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    • Side Effects of Drugs Annual

      • 1st Edition
      • Volume 45
      • October 30, 2023
      • English
      • Hardback
        9 7 8 0 4 4 3 1 9 3 9 6 5
      • eBook
        9 7 8 0 4 4 3 1 9 3 9 7 2
      Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions, Volume 45, first published in 1977, presents clinicians and medical investigators with a critical survey of new data and trends in adverse drug reactions and interactions. Topics covered include ADRs, ADEs and SEDs: A Bird’s Eye View, Lithium, Drugs of abuse, Side effects of drugs used in the treatment of Alzheimer's disease, Sedatives and hypnotics, Antipsychotic agents, Anti-epileptic Medications, Side effects of opioid analgesics and narcotic antagonists, Anti-inflammatory and antipyretic analgesics and drugs used in gout, Side effects of local anesthetics and therapeutic gases, and more. Other sections covered include Antihistamines (H1 receptor antagonists), Drugs that act on the respiratory tract, Positive inotropic drugs and drugs used in dysrhythmias, Beta adrenergic antagonists and antianginal drugs, Drugs acting on the cerebral and peripheral circulations, Antihypertensive drugs, and much much more.

    • Neurophysiology of Silence Part A: Empirical Studies

      • 1st Edition
      • Volume 277
      • June 6, 2023
      • English
      • Hardback
        9 7 8 0 3 2 3 9 9 5 5 1 1
      • eBook
        9 7 8 0 3 2 3 9 9 5 5 2 8
      Neurophysiology of Silence, Volume 277 in the Progress in Brain Research series, highlights new advances in the field, including chapters on Mindfulness, mind wandering and creativity, The cloud of unknowing: Cognitive dedifferentiation in whole-body perceptual deprivation, Embodying abstract concepts: the connection between meditation, empathy and introception, Measures of music-like experience emergent in a sonic ganzfeld: an example of perceptual structuring on the edge of silence, Doing out of silence: The effects of visual art on verbal creativity, Cessation experiences during meditation, The psychophysiology of covert behavior during goal directed behavior, and much more.

    • Advances in Stem Cells and their Niches

      • 1st Edition
      • Volume 7
      • September 25, 2023
      • Susie Nilsson
      • English
      • Paperback
        9 7 8 0 4 4 3 1 9 3 5 2 1
      • eBook
        9 7 8 0 4 4 3 1 9 3 5 3 8
      Advances in Stem Cells and their Niches, Volume Seven highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

    • Handbooks of Cognitive Behavioral Therapy

      • 1st Edition
      • April 19, 2023
      • Colin R. Martin + 2 more
      • English
      • Hardback
        9 7 8 0 4 4 3 1 8 5 5 6 4
      • eBook
        9 7 8 0 4 4 3 1 8 5 5 8 8
      Handbook of Cognitive Behavioral Therapy by Disorder: Case Studies and Application for AdultsPregnancy, childbirth, childhood, adolescence, and aging can be beset with adverse changes in psychobiology and behavior. Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging will better readers’ understanding of a variety of conditions and the applicability of CBT therapy as a treatment. Featuring chapters on postnatal anxiety and depression, insomnia, and dysmorphia, the book discusses in detail the use of cognitive behavioral therapies in the treatment of these issues affecting individuals at the start and end of their lives. With expert authors from the clinical field, the book has applicability for behavioral scientists, psychologists, cognitive and behavioral neuroscientists, and anyone working to better understand and treat using cognitive behavioral therapies.Handbook of Lifespan Cognitive Behavioral Therapy: Childhood, Adolescence, Pregnancy, Adulthood, and Aging Mental illness and the variety of conditions, disorders, and phobias associated with it impact not only the individual but also the family unit, the community, and society at large. Handbook of Cognitive Behavioral Therapy by Disorder: Case Studies and Application for Adults will better readers’ understanding of a variety of these conditions in adults specifically and the applicability of CBT therapy as a treatment. Featuring chapters on schizophrenia, bipolar disorder, dysmorphia, depression, and anxiety, the book discusses in detail the use of cognitive behavioral therapies in the treatment of these issues in adults. With expert authors from the clinical field, the book has applicability for behavioral scientists, psychologists, cognitive and behavioral neuroscientists, and anyone working to better understand and treat using cognitive behavioral therapies.

    • Natural Products

      • 1st Edition
      • Volume 61
      • November 15, 2023
      • English
      • Hardback
        9 7 8 0 4 4 3 1 3 7 0 9 9
      • eBook
        9 7 8 0 4 4 3 1 3 7 1 0 5
      Natural Products, Volume 61 in the Annual Reports in Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on Chemical evolution of natural product structure for drug discovery, Fungal Metabolites, Polypharmacology of Natural Products, Glycopeptide Antibiotics, and Natural products-based drug discovery for the CNS.

    • Advances in Clinical Chemistry

      • 1st Edition
      • Volume 114
      • June 1, 2023
      • Gregory S. Makowski
      • English
      • Hardback
        9 7 8 0 4 4 3 1 9 2 8 8 3
      • eBook
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      Advances in Clinical Chemistry, Volume 114, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. New sections in the updated release include Growth differentiation factor 15 (GDF-15) in kidney diseases, Alkaptonuria - past, present and future, Alcohol Consumption and Nutritional Biomarkers in Early-Stage Alcohol-Associated Liver Disease, Advances in Liquid Biopsy–Based Markers in NSCLC, D-dimer testing: a narrative review, Evolving Markers in Amyotrophic Lateral Sclerosis, and more.

    • Pancreatic Cancer: Basic Mechanisms and Therapies

      • 1st Edition
      • Volume 159
      • May 31, 2023
      • English
      • Hardback
        9 7 8 0 4 4 3 1 3 3 5 4 1
      • eBook
        9 7 8 0 4 4 3 1 3 3 5 5 8
      Pancreatic Cancer: Basic Mechanisms and Therapies, Volume 159 in the Advances in Cancer Research, presents the latest release in this ongoing, well-regarded serial with invaluable information on the exciting and fast-moving field of cancer research. Pancreatic cancer (PC) is the third leading cause of cancer-related deaths in the United States. Greater than 90% PCs are Pancreatic ductal adenocarcinomas (PDAC) which have a dismal estimated 5-year overall survival of only 11%. PDAC is predicted to become the second leading cause of mortality in the United States by 2030. In the clinic, the PDAC patients often present with incurable disease at the time of first diagnosis. This cancer is particularly lethal because of its propensity to spread quickly to distant organs including the lymphatic system. PDAC metastasis occurs shortly after tumor initiation and is caused by a complex interaction between autonomous tumor cells and cellular elements of the tumor microenvironment. Although PDAC remains a challenging disease to treat and a leading cause of cancer-related deaths, progress is being made in disease etiology and pathogenesis, and intensive research is focused on developing optimal treatment approaches for patients. Considering the continuous progress being made in understanding PDAC pathogenesis and designing new therapies, it was considered timely to develop an up-to-date thematic issue of Advances in Cancer Research (ACR) focused on PDAC. In this thematic issue, we have included ten review articles by experts that cover cancer disparities, PDAC pathobiology, the roles of the tumor microenvironment, tumor heterogeneity, PC stem cells, genetic and signaling events critical for PDAC pathogenesis, Immunotherapy and chemoresistance in PDAC, and different PDAC mouse models. This special issue highlights recent research progress in PDAC, which bridges the gap between basic and clinical research.

    • The Immunological Synapse Part A

      • 1st Edition
      • Volume 173
      • January 11, 2023
      • English
      • Hardback
        9 7 8 0 3 2 3 9 0 1 5 4 3
      • eBook
        9 7 8 0 3 2 3 9 0 1 5 5 0
      The Immunological Synapse, Part A, Volume 173 in the Methods in Cell Biology series provides state-of-the-art methods for the study of the immunological synapse. Sections cover Imaging polarized granule release at the cytotoxic T cell immunological synapse using TIRF microscopy: control by polarity regulators, Analysis of centrosomal area actin reorganization and centrosome polarization upon lymphocyte activation at the immunological synapse, P815-based redirected degranulation assay to study human NK cell effector functions, Cytotoxic and Chemotactic Dynamics of Natural Killer Cells Quantified by Live-cell Imaging, Quantification of interaction frequency between antigen-presenting cells and T cells by conjugation assay, and more. Other chapters focus on the Study of the Effects of NK-Tumor Cell Interaction by Proteomic Analysis and Imaging, Quantification of lymphocytic choriomeningitis virus specific T cells and LCMV viral titers, Quantification of lymphocytic choriomeningitis virus specific T cells and LCMV viral titers, An in vitro model to monitor natural killer cell effector functions against primary breast cancer, and Standardized Protocol for the Evaluation of Chimeric Antigen Receptor (CAR)-modified Cell Immunological Synapse Quality using the Glass-supported Planar L.

    • Special Volume on Kogia biology Part 1

      • 1st Edition
      • Volume 96
      • November 15, 2023
      • English
      • Hardback
        9 7 8 0 0 8 1 0 2 9 1 8 3
      • eBook
        9 7 8 0 0 8 1 0 2 9 1 9 0
      Special Volume on Kogia biology presents in-depth and up-to-date reviews on all aspects of marine biology. Published since 1963, this serial updates on a variety of topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography.

    • Modifications and Targeting of Protein Termini Part A

      • 1st Edition
      • Volume 684
      • May 23, 2023
      • English
      • Hardback
        9 7 8 0 4 4 3 1 5 7 7 2 1
      • eBook
        9 7 8 0 4 4 3 1 5 7 7 3 8
      Modifications and Targeting of Protein Termini, Volume 684 in the Methods in Enzymology series serial highlights new advances in the field, with this new volume presenting interesting chapters pn a variety of timely topics, including Optimizing purification and activity assays of N-terminal methyltransferase complexes, In vitro reconstitution of hierarchical steps of Arg/N-degron pathway, Identification of N-degrons and N-recognins by using peptide-pull-downs combined with quantitative proteomics, A decoupled Virotrap approach to study the interactomes of N-terminal proteoforms, Monitoring ADO-dependent proteolysis in cells using fluorescent reporter proteins, Site-specific α-N-terminal methylation on peptides through chemical and enzymatic methods, and more. Additional sections cover Monitoring the interactions between N-degrons and N-recognins of the Arg/N-degron pathway, Characterization and chemical modulation of p62/SQSTM1 as an autophagic N-recognin of the Arg/N-degron pathway, Analysis of higher plant N-degron pathway components and substrates via expression in S. cerevisiae, and so much more.

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