Advances in Immunology
- 1st Edition, Volume 152 - November 25, 2021
- Imprint: Academic Press
- Editor: Frederick W. Alt
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 2 4 6 0 0 - 9
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 5 0 8 6 - 5
Advances in Immunology, Volume 152, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immuno… Read more
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Request a sales quoteAdvances in Immunology, Volume 152, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology, including chapters that cover Renal diseases and the role of complement in their pathogenesis, Factor H and Properdin and their regulation, Complement in neuronal diseases, Complement and the brain.
- Presents current developments and comprehensive reviews in immunology
- Provides the latest in a longstanding and respected serial on the subject matter
- Focuses on recent advances in the advancing area of the mechanisms involved in the evolution of HIV-1 Neutralizing Antibodies
Immunologists and infectious disease specialists, cell biologists and hematologists.
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Chapter One: Renal diseases and the role of complement: Linking complement to immune effector pathways and therapeutics
- Abstract
- 1: Introduction
- 2: The complement system
- 3: Effector mechanisms recruited by complement
- 4: Local production of complement by kidney cells
- 5: Drugs targeting the complement system
- 6: Impact of complement on kidney diseases
- 7: Conclusions
- References
- Chapter Two: Neuropsychiatric disorders: An immunological perspective
- Abstract
- 1: Introduction
- 2: Neuropsychiatric diseases with an immune component
- 3: Immune diseases with a neuropsychiatric component
- 4: Immunological perspectives to studying neuropsychiatric disease
- 5: Conclusion
- References
- Chapter Three: Complement as a powerful “influencer” in the brain during development, adulthood and neurological disorders
- Abstract
- 1: The complement system
- 2: Complement mediated events in neurogenesis, migration, development, and aging
- 3: Complement and neuroinflammation
- 4: Complement in neurological diseases and disorders
- 5: Therapeutic modulation of the complement system for neurologic disorders
- 6: Conclusions
- References
- Edition: 1
- Volume: 152
- Published: November 25, 2021
- No. of pages (Hardback): 230
- No. of pages (eBook): 230
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780128246009
- eBook ISBN: 9780323850865
FA
Frederick W. Alt
Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.
Affiliations and expertise
Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USARead Advances in Immunology on ScienceDirect