
Fundamentals and Applications of Nanobiotechnology
- 1st Edition - December 1, 2025
- Author: Basanta Kumara Behera
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 4 0 5 5 5 - 6
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 4 0 5 5 6 - 3
Fundamentals and Applications of Nanobiotechnology offers a discussion on the integration of nanotechnology and biotechnology research and the industrial potential of nanobi… Read more

Fundamentals and Applications of Nanobiotechnology offers a discussion on the integration of nanotechnology and biotechnology research and the industrial potential of nanobiotechnology across diverse sectors such as medical sciences, agriculture, cosmetics, and food sciences. Covering a wide array of topics, this book provides a fundamental overview and practical insights into nanobiotechnology. Topics include the significance of biological nanoparticles, the different types of bionanoparticles, their structural interactions with biological systems, mechanisms of nanoparticle entry, and their applications in drug development, food sciences, agriculture, and cosmetics. Additionally, it addresses the challenges, perspectives, and ethical considerations surrounding nanobiotechnology, offering a holistic view of the field's potential impact on society and the environment. Through detailed discussions and practical insights, this book serves as resource for researchers, industry professionals, and students seeking to navigate the complexities of designing, commercializing, and utilizing nanobiotechnology-based products across various industries.
- Offers an introduction to the brief history and fundamentals of nanobiotechnology
- Discusses the structure, interaction, and mechanisms of entry of nanoparticles in biological systems
- Examines specific types of bionanoparticles and offers practical insights into product development, method of production, and commercial applications
- Explores the challenges of nanobiotechnology which includes legal aspect of implementation, ethical considerations, environmental regulation, and responsible development
Scientists, researchers, and graduate students, postgraduate researchers in biotechnology, nanoscience, life sciences seeking a foundational knowledge of nanobiotechnology and its potential applications; R&D scientists involved in product development, quality assessment, and improvement
1. Fundamentals of Nanotechnology and Biotechnology
1.1 Brief history of nanotechnology
1.2 Nanobiotechnology concept, vision, and scope
1.3 Significance of biological nanoparticles
1.4 Characterization of nanobiomolecules
1.5 Integration of nanoparticles with biomolecules
2. Different Types of Bionanoparticles
2.1 Method of production of bionanoparticles
2.2. Biopolymer based nanoparticles
2.3 Lipid-based nanoparticles
2.4 Inorganic based bionanoparticles
2.5. Virus-based nanoparticles
2.6 Protocols for bionanoparticles development
3. Structure and Interaction of Nanoparticles with Biological Systems
3.1 Biomolecules versus nanoparticles
3.2 Structural variation in nanobiomolecules
3.3 Nanoparticle biomolecule conjugate
3.4 Surface modification of nanobioparticles
3.5 Structure analysis of nanoparticles
4. Mechanism of Entry of Nanoparticles in Biological Systems
4.1 Effect of microenvironment
4.2 Interaction with cell membrane
4.3 Phagocytosis
4.4 Clathrin-mediated entry
4.5 Caveolae dependent endocytosis
4.6 Microphagocytosis
4.7 Effect of surface functionality
4.8 Intracellular traffic
5. Cytotoxicity Assay of Nanoparticles in Human Cells
5.1 In vivo toxicity assays (cell-based assay)
5.2 In vitro toxicity assays (cell cultured based)
5.3 Metallic nanoparticle toxicity
5.3.1 Gold nanoparticle
5.3.2 Silver nanoparticles
5.3.3 TiO2 nanoparticles
5.3.4 Carbon nanotubes
5.4 Ethic Issues
6. Nanotechnology in Biological Drug Upgradation
6.1 Nanoparticle-based drug delivery
6.2 Enhanced diagnostic using nanobiosensors
6.3 Nanoparticle-assisted tissue engineering
6.4 Regenerative medicine with nanomaterials
6.5 Nanotechnology-based vaccines for improved immunity
6.6 Sustainable and targeted drug delivery
7. Application of Nanobiotechnology in Food Sciences
7.1 Food Safety
7.1.1 Pathogen detection
7.1.2 Early toxin detection
7.1.3 Allergen detection
7.1.4 Biofilm upgradation
7.2 Food packaging
7.2.1 Packaging paper quality improvement
7.2.2 Improve packaging safety
7.2.3 Biosensor for packaging quality detection
7.3 Food Processing
7.3.1 Nanoadditives
7.3.2 Nanonutraceuticals
7.3.3 Nanoencapsulation
8. Applications of Nanobiotechnology in Agriculture
8.1 Biological pesticides versus chemical pesticide
8.1.1 Biological fungicide
8.1.2 Biological insecticides
8.1.3 Biological algaecide
8.2 Bio fertilizer
8.2.1 Heterotrophic bacteria
8.2.2 Phototrophic bacteria
8.2.3 Fungi
8.2.4 Nanoparticles used in bio- fertilizer
8.3 Nanotechnology for crop improvement
8.4 Nanotechnology based precision farming
8.5 Nanotechnology based crop stress tolerance
9. Nanotechnology for Cosmetic Upgradation
9.1 Nanomaterials used in cosmetics
9.2 Biological materials used in cosmetics
9.3 Nanotechnology in cosmetics - pros and cons
9.4 Global bio-based cosmetic market
10. Challenges, Perspectives, and Ethical Issues of Nanobiotechnology
10.1 Challenges for nanotechnology
10.2 Legal aspects in implementation
10.2 Ethical considerations of human augmentation
10.3 Environmental regulation and responsible development
10.4 Public awareness and risk communication
10.5 Global market
1.1 Brief history of nanotechnology
1.2 Nanobiotechnology concept, vision, and scope
1.3 Significance of biological nanoparticles
1.4 Characterization of nanobiomolecules
1.5 Integration of nanoparticles with biomolecules
2. Different Types of Bionanoparticles
2.1 Method of production of bionanoparticles
2.2. Biopolymer based nanoparticles
2.3 Lipid-based nanoparticles
2.4 Inorganic based bionanoparticles
2.5. Virus-based nanoparticles
2.6 Protocols for bionanoparticles development
3. Structure and Interaction of Nanoparticles with Biological Systems
3.1 Biomolecules versus nanoparticles
3.2 Structural variation in nanobiomolecules
3.3 Nanoparticle biomolecule conjugate
3.4 Surface modification of nanobioparticles
3.5 Structure analysis of nanoparticles
4. Mechanism of Entry of Nanoparticles in Biological Systems
4.1 Effect of microenvironment
4.2 Interaction with cell membrane
4.3 Phagocytosis
4.4 Clathrin-mediated entry
4.5 Caveolae dependent endocytosis
4.6 Microphagocytosis
4.7 Effect of surface functionality
4.8 Intracellular traffic
5. Cytotoxicity Assay of Nanoparticles in Human Cells
5.1 In vivo toxicity assays (cell-based assay)
5.2 In vitro toxicity assays (cell cultured based)
5.3 Metallic nanoparticle toxicity
5.3.1 Gold nanoparticle
5.3.2 Silver nanoparticles
5.3.3 TiO2 nanoparticles
5.3.4 Carbon nanotubes
5.4 Ethic Issues
6. Nanotechnology in Biological Drug Upgradation
6.1 Nanoparticle-based drug delivery
6.2 Enhanced diagnostic using nanobiosensors
6.3 Nanoparticle-assisted tissue engineering
6.4 Regenerative medicine with nanomaterials
6.5 Nanotechnology-based vaccines for improved immunity
6.6 Sustainable and targeted drug delivery
7. Application of Nanobiotechnology in Food Sciences
7.1 Food Safety
7.1.1 Pathogen detection
7.1.2 Early toxin detection
7.1.3 Allergen detection
7.1.4 Biofilm upgradation
7.2 Food packaging
7.2.1 Packaging paper quality improvement
7.2.2 Improve packaging safety
7.2.3 Biosensor for packaging quality detection
7.3 Food Processing
7.3.1 Nanoadditives
7.3.2 Nanonutraceuticals
7.3.3 Nanoencapsulation
8. Applications of Nanobiotechnology in Agriculture
8.1 Biological pesticides versus chemical pesticide
8.1.1 Biological fungicide
8.1.2 Biological insecticides
8.1.3 Biological algaecide
8.2 Bio fertilizer
8.2.1 Heterotrophic bacteria
8.2.2 Phototrophic bacteria
8.2.3 Fungi
8.2.4 Nanoparticles used in bio- fertilizer
8.3 Nanotechnology for crop improvement
8.4 Nanotechnology based precision farming
8.5 Nanotechnology based crop stress tolerance
9. Nanotechnology for Cosmetic Upgradation
9.1 Nanomaterials used in cosmetics
9.2 Biological materials used in cosmetics
9.3 Nanotechnology in cosmetics - pros and cons
9.4 Global bio-based cosmetic market
10. Challenges, Perspectives, and Ethical Issues of Nanobiotechnology
10.1 Challenges for nanotechnology
10.2 Legal aspects in implementation
10.2 Ethical considerations of human augmentation
10.3 Environmental regulation and responsible development
10.4 Public awareness and risk communication
10.5 Global market
- Edition: 1
- Published: December 1, 2025
- Language: English
BB
Basanta Kumara Behera
Dr. Basanta Kumara Behera was a Professor of Biotechnology at three distinguished Indian universities, where he taught and conducted research at the post-graduate level on medical biotechnology, biopharmaceutical, microbial process development, drug designing, bio-energy management, and biomass processing technology since 1978. In 2009, he joined an MNC company as an advisor for specialty chemicals production and drug design through microbial process technology. He is associated with national and international companies as a technical advisor to produce biopharmaceuticals under cGMP norms. Dr. Behera has authored and edited books with various publishers worldwide.
Affiliations and expertise
Former Director, Advanced Center for Biotechnology, Maharshi Dayanand University, Rohtak, Haryana, India