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Elsevier

Books in Life sciences

  • Artificial Intelligence in Immunoengineering

    Methods, Models, and Translational Applications
    • 1st Edition
    • Steven Zanganeh + 1 more
    • English
    Artificial Intelligence in Immunoengineering: Methods, Models, and Translational Applications examines how AI reshapes immunoengineering to design immune-modulating biomaterials, imaging systems, and diagnostic tools. The book presents an integrated view of data-driven approaches that accelerate discovery and translation in biomedicine. It surveys biological data from single-cell to spatial omics and proteogenomics and offers practical machine learning frameworks, generative and mechanistic models, and multimodal integration strategies. Sections address bench-to-bedside translation, validation pipelines, and regulatory considerations for AI-enabled immunoengineering tools.The book highlights the rapid progress of multidisciplinary research within immunotherapy and immunoengineering. Looking forward, the prospects of immunoengineering appear promising, with further advancements in disease prevention, diagnostics, and treatment on the horizon. Graduate students, academic researchers, clinician-scientists... and computational biologists will gain standardized workflows, mechanism-aware modeling, and reproducible pipelines that advance immunotherapies and diagnostics from concept to clinical impact.

  • Crossing Viral Boundaries

    Zoonotic Infections and Strategies for Public Health Preparedness
    • 1st Edition
    • Zubaida Hassan + 1 more
    • English
    Crossing Boundaries in Zoonotic Viral Infections and Strategies for Public Health Preparedness addresses the urgent need for a deeper understanding of zoonotic viruses, which pose significant public health threats and require improved preparedness. It provides up-to-date insights into the biology, transmission, and epidemiology of key zoonotic virus families, explores the associated human diseases, and discusses diagnostic and treatment strategies. This comprehensive book systematically explores major zoonotic virus families, beginning with an introductory overview of virology, zoonoses, and human-animal interactions, setting the stage for understanding virus transmission and public health challenges. Each subsequent chapter delves into a specific virus family—covering their discovery, biology, transmission routes, cellular targets, disease mechanisms, diagnostics, treatments, outbreak case studies, and surveillance strategies. Additionally, the book introduces simulation tools for modeling viral pathogenesis and predicting cross-species transmission. It concludes with a synthesis of key themes, emphasizing global health policies, preparedness, and future directions for managing zoonotic viral threats effectively equipping future scientists with essential knowledge and resources to combat emerging zoonotic infections.

  • Contemporary Challenges in Food Packaging

    Innovation, Consumer Acceptance, Sustainability, and Regulatory Considerations
    • 1st Edition
    • Sukvinder K. Jassi + 1 more
    • English
    Contemporary Challenges in Food Packaging: Innovation, Consumer Acceptance, Sustainability, and Regulatory Considerations is an essential resource for academic and industry professionals that explores the complexities of creating innovative, sustainable, safe packaging that attracts consumers within the context of sustainability. This comprehensive text examines the misunderstandings that lead not only consumers but also scientists and industry professionals, to question the necessity and sustainability of packaging materials without fully grasping their essential roles in environmental safety, food preservation, and effective packaging waste management. By highlighting the vital role packaging plays in consumer acceptance, and the circular economy, this book serves as a bridge between academic research and practical application, and gives readers the knowledge to navigate existing challenges in the field. Organized into seven sections,Contemporar... Challenges in Food Packaging: Innovation, Consumer Acceptance, Sustainability, and Regulatory Considerations features 19 chapters that cover everything from the historical evolution of food packaging to the latest innovations in smart packaging technologies. Readers will explore the implications of environmental sustainability, the adaptation to a circular economy model, and the emerging solutions for effective waste management. With contributions from leading experts, the text identifies best practices and innovative strategies that address regulatory requirements, and consumer and industry needs.

  • The Plasticity of Sex

    The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior
    • 2nd Edition
    • Marianne Legato J.
    • English
    The Plasticity of Sex: The Molecular Biology and Clinical Features of Genomic Sex, Gender Identity and Sexual Behavior, Second Edition offers a thorough exploration of the biological, clinical, and social dimensions of human sexuality. This updated edition emphasizes the increasing recognition of the diversity of sexual identities and behaviors, particularly the spectrum between traditional male and female categories. It consolidates evidence-based research on the molecular and developmental biology of sex, gender identity, and sexual behavior, presenting a comprehensive resource for biomedical researchers, clinicians, and medical students. A key theme of this edition is the growing understanding of human sexuality as fluid and diverse, shaped by a variety of genetic, hormonal, and environmental factors. Over recent decades, there has been heightened interest in issues like gender identity, genital ambivalence, and sexual transition, with both the general public and medical professionals seeking more knowledge and guidance on these topics. The book underscores the need for a more inclusive approach, incorporating voices from diverse communities and recognizing the importance of broadening the scope of research beyond narrow sample sizes and traditional binary frameworks. The new edition highlights the ongoing challenges in understanding and addressing variations in human sexuality and the need for continued dialogue between science, society, and legal systems to create more inclusive frameworks for care and support. This work serves as an essential reference for anyone involved in the study or treatment of human sexuality.

  • Critical Care in Pregnant Patients

    Ultrasound
    • 1st Edition
    • Jorge Hidalgo + 3 more
    • English
    Critical Care in Pregnant Patients: Ultrasound, a volume in the Critical Care Obstetrics series, is a novel reference to educate physicians, nurses, and all allied healthcare personnel caring for pregnant women with various health compromises. The book's chapters reflect the growing scope of critical care obstetrics and the increasing importance and recognition of the hospital structure's field. All intensivists, regardless of primary discipline, must possess a core set of critical care skills to manage critically ill patients. The book's authors have gathered the best evidence-based material explicitly focused on how ultrasound can successfully manage potential scenarios of common and rare health complications. Users will find the basics of ultrasound and the latest technological advances of ultrasound that foster research and improve health outcomes in pregnant patients.

  • Advanced and Sustainable Biotechnologies from Fungi

    Functional Foods and Nutraceutical Production
    • 1st Edition
    • Pragya Tiwari + 1 more
    • English
    Advanced and Sustainable Biotechnologies from Fungi: Functional Foods and Nutraceutical Production provides insights into existing and emerging fungal biotechnologies, along with advances in high-throughput technologies to enhance the sustainable production of bio-based functional foods and nutraceuticals of fungal origin. Focusing on the emerging, global concern of hunger and malnutrition, this book explains how fungi-based biotechnologies offer prospective solutions to address the global food shortage using functional foods and nutraceuticals. Chapters cover the major portion of novel sources and various biotechnological approaches used for the production of functional foods and nutraceuticals from microorganisms and mushrooms and their applications in the industry. In addition, the book includes the existing and emerging biotechnological trends and approaches in enhanced production of Functional food and Nutraceuticals of fungal origin, such as Omics-guided advances, computational strategies, and biotechnological tools. 3D printed fungal food products, and social, ethical, and regulatory aspects of functional food and nutraceutical products are also discussed. Authored by a team of experts in the field of fungi biotechnology, this book serves as a reference material for food microbiologists, food scientists, and pharmaceutical professionals for the development of new functional foods and nutraceuticals.

  • Network Pharmacology in Natural Products Drug Discovery

    • 1st Edition
    • Devesh Tewari + 1 more
    • English
    Network Pharmacology in Natural Products Drug Discovery addresses the critical intersection of network pharmacology and natural product research, a rapidly evolving field essential for modern drug discovery. The book's content begins with foundational concepts of network pharmacology followed by an exploration of natural products as therapeutic agents. Its comprehensive Table of Contents covers a diverse range of topics, including omics integration, metabolomics, and case studies on various health conditions, thus ensuring a holistic understanding of the subject matter. Each chapter not only presents theoretical insights but also emphasizes practical applications, case studies, and emerging trends in network pharmacology related to natural products.The book empowers its audience by providing them with essential tools and methodologies to integrate network pharmacology into their research. It highlights the advantages of utilizing computational approaches alongside experimental validation, enabling researchers to uncover the mechanisms of action of natural compounds. With a focus on real-world applications, this reference is invaluable for advancing drug discovery and therapeutic development.

  • Aging and Troponin

    Clinical Implications and Uses Beyond Diagnosis
    • 1st Edition
    • Gary Tse + 3 more
    • English
    Aging and Troponin: Clinical Implications and Uses Beyond Diagnosis examines the multifaceted role of troponin in clinical medicine, with a special focus on aging. This comprehensive reference provides essential technical knowledge, diagnostic and prognostic applications, and model development insights from leading experts in clinical biochemistry, pathology, and epidemiology. The book emphasizes the impact of aging on troponin test results and their interpretation, addressing age-related disorders such as renal failure. Sections cover the technical aspects of troponin assays, comparing traditional and high-sensitivity assays and exploring point-of-care testing advancements.The book also examine age-related changes and intra- and inter-individual variability in troponin levels, focuses on diagnostic applications, including troponin as a biomarker for cardiac injury and dysfunction, and the effects of age, sex, and renal impairment on diagnostic sensitivity and specificity, and discusses troponin's prognostic value for mortality in various conditions, including heart disease, sepsis, and COVID-19, and its role as a marker of organ biological age. The final section offers cutting-edge insights into the clinical applicability of troponin testing, highlighting the benefits of incorporating high-sensitivity assays into clinical workflows and providing perspectives and age-related considerations from practicing physicians on implementation and evidence-based practice.

  • Evidence Based Diagnosis and Management of Testicular Tumors

    • 1st Edition
    • Axel Heidenreich
    • English
    Evidence Based Diagnosis and Management of Testicular Tumors is a comprehensive reference that addresses the current needs of urologists, oncologists, and related specialists involved in testicular cancer care. This book synthesizes the latest research, clinical guidelines, and expert insights to facilitate accurate diagnosis, staging, and personalized treatment strategies. It emphasizes a multidisciplinary approach, integrating pathology, molecular genetics, imaging, and surgical techniques, to optimize patient outcomes and minimize long-term toxicity. The contents are organized into key sections covering epidemiology, pathology, staging, diagnostic evaluation, disease management, and follow-up. Each chapter begins with case scenarios and interactive questions, fostering active learning and decision-making skills. The book also dedicates sections to rare tumors and pediatric cases, ensuring broad applicability across age groups and tumor types. Visual content, including figures, flow charts, tables, and videos, enhances comprehension and procedural training. This reference aims to bridge the knowledge gap in current testicular cancer management, providing practitioners with practical, guideline-conforming advice. It supports clinicians in delivering individualized, risk-adapted care, ultimately improving survival rates and quality of life for patients. By combining expert perspectives with evidence-based protocols, this book serves as an essential resource for advancing clinical practice in testicular oncology.

  • Cell Death Part G

    • 1st Edition
    • Volume 214
    • English
    Cell Death Part G presents current methods and advances for studying the mechanisms, regulation, and biological significance of cell death. The volume covers experimental and analytical approaches relevant to apoptosis, necrosis, autophagy, and other cell death pathways in both basic and translational research.

  • Artificial Intelligence in Clinical Medicine

    General Concepts and Specific Applications
    • 1st Edition
    • Marianne Legato J. + 1 more
    • English
    Artificial Intelligence in Clinical Medicine: General Concepts and Specific Applications explores the evolution and application of artificial intelligence (AI) in medicine, highlighting both its potential and challenges. The initial discussion outlines past failures in integrating AI into healthcare, followed by a review of FDA-approved AI medical devices and their implications for diagnostics. Subsequent sections examine the transformative impact of large language models, the ethical application of AI in clinical settings, and the role of AI in enhancing patient safety. Various specialties, such as cardiology and pulmonary disease, illustrate AI's capabilities in improving diagnostics and treatment. The discussions extend to diabetes care, dermatology, obstetrics, and radiology, emphasizing the need for ethical considerations and quality assessments to ensure AI aligns with human values and improves patient outcomes across diverse healthcare contexts.

  • Neurochemical Substrates of Addiction Medicine

    • 1st Edition
    • Mohammad Banazadeh + 2 more
    • English
    Neurochemical Substrates of Addiction Medicine offers an in-depth exploration of the complex interplay between neurochemistry and addiction, providing critical insights for researchers, clinicians, and students alike. This book is structured into four comprehensive sections, beginning with an examination of the distribution of neurotransmitters across key brain circuitry involved in addiction, such as the mesolimbic, striatal, frontal, insular, and thalamic systems. Each chapter meticulously describes how these circuits contribute to addictive behaviors and the underlying neurobiological mechanisms. The second section delves into the major neurotransmitter systems—including dopaminergic, glutamatergic, GABAergic, adrenergic, serotonergic, cholinergic, endogenous opioid, and purinergic systems—highlighting their roles in addiction.Following this, the book addresses the neuropharmacology of various drugs of abuse, including nicotine, opioids, alcohol, psychomotor stimulants, cannabinoids, psychedelics, sedative-hypnotics, caffeine, and antihistamines, detailing how these substances alter neurochemical pathways. The final section expands the discussion to behavioral addictions, exploring the neurochemical substrates associated with disorders such as pathological gambling, internet use, sexual addiction, and binge eating.

  • Proteolytic Enzymes and their Inhibitors in Infectious Pathogens

    • 1st Edition
    • Theresa Coetzer
    • English
    Proteolytic enzymes are found in all life forms, where they catalyze peptide bond hydrolysis during essential biological processes. Proteases of various pathogens have also been shown to use endogenous protease inhibitors to regulate the activity of host proteolytic enzymes encountered during infection.Proteolyti... Enzymes and their Inhibitors in Infectious Pathogens brings together key experts to provide a thorough discussion of proteolytic enzymes and their endogenous inhibitors found in parasites, bacteria, and viruses. The book focuses on the respective roles of the different catalytic classes of proteolytic enzymes and their protein-protease inhibitors at the host-infectious organism interface, and how this knowledge may inform drug and vaccine design. Following a foundational overview of proteases and macromolecular inhibitors of pathogenic organisms, authors discuss recent research on distinct classes of proteolytic enzymes in pathogens. Classes include aspartic proteases, cysteine proteases, metalloproteases, serine proteases, and threonine proteases with experts contributing chapters on distinct enzymes and inhibitors. New methods to identify protease substrates and inhibitors are also provided, with step-by-step protocols to advance new research and drive drug discovery.

  • Rational 'Co-Design' of Targeted Anticancer Therapeutics

    Integrating Immuno-Oncology, Biomaterials, and Translational Systems
    • 1st Edition
    • Y. Manojkumar + 3 more
    • English
    Rational 'Co-Design' of Targeted Anticancer Therapeutics: Integrating Immuno Oncology, Biomaterials, and Translational Systems presents a unified, system level framework that designs molecules, carriers, and delivery pathways concurrently for clinically translatable cancer therapies. The book details how electronic structure, molecular recognition, biomaterial compatibility, immune microenvironment dynamics, and ADMET/AI models integrate into end to end decision frameworks—from in silico prediction to experimental validation and regulatory readiness. Readers gain a pragmatic path to faster, safer translation: case informed guidance, co design checklists, and criteria for affordability, scalability, and sustainability enable researchers and advanced students to move beyond fragmented, sequential development toward robust therapeutic systems.

  • Neurobiology of Depression

    Road to Novel Therapeutics
    • 2nd Edition
    • João L. de Quevedo + 2 more
    • English
    Neurobiology of Depression: Road to Novel Therapeutics, Second Edition follows the success of the first edition, synthesizing the basic neurobiology of major depressive disorder (MDD) with discussions on the latest research advances, including interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and novel optogenetic techniques revolutionizing depression research. This new edition includes comprehensive foundational understandings of the disorder and highlights recent advances, aiding advanced students and researchers in their understanding of MDD. The book introduces new chapters exploring groundbreaking topics such as the neurobiology of treatment-resistant depression, the antidepressant mechanisms of ketamine, and the link between depression and Alzheimer's disease. Additionally, it covers the neurobiology of suicide in depression, the impact of psychedelics as therapy, and the unique aspects of bipolar depression. This edition also examines computational models in depression, the neurobiology of psychotherapy, and the putative mechanisms of action for vagus nerve stimulation as a therapeutic approach. These additions help to provide a broader and more comprehensive understanding of depression and its treatment.

  • Food Bioactives and Their Role in Human Health and Nutrition

    • 1st Edition
    • Sajad Ahmad Wani + 1 more
    • English
    Food Bioactives and their Role in Human Health and Nutrition, is a comprehensive resource offering an in-depth look at essential bioactive compounds, such as polyphenols, flavonoids, plant sterols, omega-3 fatty acids, and probiotics, highlighting their importance in promoting health and preventing chronic diseases. Readers will gain insights into the chemical structures, sources, and bioavailability of these compounds, along with practical dietary recommendations tailored to address common lifestyle-related health challenges such as obesity, diabetes, and cardiovascular disease. Food Bioactives and their Role in Human Health and Nutrition, also addresses emerging trends and challenges in the field, including personalized nutrition approaches and the integration of functional foods and nutraceuticals. It examines the role of food processing on the stability of bioactives, ensuring that health professionals are equipped with the latest knowledge to optimize nutritional strategies.

  • Primer on Cerebrovascular Research

    • 1st Edition
    • Dong-Eog Kim + 3 more
    • English
    Primer on Cerebrovascular Research provides both clinical and basic cerebrovascular knowledge that is required for physicians, vascular researchers, biomedical students, and trainees to understand or conduct evidence-based clinical practice and cutting-edge experimental research. This book outlines how to a design experimental cerebrovascular research in the context of clinical relevance, conduct the study using proper methods, analyze the data accurately, and make conclusions in an unbiased and statistically correct way. Chapters will include representative examples and experimental protocols.

  • Pediatric Culinary Medicine

    Evidence, Opportunities, and Practice
    • 1st Edition
    • Maria R. Mascarenhas + 2 more
    • English
    Pediatric Culinary Medicine: Evidence, Opportunities, and Practice is a groundbreaking resource authored by diverse pediatric leaders, offering a comprehensive exploration of the rapidly evolving field of food as medicine. This book uncovers the history, benefits, and current research landscape, highlighting future opportunities for advancing pediatric health & development through culinary approaches. It provides practical insights into supporting children from diverse cultural and socioeconomic backgrounds, including those managing chronic conditions and those seeking to optimize wellness. Perfect for both newcomers and seasoned practitioners, this book will inspire innovative ways to integrate food into pediatric care. Packed with expert knowledge, this volume covers the evolution of culinary medicine, current research gaps, and practical strategies for real-world application in a pediatric setting. It features detailed chapters on dietary patterns that promote child health, culturally relevant practices, and policy opportunities, along with pathways for training and education, offering essential guidance for translating culinary medicine into meaningful, sustainable programs that improve pediatric health outcomes. Designed to serve a broad audience, Pediatric Culinary Medicine: Evidence, Opportunities, and Practice is an invaluable tool for researchers seeking to identify gaps and develop impactful studies and for pediatric healthcare providers aiming to implement evidence-based practices. It provides the foundational knowledge, successful models, and training resources needed to harness the power of food to transform child health. This book is a must-have for anyone committed to shaping the future of pediatric nutrition and wellness through culinary medicine.

  • Combinatorial Enzyme Therapy Against ESKAPE Pathogenic Biofilms

    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Combinatorial Enzyme Therapy Against ESKAPE Pathogenic Biofilms offers the latest insights into ESKAPE pathogen biofilms, including their formation, structure, and resistance mechanisms. In addition, the book highlights innovative therapeutic strategies to combat them, with a specific focus on combinatorial enzyme therapies. It begins with an overview of the significant burden these pathogens impose across healthcare and the food industry, laying the groundwork for understanding the intricate relationship between antibiotic resistance and biofilm dynamics. The book advocates for novel approaches through combinatorial enzymatic therapy, detailing the mechanisms and synergies of various enzymes in effectively dismantling biofilms.With insights into cutting-edge delivery systems, including nanotechnology and the integration of CRISPR-Cas systems and artificial intelligence, the book charts a course for the future of advanced therapeutic strategies. It concludes by addressing regulatory considerations, positioning combinatorial enzyme therapy as a promising frontier in the fight against persistent infections caused by ESKAPE pathogens.

  • Probiogenomics and Probiomics

    Concepts, Techniques, Applications, and Achievements
    • 1st Edition
    • Debmalya Barh + 1 more
    • English
    Probiogenomics and Probiomics: Concepts, Techniques, Applications, and Achievements is a pioneering reference book that marks a significant milestone in the emerging fields of probiogenomics and probiomics. As the first comprehensive resource in these disciplines, the book offers a detailed exploration of how genetic insights and omics technologies are revolutionizing our understanding of probiotics and their application in health and disease. Spanning three detailed sections, the book begins by grounding readers in the fundamental concepts of probiotics, including their roles in health enhancement and disease prevention. It progresses into a deep dive into advanced genomic and post-genomic technologies, revealing how these tools are used to dissect and harness the health-promoting capacities of probiotics. From the structure and function of probiotic genomes to the cutting-edge applications in synthetic biology and multi-omics, the book encapsulates the latest advancements and methodologies in the field. The final sections focus on the practical and clinical applications of these microbial marvels, discussing their impact on healthcare, biotechnology, and therapeutics. Whether it's developing new biotechnological products or enhancing therapeutic efficacy, this book covers a broad spectrum of applications, making it an invaluable resource for undergraduate and postgraduate students, researchers, clinicians, and industry professionals involved in drug and probiotics development. With contributions from over ten global experts, "Probiogenomics and Probiomics" not only educates but also inspires, providing a thorough understanding of modern probiogenomics and its potential to shape the future of personalized medicine and healthcare.

  • Pediatric Gastroenterological Diagnosis

    A Diagnostic Primer
    • 1st Edition
    • Richard Thomas Lee Couper
    • English
    Pediatric Gastroenterological Diagnosis: A Diagnostic Primer focuses on the theoretical aspects of diagnosing pediatric gastroenterology diseases, including historical and current information. Sections cover pediatric gastroenterology diseases and provide practical advice for quick and accurate diagnosis. In addition, the book provides multiple pediatric tables and references, as well as brief clinical vignettes that identify potential pitfalls clinicians may encounter. This is the perfect reference for clinicians who struggle with complex diagnosis and problem-solving, and will be ideal for pediatric gastroenterology trainees and pediatric gastroenterologists.

  • Herbals and Their Antioxidant Effects on Human Health

    • 1st Edition
    • Süleyman Kaplan
    • English
    Herbals and their Effects on Human Health provides a comprehensive exploration of the diverse bioactive components found in medicinal plants and their relevance to human health. Divided into three distinct sections, beginning with a thorough examination of bioactive components and their health benefits, readers will discover the intricacies of traditional practices such as Ayurveda, the role of phytotherapy in managing metabolic disorders, and the therapeutic potential of antioxidants in various health contexts, including skin health and cardiovascular disease. The book further enhances its scientific rigor by including light and electron microscopic images that illustrate tissue and organ structures affected by herbal interventions. Subsequent sections focus on bioactive foods, highlighting their therapeutic effects through in-depth discussions on specific herbals and plants such as garlic, curcumin, garcinia kola and blueberries. This section not only examines their protective roles in conditions like chronic inflammation and diabetes but also addresses lesser-known foods and their health-promoting properties. The final section highlights the mechanisms of action of these compounds, examining their impact on biological systems and their neuroprotective effects.Herbals and their Effects on Human Health is an essential resource for food scientists, physicians, biomedical researchers, pharmacologists, and nutritionists seeking to deepen their understanding of how herbal and bioactive components influence health and wellness.

  • Pharmaceutical Microbiology

    Essentials for Quality Assurance and Quality Control
    • 2nd Edition
    • Tim Sandle
    • English
    The second edition of Pharmaceutical Microbiology: Essentials for Quality Assurance and Quality Control is an authoritative reference designed for pharmaceutical microbiologists, sterilization personnel, and production scientists. It addresses the evolving landscape of microbiological standards, regulatory requirements, and scientific innovations in the pharmaceutical industry. The book emphasizes the importance of maintaining compliance through updated practices, new testing methodologies, and comprehensive contamination control strategies, ensuring safety and quality in pharmaceutical manufacturing.This book provides invaluable insights for professionals seeking to optimize microbiological quality assurance, meet regulatory expectations, and adopt innovative technologies. It supports laboratory managers, microbiologists, and quality assurance specialists in implementing best practices, ensuring product safety, and staying abreast of scientific progress in pharmaceutical microbiology.

  • Precision Care in Gastroesophageal Reflux Disease

    Using Pathophysiology and Clinical Insights towards a Personalized Approach
    • 1st Edition
    • Walter W. Chan + 1 more
    • English
    Precision Care in Gastroesophageal Reflux Disease: Using Pathophysiology and Clinical Insights towards a Personalized Approach addresses the urgent need for personalized approaches in managing GERD. This reference explores the evolving understanding of GERD pathophysiology and the necessity to move beyond generalized treatments toward disease phenotyping and targeted therapy. It emphasizes integrating clinical insights with emerging diagnostic technologies to optimize patient outcomes. The book’s content is organized into sections covering disease phenotypes and pathophysiology, clinical presentation, diagnostic techniques, and management approaches. Chapters include detailed discussions on symptom mechanisms, hypervigilance, diagnostic endoscopy, esophageal function testing, and both medical and surgical treatment options. Contributions from international experts provide evidence-based perspectives on utilizing scoring systems, ancillary tests, and adjunctive therapies to support precision care. Precision Care in Gastroesophageal Reflux Disease equips clinicians, advanced practice providers, and trainees with state-of-the-art knowledge to tailor evaluation and treatment strategies for diverse GERD phenotypes. It is an essential resource for those seeking to apply precision medicine principles in gastroenterology, enhancing diagnostic accuracy and therapeutic effectiveness in clinical practice.

  • RNA-Binding Proteins Part B

    • 1st Edition
    • Volume 744
    • English
    Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Understanding Mycotoxins

    Toxicity, Detection, Risk Assessment, and Prevention Strategies
    • 1st Edition
    • Vinay B. Raghavendra + 1 more
    • English
    Understanding Mycotoxins: Toxicity, Detection, Risk Assessment, and Prevention Strategies offers an in-depth exploration of their toxicological impact, detection techniques, and strategies for prevention and risk management. It addresses the critical health risks associated with mycotoxin exposure, including acute poisoning, carcinogenicity, and neurotoxicity, emphasizing the importance of accurate detection and effective mitigation measures. The book provides evidence-based insights into the mechanisms of mycotoxin toxicity, emerging threats, and the latest technological advances in analysis and detection. The book is structured into three detailed sections. The first section covers the fundamental aspects of mycotoxins, including their structures, biosynthetic pathways, sources of contamination, and health risks, supported by discussions on sampling, analytical techniques such as chromatography and spectroscopy, and the link between mycotoxins and diseases like cancer and neurological disorders. The second section delves into modern detection methods, highlighting advanced electrochemical sensors, immunoassays, biosensors, and innovative approaches utilizing machine learning, artificial intelligence, and nanotechnology for rapid and accurate identification of mycotoxins in various food matrices. The final section focuses on prevention and risk management, exploring detoxification strategies, mitigation techniques—including physical, chemical, biological, and emerging plasma and nanotechnology-based methods—and the regulatory frameworks that underpin safe food production and handling practices, aiming to reduce exposure and protect vulnerable populations globally.

  • Introduction to Practical EPR Spectroscopy

    • 1st Edition
    • Wilfred R. Hagen
    • English
    Introduction to Practical Electron Paramagnetic Resonance (EPR) Spectroscopy of randomly oriented molecules finds wide application in chemistry, biology, and many other related disciplines. This graduate-level text guides the reader along the winding road of the undocumented pitfalls and unwritten rules-of-thumb that come with undertaking practical EPR spectroscopy. The aim is to provide a truly practical and complete introduction to this widely used method. With the required quantum mechanics limited to an indispensable minimum, the book comprehensively treats the basic theoretical and practical aspects of the methodology to educate the reader to the level of an independent EPR researcher in all aspects, including problem posing, sample preparation, machine operation, data collection and interpretation, numerical analysis, and scientific reporting.Many EPR books have been written as expositions of the quantum-mechanical background of magnetic resonance, but without addressing critical practical questions in the lab including but not limited to:what knobs to turnhow to make sampleswhat programs to use (or not use)how to present experimental resultsIntroduction to Practical EPR Spectroscopy offers a complete preparation (both theoretical and practical) to be an independent EPR spectroscopist in what may be a non-specialist laboratory. It is written primarily for PhD, master’s and postdoctoral students and their tutors across biochemistry, organic, inorganic, bioinorganic and physical chemistry, molecular biology, microbiology, molecular physics, materials science, and geology.

  • The Transcription Factor NRF2

    Biology, Disease and Translational Opportunities
    • 1st Edition
    • Narendra Kumar Sharma + 1 more
    • English
    The Transcription Factor NRF2: Biology, Disease and Translational Opportunities offers a detailed and authoritative reference on NRF2, a key regulator of cellular defence against oxidative stress. This book thoroughly examines the latest research, from molecular mechanisms to clinical applications, highlighting NRF2’s essential function in cell protection, disease prevention, and its promise as a therapeutic target. The book opens with an introduction to NRF2 and its role in cellular homeostasis before exploring its molecular structure, regulation and signalling mechanisms. Its antioxidant response is then discussed, followed by its impact on inflammation, autophagy, and resistance to environmental and chemical stresses. Later chapters cover NRF2’s role in cancer, neurodegenerative, cardiovascular, autoimmune, and metabolic diseases. Cutting-edge techniques are also provided, including AI-based and systems biology tools. Case studies emphasize translational potential and therapeutic development.The Transcription Factor NRF2: Biology, Disease and Translational Opportunities equips researchers, clinicians, and advanced students with critical knowledge to understand NRF2’s multifaceted functions and therapeutic potential. It serves as an essential guide for advancing research and strategies targeting NRF2 in a diverse array of medical conditions, and is an ideal reference for those working across cell biology, molecular biology, biomedicine and related fields.

  • Inherited Metabolic Diseases and the Brain

    • 1st Edition
    • Fanny Mochel + 2 more
    • English
    Inherited Metabolic Diseases and the Brain explores the latest research on the neurological aspects of inherited metabolic diseases such as epilepsy, encephalotomy and more. With a strong research driven foundation and clinical applications, this book provides a primer which will help practicing pediatric and adult neurologists recognize, diagnose and treat neurometabolic disorders. This volume will also present a number of more common disorders in more detail, describing the variability in clinical presentation, the life course of the disease and the intricacies of diagnosis and treatment.

  • Fermented Foods in Health and Disease Prevention

    • 2nd Edition
    • Juana Frías + 2 more
    • English
    Fermented Foods in Health and Disease Prevention, Second Edition examines the significance of fermented foods to public health. The book presents the latest scientific evidence, showing the health-promoting components produced upon fermentation from a diversity of food matrices. The content includes the definition and characterization of traditional and innovative fermented foods, their mechanisms of action, and the evidence for effects on health and disease in humans. Putative health effects associated with direct interactions between the ingested live microorganisms and the host (probiotic effect), or indirectly, through ingestion of microbial metabolites and products of fermentation (biogenic effect) are discussed.This book will provide the food industry with new insights on the development of value-added fermentation, while also presenting nutritionists and dieticians with a useful resource to help them develop strategies to assist in the prevention of disease or to slow its onset and severity.

  • Human-Centred AI For Intelligent Healthcare

    Approaches and Technologies
    • 1st Edition
    • Mahmoud Hassaballah + 1 more
    • English
    Human-Centred AI For Intelligent Healthcare: Approaches and Technologies provides state-of-the-art AI technologies and healthcare tailored to human needs, highlighting the various ways AI is reshaping patient care, diagnostics, treatment modalities, and overall healthcare systems. From the intricacies of precision medicine to interventions in mental health, this reference provides a diverse array of AI applications. It addresses ethical considerations while emphasizing the transformative potential that AI holds for the healthcare industry. This reference is an essential companion for healthcare professionals, researchers, policymakers, technologists, and enthusiasts navigating the swiftly evolving landscape of AI in healthcare. Bridging a critical gap in literature, it offers a consolidated resource that not only explores the multifaceted applications of AI in healthcare but also underscores the importance of maintaining a human-centric approach in the integration of these technologies. With a focus on forecasting future trends and implications, this reference equips readers with the knowledge to stay at the forefront of the dynamic field of healthcare technology and empowers them to anticipate changes and adapt their strategies proactively in the face of evolving healthcare landscapes.

  • The Future of Health and Economic Resiliency in Africa

    • 1st Edition
    • Muhammad Pate + 1 more
    • English
    Grown out of a Lancet Commission to look at the future of health and economic resiliency of Africa, The Future of Health and Economic Resiliency takes a multidisciplinary approach across numerous sectors of analysis, central to Africa’s future well-being. This book serves as a comprehensive analysis of the current state of the continent and what actions can be taken to improve health and resiliency moving forward. While previous analysis has been done regionally within the continent (sub-Saharan Africa, for example) or by specific health needs (HIV or poverty, for example), this book will be the first to synthesize a cross sector approach pan-Africa. By describing the context and through actionable solutions for the future, this book sets the framework for a more resilient Africa and global future. Future of Health and Economic Resiliency is a collaboration of top African experts and practitioners in public health, health systems, economics, financing, nutrition, climate, youth representation, and the private sector.

  • Tissue Organization in Development

    • 1st Edition
    • Volume 171
    • English
    Tissue Organization in Development explores how cells coordinate, communicate, and arrange themselves to build functional tissues during embryonic and postnatal development. The book brings together current perspectives on the molecular, cellular, and mechanical principles that govern tissue patterning, morphogenesis, and structural organization across developing systems. Covering key topics such as cell fate specification, cell–cell interactions, extracellular matrix dynamics, polarity, migration, and tissue remodeling, it highlights how complex biological form emerges from coordinated developmental processes. This volume provides a valuable resource for researchers, students, and professionals interested in developmental biology, cell biology, and tissue formation.

  • Integrating AI in Psychological and Mental Health Care

    Techniques, Applications, and Ethical Considerations
    • 1st Edition
    • Sandeep Kautish + 4 more
    • English
    Integrating AI in Psychological and Mental Health Care: Techniques, Applications, and Ethical Considerations introduces key concepts and the historical evolution of AI, providing a foundation for understanding its applications in mental health. The content delves into various aspects of AI, including diagnostic tools, machine learning algorithms, and natural language processing, highlighting their roles in enhancing therapeutic outcomes and improving patient care. The discussion encompasses significant mental health conditions such as anxiety, depression, and severe psychological disorders, showcasing how AI technologies can assist in diagnosis, treatment planning, and monitoring. Ethical considerations and privacy issues are critically examined, ensuring a balanced perspective on the benefits and challenges associated with AI-driven interventions. Practical applications, such as virtual psychotherapists and AI-enhanced cognitive behavioral therapy illustrate real-world implementations and their impact on patient care. Additionally, case studies provide insights into successful AI applications in mental health settings, thus enhancing our understanding of potential advantages and obstacles.

  • Oil-Encapsulated Powders for Functional Foods

    Preparation and Practice
    • 1st Edition
    • Jian Zhong + 2 more
    • English
    Oil-Encapsulated Powders for Functional Foods: Preparation and Practice bridges the gap between fundamental research and industrial practice, emphasizing how encapsulation can enhance bioavailability, protect bioactives from environmental degradation, and improve sensory attributes. The book provides an in-depth guide for overcoming the scientific and technical challenges associated with stabilizing and delivering sensitive oils in food matrices, offering detailed insights into encapsulation science, advanced preparation techniques, and practical application strategies that are essential for creating effective, stable, and appealing functional foods. It covers core materials such as oils and wall substances, state-of-the-art encapsulation and drying methods, and robust characterization techniques.With real-world examples spanning formula foods, meat, dairy, and bakery products, this book is an essential resource for food scientists, nutritionists, and product developers dedicated to innovating health-oriented foods that meet modern consumer needs and promote overall wellness.

  • AI and Personalized Medicine in Cardiometabolic Disease

    Principles, Applications and Future Perspectives
    • 1st Edition
    • M. Salman Khan + 2 more
    • English
    AI and Personalized Medicine in Cardiometabolic Disease: Principles, Applications and Future Perspectives offers a comprehensive and timely exploration of how artificial intelligence (AI) is revolutionizing personalized care for cardiometabolic diseases. This authoritative volume bridges foundational AI concepts with cutting-edge translational applications, guiding clinicians, researchers, and data scientists through the integration of AI-driven tools in diagnosis, risk prediction, biomarker discovery, and tailored treatment strategies. Featuring real-world case studies, ethical and regulatory insights, and future-focused discussions on emerging technologies and equitable implementation, this book is an essential resource for healthcare professionals and scientists aiming to harness AI’s full potential to improve patient outcomes in cardiovascular and metabolic health.

  • Autophagy – Part D

    • 1st Edition
    • Volume 407
    • English
    Autophagy – Part D presents current methods and advances in the study of autophagy, covering experimental approaches, molecular mechanisms, and emerging applications across different biological and disease contexts. It serves as a useful resource for researchers investigating autophagy in cell biology, physiology, and translational research.

  • The Safety Aspects of Food Waste Valorization

    Maintaining Quality Assurance in Resource Recovery
    • 1st Edition
    • Sidonia Martínez Suárez + 1 more
    • English
    The Safety Aspects of Food Waste Valorization: Maintaining Quality Assurance in Resource Recovery highlights the importance of safe food waste practices and strategies to effectively transform waste into valuable resources. Co-edited by two female authors with many global, female contributors represented, the book looks at the environmental consequences of food waste and its impact on human health. It details the risks associated with the use of food waste, analyzes food safety in valorized agri-food by-products, with a focus on mycotoxins, and demonstrates how to minimize safety risks from a variety of industries, including date-palm industrialization, wine, produce, cattle, olive oil and dairy. Finally, the book provides practical business strategies for bioactive ingredients derived from food by-products and details the recovery of food waste from an environmental and economic perspective.

  • SGLT2 Inhibitors in Cardiovascular Diseases

    Mechanisms, Clinical Impact, and Future Directions
    • 1st Edition
    • Tong Liu
    • English
    SGLT2 Inhibitors in Cardiovascular Diseases: Mechanisms, Clinical Impact, and Future Directions reviews the impact of SGLT2 inhibitors on cardiovascular health in individuals with type 2 diabetes, chronic kidney disease, heart failure, and atherosclerosis. The book synthesizes preclinical and clinical evidence to highlight the cardiovascular benefits of these drugs, initially developed for hyperglycemia management. It details recent studies on SGLT2 inhibitors' effects on cognitive dysfunction, sudden death, ventricular arrhythmias, heart remodeling, and cancer risks in diabetic patients.In addition, it compares SGLT2 inhibitors with DPP4 inhibitors, emphasizing the efficacy of empagliflozin and dapagliflozin in reducing syncope and cardiovascular mortality, supported by trials like EMPA-REG OUTCOME and DECLARE-TIMI 58. Addressing a gap in literature, the book provides a comprehensive overview of SGLT2 inhibitors' cardiovascular benefits in high-risk populations, including atrial fibrillation and syncope. It offers valuable insights and recommendations for clinicians, researchers, and policymakers managing cardiovascular risk.

  • Mannose Binding Lectin Associated Serine Proteases

    Structure, Function and Therapeutic Implications
    • 1st Edition
    • Krishnan Hajela
    • English
    Mannose Binding Lectin Associated Serine Proteases: Structure, Function and Therapeutic Implications provides a comprehensive overview of MASP-1, MASP-2, and MASP-3, highlighting their roles in immune defense, disease mechanisms, and therapeutic intervention. This book covers the molecular structure and catalytic mechanisms of these key serine proteases, emphasizing their involvement in the lectin pathway of complement activation as well as their emerging functions in coagulation and bradykinin pathways. Chapters detail the biology of animal lectins and collections, classical and alternative complement pathways, and specific biochemical activities of MASP-1, MASP-2, and MASP-3.Readers will find in-depth discussions on the clinical significance of MASP gene polymorphisms and serum levels, and more. Special focus is given to the application of MASP-2 inhibitors in the management of complications such as hematopoietic stem-cell transplantation-asso... thrombotic microangiopathy (HSCT-TMA). This book is an essential resource for researchers in immunology, biochemistry, and molecular medicine, as well as clinicians seeking to advance their understanding of complement biology and the therapeutic potential of targeting the lectin pathway.

  • Biomechanics of the Heart

    From Model to Patient
    • 1st Edition
    • Patrick Clarysse + 3 more
    • English
    Biomechanics of the Heart: From Model to Patient provides readers with a comprehensive overview of the modeling and assessment of the heart’s biomechanics. The book addresses topics such as the physiology of normal and diseased hearts, cardiovascular imaging, modeling of myocardial tissue in the passive and active states, as well as state-of-the-art approaches for patient specific modeling of the heart’s mechanical function. This is all augmented by case studies and examples of exploitation of models for computer-aided diagnosis, treatment, and monitoring of heart diseases. Readers are introduced to modeling of the heart’s anatomical and muscular structure, a review of imaging techniques to analyze the geometry, content and dynamics of the heart, as well as an in-depth look at the biomechanical properties of normal and diseased hearts. Finally, chapters cover modeling cardiac passive and contractile mechanics, biomechanical finite element simulations of the heart, patient-specific modeling of the heart and circulatory system, as well as the exploitation of models for computer-aided diagnosis, treatment, and monitoring of heart diseases.

  • Neurosurgical Neuropsychology

    The Practical Application of Neuropsychology in the Neurosurgical Practice
    • 2nd Edition
    • Caleb M. Pearson + 2 more
    • English
    The second edition of Neurosurgical Neuropsychology: The Practical Application of Neuropsychology in the Neurosurgical Practice offers an in-depth review of the critical role neuropsychology plays in neurosurgical settings. This comprehensive resource covers essential preoperative techniques, including advanced functional neuroimaging methods such as fMRI and connectivity-based imaging, alongside traditional approaches like neurocognitive testing and the Wada procedure. This book highlights the significant contributions of neuropsychologists to the neurosurgical team, emphasizing their value in managing diverse patient populations, from candidates for Deep Brain Stimulation to those undergoing adult and pediatric epilepsy surgeries and neuro-oncology interventions. New chapters in this edition address contemporary topics such as the cognitive impact of epilepsy and epilepsy surgery, concussion, neuroplasticity, and the future role of artificial intelligence in neurosurgery. By updating existing content and incorporating fresh insights, this book serves as an essential guide for neurosurgeons, neuropsychologists, neuro-oncologists, epileptologists, and general neurologists who wish to enhance their understanding of neuropsychology's application in both preoperative and postoperative care.

  • Advances in Hepatorenal Syndrome Research

    Untangling Pathophysiology, Improving Diagnostic Strategies, and Leveraging Therapeutic Innovations
    • 1st Edition
    • Justin Belcher
    • English
    Advances in Hepatorenal Syndrome Research: Untangling Pathophysiology, Improving Diagnostic Strategies, and Therapeutic Innovations is a comprehensive review of the historical perspectives, prevalence, and prognosis of HRS, offering insights into its evolving clinical recognition and shifting paradigms of pathophysiology. Explore the multifaceted pathophysiology of HRS as experts navigate the complexities of cardiac dysfunction, inflammatory cytokines, and other modern understandings shaping the field. Explore differential diagnosis, uncovering alternative etiologies and current diagnostic criteria, while shedding light on biomarkers and novel diagnostic tests revolutionizing patient assessment. Contents will also guide readers through the utility of point-of-care ultrasound in intravascular volume assessment sets the stage for exploring medical therapy options, including vasoconstrictors and albumin usage. Written by a team of experts, this comprehensive reference highlights the intricate pathophysiology of hepatorenal syndrome while delivering the most up-to-date insights into diagnostic and therapeutic approaches. Historically overshadowed by grim prognoses, hepatorenal syndrome has undergone a renaissance of interest due to recent breakthroughs, revolutionizing treatment paradigms. Whether you're a seasoned practitioner or a burgeoning researcher immersing yourself in this dynamic field, this resource offers a thorough examination, encompassing novel diagnostic criteria, innovative biomarkers, and state-of-the-art treatments.

  • Translational Insights in Regenerative Medicine

    • 1st Edition
    • Volume 228
    • English
    Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Diagnosis and Management of Gastrointestinal Bleeding

    • 1st Edition
    • Xingshun Qi + 1 more
    • English
    Diagnosis and Management of Gastrointestinal Bleeding is a comprehensive reference addressing the latest advances in the diagnosis and management of gastrointestinal hemorrhage. This reference responds to the growing body of evidence accumulated in recent years, filling a critical gap where no recent comprehensive resource exists. It targets practicing gastroenterologists and researchers seeking current, evidence-based guidance. The content is systematically organized into 14 chapters covering epidemiology, causes, risk factors, diagnosis, and treatment modalities including medical, endoscopic, and vascular interventional approaches. Special chapters focus on management in children and the elderly. Each chapter is authored by leading experts, providing detailed insights into prevention, treatment, and prognostic assessment of gastrointestinal bleeding. Diagnosis and Management of Gastrointestinal Bleeding equips clinicians with practical knowledge to improve patient care and offers researchers a synthesis of innovative findings and future research directions. Its inclusion of color figures and visual aids enhances comprehension. This reference is an essential resource for those involved in the clinical and research aspects of gastrointestinal bleeding management.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 123
    • English
    Advances in Food and Nutrition Research provides the latest advances in the role of artificial intelligence in the precision nutrition and development of personalized foods, precision nutrition in autoimmune diseases, the need for vitamin D fortification in tropical regions, the health benefits of bioactive peptides, the factors affecting digestibility and glycemic index of rice, bio-based materials for intelligent sensing of food quality and safety, solid-state fermentation of cereal grains for modulating phenolic compounds, natural additives stabilized with nanoclays and the concomitant mycotoxin contamination in foods, especially on climate-related challenges for food safety.

  • Hysteroscopy and Female Infertility

    Diagnostic and Therapeutic Approaches in Clinical Practice
    • 1st Edition
    • Salvatore Giovanni Vitale
    • English
    Hysteroscopy and Female Infertility: Diagnostic and Therapeutic Approaches in Clinical Practice addresses the growing global challenge of infertility by focusing on the critical role of hysteroscopy in diagnosing and managing uterine factors that impair female fertility. The book fills a significant gap by providing an up-to-date, practical guide, including recent advances in hysteroscopic technology, such as AI-assisted diagnostics, to improve reproductive outcomes. Chapters cover a broad spectrum of uterine abnormalities such as polyps, fibroids, adhesions, Müllerian anomalies, endometritis, adenomyosis, and isthmocele, combining detailed diagnostic criteria, operative techniques, and evidence on reproductive outcomes.The inclusion of ultrasound correlations, decision-making algorithms, and QR-linked high-definition surgical videos enhances usability for both learning and clinical application. The book equips gynecologists, reproductive endocrinologists, and fertility specialists with a comprehensive, evidence-based resource designed to improve diagnostic precision and therapeutic efficacy.

  • Toxicology Disasters

    Causes and Consequences
    • 1st Edition
    • Sue Ford
    • English
    Toxicology Disasters: Cause and Consequences, a volume in the History of Toxicology and Environmental Health series, provides an historical overview of significant toxicological disasters which involved chemical exposure of humans, animals or the environment. The book documents the timeline of events and the legacy of the resulting exposure which occurred within a specific period of time, but with long lasting consequences. Case studies of toxicological incidents and a wide range of categories, including environmental, industrial, pharmaceutical, domestic and international are not only discussed from a historical perspective but also regarding their impacted toxicology, regulation and our current use of these chemicals.The book will help toxicologists, academics and students from environmental health and toxicology departments, environmental/occupa... health regulators, and industrial hygiene/safety personnel gain a better understanding of the arc of a toxicological disaster from its origins, root causes of the problem, and initial and long-term assessments and management.

  • Bioprospecting Native Microbiomes for Boosting Phytoremediation

    • 1st Edition
    • Vimal Chandra Pandey + 1 more
    • English
    Bioprospecting Native Microbiomes for Boosting Phytoremediation provides an inclusive overview of the use of metal-resistant native microbiomes for boosting the phytoremediation of polluted land for ecological and environmental restoration. The book offers a basic understanding of the principles and mechanisms of microbe-induced phytoremediation, microbiome resilience, adaptation to polluted lands, and metal-resistant native microbe-assisted phytotechnologies. It covers current trends, tools, and policies for the microbe-augmented remediation of an array of metals and metalloids. Other sections discuss key topics such as plant-metal-microbe interaction in polluted ecosystems, microbe-mediated phytoremediation for upgraded ecosystem services, and success stories on microbial-assisted phytoremediation.

  • Machine Learning and Urban Health

    Advancing Wellness through Data Analytics
    • 1st Edition
    • Deepak Kumar + 3 more
    • English
    Machine Learning and Urban Health: Advancing Wellness through Data Analytics explores how advanced data analytics and machine learning are reshaping the future of urban wellness. As cities worldwide evolve into highly interconnected, technology-driven spaces, new opportunities—and challenges—emerge for ensuring sustainable urban health. This timely volume addresses the critical question: how can we harness the power of data to improve health outcomes in complex urban environments? From predicting disease outbreaks to identifying vulnerable populations and optimizing resource allocation, this book highlights how machine learning is transforming the public health landscape.Drawing on real-world case studies and diverse datasets—including environmental sensors, population health indicators, and urban infrastructure metrics—the book provides actionable insights for researchers, policymakers, urban planners, and public health professionals. It emphasizes not only technical innovation but also the ethical and equitable use of health data to reduce disparities and enhance quality of life for all city residents.

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