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Elsevier

Books in Life sciences

  • Nanoengineered Therapeutics for Lung Cancer

    Advanced Drug Delivery Strategies
    • 1st Edition
    • Arun Kumar Singh + 4 more
    • English
    Nanoengineered Therapeutics for Lung Cancer: Advanced Drug Delivery Strategies explores contemporary methods for diagnosing and treating lung cancer using cutting-edge nanotechnology. The book provides a foundational understanding of lung cancer biology, detailing innovative nanodrug delivery strategies and their practical applications in treatment. The content is strategically structured, covering the design, synthesis, and application of nanodrug delivery systems. Chapters delve into specific technologies such as gold nanoparticles, exosome-mediated therapies, and siRNA-based gene silencing. The book also addresses challenges like drug resistance and toxicity, offering insights into future research directions and advancements in the field. This book benefits graduate students, researchers, and healthcare professionals by seamlessly integrating theoretical concepts with practical applications. It serves as an essential educational resource, equipping readers with the knowledge and skills needed to tackle complex challenges in lung cancer treatment using nanomedicine. This comprehensive guide ensures that readers stay at the forefront of the rapidly evolving landscape of cancer therapeutics.

  • Advancing Body Fluid Diagnostics with Flow Cytometry

    A Comprehensive Guide to Effusions and CSF
    • 1st Edition
    • Namrata P. Awasthi
    • English
    Advancements in Pathological Diagnosis: Harnessing Flow Cytometry for Detection of Malignant Epithelial Cells in Body Fluids is an invaluable resource for anyone involved in cytology and pathology, especially those interested in leveraging flow cytometry for diagnostic purposes. The book offers a comprehensive understanding of how flow cytometry can enhance the detection of malignant epithelial cells in body fluids, providing both theoretical knowledge and practical guidance. Flow cytometry's ability to rapidly analyze individual cells based on their properties is truly remarkable, and its application in detecting early-stage malignancies and screening large numbers of cells efficiently is invaluable. The book bridges the gap between traditional cytological diagnostics and the evolving landscape of technological advancements in pathology. Moreover, the inclusion of detailed chapters on flow cytometry and its applications in cytological diagnostics for effusion samples suggests that the book caters to both beginners in the field and seasoned professionals seeking to expand their knowledge base. The endorsement from medical professionals such as medical oncologists, surgical oncologists, gastroenterologists, and general surgeons further underscores the relevance and practicality of the book in enhancing diagnostics and patient care across various medical specialties. "Advancements in Pathological Diagnosis" is a timely and essential contribution to the field of cytology and pathology, offering a comprehensive guide to leveraging flow cytometry for improved diagnostics in the context of malignant epithelial cells in body fluids.

  • Advances in Noncoding RNA Diagnostics and Therapeutics in Immunity and Cancer

    • 1st Edition
    • Afsar Naqvi + 1 more
    • English
    Advances in Noncoding RNA Diagnostics and Therapeutics in Immunity and Cancer explores the critical role of noncoding RNAs in immune-mediated diseases and cancers, providing an essential resource on their diagnostic and therapeutic potential. The book contributes valuable insights into the pathobiology of noncoding RNAs and their application in various diseases, delving into the latest research on noncoding RNAs, including their mechanisms, interactions, and roles in disease. In addition, it examines how noncoding RNAs influence immune responses, inflammation, and cancer progression. With a focus on both diagnostic and therapeutic applications, this book highlights the potential of noncoding RNAs as biomarkers and therapeutic targets. Across comprehensive chapters, the book covers a wide range of topics, including the role of virus-encoded microRNAs in immune evasion, the therapeutic aspects of non-coding RNA in hepatocellular carcinoma, the impact of microRNAs in periodontal inflammation, and the involvement of miRNAs and lncRNAs in regulating the tumor microenvironment in HCC. Other chapters explore the functions and clinical value of tumor-derived exosomes and miRNAs in cancer immune response, the interaction of noncoding RNA in cancer metastasis, and a panorama of non‐coding RNA in prostate cancer. This book is an invaluable resource for basic science researchers in the noncoding RNA field, cancer biologists, immunologists and RNA biologists interested in the latest advancements in noncoding RNA research.

  • Metabolomic Phenotyping for the Future of Personalized Medicine

    Beyond the Biomarkers
    • 1st Edition
    • Jacopo Troisi + 1 more
    • English
    Metabolomic Phenotyping for the Future of Personalized Medicine: Beyond the Biomarkers takes a critical look at the advancements in the field. It begins by explaining the essential steps of metabolomics analysis—from sample collection to data interpretation—while exploring how these workflows pave the way for targeted medical applications. With a focus on precision, it shows how metabolomics provides key insights into the mechanisms behind diverse phenotypes, making it an indispensable asset for biomedical research. The second section dives into the transformative results achieved in major medical domains through metabolomics, detailing how this emerging science contributes to understanding complex disease mechanisms.The book also outlines the international regulatory framework essential for conducting research within this field, ensuring compliance and ethical standards. By combining practical guidelines with visionary insights, this text serves as a cornerstone for future strides in personalized medicine and highlights the growing influence of metabolomics in shaping tomorrow’s healthcare systems.

  • The Inflammatory Ecosystem and Inflammazones

    Mapping the Complex Terrain of Inflammatory Diseases
    • 1st Edition
    • Erwei Song + 1 more
    • English
    The Inflammatory Ecosystem and Inflammazones offers a groundbreaking framework for understanding inflammation across multiple spatial and molecular levels. It introduces the concept of distinct inflammazones—local, regional, distal, and systemic—and explores how their interactions influence disease development, progression, and resolution. This holistic approach integrates cellular, molecular, microbiome, and systemic responses, addressing a critical gap in current knowledge and advancing diagnostics and therapies for diseases like autoimmunity and cancer. The book is organized into six sections, starting with foundational principles and progressing through mechanisms of local, regional, and systemic inflammazones. It covers key components such as cytokines, chemokines, immune cells, and the roles of non-immune cells like fibroblasts and epithelial cells. The final sections focus on systems-level insights, including inflammaging, metabolism, and multi-omics technologies, culminating in strategies for personalized medicine and clinical translation. Each chapter combines cutting-edge research with clinical relevance, making complex concepts accessible and actionable. The Inflammatory Ecosystem and Inflammazones is essential for researchers and clinicians seeking to understand the complex landscape of inflammation. It highlights disease heterogeneity, emerging therapeutic targets, and the importance of systems biology, providing the foundational knowledge to shape future inflammation research and treatment strategies.

  • Smart Biosensing Technologies for Early Detection of Metabolic Disorders

    • 1st Edition
    • Kanwal Rehman + 1 more
    • English
    Smart Biosensing Technologies for Early Detection of Metabolic Disorders gives a clear overview of the latest biosensor tools that help detect and monitor metabolic diseases like diabetes, obesity, and insulin resistance early. It explains how these sensors work using basic science and shows new wearable, non-invasive, and easy-to-use devices. This book is useful for researchers, doctors, and professionals working in healthcare technology. This book connects research from different fields to help solve real problems in making and using biosensors. It includes examples of how these sensors are used, new markers for disease detection, and how AI and digital health can improve care. Readers will learn how to develop better diagnostic tools and improve treatment for metabolic diseases.

  • Recent Advances in Molecular Docking

    Methods, Tools, and Applications
    • 1st Edition
    • Khalid Raza
    • English
    Recent Advances in Molecular Docking: Methods, Tools, and Applications offers an authoritative guide to modern molecular docking techniques, emphasizing the integration of artificial intelligence and machine learning. The volume covers foundational principles, computational workflows, and advanced scoring functions, providing researchers and practitioners with practical tools to improve drug-target interaction predictions. It highlights applications across pharmaceuticals, including cancer, neurological disorders, and infectious diseases, which are all supported by real-world case studies. Challenges in docking accuracy, reproducibility, validation, and ethical and regulatory considerations are also covered.Authored by international experts, it bridges theoretical knowledge with practical applications, making it an essential resource for computational biologists, pharmacologists, and drug developers aiming to leverage AI-driven docking in precision medicine.

  • Surgical and Non-Surgical Advances in Stroke Management and Therapeutics

    • 1st Edition
    • Creed M. Stary + 2 more
    • English
    Surgical and Non-Surgical Advances in Stroke Management and Therapeutics offers a comprehensive exploration of contemporary stroke care. This essential resource synthesizes the latest research and clinical innovations, providing in-depth insights into advanced surgical techniques, emerging therapies, and interdisciplinary approaches to stroke treatment. Readers will gain a thorough understanding of both acute and chronic stroke management, enriched by expert commentary from leading clinicians and researchers. Covering everything from pioneering non-invasive interventions to state-of-the-art surgical strategies, this book delivers a critical framework for healthcare professionals dedicated to optimizing patient outcomes and rehabilitation.

  • Geriatric Neurosurgery in Clinical Practice

    • 1st Edition
    • Joe M. Das
    • English
    Geriatric Neurosurgery in Clinical Practice is an essential resource that provides a thorough and modern overview of geriatric neurosurgery. This volume compiles the latest research and clinical practice guidelines, offering practical advice for clinicians caring for elderly patients. It delves into a range of topics, including the management of common neurosurgical conditions in elderly patients, surgical techniques, postoperative care, and the integration of multidisciplinary approaches to enhance patient outcomes. Users will find this to be an invaluable reference for practicing neurosurgeons, neurosurgery residents, neurologists, geriatric physicians, and researchers seeking clear and concise information on current treatments and procedures for geriatric neurosurgery.

  • Building Blocks of Neuroimmunometabolism

    From Molecular Pathways to Therapeutic Strategies
    • 1st Edition
    • Sachchida Nand Rai + 2 more
    • English
    Building Blocks of Neuroimmunometabolis... From Molecular Pathways to Therapeutic Strategies offers an authoritative exploration of the intricate relationship between the immune system and neurodegenerative diseases. This essential resource addresses the critical gap in understanding how immune responses and metabolic processes jointly influence the onset and progression of conditions such as Alzheimer’s, Parkinson’s, and multiple sclerosis. The book provides a comprehensive examination of key molecular pathways and cellular interactions, emphasizing the role of immunometabolism in disease mechanisms.Beginning with an introduction to the concept of immunometabolism, the book explores the connections between the immune and nervous systems, setting the stage for understanding neurodegenerative diseases. It discusses pivotal topics such as the role of microglia and macrophages in neuroinflammation, the metabolic regulation of T cells, and the impact of oxidative stress and mitochondrial dysfunction. The gut-brain axis is examined for its influence on brain health, alongside innovative therapeutic strategies targeting immunometabolic pathways and lifestyle interventions.Buildi... Blocks of Neuroimmunometabolis... From Molecular Pathways to Therapeutic Strategies is invaluable for researchers, clinicians, and students seeking to understand the complex interactions driving neurodegeneration. The book offers cutting-edge insights into immunometabolism, highlighting its potential to revolutionize therapeutic strategies and improve patient outcomes in neurodegenerative disorders.

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