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Books in Life sciences

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  • Therapeutic Strategies to Overcome ALK Resistance in Cancer

    • 1st Edition
    • Volume 13
    • Luc Friboulet
    • English
    Therapeutic Strategies to Overcome ALK Resistance in Cancer, Volume 13, presents current strategies to improve and prolong clinical benefit in ALK driven cancers. Most patients with ALK-driven cancer are sensitive to tyrosine kinase inhibitor (TKI) therapy, but resistance invariably develops. This book discusses topics such as structure and function of ALK, ALK rearranged lung cancer, resistance mechanisms to ALK TKI tumors, and novel therapeutic strategies to enhance crizotinib anti-tumor efficacy in ALCL. Additionally, it encompasses information on drug combinations to enhance ALK TKI anti-tumor efficacy in neuroblastoma and future perspectives in the field. This book is a valuable resource for cancer researchers, clinicians and several members of biomedical field who need to understand more about how to fight ALK resistance in cancer treatment.

  • Crop Physiology Case Histories for Major Crops

    • 1st Edition
    • Victor O. Sadras + 1 more
    • English
    Crop Physiology: Case Histories of Major Crops updates the physiology of broad-acre crops with a focus on the genetic, environmental and management drivers of development, capture and efficiency in the use of radiation, water and nutrients, the formation of yield and aspects of quality. These physiological process are presented in a double context of challenges and solutions. The challenges to increase plant-based food, fodder, fiber and energy against the backdrop of population increase, climate change, dietary choices and declining public funding for research and development in agriculture are unprecedented and urgent. The proximal technological solutions to these challenges are genetic improvement and agronomy. Hence, the premise of the book is that crop physiology is most valuable when it engages meaningfully with breeding and agronomy. With contributions from 92 leading scientists from around the world, each chapter deals with a crop: maize, rice, wheat, barley, sorghum and oat; quinoa; soybean, field pea, chickpea, peanut, common bean, lentil, lupin and faba bean; sunflower and canola; potato, cassava, sugar beet and sugarcane; and cotton.

  • Neuro-Oncology for the Clinical Neurologist

    • 1st Edition
    • Roy E. Strowd
    • English
    In the growing field of neuro-oncology, the past few years have witnessed rapid advances in tumor classification, treatment modalities, and the role of neurologists and neuro-oncologists. Neuro-Oncology for the Clinical Neurologist is a first-of-its-kind resource that focuses on patient-clinical scenarios relevant to the practicing neurologist—bringing you up to date with everything from basic principles and neuro-oncology imaging consults to neurologic complications of radiation, systemic, and immune-based therapies, and much more.

  • Neuroendocrine Regulation of Animal Vocalization

    Mechanisms and Anthropogenic Factors in Animal Communication
    • 1st Edition
    • Cheryl S. Rosenfeld + 1 more
    • English
    Neuroendocrine Regulation of Animal Vocalization: Mechanisms and Anthropogenic Factors in Animal Communication examines the underpinning neuroendocrine (NE) mechanisms that drive animal communication across taxa. Written by international subject experts, the book focuses on the importance of animal communication in survival and reproduction at an individual and species level, and the impact that increased production and accumulation of endocrine-disrupting chemicals (EDCs) can have on these regulatory processes. This book discusses sound production, perception, processing, and response across a range of animals. This includes insects, fish, bats, birds, nonhuman primates, infant humans, and many others. Some chapters analyze how neuroactive substances, endocrine control, and chemical pollution affect the physiology of the animal’s perceptive and sound-producing organs, as well as their auditory and vocal receptors and pathways. Other chapters address the recent approaches governments have taken to protect against the endocrine disruption of animal (vocal) behaviors. The book is a valuable resource for researchers and advanced students seeking first-rate material on neuroendocrinologica... effects on animal behavior and communication.

  • Enzyme Active Sites and their Reaction Mechanisms

    • 1st Edition
    • Harry Morrison
    • English
    Enzyme Active Sites and their Reaction Mechanisms provides a one-stop reference on how enzymes "work." Here, Dr. Harry Morrison, PhD and Professor Emeritus at Purdue University, provides a detailed overview of the origin and function of forty enzymes, the chemical details of their active sites, their mechanisms of action, and associated cofactors. The enzymes featured highlight a step forward, along with possible areas of application, thus supporting new research in academic and industrial labs. Each chapter is written in a clear format, including a brief summary of enzyme function and structure, a detailed description of their mechanisms of action and associated co-factors.

  • Olives and Olive Oil in Health and Disease Prevention

    • 2nd Edition
    • Victor R. Preedy + 1 more
    • English
    Olives and Olive Oil in Health and Disease Prevention, Second Edition expands the last releases content and coverage, including new sections on materials in packaging, the Mediterranean diet, metabolic syndrome, diabetic health, generational effects, epigenetics, glycemic control, ketogenic diet, antioxidant effects, the use of olive oil in protection against skin cancer, oleuropein and ERK1/2 MAP-Kinase, oleocanthal and estrogen receptors, and oleocanthal and neurological effects. The book is a valuable resource for food and health researchers, nutritionists, dieticians, pharmacologists, public health scientists, epidemiologists, food technologists, agronomists, analytical chemists, biochemists, biologists, physicians, biotechnologists and students.

  • Cancers in the Urban Environment

    How Malignant Diseases Are Caused and Distributed among the Diverse People and Neighborhoods of a Major Global Metropolis
    • 2nd Edition
    • Thomas M. Mack
    • English
    Cancers in the Urban Environment: How Malignant Diseases Are Caused and Distributed among the Diverse People and Neighborhoods of a Major Global Metropolis, Second Edition, provides a detailed description of the occurrence of common forms of cancer in the ethnically, socially and environmentally complex milieu of a modern urban complex. The location is Los Angeles County, and the patterns of 72 different malignancies are described according to race, age, sex, social class calendar time (since 1972) and most notably, individual neighborhood, using detailed maps of high risk. This second edition uses twice as many cases and more demographic diversity. Physicians and scientific investigators in California and elsewhere can use the material provided to counsel patients and evaluate the consistency of any specific pattern of occurrence with each specific causal hypothesis. A detailed appendix describes the source of data, provides the basis for the choices made in the production of the volume, and gives a perspective on the search for "clusters" of malignancy.

  • How Sex and Gender Impact Clinical Practice

    An Evidence-Based Guide to Patient Care
    • 1st Edition
    • Marjorie R. Jenkins + 1 more
    • English
    How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care enables primary care clinicians by providing a framework to understand differences and better care for patients in their practice. Each chapter covers a subspecialty in medicine and discusses the influence of sex hormones on disease, along with sex and gender-based differences in clinical presentation, physical examination, laboratory results, treatment regimens, comorbidities and prognosis. Illustrative case examples and practical practice points help each chapter come alive. A special chapter on communication differences between men and women assists clinicians in their conversations with patients. This book fills an important need by applying years of research findings to sex and gender specific medical care and demonstrating that an individualized approach to patient care will lead to improved detection, treatment and prevention of disease.

  • Aquaculture

    • 1st Edition
    • Volume 38
    • English
    Approx.364 pages

  • Interventional Neuroradiology

    • 1st Edition
    • Volume 176
    • English
    Interventional Neuroradiology, Volume 179, provides a basic outline of the field of interventional neuroradiology that is accessible to fellows, residents, clinicians and researchers in various disciplines, from diagnostic and interventional radiology to vascular neurology, general and vascular neurosurgery, and vascular biology. This volume offers a timely update to experienced clinical practitioners in a logical, easy-to-follow format. Content includes neurovascular anatomy, vascular biology, neurovascular physiology, vascular imaging, as well as sections on the diagnosis and therapeutic treatment of neurovascular disease.

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