Skip to main content
View Cart

Books in Life sciences

  • Social Determinants of Health in Surgery

    Research Methods and Clinical Review
    • 1st Edition
    • Steven A. Toms + 4 more
    • English
    Social Determinants of Health in Surgery: Research Methods and Clinical Review is a groundbreaking resource dedicated to examining the role of social determinants within surgical care. This book is designed for surgical trainees, healthcare providers, researchers, and policy administrators, offering a thorough exploration of how social factors impact surgical outcomes and practice. Featuring a detailed analysis of eleven key domains, it addresses the challenges and opportunities of integrating social determinants into surgical research and practice. The text provides essential guidance for those seeking to understand and improve patient outcomes through a broader, community-driven lens.In addition to its comprehensive coverage, the book delves into specialized topics such as big data analytics, ethical considerations, global health perspectives, pediatric surgical care, and clinical applications for research. It presents methodological guidance, including valuable tips and common pitfalls useful for readers at any stage of their surgical careers. The book also offers an in-depth review of social determinants research across ten major surgical specialties, highlighting significant trends, key studies, and current gaps in knowledge. Case studies and reflective interviews from experienced clinicians further enrich the reader’s understanding.

  • Advances in Noncoding RNA Diagnostics and Therapeutics in Immunity and Cancer

    • 1st Edition
    • Afsar Naqvi + 1 more
    • English
    Advances in Noncoding RNA Diagnostics and Therapeutics in Immunity and Cancer explores the critical role of noncoding RNAs in immune-mediated diseases and cancers, providing an essential resource on their diagnostic and therapeutic potential. The book contributes valuable insights into the pathobiology of noncoding RNAs and their application in various diseases, delving into the latest research on noncoding RNAs, including their mechanisms, interactions, and roles in disease. In addition, it examines how noncoding RNAs influence immune responses, inflammation, and cancer progression. With a focus on both diagnostic and therapeutic applications, this book highlights the potential of noncoding RNAs as biomarkers and therapeutic targets. Across comprehensive chapters, the book covers a wide range of topics, including the role of virus-encoded microRNAs in immune evasion, the therapeutic aspects of non-coding RNA in hepatocellular carcinoma, the impact of microRNAs in periodontal inflammation, and the involvement of miRNAs and lncRNAs in regulating the tumor microenvironment in HCC. Other chapters explore the functions and clinical value of tumor-derived exosomes and miRNAs in cancer immune response, the interaction of noncoding RNA in cancer metastasis, and a panorama of non‐coding RNA in prostate cancer. This book is an invaluable resource for basic science researchers in the noncoding RNA field, cancer biologists, immunologists and RNA biologists interested in the latest advancements in noncoding RNA research.

  • MRI of Brain Physiology

    Novel Methods and Clinical Applications
    • 1st Edition
    • Audrey P. Fan + 1 more
    • English
    MRI of Brain Physiology: Novel MRI Methods and Clinical Applications delves into the intricate world of brain physiology, focusing on the latest magnetic resonance imaging (MRI) methods and their clinical applications. Designed for biomedical engineers, technologists, radiologists, neurologists, neurosurgeons, and clinical researchers, this resource bridges the gap between advanced imaging techniques and practical clinical use. It covers a wide spectrum of cerebral physiology, from microvascular and macrovascular dynamics to cerebrovascular reserve, neurovascular coupling, and cerebrospinal fluid pathways. Each of the core chapters has a tripartite structure: physiology (concepts of the physiological processes), imaging techniques, and clinical applications. Readers will find detailed discussions on emerging MRI methods, including dynamic contrast, arterial spin labeling, and quantitative BOLD models. The book also addresses the functional impact of physiological changes on tissue microstructure and integrity, offering insights into multiparametric relaxation mapping and quantitative susceptibility mapping. Uniquely, this book gives a comparative approach to different brain physiological MRI methods, highlighting their strengths, limitations, and reliability.

  • Medicinal Plant Biotechnology for Ameliorated Secondary Metabolite Production

    • 1st Edition
    • Saikat Gantait + 3 more
    • English
    Medicinal Plant Biotechnology for Ameliorated Secondary Metabolite Production offers important insights into the latest approaches for enhancing and optimizing the beneficial aspects of these important plants. It encompasses micropropagation, cell-culture methodologies, genetic transformation, genome editing, analysis of secondary metabolites with chromatograph, and the preservation of plant genetic resources. Biological technologies encompass a broad range of techniques that can be used in different fields of environmental science, agriculture and the development of medicines.The potential benefits include enhanced plant protection, genetic engineering, tissue culture, bioprocessing, and genome editing for enhancing secondary metabolites. In addition to their use in treating conditions, medicinal plants contribute to biodiversity, conservation, and economic development. They are valued for their secondary metabolites and bioactive compounds. This book in the Medicinal and Industrial Plants and Products series presents the latest information across a broad spectrum of plant biotechnology, advancing understanding of approaches to ensure plant health improvement.

  • Moving Toward Nonanimal Approaches in Medical Research and Testing

    • 1st Edition
    • Gail A. Van Norman + 1 more
    • English
    Moving Toward Nonanimal Approaches in Medical Research and Testing pioneers a single-source guide for researchers regarding nonanimal research tools and methodologies and their many advantages and applications in place of animals. This book is presented in three parts: historical, ethical, legislative, and scientific contexts on the need to shift away from animal-based research and testing; the latest advances in nonanimal tools and methods for biomedical research and testing of human therapeutics and other compounds, including microphysiological systems, bioprinting, biobanks, and artificial intelligence; and achieving a practical shift toward these powerful approaches, including advocacy for legal, regulatory, and policy change, securing funding for nonanimal studies, and how to overcome bias against nonanimal methods. This book, primarily directed to researchers in biomedicine, human medical therapeutics, and toxicology, will also appeal to researchers in industry, providing overview and insights about the latest applications of nonanimal research tools and methods for product development and testing. Clinicians who wish to understand the reliability of testing therapeutics with nonanimal versus animal methods, as well as advocacy groups seeking an up-to-date understanding of ethical, economic, political, and scientific considerations in moving toward nonanimal approaches, will also find significant value in this text. Finally, legislators and those involved in regulatory review and oversight will benefit from this single comprehensive source for developing a basic understanding of nonanimal research and human safety.

  • Aquatic Biodiversity

    Theories, Approaches, and Future Directions
    • 1st Edition
    • Bryan L Brown + 1 more
    • English
    Aquatic Biodiversity: Theories, Approaches, and Future Directions reviews the development of metacommunity ecology theory in aquatic systems. The book explores aquatic dispersal as a driver of community biodiversity, patterns, and processes. Considered a relatively new field, metacommunity ecology created a paradigm shift in the field of aquatic ecology by developing a novel, network-based theory that differences in connectivity throughout aquatic systems lead to predictable variations in the mechanisms of assembly for lentic and lotic communities. This book collates the cutting edge conceptual, theoretical, and empirical advancements of the field and its contributions to invasive species management, biomonitoring, and stream restoration.Written and edited by many of the key researchers contributing to the development of the field, this book is systematically structured for easy accessibility by diverse audiences. Introductory sections discuss the importance of spatial structure, dispersal dynamics in aquatic systems, the effects of disturbances, and eco-evolutionary dynamics. Latter chapters apply these theories by describing field experiments in lentic and lotic systems and highlighting the field's applications to stream restoration, invasive species monitoring, urban ecosystem management, and biomonitoring at varying spatial scales.As advancements and refinements to the field of metacommunity ecology develop, Aquatic Biodiversity presents the first compendium establishing its foundational theories and their applications in aquatic ecology. For this reason, it is an indispensable resource for students, researchers, community ecologists, and aquatic resource managers.

  • Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics

    • 1st Edition
    • Lara Scheherazade Milane + 1 more
    • English
    Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics delves into the complex world of intercellular communication biology and its implications on therapeutics. This book covers all areas of intercellular communication and therapeutics in development for different forms of communication, including their role in diseases such as cancer, neurological disorders, metabolic diseases, and inflammatory/immune diseases. Sections provide an introduction, biological targets, challenges, and approaches to overcoming biological barriers and the significance of contact points and mechanisms of internalization. Specifics of tunneling nanotubes, extracellular vesicles, and the immune and non-immune interface in various diseases are covered. Furthermore, the book explores the crosstalk of different forms of intercellular communication and the implications of mitochondrial exchange in the four primary pathological areas. This is an essential resource for researchers, students, and professionals in the field of drug development and delivery. By connecting the dots between extracellular vesicles, tunneling nanotubes, and cell-cell junctions, this book serves as a foundation for further advancements in the science of intercellular communication and it's applications to new drug discovery and delivery.

  • Glial Mechanisms in Sleep and Circadian Biology

    • 1st Edition
    • Marcos G. Frank
    • English
    Glial Mechanisms in Sleep and Circadian Biology presents a comprehensive and up-to-date discussion of the role of glial cells in numerous, often unexpected, aspects of sleep. It seamlessly links glial cell activity to the multi-system processes that affect sleep. Experts in the field discuss how glial cells influence the sleep-wake cycle, the accumulation and discharge of sleep drive, the timing of sleep and wake across the 24-hour day, and how glial cells may govern important sleep functions (e.g., brain plasticity and metabolism). This is a book that could well change scientists’ and practitioners’ traditional beliefs about the factors underlying sleep.Users will find the book's content at the forefront of one of the hottest topics in basic sleep research. Over the last decade, scientists have made breakthrough discoveries revealing that sleep is not only a product of neurons, but of neuronal-glial interactions.

  • A Modern Atlas for Implantable Devices of the Spine, Brain, and Nerve

    For Pain, Movement Disorders, and Nerve Dysfunction
    • 1st Edition
    • Timothy R. Deer + 1 more
    • English
    A Modern Atlas for Implantable Devices of the Spine, Brain, and Nerve: For Pain, Movement Disorders, and Nerve Dysfunction is an essential resource for healthcare professionals and researchers working in neuromodulation. This groundbreaking text focuses on the latest advancements in implantable technologies, exploring innovative techniques, frequencies, and neural targets that have revolutionized patient care. Covering a diverse range of conditions related to pain, movement disorders, and nerve dysfunction, the atlas provides a detailed overview of spinal, brain, and peripheral nerve procedures. It combines anatomical insights with clinical best practices to help professionals achieve enhanced outcomes in complex medical scenarios.In addition to introducing cutting-edge devices, the book delves into procedures like spinal cord stimulation and dorsal root ganglion modulation, offering a roadmap for navigating intricate anatomical and procedural landscapes. The atlas includes valuable sections on sacral nerve modulation and peripheral nerve stimulation, ensuring comprehensive coverage of neuromodulation's expanding possibilities. By bridging theoretical knowledge with practical application, this resource equips practitioners with the tools needed to address diverse patient challenges effectively.

  • Cryo-EM Methods and Management

    • 1st Edition
    • Edward T. Eng + 2 more
    • English
    Cryo-EM Methods and Management provides a detailed introduction to the latest advances of cryo-EM, from technical innovations to the logistical challenges of maintaining a modern cryo-EM facility. The book consists of four parts, beginning with an overview of cryo-EM. It then moves on to discuss Cryo-EM workflows, with chapters focusing on sample handling and preparation, data collection and hardware, and data procession and visualization. The third part centers on aspects of cryo-EM infrastructure and community building, considering facility set-up and management, monitoring facility performance, instrumentation monitoring , data sharing and standards, and training and development standards. The book then closes with a section looking towards future prospects for cryo-EM. This is an ideal reference for cryo-EM facility and lab managers, providing guidance to the often-overlooked aspect of facility building and management. Additionally researchers working with cryo-EM across molecular biology, structural biology, cell biology and biochemistry will benefit from this book.

Related subjects