
Mathematical Concepts and Methods in Modern Biology
Using Modern Discrete Models
- 2nd Edition - November 1, 2025
- Imprint: Academic Press
- Editor: Raina Robeva
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 2 9 6 5 2 - 9
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 9 6 5 3 - 6
Mathematical Concepts and Methods in Modern Biology: Using Modern Discrete Models, Second Edition offers an updated, quantitative framework essential for analyzing, predic… Read more

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Request a sales quoteMathematical Concepts and Methods in Modern Biology: Using Modern Discrete Models, Second Edition offers an updated, quantitative framework essential for analyzing, predicting, and modulating the behavior of complex biological systems. This book, structured around project-based learning and problem-solving principles, integrates crucial mathematical concepts, methods, and tools contextualized by vital questions raised in modern biology. Topics covered include neuronal networks, plant population growth, metabolic pathways, and phylogenetic tree reconstruction. New mathematical modeling tools featured include Boolean and ordinary differential equations, projection matrices, agent-based modeling, and several algebraic approaches. Updated software manuals and codes are provided, making this a valuable resource for health professionals, scientists, researchers, and students in related fields.
- Provides fully updated and expanded content, examples, exercises, and projects on modern discrete mathematics and algebraic statistics
- Includes updated computer codes and software manuals to reflect the current state of the field
- Prepares readers, through examples, exercises, and carefully selected projects to transition successfully to engaging in student research and reading the research literature
- Introduces discrete and algebraic methods in the context of important questions from modern biology at a level requiring minimal mathematical background
- Emphasizes the use of specialized software as a necessary element of the modern biology skills set by integrating freely available applications and mainstream proprietary software in the presentation
Researchers in algebraic biology, mathematical and computational biology
1. Modeling Gene Regulation Using Boolean Network Models
2. Bistability in Bacterial Genetic Networks
3. Inferring the Topology of Gene Regulatory Networks: An Algebraic Approach to Reverse Engineering
4. Stochastic Boolean Networks b including Probabilistic Boolean networks, perturbed Boolean networks, and probabilistic edge operators.
5. Global Dynamics Emerging from Local Interactions: Agent-Based Modeling for the Life Sciences
6. Agent-Based Models and Optimal Control in Biology: A Discrete Approach
7. Neuronal Networks: A Discrete Model by (TBD) Proposed Updates: P
8. Predicting Population Growth: Modeling with Projection Matrices b
9. Metabolic Pathway Analysis: A Linear Algebra Approach by (TBD)
10. Identifying CpG Islands Using Hidden Markov Models
11. Tropical Linear Algebra Approaches in Phylogenetics
12. Phylogenetic Tree Reconstruction: Geometric Approaches Pl
2. Bistability in Bacterial Genetic Networks
3. Inferring the Topology of Gene Regulatory Networks: An Algebraic Approach to Reverse Engineering
4. Stochastic Boolean Networks b including Probabilistic Boolean networks, perturbed Boolean networks, and probabilistic edge operators.
5. Global Dynamics Emerging from Local Interactions: Agent-Based Modeling for the Life Sciences
6. Agent-Based Models and Optimal Control in Biology: A Discrete Approach
7. Neuronal Networks: A Discrete Model by (TBD) Proposed Updates: P
8. Predicting Population Growth: Modeling with Projection Matrices b
9. Metabolic Pathway Analysis: A Linear Algebra Approach by (TBD)
10. Identifying CpG Islands Using Hidden Markov Models
11. Tropical Linear Algebra Approaches in Phylogenetics
12. Phylogenetic Tree Reconstruction: Geometric Approaches Pl
- Edition: 2
- Published: November 1, 2025
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780443296529
- eBook ISBN: 9780443296536
RR
Raina Robeva
Raina Robeva was born in Sofia, Bulgaria. She holds a PhD in Mathematics from the University of Virginia and has broad research interests spanning theoretical mathematics, applied probability, and systems biology. Robeva is the founding Chief Editor of the journal Frontiers in Systems Biology and the lead author/editor of the books An Invitation to Biomathematics (2008), Mathematical Concepts and Methods in Modern Biology: Using Modern Discrete Models (2013), and Algebraic and Discrete Mathematical Methods for Modern Biology (2015), all published by Academic Press. She is Professor of Mathematical Sciences and Director of the Center for Science and Technology in Society at Sweet Briar College.
Affiliations and expertise
Professor of Mathematical Sciences, Sweet Briar College, VA, USA