Skip to main content
Elsevier

Books in Life sciences

  • Cellular Senescence in Disease

    • 1st Edition
    • Manuel Serrano + 1 more
    • English
    Winner of the 2023 PROSE award in Biomedicine and Neuroscience!Researc... in the field of senescence has boomed recently due to the gradual realization that senescent cells are associated with a significant number of diseases. The genetic or pharmacological elimination of senescent cells can cause widespread benefits and improves outcomes for most of those diseases. Cellular Senescence in Diseases presents an updated review of the role of cellular senescence in multiple pathologies. Focus is given to those diseases where the implication of senescence has been more extensively documented, such as (cancer, lung and liver diseases, diabetes, Neurodegenerative diseases and others).The Editors recruited a group of worldwide experts in each individual pathology to review the role of cellular senescence in each one of them, aiming at identifying potential therapeutic pathways. The first two chapters provide an overview of the cellular senescence principles. Next, the chapters are divided into specific diseases. Cancer, including premalignant lesions (OIS), Advanced disease (TIS), and Metastasis are covered. The following condition covered is Lung diseases, including IPF, COPD, and Pulmonary Hypertension. Next Liver Diseases are covered, including Fibrosis and Cirrhosis, and Fatty liver disease. Next there is coverage for Kidney implications, including fibrosis and transplantation. Vascular diseases are covered next including infarction and hear fibrosis, and atherosclerosis. Both diabetes types 1 and 2 are covered next. Following chapters cover Obesity, Sarcopenia, and Bone and Cartilage disorders, respectively. Neurodegenerative diseases are covered next, focusing on Alzheimer's and Parkinson's. The next chapter discusses accumulation of senescent cell in tissues during aging. The two final chapters cover current developments and conclusions.Cellular Senescence in Diseases is designed for researchers and clinicians with a focus on the cellular mechanisms of diseases. All chapters cover current experimental therapeutic approaches to eliminate or cancel the pathological effects of senescent cells. Pharmaceutical scientists may also benefit from the contents of the book in the exploration of novel therapeutic opportunities.

  • Brain Tumor MRI Image Segmentation Using Deep Learning Techniques

    • 1st Edition
    • Jyotismita Chaki
    • English
    Brain Tumor MRI Image Segmentation Using Deep Learning Techniques offers a description of deep learning approaches used for the segmentation of brain tumors. The book demonstrates core concepts of deep learning algorithms by using diagrams, data tables and examples to illustrate brain tumor segmentation. After introducing basic concepts of deep learning-based brain tumor segmentation, sections cover techniques for modeling, segmentation and properties. A focus is placed on the application of different types of convolutional neural networks, like single path, multi path, fully convolutional network, cascade convolutional neural networks, Long Short-Term Memory - Recurrent Neural Network and Gated Recurrent Units, and more. The book also highlights how the use of deep neural networks can address new questions and protocols, as well as improve upon existing challenges in brain tumor segmentation.

  • Postharvest and Postmortem Processing of Raw Food Materials

    Unit Operations and Processing Equipment in the Food Industry
    • 1st Edition
    • Seid Mahdi Jafari
    • English
    Postharvest and Postmortem Processing of Raw Food Materials, a volume in the Unit Operations and Processing Equipment in the Food Industry series, presents the processing operations and handling of agricultural crops, animal products, and raw food materials after their harvesting/slaughter... and entrance into food production factories. Chapters in this new release cover an Introduction to postharvest and postmortem technology, Primary operations in postharvest processing, Disintegration of raw agricultural crops, Disintegration with little changes in form (Husking, Shelling, Pitting, Coring, Snipping and Destemming), Disintegration with considerable changes in form (Cutting/dicing, crashing and grinding, Slaughtering, Shredding, Sheeting), and much more. Written by experts in the field of food engineering, and in a simple and dynamic way, this book targets all who are engaged in food processing operations worldwide, giving readers good knowledge on the basics of food engineering principles and applications.

  • Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy

    • 1st Edition
    • Volume 3
    • Peder Larson
    • English
    MRI with hyperpolarized carbon-13 agents is a powerful emerging imaging modality that can measure real-time metabolism in cells, animals, and humans. It uses endogenous, non-toxic contrast agents that a hyperpolarized, resulting in up to 100,000-fold increases in sensitivity. This technique uses no ionizing radiation, and is being applied in a range of human trials. It’s primary use is for metabolic imaging, but it can also measure perfusion, pH, and necrosis. Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy is designed to be a one stop shop for understanding hyperpolarized 13C MRI. This book explains the principles of this imaging modality, the requirements for performing studies, shows how to interpret the results, and gives an overview of current biomedical applications. It is suitable for engineers, scientists and clinicians in radiology and biomedical imaging who want to understand this technology.

  • The Rise of Chance in Evolutionary Theory

    A Pompous Parade of Arithmetic
    • 1st Edition
    • Charles H. Pence
    • English
    The Rise of Chance in Evolutionary Theory: A Pompous Parade of Arithmetic explores a pivotal conceptual moment in the history of evolutionary theory: the development of its extensive reliance on a wide array of concepts of chance. It tells the history of a methodological and conceptual development that reshaped our approach to natural selection over a century, ranging from Darwin’s earliest notebooks in the 1830s to the early years of the Modern Synthesis in the 1930s. Far from being a “pompous parade of arithmetic,” as one early critic argued, evolution transformed during this period to make these conceptual and technical tools indispensable. This book charts the role of chance in evolutionary theory from its beginnings to the earliest days of modern evolutionary theory, making it an ideal resource for evolutionary biologists, historians, philosophers, and researchers in science studies or biological statistics.

  • High Oleic Oils

    Development, Properties, and Uses
    • 1st Edition
    • Frank J. Flider
    • English
    High Oleic Oils: Development, Properties and Uses is the first complete reference to address practical applications for this new and dynamic category of fats and oils that are essentially replacing partially hydrogenated oils in various food and nonfood uses. As a category, high oleic oils are highly stable, but like other fats and oils, there are differences in the composition and applications of the various types of high oleic oils. Their compositions allow for the production of a range of frying oils, increased shelf-life foods, functional shortenings and hard fats, and even industrial products not easily produced with nonhigh oleic oils. Information and know-how on these applications and advantages has been in high demand and short supply until now.Based on extensive commercial experience, seminars and presentations, Editor Frank Flider has identified common customer questions, needs and concerns about high oleic oils, and addresses them in this single comprehensive volume outlining development, composition, and utilization of high oleic oils. Through the individual expertise of a highly qualified team of contributing authors, this book outlines the development, composition, and utilization of these oils, making it of value to a wide range of readers, including the research and development industry and academic researchers.

  • Polycystic Ovary Syndrome

    Challenging Issues in the Modern Era of Individualized Medicine
    • 1st Edition
    • Evanthia Diamanti-Kandarakis
    • English
    Women’s healthcare regarding polycystic ovarian syndrome remains challenging. Patients often go from one specialist to another trying to fully understand and management the disorder. Women often go years before a diagnosis, seeing three or more doctors before a confirmed diagnosis. Polycystic Ovarian Syndrome: Challenging Issues in the Modern Era of Individualized Medicine brings together multiple medical disciplines to improve the care of women with PCOS. Such a multidisciplinary clinical and scientific approach integrates obstetrics and gynecology, pediatric and medical endocrinology, internal medicine, genetics, psychology and laboratory medicine into relevant translational clinical and scientific discussions that update both the scientific understanding of PCOS and the diagnosis and management of all aspects of the syndrome. The impact of PCO on the onset of puberty is subdivided in sub sections to get a better understanding of this condition and the management at different stages in a woman’s life.

  • Viral Replication Enzymes and their Inhibitors Part B

    • 1st Edition
    • Volume 50
    • English
    Viral Replication Enzymes and their Inhibitors, Part B, Volume 50 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics surrounding enzymes.

  • Advances in Immunology

    • 1st Edition
    • Volume 152
    • Frederick W. Alt
    • English
    Advances in Immunology, Volume 152, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology, including chapters that cover Renal diseases and the role of complement in their pathogenesis, Factor H and Properdin and their regulation, Complement in neuronal diseases, Complement and the brain.

  • Microbial Diversity and Ecology in Hotspots

    • 1st Edition
    • Aparna Gunjal + 1 more
    • English
    Microbial Diversity in Hotspots provides an introduction to microbial diversity and microbes in different hotspots and threatened areas. The book gives insights on extremophiles, phyllosphere and rhizosphere, covers fungal diversity, conservation and microbial association, focuses on biodiversity acts and policies, and includes cases studies. Microbes explored are from the coldest to the hottest areas of the world. Although hotspots are zones with extremely high microbiology activities, the knowledge of microbial diversity from these areas is very limited, hence this is a welcome addition to existing resources.

Related subjects