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Elsevier

Books in Life sciences

  • Progress in Motor Control

    Crossroads between Neurophysiology and Applications
    • 1st Edition
    • Mark L. Latash + 4 more
    • English
    "Progress in Motor Control: Crossroads between Neurophysiology and Applications" offers an in-depth look at the evolving field of motor control, synthesizing the latest research. This volume explores the complex roles of the central nervous system in movement, featuring contributions from leading experts who use approaches ranging from basic physical principles to advanced control theory. It addresses applied aspects of motor control, focusing on recovery strategies for functional movements in patients with spinal cord injuries, subcortical disorders, and strokes. Organized into five sections, the book covers theoretical advances, neurophysiological mechanisms, motor learning, neural plasticity, and motor disorders, including topics like neural population dynamics and vestibulospinal reflexes. The final sections highlight strategies for improving recovery after neurological events. This resource bridges foundational research and clinical application, making it invaluable for researchers, clinicians, and students in motor control, neuroscience and rehabilitation.Divid... into five comprehensive parts, the book covers theoretical advances, neurophysiological mechanisms, motor learning, neural plasticity, and motor disorders, including essential topics like neural population dynamics and the dual role of vestibulospinal reflexes. Final sections highlight practical strategies for improving recovery outcomes following neurological events.

  • Advances in Hepatorenal Syndrome Research

    Untangling Pathophysiology, Improving Diagnostic Strategies, and Leveraging Therapeutic Innovations
    • 1st Edition
    • Justin Belcher
    • English
    Advances in Hepatorenal Syndrome Research: Untangling Pathophysiology, Improving Diagnostic Strategies, and Therapeutic Innovations is a comprehensive review of the historical perspectives, prevalence, and prognosis of HRS, offering insights into its evolving clinical recognition and shifting paradigms of pathophysiology. Explore the multifaceted pathophysiology of HRS as experts navigate the complexities of cardiac dysfunction, inflammatory cytokines, and other modern understandings shaping the field. Explore differential diagnosis, uncovering alternative etiologies and current diagnostic criteria, while shedding light on biomarkers and novel diagnostic tests revolutionizing patient assessment. Contents will also guide readers through the utility of point-of-care ultrasound in intravascular volume assessment sets the stage for exploring medical therapy options, including vasoconstrictors and albumin usage. Written by a team of experts, this comprehensive reference highlights the intricate pathophysiology of hepatorenal syndrome while delivering the most up-to-date insights into diagnostic and therapeutic approaches. Historically overshadowed by grim prognoses, hepatorenal syndrome has undergone a renaissance of interest due to recent breakthroughs, revolutionizing treatment paradigms. Whether you're a seasoned practitioner or a burgeoning researcher immersing yourself in this dynamic field, this resource offers a thorough examination, encompassing novel diagnostic criteria, innovative biomarkers, and state-of-the-art treatments.

  • Biosimilars and Biologics in Cancer Treatment

    An Era in Therapeutic Strategies
    • 1st Edition
    • Kuttiappan Anitha + 2 more
    • English
    Biosimilars and Biologics in Cancer Therapy: An Era in Therapeutic Strategies addresses challenges and opportunities in biosimilars and biologics, integrating the latest evidence, regulatory landscapes, economic implications, and strategies to enhance cancer management. The book aims to create an all-inclusive educational resource, bridge the gap between research and clinical practice, and inspire future research in oncology. It provides a comprehensive examination of cancer therapeutics, starting with an introduction to biologics and biosimilars, their historical development, and foundational principles. Sections explain mechanisms of action, drug development processes, regulatory landscapes, and clinical applications through case studies. Emerging therapeutic strategies, including combination therapies and personalized medicine, are also covered. This book benefits researchers, oncologists, pharmacologists, pathologists, and other healthcare professionals by offering up-to-date insights into the clinical aspects of biological medications and their biosimilars. Contributions from global experts ensure readers gain the latest advancements and practical guidance on integrating these therapies into clinical practice and research.

  • Agricultural Pollination

    The Role of Beneficial Insects in Food Security and Sustainability
    • 1st Edition
    • Habib Ali
    • English
    Agricultural Pollination: The Role of Beneficial Insects in Food Security and Sustainability delves into the intricate relationship between farming and pollinators, as well as other beneficial insects, examining the ways in which their ecological roles can improve crop health and yield, ultimately bolstering food security without environmentally harmful chemical interventions. The book begins with coverage of foundational topics, such as types of key pollinators and their behaviors, and moves into more practical topics, such as creating pollinator-friendly landscapes and emerging technologies in pollination services.Taking a multidisciplinary approach, the book also covers conservation strategies, economic impacts of pollinators, policy recommendations, and community engagement. This timely reference will offer invaluable insights for researchers, students, agricultural industry professionals, and policymakers alike, contributing to the advancement of environmentally-frie... and economically viable agricultural practices.

  • Microbial Exopolysaccharides

    An Integrated Approach to Green Applications
    • 1st Edition
    • Onkar Nath Tiwari + 2 more
    • English
    Microbial Exopolysaccharides: An Integrated Approach to Green Applications provides a comprehensive overview of natural exopolysaccharides (EPS) obtained from different microbial species and marine resources. Featuring contributions by an interdisciplinary group of experts in academia, research, and industry, this book offers a detailed introduction and exploration of natural microbial exopolysaccharides. It offers detailed discussions on topics such as the extraction and characterization of EPS, their role in health-promoting formulations and probiotic potential, their utilization in therapeutics, their use in food technologies and packaging, and their impact in the environmental and medical sectors.The book offers in-depth insights into the principles of EPS and their wide range of applications as sustainable solutions to challenges in the food, health, environmental, and biotechnology sectors.With a focus on green technology and sustainable practices, this book offers cost-effective utilization of natural EPS, their application in diverse sectors, and serves as an informative resource for those interested in the innovative application of natural bio-macromolecules.

  • The Honey Bee and Climate Change

    • 1st Edition
    • Gloria DeGrandi-Hoffman
    • English
    A honey bee colony is a community of interacting organisms continually adjusting their behaviors, both individually and collectively, in response to even the subtlest changes in the environment. It’s only logical then, that the more significant changes and stressors due to climate change will push the colony to its limits, disrupting the delicate balance of the hive and threatening the survival of the colony. Honey Bees and Climate Change is the first and only book to examine the responses of honey bees to climate change and the threat it poses to their ability to thrive and survive. Drawing on systems science and the central theme that all outcomes are products of an interconnected system, the book will address how climate change is affecting honey bee nutrition, growth, and overwinter survival, which in turn threaten commercial beekeeping and crop production. Impacts on other pollinators will be touched on as well. Finally, potential mitigating strategies, key areas of action, and the future outlook will be covered.Written by a leading scientist with over 40 years of experience studying honey bee physiology, nutrition, colony survival, and the impact of climate change on the colony, Honey Bees and Climate Change is crucial reading for students and researchers studying honey bees, especially those with an interest in the impacts of climate change on pollinators. The inclusion of key terms and definitions as well as case studies make this work an excellent supplementary text for courses on honey bee biology, apiculture, pollinator conservation, or climate change ecology.

  • Mastering Supraventricular Tachycardia Diagnostics in the Electrophysiology Lab

    • 1st Edition
    • Konstantinos P. Letsas + 1 more
    • English
    Mastering Supraventricular Tachycardia Diagnostics in the Electrophysiology Lab is dedicated to the diagnostics of supraventricular tachycardias (SVTs) for the electrophysiologist. The book is organized as a flowchart, allowing readers to accurately determine the proper next steps to take when managing patients' presenting symptoms. Its diagnostic approach starts with the evaluation of the 12-lead ECG, continues with electrophysiological observations and maneuvers, and ends with three-dimensional mapping techniques and real-life cases. Chapters are concise and focus on demonstrating the background of each maneuver in a simple manner by using sketches and electrograms from the lab.Each chapter contains a brief summary of when to use a maneuver, how to perform it, what to expect as responses to the maneuver, and interpretation of possible responses. Final chapters discuss real-life cases where the aforementioned diagnostic approaches are adapted to conditions that may not be ideal (for example, non sustained tachycardias). The book provides a start to finish explication of how to comprehend, diagnose, and manage all aspects of SVT.

  • Gallin and Ognibene's Principles and Practice of Clinical Research

    • 5th Edition
    • John I. Gallin + 2 more
    • English
    Gallin and Ognibene’s Principles and Practice of Clinical Research, Fifth Edition provides the definitive text on clinical research as written by internationally recognized experts from the National Institutes of Health, the US Food and Drug Administration, academia, and global researchers. This new edition contains more than 30 new authors and 9 new chapters. Topics covered emphasize the role of informatics in clinical research, incorporating clinical outcome assessment into endpoints for decision-making, inclusion of diverse and vulnerable research subjects, patient advocacy groups, rare disease research, preparing research for pandemics, public health emergencies, research opportunities for surgeons, and content on preclinical animal studies.For the international researcher, two new chapters detail international clinical research experiences in South Africa, India, and Pakistan. As with the previous edition, the new release provides readers with summary questions and answers after each chapter.

  • Advanced Cancer Therapeutics

    Strategies and Technologies for Targeted Drug Delivery
    • 1st Edition
    • Manish Kumar + 2 more
    • English
    Advanced Cancer Therapeutics: Strategies and Technologies for Targeted Drug Delivery explores the heterogeneity of tumors and microenvironmental factors that influence cancer treatment and contribute to drug resistance. The book discusses critical elements such as tumor stroma, vasculature, pH, hypoxia, and enzymatic activity that impact therapeutic efficacy. Sections cover advanced drug formulations, including supramolecular systems, metal-organic frameworks, and nanomedicine, focusing on their roles in selective drug delivery for early detection, diagnosis, and treatment of various cancers. In addition, it reviews the current status and future perspectives of these formulations, highlighting their potential to enhance therapeutic outcomes while minimizing side effects.Readers will also find discussions on the limitations of nanocarriers, along with regulatory and ethical considerations related to anticancer formulations. This resource is invaluable for researchers, clinicians, and students, offering insights into the latest advancements in drug delivery systems.

  • Mineral Nutrients to Mitigate Abiotic Stress in Crops

    • 1st Edition
    • Azamal Husen
    • English
    Mineral Nutrients to Mitigate Abiotic Stress in Crops offers a clear and timely examination of the physiological and biochemical dynamics that govern how plants endure increasingly unpredictable growing conditions. The volume begins by outlining the fundamental principles that shape a crop’s capacity to acquire, distribute, and utilize nutrients, and then considers how these processes influence its survival and productivity when confronting drought, salinity, heat, or nutrient-induced stress. Across the chapters, contributors show how nutrient availability guides defense mechanisms—from maintaining cellular stability and enzymatic function to modulating antioxidant potential, osmotic adjustment, and stress-related signaling—and how intensifying environmental pressures reorder metabolic priorities, redirect root behaviour, and reallocate resources at the whole-plant level.Building on this foundation and proceeding in an intentionally structured sequence, this book integrates applied approaches encompassing soil and fertilizer systems, nutrient biofortification, and the breeding of nutrient-efficient cultivars. By integrating established science with emerging insights, it delivers a coherent, forward-looking framework for interpreting plant resilience and for implementing adaptive strategies that underpin effective responses in diverse cultivation contexts, thereby strategically equipping researchers and practitioners to navigate the increasingly complex challenges facing modern agriculture.

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