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Elsevier

Books in Life sciences

  • Biochemical and Molecular Aspects of Selected Cancers

    Volume 2
    • 2nd Edition
    • Thomas G. Pretlow II
    • English
    This two-volume work not only includes much of the newer molecular biology research but also important earlier research in this area essential for the comprehensive understanding of the biochemistry of neoplastic diseases. As such it will provide an invaluable source of information for the young investigator. Human cancers, not experimental models of cancer, are emphasized.

  • Human Atheroma

    With Particular Reference to Endocrine Aspects of Ætiology
    • 1st Edition
    • W. L. Ashton
    • English
    Human Atheroma (with Particular Reference to Endocrine Aspects of Aetiology) examines the endocrinological features of human atherosclerosis. This book is composed of 11 chapters that discuss the pathological sequelae and descriptive epidemiology of atheroma, commonly known as atherosclerosis. This book also addresses the mechanisms of arterial occlusion in the disease and the epidemiological observations on atherosclerosis. Some of the topics covered in the book are the clinical and pathological observations on atherosclerosis; common considerations in the association of endocrine with the disease; ovarian function and atheromatous disease; relationship between thyroid function and atherosclerosis; and clinical and epidemiological connections of atheroma and insulin. Other chapters deal with the associations between the development of diabetes mellitus and insulin, as well as the assay methods for insulin and insulin antagonists. An analysis of the hormonal disturbances in diabetic patients and their relatives is provided. The remaining chapters consider the insulin antagonism in diabetes mellitus and the measures suggested to decrease the number of atherosclerotic patients. The book can provide useful information to the cardiologists, doctors, students, and researchers.

  • Nutrition and Lactation in the Dairy Cow

    • 1st Edition
    • Philip C. Garnsworthy
    • English
    Nutrition and Lactation in the Dairy Cow is the proceedings of the 46th University of Nottingham Easter School in Agricultural Science. Said symposium was concerned with the significant advances in the field of nutrition and lactation in the dairy cow. The book is divided in five parts. Part I deals with the principles behind nutrition and lactation of cows. Part II discusses the cow’s nutrient interactions; responses to nutrients that yield protein and energy; and the influence of nutrient balance and milk yields. Part III tackles the efficiency of energy utilization in cows and its relation to milk production. Part IV talks about food intake of cows and the factors that affect it, while Part V deals with the different feeding systems for cows. The text is recommended for those involved in raising cows and dairy production, especially those who would like to know more and make studies about the relationship of nutrition and lactation of cows.

  • Advances in Immunopharmacology

    Proceedings of the Second International Conference on Immunopharmacology, July 1982, Washington, USA
    • 1st Edition
    • J. W. Hadden + 1 more
    • English
    The second of two volumes covering the most recent developments in this new field. Like the previous volume, this book brings together the two fields of immunology and pharmacology, and offers a review format for advances in basic aspects, as well as an update in discussion format of therapy-related advances.

  • Recent Advances in Animal Nutrition

    • 1st Edition
    • P. C. Garnsworthy + 2 more
    • English
    Recent Advances in Animal Nutrition: 1992 is an annual review of the changes and updates in the field of animal nutrition, especially progresses in the study of feeds. The book is divided into four parts. Part I discusses topics related to nutrition in non-ruminant animals, while Part II covers ruminant nutrition. Part III tackles studies about general nutrition such as the use of growth promoters in animal feeds and predicting the response to variation and diet, and Part IV deals with feed compounding and its effects. The text is recommended for agriculturists, zoologists, and those involved in the development and manufacture of feeds who would like to know more about the nutrition of agriculturally important animals.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 8
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume VIII covers a critical review and new extensions of quantitative methods in drug design, the design of particular types of agents, such as synthetic sweeteners, and selective ion binding compounds. The book discusses the advances in the methodology of quantitative drug design; the application of pattern recognition to drug design; and the design of controlled drug delivery systems. The text also describes the use of receptor binding as a tool in the development of new bioactive steroids; the design of synthetic sweeteners; and the prospective assessment of environmental effects of chemicals. The design of selective ion binding macrocyclic compounds and their biological applications are also encompassed. Chemists, pharmacologists, biochemists, and people involved in drug design and manufacture will find the book invaluable.

  • Current Problems in the Epidemiology of Cancer and Lymphomas

    Recent Results in Cancer Research
    • 1st Edition
    • E. Grundmann + 1 more
    • English
    Recent Results in Cancer Research: Current Problems in the Epidemiology of Cancer and Lymphomas is a collection of papers that tackles the various areas of concerns in cancer research. The text covers the general problems, such as the histopathological definition and classification of tumors. The book also deals with the various types of cancer, such as breast, liver, and prostrate cancers. The selection will be of great use for medical researchers and practitioners, particularly those who are involved in treating and studying cancers.

  • Atlas of Human Tumor Cell Lines

    • 1st Edition
    • Robert K.M. Hay + 2 more
    • English
    Human tumor cells in culture are valuable for studying cancer causes and properties. This convenient reference provides useful information for cancer researchers on commonly used, established tumor cell lines of the major human organ systems.Atlas of Human Tumor Cell Lines includes data about morphological, metabolic, genetic, and growth characteristics of human tumor cells, with morphological characteristics presented in more than 250 photomicrographs. It also contains information for establishing and maintaining human tumor cell lines in culture, and each chapter covers future perspectives.

  • Muscle Function Testing

    • 1st Edition
    • Vladimír Janda
    • English
    Muscle Function Testing provides information pertinent to the muscle functions. This book evaluates the method of examination that provides information about the strength of individual muscles or muscle groups that form a functional unit. Organized into three sections encompassing four parts, this book begins with an overview of the size, extent, and progress of peripheral nerve lesions. This text then discusses the nature of the simple movement pattern seen in muscle function testing. Other chapters consider the conditions for analytical physiotherapy and determination of the work capacity of the part of the body being tested. This book discusses as well the possible errors and mistakes that might occur during testing and might decrease the validity of the assessment. The final chapter deals with the demand for a better and a more rational method to therapeutic exercise. This book is a valuable resource for physiotherapists, orthopedic surgeons, physiologists, neurologists, and rheumatologists.

  • Plant Diseases

    Epidemics and Control
    • 1st Edition
    • J. E. Van Der Plank
    • English
    Plant Diseases: Epidemics and Control provides a description of the methods of epidemiological analysis based on infection rates and the relation between the amount of inoculum and the amount of disease it produces. The book shows how to study the increase of pathogen populations and the epidemiological strategy to be adopted to control the epidemic of plant diseases. The text covers the calculation of the logarithmic increase of disease; use of epidemiology in the study of control; forms of sanitation; the use of resistant plant varieties; and the design of field experiments. Plant pathologists and breeders, agriculturists, horticulturists, research workers, teachers, and students will find the text invaluable.

  • Cisplatin

    Current Status and New Developments
    • 1st Edition
    • Archie W. Prestayko
    • English
    Cisplatin: Current Status and New Developments is a collection of papers presented at a symposium sponsored by the University of Alabama in Birmingham Comprehensive Cancer Center and the Bristol Laboratories in Syracuse, ?ew York, and held on September 27-28, 1979, in Atlanta, Georgia. The symposium provided a forum for assessing developments with regards to cisplatin as an anticancer drug, with emphasis on its clinical application in a wide variety of adult and pediatric malignancies as well as the mechanism by which the drug appears to cause tumor cell death. Comprised of 39 chapters, this book begins with a preclinical overview of cisplatin, focusing on its mechanism of action, pharmacology, antitumor activity, analogs, and toxicity. The discussion then turns to the effects of cisplatin on DNA and the possible relationships to cytotoxicity and mutagenicity in mammalian cells; lethal activity of platinum compounds in combination with pyrimidine derivatives; and ultrastructural effects of cisplatin. Subsequent chapters focus on the rationale of combination chemotherapy; toxic side effects of platinum analogs; radiopharmacokinetic... of cisplatin; and the use of cisplatin for the treatment of malignancies such as ovarian cancer and advanced adenocarcinoma of the prostate. This monograph will be useful to oncologists and pharmacologists.

  • The Effect of Modern Agriculture on Rural Development

    Comparative Rural Transformation Series
    • 1st Edition
    • Gyorgy Enyedi + 1 more
    • English
    The Effect of Modern Agriculture on Rural Development discusses the role of agriculture in rural development and analyzes the interaction between the social and technical aspects of rural development. The 22 chapters of the text are organized into five parts. Part I discusses social changes, modernization of agriculture, and process of rural transformation, and Part II deals with modernizing agriculture and the rural settlement pattern. Part III tackles agrotechniques and rural change, while Part IV covers the industrialization of agriculture and villages. Part V discusses agro-industrial integration and rural transformation. The book will be of great interest to individuals concerned with the effects of the modernization of agriculture on rural areas.

  • Anatomy and Human Movement

    Structure and Function
    • 1st Edition
    • Nigel Palastanga + 2 more
    • English
    Anatomy and Human Movement: Structure and Function describes the musculoskeletal structures of the human body and the biomechanics behind their movements. The book provides anatomical descriptions of bone and muscle groups with emphasis on the joints; enumeration of common traumatic or pathological problems affecting the musculoskeletal structures; and the use of palpation through intact skin to describe the structures, as well as how movements can be tested and analyzed with respect to joint movement, muscle work and function. Chapters on embryology; the skin and its appendages; terminologies used in the book; and an account of the structure and function of the nervous system are included as well. Students of anatomy will find the text a valuable reference material.

  • Infectious Diseases

    • 2nd Edition
    • A. Melvin Ramsay + 1 more
    • English
    Infectious Diseases, Second Edition furnishes the basic facts regarding the common infections encountered in the British Isles. The infectious diseases covered in this edition include varicella and herpes zoster, smallpox, tetanus, measles, mumps, influenza, and acute respiratory disease. The poliomyelitis, Stevens-Johnson syndrome, malaria, tuberculosis, cytomegalic inclusion disease, and rabies are also discussed. This book likewise deliberates the host-parasite relationship, control of infection in hospitals, sterilization and disinfection, pyrexia of undetermined origin (PUO), and public health law. This publication is valuable not only to clinicians but also to epidemiologists, microbiologists and community physicians whose work is connected with the many problems in the field of acute medicine.

  • Agrochemicals in Soils

    • 1st Edition
    • A. Banin + 1 more
    • English
    Agrochemicals in Soils contains selected papers from a joint meeting of the Soil Chemistry, Soil Fertility, and Soil Clay Mineralogy Commissions of the International Society of Soil Science, in Jerusalem, Israel. The book is organized into four parts. Parts 1 and 2 deal mostly with the chemical reactions of agrochemicals in the soil. Part 3 explores the movement of agrochemicals in the soil and Part 4 elucidates some aspects of agrochemicals and pollution. Each section begins by one or two invited papers presenting an overview of the topic of the section. Contributed papers follow reporting the results of experimental studies and theoretical analyses of related specific topics. This book will contribute to a better understanding and efficient control of the soil environment.

  • The Chemistry and Bacteriology of Public Health

    • 1st Edition
    • C. L. Dunn + 1 more
    • English
    The Chemistry and Bacteriology of Public Health deals with public health hygiene. This book reviews the alkalimetry, acidimetry, standard solutions, normal solutions, and the preparation of solutions in public health laboratories, including methods of estimating equivalent weights of substances. In collecting water samples for analysis, the investigator should avoid all sources of extraneous contamination. The Wanklyn's process analyzes organic matter in the water: different tests give quantitative estimates of water contamination or bacterial purity. The authors point that the process of analyzing sewage and sewage effluents are the same as in water analysis except that sewage is diluted with distilled water. The authors also explain how air and water are analyzed, soil analysis being a complex process. The authors discuss milk analysis (fresh, boiled, skimmed, powdered, condensed), butter, cheese, food grains. Microscopic examination of bacteria from samples taken are examined alive, in film preparations, or in sections. The book describes in detail the different types of bacteria, their occurrence, and how these are examined or cultured. This book is intended as a laboratory handbook for students taking up the examination in Public Health. The book can also prove beneficial for social worker, public health officials, and for undergraduate medical students.

  • The Origin Nature and Evolution of Protoplasmic Individuals and Their Associations

    Protoplasmic Action and Experience
    • 1st Edition
    • Faustino Cordon
    • English
    The Origin, Nature and Evolution of Protoplasmic Individuals and their Associations explores living beings of all levels of complexity in relation to each other and to the various ambient sources that they use to survive: protoplasmic individuals and their associations, cells and their associations, animals, and man. The book considers the concepts of evolution and of living beings; the main stages in biological evolution; the organisms' individuality, nature, way of formation, phylogenetic, and ontogenetic origin; essential property of the organisms of living beings; and creature modeling. The text also discusses the phylogenesis, ontogenesis, and the nature of the soma; the spatial and temporal environment connecting biological and geological evolution; and concepts of feeding and nutrition. Three separate sections describe phylogenetic origin of the first protoplasmic individuals; the protoplasmic individual as defined by its action and experience; and evolution in protoplasmic level.

  • Spinal Degenerative Disease

    • 1st Edition
    • R. S. Maurice-Williams
    • English
    Spinal Degenerative Disease aims to provide a guide to the subject of spinal degenerative disease in all its aspects and to provide a balanced account of the more controversial parts of this field. It was written to fill the lack of books that deal with the degenerative disease of the vertebral column. This book is organized into 14 chapters that attempt to cover not only the pathology, clinical features, and treatment of spinal degenerative disease but also some relevant topics such as radiological techniques used in spinal investigation and the relationship between spinal arachnoiditis and degenerative disease. The book also discusses the relevant aspects of normal spinal physiology and anatomy and the differential diagnosis of spinal pain and sciatica. It also provides case histories to illustrate various points. This book will be of interest to students, medical professionals, and others interested in understanding the pathology and treatment of spinal degenerative disease.

  • The Toxicology of Radioactive Substances

    Volume 5
    • 1st Edition
    • A. A. Letavet + 1 more
    • English
    The Toxicology of Radioactive Substances, Volume 5: Zinc-65 deals with the toxic properties of the radioisotope zinc-65 as well as its biological effects. Emphasis is placed on the role of stable zinc in the reaction of the body to the administration of zinc-65. Some of the results of laboratory studies on the toxic effects of zinc-65 on animals, primarily rabbits, are presented. This volume is comprised of 18 chapters and opens with an overview of certain aspects of the toxicology of radioactive zinc-65, followed by a discussion on the behavior of zinc-65 in the rat body. Subsequent chapters explore the distribution of zinc-65 in the body of rabbits following chronic oral administration; bioelectrical activity of the cerebral cortex in rabbits in conditions of prolonged administration of radioactive zinc; the effect of prolonged internal irradiation with G5ZnCl2 on the functional state of the rabbit heart; and aspects of hemopoiesis following chronic intake of radiozinc. Morphological changes in experimental animals following chronic exposure to radioactive zinc are also considered. This book will be of interest to chemists and toxicologists.

  • Clinical Pharmacology

    Proceedings of the 7th International Congress of Pharmacology, Paris 1978
    • 1st Edition
    • P. Duchêne-Marullaz + 2 more
    • English
    Clinical Pharmacology provides a detailed discussion on toxicology. This discussion includes the chemotherapy of parasitic diseases. Some parts of the book focus on topics on immunopharmacology. Such topic as the genetic and environmental factors that contribute to individual’s varying response to drugs is explained. The book covers such topics as the methods and models for the isoniazid acetylation polymorphism. The issues that arise in the administration of drugs in the neonatal period are assessed. Another topic of interest is the effects of diseases on the absorption of drugs. The pharmacokinetic and pharmacodynamic characteristics of a drug are evaluated. The pharmacogenetic investigation amobarbital disposition is presented completely. The book then presents the use and consumption of drugs in different locations and some clinical considerations. The procedures and methods of analysis for such drug are also reviewed . The book can serve as a valuable tool for pharmacists, medical doctors, pediatricians, students, and researchers in the field of medicine.

  • The Equatorial Rain Forest

    A Geological History
    • 1st Edition
    • John R. Flenley
    • English
    The Equatorial Rain Forest: A Geological History presents the equatorial vegetation as a dynamic entity with varied and highly significant history. It also discusses other types of equatorial regions. It addresses the vegetational history from a palaeoecological viewpoint. Some of the topics covered in the book are the vegetation of equatorial regions; the prelude to the quaternary; the quaternary vegetation of equatorial Latin America; the quaternary vegetation of equatorial Africa; the cretaceous period; and the quaternary vegetation of equatorial indo-malesia. The value of vegetational history is fully covered. The effect of man on vegetation is discussed in detail. The text describes in depth the methods of studying vegetational history. The Paleocene, Eocene, and Oligocene epochs are presented completely. A chapter is devoted to the palynological evidence and synthesis. Another section focuses on the xeroseres, hydroseres and related successions. The book can provide useful information to botanists, geologists, students, and researchers.

  • Drugs in Psychiatric Practice

    • 1st Edition
    • Sam Stuart
    • English
    Drugs in Psychiatric Practice present a comprehensive examination of the drug treatment in psychiatry. It discusses certain ways in which drugs behaved. It addresses the advances in pharmacology and the basis of prescription. Some of the topics covered in the book are the classification of psychotropic drugs; basic principles of pharmacokinetics and drug metabolism; anti-schizophrenic drugs; evaluation of psychotropic drugs; unconventional chemotherapy; anti-parkinsonian and anti-dyskinetic drugs; introduction of amitriptyline; and tricyclic antidepressants. The role of tricyclic drugs in the treatment of enuresis and the drug treatment of organic brain syndrome are fully covered. An in-depth account of the monoamine oxidase inhibitors and amine precursors are provided. The tolerance and pharmacological dependence on alcohol are completely presented. A chapter is devoted to the factors involve in ethanol metabolism. Another section focuses on the unwanted effects of psychotropic drugs. The book can provide useful information to doctors, pharmacists, psychologists, students, and researchers.

  • Protein Contribution of Feedstuffs for Ruminants

    Application to Feed Formulation
    • 1st Edition
    • E.L. Miller + 2 more
    • English
    Protein Contribution of Feedstuffs for Ruminants: Application to Feed Formulation covers papers about the findings and knowledge on the ""Evaluation of the Protein Contribution of Feedstuffs for Ruminant"". The book presents papers about the recent advances in the knowledge of protein evaluation for ruminants; similarities and differences between rumen fermentation and postruminal utilization; and methods of assessing proteins for ruminants. The text also covers papers about protected proteins and amino acids for ruminants; validation and application of principles of protein evaluation for ruminants; practical feeding trials in Norway; and protein-energy interrelationships for growing and for lactating cattle. A report of co-ordinated trials carried out on commercial farms in the UK is also presented in the book. The text will be invaluable to feed compounders, research workers, advisors, farmers and agricultural students.

  • Soil Fungi and Soil Fertility

    An Introduction to Soil Mycology
    • 2nd Edition
    • S. D. Garrett
    • English
    Soil Fungi and Soil Fertility, Second Edition is an introduction to soil microbiology, incorporating significant advances in knowledge and understanding of the way micro-organisms live and function under laboratory and natural conditions. This book is comprised of nine chapters, discusses soil microbiology, and shows how the living ecosystem of the soil helps maintain soil fertility and crop production. This text begins with a description of the soil as a habitat, encompassing both its physical and chemical characteristics. The root systems, soil fauna, and soil micro-organisms or the Protist Kingdom all form the living inhabitants of the soil. The components of soil fungi from the organization and growth of its branching system called mycelium to the asexual reproduction and final dispersion are explained. This book also discusses genetic mechanisms in fungi and nuclear division that is a compensatory reduction in the number of chromosomes back to the haploid number that must occur. This text also presents a comparison of further studies of the fungal communities through microscopic and cultural methods, as well as other methods that would yield better soil fungi and soil fertility. Also considered are factors that affect the competitive saprophytic colonization of substrates by soil fungi, and then how these fungi exploit their colonized substrates for survival. This monograph then examines the root-infecting fungi through their ability to feed on living plant tissues and how a balanced host-parasite relationship actually benefits the fungi community.This book is suitable for soil mycologists, soil researchers, agriculturists, and university undergraduates interested in soil microbiology.

  • Recent Progress in Hormone Research - Volume 49

    Proceedings of the 1992 Laurentian Hormone Conference
    • 1st Edition
    • C. Wayne Bardin
    • English
    Among the topics covered in Volume 49 are neurotransmitter transporters circadian rhythms, transgenic model for studying isles development, protein phosphateses, the androgen receptor, molecular genetics of steroid 5oz-reductases and benign and malignant prostatic neoplasms.

  • Thyroid Disease and Muscle Dysfunction

    • 1st Edition
    • Ian Ramsay
    • English
    Thyroid Disease and Muscle Dysfunction covers the pioneering work of the author in the study of muscle dysfunction in patients with thyrotoxicosis. His contributions on this subject represent real advances in the understanding of metabolic muscle disease. This book is written to clarify the association between abnormalities of skeletal muscle and derangement of thyroid function. This book is organized into five chapters that describe the muscular abnormalities in people with hypothyroidism, explain the concepts of thyrotoxic periodic paralysis and thyrotoxic myopathy, discuss the association between thyroid disease and myasthenia gravis, and describe the changes in thyroid functions associated with miscellaneous muscle disorders. This book will be of interest to persons dealing with studies on the relation between thyroid disease and muscle dysfunction.

  • Neurosciences Research

    Volume 4
    • 1st Edition
    • S Ehrenpreis + 1 more
    • English
    Neuroscience Research, Volume 4 covers papers on a varied group of studies, ranging from synaptic transmission and local anesthetic action to the immobility reflex ("animal hypnosis") and control of food intake. The book presents papers on the mechanisms of synaptic transmission; the acetylcholine system and neural development; and the site of action and active form of local anesthetics. The text also includes papers on biological rhythms and their control in neurobehavioral perspective; neurophysiologic studies of the immobility reflex ("animal hypnosis" and the hepatic receptors and the neurophysiological mechanisms controlling feeding behavior. Neuroscientists, physiologists, and psychiatrists will find the book useful.

  • Ultrastructural Pathology of the Cell and Matrix

    A Text and Atlas of Physiological and Pathological Alterations in the Fine Structure of Cellular and Extracellular Components
    • 3rd Edition
    • Feroze N. Ghadially
    • English
    Ultrastructural Pathology of the Cell and Matrix: Third Edition Volume I present a comprehensive examination of the intracellular lesion. It discusses the analysis of pathological tissues using electron microscope. It addresses the experimental procedures made on the cellular level. Some of the topics covered in the book are the physiological analysis of the nucleus; nuclear matrix, interchromatin, and perichromatin granules; structure and function of centrioles; characteristics of mitochondria; Golgi complex in cell differentiation and neoplasia; and degranulation of rough endoplasmic reticulum. The intracytoplasmic and intranuclear annulate lamellae are fully covered. An in-depth account of the classification, history, and nomenclature of lysosomes are provided. The morphology and normal variations of melanosomes and anchoring fibrils are completely presented. A chapter is devoted to the endocytotic structures and cell processes. Another section focuses on the classification and nomenclature of fibrous components. The book can provide useful information to cytologists, scientists, students, and researchers.

  • Mechanisms of Drug Toxicity

    Proceedings of the Third International Pharmacological Meeting
    • 1st Edition
    • H. Rašková
    • English
    Mechanisms of Drug Toxicity, Volume 4 presents the proceedings of the 3rd International Pharmacological Meeting held in Sao Paulo, Brazil in 1966. The book discusses the drug-induced pathobiotic effects; the mechanisms of adverse reactions; and enzyme induction in the mechanism of chronic toxicity. The text also describes the influence of inducing substances on the growth of liver and microsomal electron transport systems; the quantitative aspects of chronic toxicity; and the facts and fallacies in predicting drug effects in human.

  • Irrigation and Agricultural Development

    Based on an International Expert Consultation, Baghdad, Iraq, 24 February - 1 March 1979
    • 1st Edition
    • S. S. Johl
    • English
    Irrigation and Agricultural Development compiles selected papers presented at the International Expert Consultation held in Baghdad, Iraq from February 24 to March 1, 1979. This book addresses the technical, economic, and institutional problems connected with the development and utilization of irrigation water for agricultural production. It discusses the policy framework for investment in irrigation projects; natural equilibriums and irrigated agriculture; and selection of appropriate irrigation methods for semi-arid regions. The studies on crop consumptive use of water in Iraq; world bank experience with irrigation, drainage and land reclamation projects; and salinity problems and land reclamation in the Arab Republic of Egypt are also covered. This publication is recommended for environmentalists, irrigation engineers, and agriculturists concerned with water development, conservation, and management.

  • Development of Anti-Asthma Drugs

    • 1st Edition
    • Derek R. Buckle + 1 more
    • English
    Development of Anti-Asthma Drugs reviews existing asthma treatments and novel approaches currently under investigation, in the context of their mode of action and clinical effectiveness, in the hope that this might lead to a greater understanding of the factors involved in the expression of the disease and, therefore, in the design of better drugs. It is planned based on the concept of the causes and treatment of asthma, This book is organized in three main parts. Part I deals with the nature of asthma, its pathological mechanisms, natural history and epidemiology. Part II discusses mediators associated with asthma including platelet-activating factor, leukotrienes and histamine. Part II covers pharmaceutical approaches in the development of anti-asthma drugs and includes sections on inhibitors of mediator release and competitive and functional antagonists. This book will be of interest to persons dealing with studies on anti-asthma drugs and those interested in pharmacological development.

  • Fats in Animal Nutrition

    • 1st Edition
    • J. Wiseman
    • English
    Fats in Animal Nutrition provides a useful text containing information from many diverse disciplines that discuss the nutritional utilization of lipids of domesticated animals. The book is divided into seven parts. Part I covers the chemistry and biochemistry of animal and plant fats and their nutritional importance; Part II discusses the general principles involved in the transport and absorption of fats and how this process is facilitated in ruminant and non-ruminant animals. The book also deals with the role of essential fats in the nutrition of different animals, as well as the protective functions of fat-soluble vitamins . Part IV discusses the use of fats as an energy source for animals; Part V deals with the inclusion of fats in animal feeds and their uses. The deposition of fat in different meats and the practical applications of fat utilization in animals are covered as well. The text is recommended for agriculturists, veterinarians, and zoologists who would like to know more about the importance of the inclusion of fats in animal diets.

  • Light and Plant Development

    • 1st Edition
    • H. Smith
    • English
    Light and Plant Development presents the Proceedings of the 22nd University of Nottingham Easter School in Agricultural Science. It discusses the spectral sensitivity of inhibition of flowering by light. It addresses the action spectrum for leaf enlargement and stem growth inhibition. Some of the topics covered in the book are the nature of the blue light photoreceptor in higher plants and fungi; re-examination of photochemical properties and absorption characteristics of phytochrome using high-molecular-weigh... preparations; and intermediates in the photoconversion of phytochrome. The high irradiance reaction is fully covered. The physiological evidence and localised responses, intracellular localisation and action of phytochrome are discussed in detail. The text describes in depth the immunological visualisation of phytochrome. The fractionation procedures and terminology are presented completely. A chapter is devoted to the photocontrol of enzyme levels. Another section focuses on the ribosomal RNA synthesis in developing leaves. The book can provide useful information to botanists, chemists, students, and researchers.

  • Antarctic Fish Biology

    Evolution in a Unique Environment
    • 1st Edition
    • Joseph T. Eastman
    • English
    This important volume provides an original synthesis and novel overview of Antarctic fish biology, detailing the evolution of these fish in some of the most unusual and extreme environments in the world. Focusing on one group of fish, the notothenoioids, which contain the majority of the current organismal diversity, this book describes a fauna that has evolved in isolation and experienced incredible adaptive radiation by acquiring numerous physiological specializations. Darwin's finches and African cichlids may be joined by Antarctic fishes as exemplars of adaptive radiation.The books' coverage is detailed and comprehensive, and the author clearly recognizes the fact that these fish are a component of a most interesting and biologically unique ecosystem and environment. Topics in Antarctic Fish Biology include past and present environments, fossil records, taxonomic composition of fauna, systematic relationships, diversification, and physiological adaptations.

  • Biological Oxidants: Generation and Injurious Consequences

    Volume 4
    • 1st Edition
    • Charles G. Cochrane + 1 more
    • English
    Biological Oxidants: Generation and Injurious Consequences is a collection of papers that describes research work done concerning molecules of the intracellular and plasma membrane generating system in leukocytes; the intracellular interactions in oxidant-induced cellular injury; malignant transformation; and intracellular mechanism of oxidant formation. One paper reviews biological oxidants and the molecular basis of chronic granulomatous disease, particularly on compositions found within the plasma membrane. One such composition concerns the discovery of a flavocytochrome b as the central electron-transportin... molecule in this system. Another paper examines the early injury of cells caused by external oxidants and the consequences of DNA damage. Other papers review the metabolism of vascular endothelial-derived reactive species, the calcium-modulated cellular effects of oxidants, as well as, the mechanism of inflammatory oxidant damage in tissues. This book is suitable for biochemists, microbiologists, and academicians whose works involve research of cell membranes.

  • Utilization of Nutrients During Postnatal Development

    International Series of Monographs in Pure and Applied Biology: Zoology
    • 1st Edition
    • P. Hahn + 1 more
    • G. A. Kerkut
    • English
    Utilization of Nutrients during Postnatal Development investigates the nutritional aspects of postnatal development, with emphasis on functions that in some way are closely connected to food, including food intake, digestion, transport, and metabolism. Topics covered range from energy sources and energy balance in starvation to the quantitative and qualitative aspects of food intake. The fate of carbohydrates in infant animals is also discussed, along with the metabolism of lipids during postnatal development. Comprised of eight chapters, this volume begins with an analysis of the most important differences between adult and suckling rats, paying particular attention to thermoregulation and the action of hormones in the early postnatal period. Subsequent chapters deal with the effect of starvation at two environmental temperatures on losses in body weight; protein as an energy source; the absorption of glucose from the gastrointestinal tract; and energy metabolism in the human fetus and newborn. The final chapter is devoted to the late effects of changes in diet composition during the weaning period. This book will be useful for students, practitioners, and researchers in physiology, biology, and developmental nutrition.

  • Comprehensive Insect Physiology, Volume 8

    Endocrinology II
    • 1st Edition
    • G. A. Kerkut
    • English
    Endocrinology II concerns the actions of hormones in insects, complementing Volume 7 which is concerned with the production and chemistry of insect hormones. While the preceding volume is directed mainly towards the insect endocrinologist, this volume has much of intrinsic interest to the general physiologist. It deals with the regulation of metabolism, reproduction, cuticle properties, and certain aspects of behaviour from a systems point of view and amply documents how hormones have provided basic insights into the functioning of such systems. Interference in endocrine regulation could provide future systems for insect control and this volume will provide the foundation on which the future formulation of these strategies is based. More information on diverse aspects of insect hormone action is brought together here than in any previous single work and this volume will therefore be a valuable reference source for many years to come.

  • The Biology of the Mollusca

    • 2nd Edition
    • R. D. Purchon
    • G. A. Kerkut
    • English
    Reviews the most important literature on the functional morphology and natural history of molluscs over a period of half a century, from 1925 to the present day, and draws extensively upon authoritative papers published mostly in the English language in a large number of international journals during this period. By these means it is hoped to provide an anthology of what is most interesting in the literature in a number of selected topics. Appendices give some practical assistance for the dissection of selected examples

  • In Vitro Biological Systems

    Methods in Toxicology, Vol. 1
    • 1st Edition
    • Charles A. Tyson + 1 more
    • English
    Methods in Toxicology, Volume 1: In Vitro Biological Systems, Part A provides basic techniques employed by widely recognized scientists to prepare and maintain the biological components of in vitro model systems. The book discusses the in vitro models of neural and neuromuscular systems; ocular system; respiratory system; cardiovascular system; and gastrointestinal system. The text also describes liver slices; liver hepatocytes; other liver cell systems; proximal tubule fragments; kidney cell culture; reproductive and developmental systems; immune system; and skin. Pharmacologists, toxicologists, cell biologists, physiologists, immunotoxicologists, and molecular toxicologists will find the book invaluable.

  • Water in Foods

    Fundamental Aspects and Their Significance in Relation to Processing of Foods
    • 1st Edition
    • Fito + 2 more
    • English
    Water in Foods: Fundamental Aspects and their Significance in Relation to Processing of Foods contains the proceedings of the Fifth International Symposium on the Properties of Water in Foods (ISOPOW-V), held in Peniscola, Valencia, Spain, on November 8-14,1992. Organized into 31 chapters, each chapter representing the papers presented in the meeting, this book begins with a review of the theoretical aspects of hydration. Some chapters follow discussing the basic physical chemistry and links between hydration and solute interactions; computer modeling studies of the interaction of water with carbohydrates; and theories of liquid-glass transition. This book also describes the NMR imaging in the study of diffusion of water in foods, mechanical properties of frozen model solutions, and the role of water in biomembrane structures. Other chapters relate water to the methods of food preservation.

  • Chemical Structure–Biological Activity Relationships: Quantitative Approaches

    Proceedings of the 3rd Congress of the Hungarian Pharmacological Society, Budapest, 1979
    • 1st Edition
    • F. Darvas
    • English
    Chemical Structure-Biological Activity Relationships: Quantitative Approaches, Volume III, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. This volume focuses on the methodological aspects of QSAR. It also aims to inform the reader about the QSAR research conducted in East-European countries. This volume contains 38 presentations organized into six sections. Several lecturers deal with ""real prediction"" cases, i.e. activity estimation prior to the synthesis of the compounds. A particularly abundant section is devoted to the question of how the receptor models can be built up by means of QSAR calculations. Other sections present mathematical models and algorithms which could be applied to improve further the effectiveness of QSAR calculations. As another unique feature, a separate section treats the quantitative aspects of peptide structure-activity relationships—a field seemingly backward despite its evident importance. Hydrophobicity and its influence on biological potency along with the relationship of steric properties and biological activity are also discussed.

  • Hazardous Waste Handbook for Health and Safety

    • 1st Edition
    • William F. Martin + 2 more
    • English
    Hazardous Waste Handbook for Health and Safety provides instructions and guidelines to supervisors responsible for occupational safety and health programs at hazardous waste sites. The manual presents the health and safety risks of hazardous waste sites; ways to implement and carry out hazardous waste site clean-up; preliminary basis for developing a specific health and safety program; and planning for and responding to emergencies involving hazardous materials. The book will be very useful to supervisors and safety engineers of hazardous waste sites.

  • Research in Protozoology

    In Four Volumes
    • 1st Edition
    • Tze-Tuan Chen
    • English
    Research in Protozoology is the third book in a four-volume series on protozoological research. Like the previous two, this volume covers the cytology, parasitology, fibrillar systems, and genetics of protozoans. This volume explores the immunological aspects of infections caused by protozoans, identifies the organisms that live in and on protozoans, and describes the pathogenic and metabolic pathway of protozon infections. It also discusses the protozoan fibrillar system and the macronucleus of ciliates. This book will be of interest to persons dealing with studies on the genetics aspects, cytology and parasitology of protozoans.

  • Joll's Diseases of the Thyroid Gland

    • 2nd Edition
    • Francis F. Rundle
    • English
    Joll's Diseases of the Thyroid Gland, Second Edition provides information pertinent to the fundamental aspects of thyroid diseases. This book discusses the physiology structure, and development of the thyroid gland. Organized into 29 chapters, this edition begins with an overview of the function of the thyroid gland to trap and concentrate iodine, harness it in organic combination, and then to secrete it into the blood. This text then discusses the evolutionary scheme showing the development of thyroid gland as a special organ for the control of iodine metabolism. Other chapters consider the various types of thyroid diseases, including simple goiter, acute inflammations, Grave's disease, and granulomatous diseases of the thyroid. This book discusses as well the etiological or clinico-pathological basis of the classification of simple goiter. The final chapter deals with the post-operative complications of thyroidectomy and their treatment. This book is a valuable resource for physicians, surgeons, and clinical researchers.

  • Advances in Pharmacological Research and Practice

    Proceedings of the 4th Congress of the Hungarian Pharmacological Society, Budapest, 1985
    • 1st Edition
    • J. Knoll + 1 more
    • English
    Advances in Pharmacological Research and Practice, Volume 1: Pharmacological Protection of the Myocardium presents the proceedings of the 4th Congress of the Hungarian Pharmacological Society, held in Budapest, Hungary in 1985. This book presents a comprehensive view of the development in the fields of pharmacological protection of the myocardium and the pharmacology of the vascular system. Organized into two sections encompassing 70 chapters, this volume begins with an overview of the ischemic biochemical changes with emphasis on the role of cAMP and the protein kinase system. This text then explores the cellular electrophysiological disorders seen in acute myocardial ischemia as well as their pharmacological modification. Other chapters consider the prevention of primary ventricular fibrillation that includes measures aimed at maintaining electrical stability. The final chapter deals with drugs affecting beneficially the pathological lipoprotein levels. This book is a valuable resource for cardiologists and pharmacologists.

  • Human Afflictions and Chromosomal Aberrations

    International Series of Monographs in Pure and Applied Biology: Modern Trends in Physiological Sciences
    • 1st Edition
    • Raymond Turpin + 1 more
    • P. Alexander + 1 more
    • English
    Modern Trends in Physiological Sciences, Volume 32: Human Afflictions and Chromosomal Aberrations presents the study of the links between chromosome aberrations and physical and mental congenital anomalies. This book discusses the possibilities of human cytogenetic research as well as its difficulties. Organized into 15 chapters, this volume begins with an overview of the development of human chromosome investigations. This text then explains the methods for studying human chromosomes, which can be applied without controlling the atmosphere of the incubator. Other chapters describe the structural features of the normal human karyotype. This book discusses as well the early appearance of a chromosome aberration that produces a change in the hereditary patrimony manifest in a constitutional disorder of the individual. The final chapter deals with the biochemical effects that correspond to numerical or structural anomalies in chromosome 21. This book is a valuable resource for genetecists, cytogeneticists, physicians, and clinical researchers.

  • The Molecular Properties and Evolution of Excitable Cells

    International Series of Monographs in Pure and Applied Biology
    • 1st Edition
    • C. J. Duncan
    • G.A. Kerkut
    • English
    The Molecular Properties and Evolution of Excitable Cells describes the theoretical aspects in which excitable cells, such as nerves, muscles, and sense organs, operate. This book develops a hypothesis regarding the evolution and characteristics of excitable cells. This monograph focuses on the properties of the bounding membrane and its complex permeability system, which starts the excitation state. Sense organs, as the input component in both vertebrates and invertebrates, are then discussed. The text then briefly describes the ways that the ionic permeability of the excitable membrane can both be modified and controlled. The book points out that since ions pass through standard sizes of the pores in an excitable membrane, their passage is determined by the dimensions of the pore and by the existing charge found on its walls. The book then explains the application of a mechanical stimulus to a mechanoreceptor that will cause deformations in the membrane. This deformation leads to enzyme activity and produces alteration in the rate at which ATP is supplied to the lateral borders of the cell. The text discusses a hypothesis that invokes enzyme activity by propagating action potential along the axon, and other input systems, such as adrenaline, amino acids, and y-amino-butyric acid (GABA). The book also explains the hypothesis that living organisms are composed of an ordered system of protein-enzymes forming on phospholipid-protein membranes. This monograph will benefit microbiologists, biotechnologists, and academicians connected with the biological sciences.

  • Pharmacology of the Coronary Circulation

    Volume 10
    • 1st Edition
    • Natalia V. Kaverina
    • English
    Pharmacology of the Coronary Circulation focuses on the effects of pharmacological substances on the circulation of the heart, physiology of coronary circulation, effects of adrenomimetic, cholinergic, and ganglion-blocking agents, phenothiazine derivatives, analgesics, nitrites, and nitrates on cardiac vessels and results of clinical trials on Chloracizine. The publication first offers information on the physiology of the coronary circulation and the effects of pharmacological substances on the coronary circulation, including myotropic and neutropic substances and other substances. The book then examines the effects of adrenomimetic substances and cholinergic substances on the coronary circulation. The manuscript evaluates the effects of ganglion-blocking substances and analgesic substances on the coronary circulation. Topics include nicotine, etraethylammonium, hexamethonium, pentamine, and mecamine. The publication then takes a look at the effects of phenothiazine derivatives on the coronary circulation; importance of reflex reactions in connection with the development of acute coronary insufficiency; and effects of pharmacological substances on reflex reactions in the coronary vessels. The book is a dependable reference for readers interested in the pharmacology of the coronary circulation.

  • Evaluating Alcohol and Drug Abuse Treatment Effectiveness

    Recent Advances
    • 1st Edition
    • Linda Carter Sobell + 2 more
    • English
    Evaluating Alcohol and Drug Abuse Treatment Effectiveness: Recent Advances is a collection of papers that covers the advancement in rehabilitation of individuals with a history of substance abuse. The title aims to find ways in identifying the treatment that best fits a specific patient. The text first provides a historical account of alcohol and drug treatment outcome research. Next, the selection considers the use of multiple measures of life health to assess alcohol treatment. Chapter 3 deals with the behavioral assessment and treatment evaluation of narcotic addiction, while Chapter 4 talks about the evaluation of behavioral and traditional treatment of alcoholics. The fifth chapter tackles the contingency contracting with drug abusers, and the sixth chapter covers the development of a prototype for the evaluation of alcohol treatment. The text also details the problems in alcohol treatment along with the improvement of confidence in treatment of substance abuse. The book will be of great use to behavioral scientists, social workers, and mental health specialists.

  • Secondary Plant Products

    A Comprehensive Treatise
    • 1st Edition
    • Volume 7
    • Walter Stumpf + 1 more
    • English
    The Biochemistry of Plants: A Comprehensive Treatise, Volume 7: Secondary Plant Products focuses on the biochemistry of secondary compounds, including tissue culture and differentiation, complexes, and plant systematics. The selection first elaborates on the physiological roles of secondary natural products, tissue culture and the study of secondary natural products, and turnover and degradation of secondary natural products. Discussions focus on degradative reactions of nitrogenous and phenolic compounds, concept of turnover of secondary products, and plant-vertebrate interactions. The text then elaborates on secondary plant products and cell and tissue differentiation; compartmentation in natural product biosynthesis by multienzyme complexes; and secondary metabolites and plant systematics. The manuscript examines the stereochemical aspects of natural products biosynthesis, nonprotein amino acids, and amines. Topics include tryptamines, phenethylamines, and histamine, nonprotein amino acids as analogues and antimetabolites, chemistry and biogenesis, and nonprotein amino acids as indexes for chemotaxonomy. The book also tackles glycosylation and glycosidases; transmethylation and demethylation reactions in the metabolism of secondary plant products; and oxygenases and the metabolism of plant products. The selection is a vital reference for researchers interested in the biochemistry of secondary compounds.

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