite with an emphasis on insights of new components and their function in trophozoites. Further, microtubule function and its critical involvement in motility, attachment, mitosis and cell division as well as in transitions between developmental stages are reviewed. Also a comprehensive revision in the progress of tools to explore and understand the functional biology of Giardia, its coding and non-coding genes, features and cellular and molecular biology is contained in this volume. Additionally, an exciting perspective on the interactions between Giardia and intestinal epithelial cell by reviewing transcriptomic and proteomic investigations is included along with a state-of-the art of the understanding pathophysiology of giardiasis and of how Giardia can cause post-infectious and extra-intestinal complications. A complete review of current knowledge including commonly prescribed drugs, causes of therapeutic fails, drug resistance mechanisms, strategies for the discovery of new agents for alternative drug therapies is covered.

    • Tumor Immunology and Immunotherapy - Integrated Methods Part A

      • 1st Edition
      • Volume 635
      • February 28, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 1 8 6 7 7 0
      • eBook
        9 7 8 0 1 2 8 1 8 8 7 5 0
      Tumor Immunology and Immunotherapy Integrated Methods - Part A, Volume 635 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Specific chapters to this release include Deconvolution of the immunological contexture of mouse tumors with multiplexed immunohistochemistry... High-dimensional multiplexed immunohistochemical characterization of immune contexture in human cancers, Multiplex assay by IHC for melanoma tumor microenvironment evaluation, Characterization of the tumor immune microenvironment by multispectral image analysis of multiplex immunofluorescence images, Phenotyping of immune cells in situ using multispectral imaging quantification, and much more.

    • Biscuit, Cookie and Cracker Process and Recipes

      • 1st Edition
      • February 28, 2020
      • Glyn Barry Sykes + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 0 5 9 8 3
      • eBook
        9 7 8 0 1 2 8 2 0 6 1 3 3
      Biscuit, Cookie and Cracker Process and Recipes: A practical reference for a wide range of recipes and production information for crackers, snack crackers, semi-sweet biscuits, short doughs, cookies and sandwich biscuits. These recipes have been developed in Europe, Asia, Australia, North America and South America. Beginning with an explanation of the production process and formulations, this book provides easy-access information for developing new biscuits, cookies and crackers for international markets. All the process details, formulations, technical information are based on the notes and files of the late Glyn Sykes. Glyn gained wide experience over a working lifetime in the biscuit baking industry, working with over fifty biscuit manufacturers world-wide. Glyn Sykes family have made the information available for the new book, which is a valuable reference for professionals in the biscuit baking industry and students in the food technology field.

    • Toxoplasma Gondii

      • 3rd Edition
      • February 28, 2020
      • Louis M. Weiss + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 1 5 0 4 1 2
      • eBook
        9 7 8 0 1 2 8 1 5 0 4 2 9
      Toxoplasma gondii: The Model Apicomplexan - Perspectives and Methods, Third Edition, reflects significant advances in the field in the last five years, including new information on the genomics, epigenomics and proteomics of T. gondii, along with a new understanding of the population biology and genetic diversity of this organism. This edition expands information on the effects of T. gondii on human psychiatric disease and new molecular techniques, such as CAS9/CSPR. T gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists.

    • Advances in Clinical Chemistry

      • 1st Edition
      • Volume 95
      • February 27, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 1 1 6 5 6
      • eBook
        9 7 8 0 1 2 8 2 1 1 6 9 4
      Advances in Clinical Chemistry, Volume 95, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release including sections on Advances in diagnostic microfluidics, Vascular and valvular calcification biomarkers, Long noncoding RNAs in cancer: From discovery to therapeutic targets, Exosomes of male reproduction, Tryptophan in health and disease, Biochemistry of blood platelet activation, and the beneficial role of plant oils in cardiovascular diseases.

    • Systems Simulation and Modeling for Cloud Computing and Big Data Applications

      • 1st Edition
      • February 26, 2020
      • Dinesh Peter + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 7 7 9 0
      • eBook
        9 7 8 0 1 2 8 1 9 7 8 0 6
      Systems Simulation and Modelling for Cloud Computing and Big Data Applications provides readers with the most current approaches to solving problems through the use of models and simulations, presenting SSM based approaches to performance testing and benchmarking that offer significant advantages. For example, multiple big data and cloud application developers and researchers can perform tests in a controllable and repeatable manner. Inspired by the need to analyze the performance of different big data processing and cloud frameworks, researchers have introduced several benchmarks, including BigDataBench, BigBench, HiBench, PigMix, CloudSuite and GridMix, which are all covered in this book. Despite the substantial progress, the research community still needs a holistic, comprehensive big data SSM to use in almost every scientific and engineering discipline involving multidisciplinary research. SSM develops frameworks that are applicable across disciplines to develop benchmarking tools that are useful in solutions development.

    • The Electronic Health Record

      • 1st Edition
      • February 26, 2020
      • Eike-Henner W. Kluge
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 0 4 5 0
      • eBook
        9 7 8 0 1 2 8 2 2 0 4 6 7
      The Electronic Health Record: Ethical Considerations analyses the ethical issues that surround the construction, maintenance, storage, use, linkage, manipulation and communication of electronic health records. Its purpose is to provide ethical guidance to formulate and implement policies at the local, national and global level, and to provide the basis for global certification in health information ethics. Electronic health records (EHRs) are increasingly replacing the use of paper-based records in the delivery of health care. They are integral to providing eHealth, telehealth, mHealth and pHealth - all of which are increasingly replacing direct and personal physician-patient interaction - as well as in the developing field of artificial intelligence and expert systems in health care. The book supplements considerations that are raised by national and international regulations dealing with electronic records in general, for instance the General Data Protection Regulation of the European Union. This book is a valuable resource for physicians, health care administrators and workers, IT service providers and several members of biomedical field who are interested in learning more about how to ethically manage health data.

Related subjects

Agricultural and biological sciences

Drug discovery

Immunology

Microbiology and virology

Neuroscience

Pharmaceutical sciences

Pharmacology

Toxicology